Dr. Benton studies colorectal cancer, particularly focusing on the KRAS G12V mutation, which is a change in the DNA that can affect how the cancer develops and responds to treatment. He examines how this mutation alters the metabolism of cancer cells, making them dependent on a specific protein called ACSS2. By understanding these relationships, his research seeks to identify better treatment strategies for patients with this genetic mutation, which can lead to more effective therapy options.
Key findings
The KRAS G12V mutation in colorectal cancer cells shows a strong dependence on ACSS2, indicating that blocking this protein could enhance treatment effectiveness.
Targeting ACSS2 in colorectal cancer cells with the KRAS G12V mutation could lead to improved clinical outcomes for patients, as these cells are more vulnerable when ACSS2 is inhibited.
The study demonstrates that specific mutations in cancer can significantly alter the way cells metabolize energy, offering a route for developing targeted therapies.
Frequently asked questions
Does Dr. Benton study colorectal cancer?
Yes, Dr. Benton specializes in colorectal cancer, focusing on specific genetic mutations like KRAS G12V.
What treatments has Dr. Benton researched?
He has researched treatments that target the ACSS2 protein in cells with the KRAS G12V mutation, aiming to improve how these cancer cells respond to therapies.
Is Dr. Benton’s work relevant to patients with KRAS mutations?
Yes, his research directly benefits patients with the KRAS G12V mutation in colorectal cancer by identifying potential new treatment strategies.
Publications in plain English
AI-enhanced culturally tailored intervention for Latino family caregivers of persons living with dementia: a feasibility study.
Plain English Researchers studied a support program called CONFIDENCE designed to help Latino family caregivers of people with dementia manage financial stress. They found that about 51% of the caregivers registered for an app that was meant to increase their connection and attendance to group sessions. Caregivers who used the app attended an average of 2.9 sessions, compared to 2.0 sessions for those who didn't use the app. This is important because it shows that using technology can help caregivers participate more in support programs, making it easier for them to cope with their demanding roles.
Who this helps: Latino family caregivers of individuals living with dementia.
Second-order correlation learning in 2- to 4-year-old children, and its underlying mechanism.
2026
Journal of experimental child psychology
Benton DT
Plain English This study looked at how 2- to 4-year-old children can learn about indirect relationships between objects when faced with a more complicated set of items. The researchers found that even 2-year-old children can identify these indirect connections and use them to make decisions about causation. This is important because it shows that young children have advanced thinking skills that can help them make sense of their surroundings.
Who this helps: This benefits parents and educators by highlighting children's cognitive abilities at a young age.
An associative-learning account of how infants learn about causal action in animates and inanimates: A critical reexamination of four classic studies.
2025
Journal of experimental psychology. General
Benton DT
Plain English This study explored how infants learn to understand cause and effect in both living things and everyday objects. The researchers found that infants can grasp these concepts not just from innate knowledge but also through general learning processes. In simulations, they showed that simply using associative learning could explain the findings from four earlier studies involving infants' understanding of causality.
Who this helps: This helps researchers and educators who work with infants and are interested in cognitive development.
Lessons from a Pilot Study of a Culturally Tailored Financial Well-Being Intervention Among Latino Family Caregivers.
2025
Journal of applied gerontology : the official journal of the Southern Gerontological Society
Meyer K, Mage SM, Gonzalez A, Zauszniewski JA, Rhodes S +5 more
Plain English This study focused on helping Latino family caregivers reduce their financial stress through a special program designed for their cultural needs. Researchers found that after participating in the program, 20 caregivers reported less financial strain two months later, with a significant improvement shown by a p-value of 0.013. This is important because financial stress can heavily impact the well-being of caregivers, which affects their ability to care for their loved ones effectively.
Who this helps: This benefits Latino family caregivers striving for better financial stability and support.
Low and high glycemic index drinks differentially affect sleep polysomnography and memory consolidation: A randomized controlled trial.
2025
Nutrition research (New York, N.Y.)
