Elina Mattila

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This study looked at how effective nursing interventions are for adults in hospitals by reviewing existing research. Out of thousands of articles, 11 reviews that included 141 original studies were analyzed. The findings showed that nursing interventions can reduce anxiety, pain, and the length of hospital stays, but there's not enough strong evidence about their effectiveness overall, highlighting a need for better quality studies and more focus on simple preventive measures that work well. Who this helps: This benefits patients in hospitals who receive nursing care.

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This study looked at how different personal backgrounds and well-being levels affect people's use of a mobile app designed to promote healthy living. Out of 1,646 people surveyed, 863 started using the app. It found that men, unemployed individuals, and those with higher life satisfaction were less likely to begin using the app, while certain groups, like retirees or those with high alcohol consumption, were more likely to fit into categories of struggling non-active users. Who this helps: This research benefits developers of health apps, helping them create better tools for those who need support with their lifestyle and mental health.

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This study explored how good leadership influences nurses' sense of independence and involvement in their work, examining over 4,000 nurses from 9 hospitals outside the United States. The findings revealed that only 9% of these nurses felt engaged in their roles, while 34% were disengaged; nurses reported that having responsive managers and being involved in decision-making increased their engagement. This research matters because improving leadership can lead to more engaged nurses, which can enhance patient care and workplace satisfaction. Who this helps: This benefits nurses and healthcare organizations.

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This study looked at how effective different types of lifestyle programs are at reducing the risk of type 2 diabetes in nearly 3,000 adults. Participants who used a combination of digital tools and group meetings (DIGI+GROUP) showed a significant improvement in diet quality, scoring 3.2 points higher on a diet quality index compared to the usual care group, while their waist size decreased by an average of 1.8 cm. This is important because better diet and weight management can help prevent type 2 diabetes and improve overall health. Who this helps: Patients at risk for type 2 diabetes.

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This study looked at the experiences of nursing managers during the COVID-19 pandemic by analyzing 14 relevant articles published over two years. It found that nursing managers faced challenges in adapting to new roles, ensuring staff well-being, and managing communication as the situation changed frequently. Understanding these experiences is important for improving support and preparation for future health crises. Who this helps: This helps nursing managers and healthcare organizations prepare for future emergencies.

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This study looked at how using the BitHabit app, designed to help people change their habits, affected factors related to Type 2 diabetes in nearly 1,000 people at risk for the disease over a year. Researchers found that those who used the app more often saw improvements in their diet quality, while changes in body measurements like waist size and body mass index were only weakly linked to app usage. This is important because better diet can help prevent or delay Type 2 diabetes. Who this helps: This helps patients at risk for Type 2 diabetes by providing a useful tool for improving their lifestyle.

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This study examined whether a single fecal microbiota transplant (FMT) could help patients with ulcerative colitis (UC) stay in remission. Out of 24 patients who received FMT, 54% maintained remission, compared to 41% in the placebo group after 12 months. However, the FMT group reported a decline in quality of life compared to the placebo group, and there were no differences in disease relapses or other health measures between the groups. Who this helps: This research informs doctors and patients about the effectiveness of FMT for maintaining remission in ulcerative colitis.

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This study looked at how different nursing roles—generalist, specialist, and advanced practice nurses—operate in hospitals in Finland. Researchers surveyed nearly 1,500 nurses and found that while nurses frequently engage in patient care and education, they are less involved in research, publication, and leadership activities. This matters because clearly defining nursing roles can lead to better management of nursing staff and a more effective healthcare system. Who this helps: This helps nurses and healthcare organizations by clarifying roles and improving career development opportunities.

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This study looked at how people experienced the NoHoW web-based toolkit designed to help maintain weight loss over a year. Researchers found that while users generally liked features like weekly emails and goal-setting tools, their usage and satisfaction declined over time, with only modest acceptance throughout the trial. Improving the toolkit's technical quality and user guidance could enhance its effectiveness, similar to how popular apps are updated regularly. Who this helps: This helps patients trying to maintain their weight loss.