Gaylor CM, Brennan A, Blagrove M, Tulip C, Bloxham A +4 more
Plain English This study looked at how different types of sugary drinks, specifically low glycemic index (LGI) and high glycemic index (HGI), affect sleep and memory. Researchers found that after consuming an LGI drink, participants had more deep sleep (28.71% vs. 23.99%) and retained more neutral story content during memory tests (0.63 words vs. -10.13 words) compared to the HGI drink, but this effect only occurred when the LGI drink was consumed after the HGI drink. These results highlight that the type of carbohydrates eaten before bed can influence both sleep quality and memory.
Who this helps: This helps patients and anyone seeking to improve their sleep and memory through diet.
A feasibility study of: an elder mistreatment intervention for family caregivers of persons living with dementia.
2025
Journal of elder abuse & neglect
Meyer K, Yonashiro-Cho J, Zauszniewski J, Burant C, Mosqueda L +2 more
Plain English This study looked at a program designed to help family caregivers of people with dementia reduce mistreatment and improve their relationships. Out of 45 caregivers who started the program, 37 completed it, showing an 82% retention rate. Results showed significant improvements, with a decrease in psychological mistreatment and relationship strain, as well as an increase in caregivers' resourcefulness.
Who this helps: This benefits family caregivers of individuals living with dementia.
Laboratory development and validation of vapor phase PFAS methods for soil gas, sewer gas, and indoor air.
2025
Environmental science: atmospheres
Hayes H, Lutes C, Watson N, Benton D, Hanigan DJ +6 more
Plain English Researchers developed and tested a new method to measure specific chemical compounds (PFAS) in soil gas, sewer gas, and indoor air. They found that while their technique worked well for some PFAS, like fluorotelomer alcohols, it led to issues with accurately measuring others, such as perfluorooctanoic acid (PFOA), which was found to break down during the testing. This matters because having reliable methods for measuring PFAS can help track and manage potential environmental and health risks associated with these chemicals.
Who this helps: This helps scientists and environmental health officials working to monitor and minimize PFAS exposure.
Acceptability of a Web-Based Financial Education Intervention for Latino Caregivers: Mixed Methods Evaluation.
2025
JMIR formative research
Mage S, Benton D, Wilber K, Aguila Rodriguez R, Silva D +3 more
Plain English This study looked into how well Latino caregivers of people with dementia respond to an online program called CONFIDENCE, which teaches financial skills to help reduce their financial stress. The results showed that 96% of participants enjoyed the program, and all of them would recommend it to others; they reported feeling more confident in making financial decisions and less stressed about money. This matters because these caregivers spend nearly half of their income on care, and tailored support can make a significant difference in their financial well-being.
Who this helps: Latino caregivers of individuals living with dementia.
Acceptability of an Intervention to Prevent Older Adult Mistreatment Among Family Caregivers to Persons With Dementia: Multimethod Pilot Study.
2025
JMIR formative research
Meyer K, Wei W, Yonashiro-Cho J, Mage S, Kim S +6 more
Plain English This study looked at a new program called KINDER, aimed at preventing emotional mistreatment of older adults with dementia by their family caregivers. Out of 98 caregivers who participated, 72% completed a survey, with 80% of them saying they were very satisfied with the program and over 80% valuing the added group discussions very highly. This matters because high levels of satisfaction indicate that caregivers found the KINDER program useful and supportive, which can lead to better mental health for both caregivers and the older adults they care for.
Who this helps: This helps family caregivers of older adults with dementia.
Development of a theory-based intervention to prevent abuse of older adults.
2025
Journal of elder abuse & neglect
Meyer K, Zauszniewski JA, Wei W, Gassoumis Z, Gonzales A +3 more
Plain English This study focused on creating a new program to help stop emotional abuse of older adults, especially those with dementia, by their family caregivers. After interviewing 7 caregivers and refining the program, they tested it with 71 participants, who reported improved skills for managing caregiving challenges. These findings show that the developed program is effective in boosting caregivers’ abilities and ensuring better care for older adults.
Who this helps: This helps family caregivers and older adults, particularly those living with dementia.
System calibration for single-wavelength multi-terabit mode-division multiplexing free-space optical communication systems.
2025
Optics express
Li Y, Fernandes G, Benton D, Billaud A, Fernandes M +3 more
Plain English This study looked at improving a type of wireless communication that uses light to send data, specifically focusing on a new method to reduce confusion between different signals. The researchers managed to achieve a new record in data transfer by getting an impressive speed of 4.49 terabits per second using advanced techniques. This matters because faster data transmission can enhance communication systems, making them more effective for various applications.
Who this helps: This helps technology companies and researchers working on high-speed communication systems.
Validation of wellbeing scales among informal caregivers of Latinos with Alzheimer's disease and related dementias.
2025
Hispanic journal of behavioral sciences
Perales-Puchalt J, Checa I, Espejo B, de la C Martín Carbonell M, Fracachán-Cabrera M +16 more
Plain English This study looked at various wellbeing measures for Latino caregivers of individuals with Alzheimer's and related dementias, a population that hasn't been thoroughly studied before. Out of 100 caregivers, the researchers found that most scales were reliable and valid, with 19 out of 21 measures showing significant correlations. This means the tools used can accurately assess the wellbeing of Latino caregivers, which is important for providing better support and care.
Who this helps: This helps Latino caregivers of patients with Alzheimer's, as well as the healthcare professionals supporting them.
Subjective Financial Strain and Objective Financial Impacts Among Informal Caregivers in the United States.
2025
Journal of applied gerontology : the official journal of the Southern Gerontological Society
Zhu Y, Falzarano F, Mage S, Benton D, Wilber K +1 more
Plain English This study looked at how financial difficulties affect informal caregivers—people who provide unpaid care to older adults—across the U.S. It found that caregivers who help with more daily tasks, like cooking and cleaning, feel more financial strain and face greater financial challenges. Specifically, those seeking financial help increased their odds of experiencing these issues significantly. This is important because it highlights the need for better financial support for caregivers who take on many responsibilities.
Who this helps: This benefits informal caregivers who are supporting elderly family members or friends.
A Recipe for Resilience: A Systematic Review of Diet and Adolescent Mental Health.
2025
Nutrients
Tucker JE, Brennan AM, Benton D, Young HA
Plain English This study looked at how diet affects the mental health of teenagers aged 10-19. It reviewed 19 studies and found that healthy diets, like those rich in omega-3s and Mediterranean foods, were linked to fewer symptoms of depression. In contrast, poor diets were associated with higher levels of psychological distress. Understanding the connection between diet and mental health is important for developing effective strategies to help improve the well-being of young people.
Who this helps: This benefits adolescents struggling with mental health issues and the healthcare professionals supporting them.
KRAS G12V mutation-selective requirement for ACSS2 in colorectal adenoma formation.
2025
Cell reports
Budagyan K, Cannon AC, Chatoff A, Benton D, Kurimchak AM +6 more
Plain English This study focused on how a specific type of KRAS mutation, called KRAS G12V, affects cell metabolism in colorectal cancer. Researchers discovered that cells with this mutation rely heavily on a protein called ACSS2 for growth, making them more vulnerable to certain treatments when ACSS2 is blocked. They found that targeting ACSS2 could help improve treatment effectiveness for patients with this mutation, which is important because different mutations can respond differently to therapies.
Who this helps: This research benefits patients with KRAS G12V colorectal cancer.
"I Lay Awake at Night": Latino Family Caregivers' Experiences Covering Out-of-Pocket Costs When Caring for Someone Living With Dementia.
2024
The Gerontologist
Mage S, Benton D, Gonzalez A, Zaragoza G, Wilber K +2 more
Plain English This study looked at the financial challenges faced by Latino caregivers who care for family members with dementia. It found that, while caregivers generally spend about 25% of their income on caregiving, Latino caregivers often spend nearly 50%, leading to significant mental and physical stress. Understanding these challenges is crucial because the number of Latinos with dementia is expected to rise significantly in the coming decades, and better support is needed for these families.
Who this helps: This helps Latino families, caregivers, and healthcare providers.