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This study looked at how people used the BitHabit app, which helps form healthy habits to prevent type 2 diabetes, over a year. Out of almost 2,000 participants, about 53% continued using the app for the full year. Those who used the app daily saw the most improvement, such as a better diet and lower body weight. Who this helps: This research benefits patients at risk for type 2 diabetes by offering insights on how to stay engaged with health apps.

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This study looked at how two online modules, one for setting physical activity goals and another for planning ways to overcome obstacles, influenced people's physical activity levels. Out of 811 participants, those who completed the barriers module showed an increase in active minutes, going from an average of about 45 minutes to 47 minutes right after using the module, and this effect lasted for several weeks. This matters because it shows that addressing barriers can help people become more active, which is important for maintaining weight loss. Who this helps: Patients trying to maintain weight loss and increase their physical activity.

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This study looked at how hospital management can support staff's mental well-being during the COVID-19 pandemic. They surveyed nearly 2,000 healthcare workers and found that those who felt supported by their managers had lower anxiety levels. Specifically, staff who received encouragement and had chances to discuss their COVID-19 concerns reported feeling better overall. This is important because it shows that strong management can significantly affect staff mental health, especially in high-stress situations like a pandemic. Who this helps: This benefits hospital staff by improving their mental well-being through effective management.

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This study focused on creating clear guidelines for managing stool banks, which are essential for faecal microbiota transplantation—a treatment mainly used for patients with recurrent Clostridioides difficile infections. The researchers developed a detailed document outlining how to collect, handle, and store donor stool, ensuring that procedures meet safety standards. Implementing these guidelines will help guarantee the quality and availability of donor stool for treatments, which is crucial for improving patient care. Who this helps: Patients suffering from recurring gastrointestinal infections.

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This study looked at the anxiety levels of hospital staff in Finland during the COVID-19 pandemic. It found that while 55% of workers had normal anxiety levels, 30% experienced mild anxiety, 10% had moderate anxiety, and 5% faced severe anxiety. The research highlighted that younger workers and those in university hospitals were especially affected and that stress wasn't only due to direct contact with COVID-19 patients but also related to work dynamics and concerns about infection. Who this helps: This research benefits hospital workers and healthcare administrators by highlighting the need for targeted support and mental health resources.

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This study focused on preventing type 2 diabetes among Somalis in Finland, particularly women who are at higher risk. Researchers created a lifestyle intervention that included group and digital counseling over 12 weeks, with 24 out of 33 people (73%) at risk agreeing to take part. Following the program, participants significantly increased their vegetable intake, and while there was a slight increase in physical activity, it wasn’t statistically significant. Who this helps: This helps Somali women at risk of developing type 2 diabetes.

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The NoHoW Project studied how Europeans attempt to lose weight and keep it off, finding that effective tools for maintaining weight loss are limited. The researchers created a digital toolkit focusing on self-management and emotional regulation for those who lost at least 5% of their body weight in the past year. After testing this toolkit, they aim to improve resources for long-term weight maintenance, helping to prevent weight regain. Who this helps: This benefits individuals trying to maintain their weight loss, as well as healthcare providers looking for effective support tools.

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This study looked at blood infections in cancer patients in Finland from 2006 to 2016. Researchers found that out of 2,296 patients with blood cancers, 3,404 infections occurred, primarily from bacteria. The overall risk of death from these infections was relatively low, with 5.2% of patients dying within a week and 11.4% within 28 days, but it was higher for infections caused by Candida fungi. Overall, these findings highlight the changing patterns of infections over time and underscore the need for ongoing monitoring in vulnerable patient groups. Who this helps: This information benefits doctors and healthcare providers caring for cancer patients.

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This study looked at patients in Finland who had fungal infections related to taking a specific probiotic supplement called Saccharomyces boulardii between 2009 and 2018. Of the 46 patients with a serious bloodstream infection (fungemia), 20 (43%) were using this probiotic, significantly higher than those who had other types of infections. This research highlights the potential risks of using this probiotic, especially in patients who may be vulnerable to fungal infections. Who this helps: This helps doctors and healthcare providers understand the risks of probiotics for their patients.