Don't throw the associative baby out with the Bayesian bathwater: Children are more associative when reasoning retrospectively under information processing demands.
2024
Developmental science
Benton DT, Kamper D, Beaton RM, Sobel DM
Plain English This study looked at how 5- and 6-year-old children decide if one object causes another, especially when they have to think back on earlier information after learning new details. Researchers found that the kids were able to change their ideas about causes when there was little information to process, but struggled to do so when the information became more complex. The findings suggest that kids rely more on simple learning connections rather than complex thinking methods to understand causes.
Who this helps: This helps educators and parents understand how children learn about causes and effects.
Early exposure to sugar sweetened beverages or fruit juice differentially influences adult adiposity.
2024
European journal of clinical nutrition
Benton D, Young HA
Plain English This study looked at how drinking sugary drinks, like soda and fruit juice, before the age of two affects a person's weight and body fat later in life. Researchers found that those who drank soda early had higher body fat and a higher body mass index (BMI) by age 24, while early apple juice drinkers had lower body fat, especially among females. This matters because it shows that what children drink in their early years can influence their health and weight in adulthood, suggesting that better drink choices could lead to healthier outcomes.
Who this helps: This research helps parents and caregivers in making better dietary choices for young children.
Defining a vitamin A5/X specific deficiency - vitamin A5/X as a critical dietary factor for mental health.
2024
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition
Bánáti D, Hellman-Regen J, Mack I, Young HA, Benton D +5 more
Plain English This research looked at a new form of vitamin A called vitamin A5/X, found mainly in vegetables, and how it affects brain health. The study found that vitamin A5/X is crucial for activating important signals in the body related to dopamine, brain protection, and clearing harmful substances, which are all vital for good mental health and preventing nervous system diseases. Ensuring we get enough vitamin A5/X could help maintain a healthy brain and prevent issues like drug addiction and other neurological disorders as we age.
Who this helps: This helps patients, particularly those concerned about mental health and neurological diseases.
Alignment of Consumers' Expected Brain Benefits from Food and Supplements with Measurable Cognitive Performance Tests.
2024
Nutrients
Young HA, Cousins AL, Byrd-Bredbenner C, Benton D, Gershon RC +4 more
Plain English This study looked at whether the cognitive benefits people expect from food and supplements match up with standardized tests measuring those improvements. Researchers found that established tests can evaluate some specific areas like focused attention and memory, but new tests are needed for areas like future planning and creativity. These findings are important because they help bridge the gap between what consumers want and the science behind nutrition, leading to better dietary recommendations.
Who this helps: This helps consumers looking for effective dietary changes and supplements.
Synergistic effect of PAK and Hippo pathway inhibitor combination in NF2-deficient Schwannoma.
2024
PloS one
Benton D, Yee Chow H, Karchugina S, Chernoff J
Plain English This study looked at treating a genetic disorder called Neurofibromatosis type 2 (NF2) that causes tumor growth, specifically focusing on Schwannoma tumors. Researchers discovered that using a combination of two drug types—one that slows tumor growth (PAK inhibitors) and one that encourages tumor cell death (Hippo pathway inhibitors)—works better together than trying to use either one alone. They found this combination effectively reduced cell growth in multiple tests on NF2-deficient Schwannoma cells.
Who this helps: This benefits patients with Neurofibromatosis type 2 and their doctors by providing a potentially more effective treatment option for their tumor growth.
Validation of dementia care-related scales among informal caregivers of Latinos with dementia or mild cognitive impairment.
2024
medRxiv : the preprint server for health sciences
Perales-Puchalt J, Checa I, Espejo B, de la C Martín Carbonell M, Fracachán-Cabrera M +16 more
Plain English This study looked at the effectiveness of various tools for measuring dementia care given by informal caregivers to Latinos in the US. Researchers analyzed data from 100 caregivers and found that 19 out of 21 tested relationships between the scales showed significant results. The scales are now reliable for helping understand and improve care in this community, making them valuable for both research and clinical use.
Who this helps: This benefits Latino patients with dementia and their caregivers.
A cyclic peptide toolkit reveals mechanistic principles of peptidylarginine deiminase IV regulation.
2024
Nature communications
Bertran MT, Walmsley R, Cummings T, Aramburu IV, Benton DJ +14 more
Plain English Researchers studied how a protein called PADI4, which plays a role in immune responses and is linked to conditions like autoimmunity and cancer, is regulated within cells. They developed a set of tools that includes specific molecules that can either activate or inhibit PADI4, discovering a particular inhibitor (PADI4_3) that targets the active form of PADI4. This new understanding helps in exploring how PADI4 functions in various health issues, enabling better strategies for controlling its effects in diseases.
Who this helps: This benefits patients with autoimmune diseases, cancer, and other related health conditions.
Multi-nutrient interventions and cognitive ageing: are we barking up the right tree?
2023
Nutrition research reviews
Young HA, Geurts L, Scarmeas N, Benton D, Brennan L +6 more
Plain English This study reviewed how combining different nutrients might affect brain health as we age, instead of focusing on single foods. The experts identified six important factors for future research, like understanding how each nutrient works and choosing the right people to study. This matters because it can improve guidelines for nutrition that help prevent cognitive decline in older adults.
Who this helps: This helps patients and healthcare professionals aiming to improve brain health in aging populations.
Interoceptive differences in elite sprint and long-distance runners: A multidimensional investigation.
2023
PloS one
Seabury T, Benton D, Young HA
Plain English This study looked at how elite sprint and long-distance runners perceive their bodily sensations compared to regular people. It found that sprinters are better at tuning into their internal feelings and managing their emotions than distance runners and non-athletes. However, elite athletes overall showed less emotional awareness than non-athletes. This matters because understanding these differences can help improve training and performance strategies for athletes.
Who this helps: This helps athletes and coaches looking to enhance performance in competitive sports.
Plain English This study looked at how the spike protein of the SARS-CoV-2 virus changes shape and how those changes affect its ability to bind to cells and evade the immune system. Researchers found that spike proteins from the alpha, beta, and delta variants tend to be in an open state, which helps them bind to the ACE2 receptor and promotes viral entry into cells. In contrast, the omicron variant primarily stays in a closed state, which may help it avoid detection by antibodies while still being prepared to enter cells under certain conditions.
Who this helps: This information benefits scientists and public health officials working to understand virus behavior and develop vaccines and treatments.
O-Linked Sialoglycans Modulate the Proteolysis of SARS-CoV-2 Spike and Likely Contribute to the Mutational Trajectory in Variants of Concern.
2023
ACS central science
Gonzalez-Rodriguez E, Zol-Hanlon M, Bineva-Todd G, Marchesi A, Skehel M +17 more
Plain English This study looked at how specific sugar molecules (called O-linked glycans) on the spike protein of the virus that causes COVID-19 affect how the virus matures and mutates. Researchers found that these sugars can alter the virus's ability to be processed by important proteins—specifically, they found that the presence of sialic acid can slow down the processing by up to 65%. Understanding these sugar modifications is important because they can influence how the virus spreads and evolves, especially in concerning variants like Alpha, Delta, and Omicron.
Who this helps: This helps patients by informing strategies to combat COVID-19 variants.
Development of high affinity broadly reactive aptamers for spike protein of multiple SARS-CoV-2 variants.
2023
RSC advances
Le TT, Benton DJ, Wrobel AG, Gamblin SJ
Plain English Researchers created special molecules called aptamers that can effectively target the spike protein of various SARS-CoV-2 variants, including the original Wuhan strain and newer ones like Omicron. These aptamers are very effective, with binding strengths measured in the picomolar range, meaning they work exceptionally well. This is important because it could lead to better treatments and diagnostics for COVID-19 that are effective against all current variants.
Who this helps: Patients and healthcare providers working on COVID-19 treatment and prevention.
Single-wavelength polarization- and mode-division multiplexing free-space optical communication at 689 Gbit/s in strong turbulent channels.