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This study focused on creating and testing a digital program called the NoHoW Toolkit designed to help people maintain their weight loss over the long term. After researching and developing this toolkit, the researchers found that it included 34 sessions across different modules, utilizing features like videos and tracking tools for weight, activity, and mood. Importantly, users had access to 15 different modules that emphasized motivation and emotional support, which could greatly improve their chances of not just losing weight but keeping it off. Who this helps: This benefits adults struggling with overweight or obesity who have recently lost weight and want to maintain their progress.

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This research paper focuses on how to treat Clostridioides difficile infection (CDI), which often causes diarrhea in patients, especially those who are elderly or have weakened immune systems. The study found that the best treatments for CDI are vancomycin and fidaxomicin, while metronidazole should only be used in mild cases. For patients with recurrent CDI, adding a treatment called bezlotoxumab can help, and fecal microbiota transplantation (FMT) is recommended for those who get CDI repeatedly. Who this helps: This information benefits patients with CDI, particularly those at higher risk for recurrence.

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This study looked at whether fecal microbiota transplantation (FMT) could help people with irritable bowel syndrome (IBS). Out of 49 patients, those who received FMT showed a brief decrease in their IBS symptoms after 12 weeks, but the overall results didn’t meet the goal of lasting relief. The treatment changed the gut bacteria of the patients, but it’s clear that a single FMT treatment isn't a viable option for managing IBS. Who this helps: This helps doctors and patients understand the limitations of FMT for IBS treatment.

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This study looked at how well a type of beneficial bacteria from donor stools can take up residence in patients who receive fecal microbiota transplants (FMT) to treat recurrent infections. Researchers found that specific strains of bifidobacteria from two donors successfully colonized 13 patients for at least one year after their treatment. This is important because it shows that FMT can lead to long-lasting changes in a patient's gut health, which could improve their overall well-being. Who this helps: Patients with recurrent infections who may benefit from fecal microbiota transplants.

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This study looked at an online program designed to help people at risk for type 2 diabetes adopt healthier habits. Out of 3,271 people who signed up, 2,909 were eligible, and 99.5% logged into the app at least once during the first six months. The program shows promise as it engaged a large number of users—over 93% were active in the first week and more than 50% were still active after six months—but it's still unclear if these habits will lead to lasting lifestyle changes. Who this helps: This helps individuals at risk for type 2 diabetes, particularly older adults.

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This study looked at a protein called SHARPIN and how it affects the behavior of cells, especially in tumors. Researchers found that mice lacking SHARPIN had significantly higher levels of a specific imaging marker in their tumors, indicating increased activity of integrins, which help cells stick to each other—this was observed using a special imaging technique called PET. Specifically, the SHARPIN-deficient mice showed much greater marker uptake in tumors compared to normal mice, highlighting SHARPIN's role in controlling tumor growth and blood vessel formation. Who this helps: This research benefits cancer patients and doctors by improving understanding of tumor behavior and potential treatment targets.

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This study looked at how well bezlotoxumab works to prevent repeat infections of Clostridium difficile (CDI) in 46 patients at five university hospitals in Finland. They found that 73% of patients stayed infection-free for at least three months after treatment, and this was still effective in 71% of patients with weakened immune systems; for those with severe CDI, bezlotoxumab prevented recurrences in 63% of cases. This is important because it offers a potential solution for high-risk patients, especially those who might have needed more invasive treatments, like fecal microbiota transplantation, but were able to avoid it. Who this helps: This benefits patients with Clostridium difficile infections and their doctors by providing a viable treatment option.

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The NoHoW study investigated how a digital toolkit could help people maintain weight loss after they had already lost at least 5% of their body weight. A total of 1,627 participants were involved, and the researchers tested different approaches, including self-monitoring, motivation strategies, and emotional support. Initial findings will track weight changes and health improvements over 12 months, which is important for preventing obesity-related diseases and easing the burden on healthcare systems. Who this helps: This research benefits individuals who are trying to maintain their weight loss, healthcare providers, and the broader community by promoting better health outcomes.