2023
Optics letters
Li Y, Chen Z, Benton DM, Patel M, Lavery MPJ +1 more
Plain English Researchers successfully tested a new optical communication system that can send data super-fast, achieving speeds of 689.2 gigabits per second, even in difficult conditions like strong turbulence. By using advanced technology to handle multiple signals at once, they improved the system's ability to function despite disruptions, reaching a new high of 10 channels operating simultaneously. This breakthrough is important because it opens the door for faster and more reliable data transmission, especially in environments where traditional methods struggle.
Who this helps: This benefits technology companies and telecommunications providers aiming to enhance internet speeds and reliability.
TRIMming away colon cancer: TRIM21-mediated ubiquitination as an activator of the Hippo tumor suppressor pathway.
2023
Cell chemical biology
Benton D, Chernoff J
Plain English Researchers studied how a protein called TRIM21 affects the Hippo pathway, which helps control cancer growth. They found that TRIM21 helps activate a key enzyme (MST2) in this pathway, and when combined with the antidepressant Vilazodone, it boosted this effect, leading to a significant reduction in the spread of colon cancer. This finding is important because it suggests a new potential way to treat or prevent metastasis in colon cancer patients.
Who this helps: Patients with colon cancer.
How do family caregivers of older adults cope with relationship strain?
2023
Aging & mental health
Meyer K, Rath L, Avent E, Benton D, Nash P +1 more
Plain English This study looked at how family caregivers manage the stress that comes from caring for older adults, focusing on the strain in their relationships. Researchers found that caregivers use four main approaches to cope: taking care of themselves, changing their own behaviors, adjusting their feelings, and seeking help. For example, caregivers of people with dementia often focus on adapting their own actions and viewpoints instead of trying to change their loved ones' behavior. This matters because understanding these coping strategies can help improve the support and resources available for caregivers.
Who this helps: This helps family caregivers and support organizations assist them better.
Qualitative Evaluation of Family Caregivers' Experiences Participating in Knowledge and Interpersonal Skills to Develop Exemplary Relationships (KINDER): Web-Based Intervention to Improve Relationship Quality.
2023
JMIR formative research
Meyer K, Gonzalez A, Benton D
Plain English This study looked at a web-based program called KINDER, designed to help family caregivers of people with Alzheimer’s disease or related dementias build better relationships and reduce poor caregiving practices. Out of 23 caregivers who started the program, only 7 completed it, but those who did found the material helpful and meaningful, especially in addressing mistreatment. The researchers learned that while the online format was convenient, many caregivers wanted more chances to connect with each other and faced some challenges with the technology used in the program.
Who this helps: This benefits family caregivers of individuals with Alzheimer's disease or related dementias.
Health practitioner regulation and national health goals.
2023
Bulletin of the World Health Organization
Mahat A, Dhillon IS, Benton DC, Fletcher M, Wafula F
Plain English This study looked at how regulating healthcare workers can improve patient safety and help meet national health goals, such as managing healthcare costs and ensuring that there are enough skilled workers. The research found that while regulations can support these goals, many systems have significant gaps, meaning they don't work as well as they could. The COVID-19 pandemic showed that changes in regulations can allow for more flexibility, which is crucial for achieving better healthcare for everyone.
Who this helps: This helps patients and healthcare systems by ensuring better access to qualified health professionals.
The role of interoception in age-related obesity: A structural equation modelling study.
2023
Appetite
Brennan A, Benton D, Gaylor C, Young HA
Plain English This study looked at how older women’s awareness of their body signals, like hunger and fullness, relates to their body weight. Researchers found that while older women were generally heavier, they were less attentive to their body cues about eating and had lower tendencies towards emotional and food-related overeating. This matters because understanding these patterns can help create better weight management strategies for older adults.
Who this helps: This benefits older women struggling with obesity and health professionals working with them.
Associative learning or Bayesian inference? Revisiting backwards blocking reasoning in adults.
2023
Cognition
Benton DT, Rakison DH
Plain English This study looked at how adults understand cause and effect, particularly a process called backwards blocking reasoning, which involves recognizing that a previously learned cause is less relevant when new information is introduced. The researchers found that adults consistently used backwards blocking reasoning even when distracting information was present, and their judgments matched a Bayesian model of reasoning rather than other models based on associative learning. Understanding how people think about cause and effect is important because it helps improve educational strategies, decision-making, and even therapy approaches.
Who this helps: This helps educators, therapists, and anyone interested in improving critical thinking skills.
RHOA drivers take alternate routes in gastric cancer.
2023
Science signaling
Benton D, Chernoff J
Plain English This study looked at two specific mutations in a gene called RHOA that is often altered in gastric cancer. The researchers found that different RHOA mutations, like Y42C and L57V, lead to varying effects on how cancer cells communicate and grow. This is important because understanding these differences can help develop better treatments for gastric cancer.
Who this helps: Patients with gastric cancer.
Ethical advocacy in the end-of-life nursing care: A concept analysis.
2022
Nursing forum
Hatefimoadab N, Cheraghi MA, Benton DC, Pashaeypoor S
Plain English This study looked at the importance of ethical advocacy in nursing care for patients nearing the end of life. Researchers found that ethical advocacy involves helping patients by following nursing ethics, supporting their rights, and seeking justice in healthcare, while also using the input of hospital ethics committees. Understanding and implementing ethical advocacy is crucial for nurses to ensure that patients receive quality care during a very sensitive time.
Who this helps: This benefits patients facing end-of-life care and their families, as well as the nurses who support them.
Uphill sprinting load- and force-velocity profiling: Assessment and potential applications.
2022
Journal of sports sciences
Delaney JA, McKay BA, Radcliffe J, Benton DT, Samozino P +2 more
Plain English This study looked at how different hill gradients affect sprinting speed in athletes. Researchers tested 24 college athletes on flat ground and hills with slopes of 5.2%, 8.8%, and 17.6%. They found that as the slope increased, athletes' speed decreased by an average of 1.7% for each degree of incline, which suggests that while steeper hills don’t add much resistance for building speed, they can help improve running technique.
Who this helps: This information benefits athletes and coaches focusing on improving sprinting performance.
Judgements of attractiveness of the opposite sex and nostril differences in self-rated mood: The effects of androstenol.
2022
Biological psychology
Beaton AA, Jones L, Benton D, Richards G
Plain English This study explored how a chemical called androstenol affects people's feelings and their judgments of attractiveness towards the opposite sex. Participants who sniffed androstenol found photos of the opposite sex more attractive than those who sniffed a control odor, with a clearer impact felt when androstenol was sniffed through the right nostril. Men felt more energetic and both men and women reported feeling sexier, while sniffing through the left nostril increased feelings of irritability and aggression.
Who this helps: This research benefits psychologists and relationship counselors by enhancing understanding of how scent influences attraction and mood.
Weaker connectivity in resting state networks is associated with disinhibited eating in older adults.
2022
International journal of obesity (2005)
Brennan A, Marstaller L, Burianová H, Benton D, Hanley CJ +2 more
Plain English The study looked at how the brain's connections during rest relate to eating behaviors in younger and older adults. Researchers found that older adults (aged 60-73) had weaker connections in certain brain networks linked to self-control and body awareness, which was associated with less disinhibited eating, meaning they had better control over their eating habits. Understanding these differences helps to identify how aging impacts eating behaviors, which is important for addressing obesity in older adults.
Who this helps: This benefits older adults at risk of obesity and healthcare providers working with them.
Evolution of the SARS-CoV-2 spike protein in the human host.
2022
Nature communications
Wrobel AG, Benton DJ, Roustan C, Borg A, Hussain S +4 more
Plain English This study looked at two variants of the SARS-CoV-2 virus, called Alpha and Beta, focusing on their spike proteins, which help the virus attach to and enter human cells. The researchers found that both variants have a specific mutation (N501Y) that makes it easier for the virus to bind to human cells, leading to increased spread. The Alpha variant spike is particularly stable when it binds to human cells, while the Beta variant has a different mutation (K417N) that also helps improve its ability to attach, making these variants more effective at spreading among humans.
Who this helps: This research benefits public health officials and healthcare providers by improving understanding of how different virus variants behave.