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This study looked at a web service created to help entrepreneurs manage their stress positively. After 22 entrepreneurs used the service for six weeks, researchers found that participants' negative stress levels dropped while their positive stress experiences increased. Although the service was used less than expected—only about three days and 101 minutes on average—users found it helpful and appreciated certain features like offline exercises and peer quotes. Who this helps: This benefits entrepreneurs and others in similar stressful jobs.

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This study looked at how taking broad-spectrum antibiotics before a fecal transplant affects the acceptance of new bacteria in the gut. Researchers found that while antibiotics wiped out many of the recipient mice's original gut bacteria, they did not significantly improve how well the new bacteria from the donor were accepted—instead, it only helped a few specific types of bacteria establish themselves. This matters because understanding how to optimize fecal transplants could lead to better treatments for patients with gut-related health problems. Who this helps: Patients with recurrent intestinal infections and other gut-related diseases.

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This study looked at how engaged healthcare workers are in five university hospitals in Finland, focusing on a total of 561 nurses, doctors, and administrative staff. The results showed that, on average, workers rated their engagement at 5.0 out of 6, with the most engaged being administrative staff and higher engagement levels found among women and older workers. This is important because it highlights that healthcare professionals are generally committed to their work, which could lead to better patient care, but it's essential to also address the specific needs of younger workers to keep them engaged. Who this helps: This helps healthcare workers, hospital administrators, and ultimately, patients receiving care.

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Researchers studied an outbreak of the bacteria Serratia marcescens in a neonatal intensive care unit in Finland, where seven premature babies tested positive for the infection within three weeks. Two of these infants developed serious infections, and one sadly died despite treatment. The hospital swiftly implemented hygiene measures like improved handwashing and cleaning, which successfully stopped the outbreak from spreading. Who this helps: This benefits newborn patients in intensive care, their families, and hospital staff.

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This study looked at the long-term effects of fecal microbiota transplantation (FMT) in patients with repeated Clostridium difficile infections, tracking 84 patients over an average of 3.8 years. It found that those who received FMT experienced faster and more significant improvements in their bowel habits and mental health compared to those treated with antibiotics, without increased risk of serious diseases like cancer or autoimmune disorders. This is important because it confirms that FMT is not only safe in the long run but also more effective than antibiotics for managing symptoms and overall health. Who this helps: This helps patients with recurrent Clostridium difficile infections who are seeking better treatment options.

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This study developed a new online tool that allows people to create personalized health profiles based on their own health data. It helps individuals understand their health behaviors and needs, giving feedback that was found to be interesting and easy to use for 29 participants. This tool is important because it empowers users to take control of their health and assists doctors in providing tailored care. Who this helps: This benefits patients looking to improve their health management and healthcare providers aiming for personalized treatment solutions.

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This study examined how viruses, specifically bacteriophages, behave after fecal microbiota transplants (FMT) in patients with recurring Clostridium difficile infections. Researchers found that the viruses from the donors were present in the patients for up to 12 months, but the way each patient's body accepted these viruses varied significantly depending on their specific donor. This understanding is important because it highlights the role of viruses in maintaining gut health after FMT, which could improve treatment strategies. Who this helps: Patients undergoing fecal microbiota transplantation for Clostridium difficile infections.

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This study investigated the role of a protein called SHARPIN in the development of mammary glands in mice. Researchers found that mice without SHARPIN had less growth of mammary ducts during puberty, and their surrounding tissue had improperly arranged collagen and reduced stiffness. This matters because understanding how SHARPIN helps form healthy mammary tissue could give insights into breast development and potential issues related to breast health. Who this helps: This helps researchers and healthcare professionals working on breast health and developmental biology.

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This study looked at how acceptance and commitment therapy (ACT) helps people adopt intuitive eating habits and manage their weight. Researchers found that 219 overweight or obese participants who underwent ACT, either in a group or individually through a mobile app, showed improvements in their body mass index (BMI) and intuitive eating skills. Specifically, people became better at eating based on their physical needs rather than emotions, thanks to increased psychological flexibility, which is the ability to stay connected to meaningful activities despite negative feelings about weight. Who this helps: This helps overweight or obese individuals looking to improve their eating habits and manage their weight.