The Living Alone with Cognitive Impairment Project's Policy Advisory Group on Long-Term Services and Supports: Setting a Research Equity Agenda.
2022
International journal of environmental research and public health
Portacolone E, Torres JM, Johnson JK, Benton D, Rapp T +3 more
Plain English The study focused on improving long-term services and support for people living alone with cognitive impairment, aiming to ensure these services are available and fair for all older adults. The advisory group found three key areas needing attention: understanding the unique needs of these individuals, utilizing cognitive impairment diagnoses better, and improving the range and quality of services offered. Addressing these areas is crucial for shaping policies that ensure equitable treatment for those affected.
Who this helps: This helps older adults with cognitive impairment and their caregivers.
Demonstration of 10-channel mode- and polarization-division multiplexed free-space optical transmission with successive interference cancellation DSP.
2022
Optics letters
Li Y, Hu Z, Benton DM, Ali A, Patel M +1 more
Plain English This study looked at a new way to transmit data using light through the air, successfully testing a system that can handle 10 different data channels at once. They discovered that using a special digital processing technique helped reduce unwanted signal interference between these channels, making the system more efficient. Specifically, they achieved a record of 10 independent channels and a high data transfer efficiency of 13.7 bits per second per Hertz, which is a significant improvement over previous systems.
Who this helps: This benefits data communication companies and researchers working to improve wireless data transmission technologies.
Single-wavelength transmission at 1.1-Tbit/s net data rate over a multi-modal free-space optical link using commercial devices.
2022
Optics letters
Hu Z, Li Y, Benton DM, Ali AAI, Patel M +1 more
Plain English This study looked at a new way to send a lot of data quickly through the air using special optical technology, achieving a record speed of 1.1 terabits per second. The researchers designed a system that can handle multiple separate data streams at once, making it more efficient than previous methods. This advancement is important because it paves the way for faster internet and communication technologies without needing specialized hardware.
Who this helps: This benefits technology companies and internet service providers looking to improve data transmission speeds.
The impact of glycaemic load on cognitive performance: A meta-analysis and guiding principles for future research.
2022
Neuroscience and biobehavioral reviews
Gaylor CM, Benton D, Brennan A, Young HA
Plain English This study examined how the glycaemic load (GL) of breakfast affects cognitive performance. Researchers analyzed 15 studies and found that while GL did not impact cognition in the first 119 minutes after eating, a low-GL breakfast led to better memory scores after 120 minutes, especially in younger adults and those with better glucose tolerance. This is important because improving memory can enhance learning and performance for individuals, particularly young adults.
Who this helps: This benefits patients, especially young adults and children.
Mediterranean diet, interoception and mental health: Is it time to look beyond the 'Gut-brain axis'?
2022
Physiology & behavior
Young HA, Freegard G, Benton D
Plain English This study looked at how following a Mediterranean diet, which is rich in fruits, vegetables, fish, and whole grains, affects how well people can sense their heartbeats and understand their own bodily functions. The researchers found that people who adhered to this diet had better accuracy in detecting their heartbeats and were more aware of their own errors in those tasks. This is important because it shows that diet may play a larger role in mental health and bodily awareness than previously thought.
Who this helps: This helps patients and mental health professionals looking to improve psychological well-being through dietary changes.
Carbohydrate and sleep: An evaluation of putative mechanisms.
2022
Frontiers in nutrition
Benton D, Bloxham A, Gaylor C, Brennan A, Young HA
Plain English This research looked at how carbohydrates in our diet might affect sleep. It found that eating less carbohydrate can lead to more time spent in restorative slow-wave sleep while reducing rapid-eye-movement sleep. Despite some ideas suggesting that carbs help sleep by increasing brain chemicals like serotonin, the study concluded that low-carb diets can actually help improve sleep quality more effectively than high-carb diets.
Who this helps: This helps patients struggling with sleep issues.
Publisher Correction: Individual differences in sensory and expectation driven interoceptive processes: a novel paradigm with implications for alexithymia, disordered eating and obesity.