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Researchers focused on a condition called common variable immunodeficiency (CVID) in Southern Finland, finding that it affects about 6.9 out of every 100,000 adults. This study identified 132 patients, revealing that many experience multiple health issues and that 73% of them show more than one type of symptoms. This is important because the high prevalence could be linked to genetic factors in the Finnish population, which may help in understanding and diagnosing the condition better. Who this helps: This helps patients with CVID and their doctors by improving awareness and care options.

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This study looked at how well fecal microbiota transplantation (FMT) works for patients with recurring infections caused by harmful bacteria (rCDI) and those with other health issues, including serious illnesses. Out of 13 patients with rCDI who received FMT, 11 were successfully treated, and there were no serious side effects. The research also showed that FMT could help eliminate some antibiotic-resistant bacteria and reduce symptoms for certain other conditions, although it didn't work for everyone. Who this helps: This helps patients with recurring infections, especially those with weakened immune systems, as well as patients facing antibiotic resistance.

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This study brought together 28 experts from 10 countries to create guidelines for using faecal microbiota transplantation (FMT) in treating infections and other gut-related disorders. They found that FMT is a promising treatment but requires standardized procedures for safety and effectiveness. Their recommendations aim to help doctors implement FMT more widely and effectively, ensuring that the treatment is both safe and regulated. Who this helps: This helps patients suffering from infections and gut-related disorders.

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This study looked at how people used a mobile app based on Acceptance and Commitment Therapy (ACT) over eight weeks to improve their mental flexibility. Out of 74 participants, most were women, and they engaged with the app an average of 21 times over about 4.7 hours total. The more frequently and intensely they used the app, the greater the improvement seen in their psychological flexibility, with significant benefits noted for those who used certain types of exercises. Who this helps: This helps patients dealing with psychological stress, especially women and older adults.

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This study looked at how a treatment called faecal microbiota transplantation (FMT) affects the gut bacteria of patients with recurring Clostridium difficile infections. Researchers found that FMT successfully restored healthy gut bacteria in all 14 patients, with a significant increase in two beneficial bacteria groups and a lasting similarity between the patients' gut bacteria and those of the donors for at least a year. This is important because it highlights how FMT can create lasting changes in gut health, potentially leading to new treatments for other gut-related diseases. Who this helps: This helps patients suffering from recurrent Clostridium difficile infections.

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This research examined how well frozen stool samples work compared to fresh stool samples in treating patients with recurrent Clostridium difficile infections. The study found that at 12 weeks after treatment, 96% of patients who received frozen fecal transplants had their symptoms resolved. Overall, both frozen and fresh stool transplants showed an 88% success rate when followed for a year, and there were minimal side effects. Who this helps: This benefits patients suffering from recurrent Clostridium difficile infections by providing a more practical treatment option.

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This study looked at how specific proteins, vimentin and ERK, work together to control the Slug gene's role in helping cancer cells become more mobile and spread in the body. Researchers found that when vimentin and ERK were blocked in cancer cells, their ability to move and invade new areas was significantly reduced, by over 60%. Understanding this process is important because it could lead to new strategies for stopping cancer spread, especially in aggressive forms like triple-negative breast cancer. Who this helps: This helps cancer patients, especially those with triple-negative breast cancer, by potentially leading to new treatments that prevent tumor spread.

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This study looked at how different lifestyle programs can help people with obesity and stress. Researchers involved 339 participants who were divided into four groups: one used a web-based therapy, another used a mobile app for mindfulness, a third attended in-person mindfulness sessions, and the last group received no intervention. They measured changes in psychological well-being, lifestyle habits, and physical health over time to see which methods were most effective. Who this helps: This benefits patients dealing with obesity and psychological stress.

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This study looked at how fecal microbiota transplantation (FMT) helps a man with colitis caused by antibiotics, which is not due to a specific infection. The patient had his symptoms resolved and normal gut function restored after the FMT, and tests showed that beneficial bacteria in his gut increased and stabilized over the next 14 months. This is important because it shows that FMT can effectively treat gut issues related to antibiotic use by restoring healthy gut bacteria. Who this helps: This helps patients suffering from antibiotic-related gut problems.