Gabriele Riegler

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This study looked at ultrasound images of patients who had surgery for carpal tunnel syndrome but still had symptoms because the transverse carpal ligament wasn't fully cut. They found that in 46 patients, the part of the ligament that remained uncut was about 6.7 mm long. In fact, more than half of these patients reported that their symptoms were worse after surgery, highlighting the importance of fully addressing this issue during surgery. Who this helps: This helps patients who have undergone carpal tunnel surgery and are still experiencing symptoms.

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This study looks at how the median nerve appears on ultrasound, showing what healthy nerve images should look like. It includes detailed pictures and explanations of the nerve’s usual anatomy, as well as different variations to help prevent misunderstandings in readings. The findings are important because they provide clear guidelines for medical professionals on what to expect when scanning the median nerve. Who this helps: This benefits doctors and radiologists who perform and interpret ultrasound examinations.

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This research paper looks at how ultrasound scans show the normal structure of the ulnar nerve and its main branches in the arm. The study provides detailed images that help doctors understand what a healthy ulnar nerve looks like using advanced ultrasound technology. This is important because it helps in diagnosing nerve problems more accurately. Who this helps: This benefits doctors who treat patients with nerve conditions.

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This study looked at how anemia affects people with inflammatory bowel disease (IBD) and found that 13.6% of those patients had anemia, primarily due to iron deficiency. Over 24 weeks, patients' hemoglobin levels improved from an average of 108 g/L to 121 g/L, especially when they received iron supplements, but the majority remained anemic throughout the study. Anemia significantly worsened patients' fatigue and quality of life, indicating it’s a persistent challenge for many with IBD. Who this helps: This helps patients with IBD who suffer from anemia and their doctors in managing their treatment.

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This study examined how the ulnar nerve and its branches appear on ultrasound when there are problems or diseases affecting them. The researchers used advanced ultrasound technology to gather clear images from various medical cases, showing different pathological findings. Understanding these ultrasound images is crucial because it helps doctors better diagnose and treat conditions related to the ulnar nerve. Who this helps: This helps doctors and medical professionals who treat patients with ulnar nerve issues.

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This study looked at rare variations of the ulnar nerve, specifically a loop around a muscle in the arm, using ultrasound. Researchers found this unusual nerve loop in six cases involving five patients from 2019 to 2023. In three of these cases, the loop was linked to symptoms, and they noticed that the affected nerve branch was larger than normal. Understanding these variations is important because they could be misdiagnosed and help explain certain arm symptoms. Who this helps: This helps patients experiencing unexplained arm symptoms and their doctors in diagnosing nerve issues more accurately.

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This study looked at anemia in patients with inflammatory bowel disease (IBD) across 28 hospitals in Italy. Out of 5,416 patients, 737 (about 14%) were found to be anemic, predominantly due to iron deficiency. The research highlights that severe anemia worsens fatigue and quality of life, yet many patients—69% with iron deficiency and 35% with vitamin deficiencies—are not receiving the necessary treatment. Who this helps: This information benefits patients with IBD and their doctors by highlighting the importance of properly managing anemia.

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This paper examines how ultrasound can help identify issues with the lateral femoral cutaneous nerve, which can cause a condition called meralgia paresthetica (MP). The authors reviewed various cases and found specific ultrasound patterns that indicate MP, helping to recognize and diagnose the problem. They also shared their experience using ultrasound to guide treatments, which is important for effectively addressing this nerve condition. Who this helps: This helps patients suffering from meralgia paresthetica and their doctors.

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This study looked at how ultrasound can help doctors see if the radial nerve is being compressed during surgery. It found that using ultrasound makes it easier to identify problems with this nerve caused by tight sutures. This is important because knowing the condition of the radial nerve during surgery can lead to better outcomes for patients. Who this helps: This helps patients undergoing surgery where the radial nerve might be at risk.

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This study looked at how colorectal cancer (CRC) affects people with Inflammatory Bowel Disease (IBD). Researchers found that 25% of IBD patients diagnosed with CRC were under 40 years old, and over half of these patients showed CRC-related symptoms. The findings highlight the importance of closely monitoring certain groups of IBD patients, as those with ulcerative colitis had a higher detection rate of CRC through colonoscopy and faced significant risks of cancer-related death. Who this helps: This research benefits patients with IBD, particularly those at higher risk for developing colorectal cancer.

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This study explored how well specific nerves in the front and inner part of the lower leg send feeling signals by using targeted nerve blocks on 14 healthy people. It found that the areas affected by these nerves varied quite a bit, with average sizes of 258.58 mm for one nerve, 193.26 mm for another, and 166.78 mm for a third, and some overlapping areas were also identified. Understanding these nerve fields is important for doctors to better diagnose and treat conditions affecting sensation in the lower leg. Who this helps: This helps doctors and healthcare providers in treating patients with nerve-related conditions.

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This study focused on using ultrasound to examine the deep peroneal nerve (DPN), a nerve in the leg that can be affected by various conditions. The researchers showed how to identify the normal structure of the DPN and described several disorders that can impact it. This is important because clear imaging can help diagnose nerve-related issues more effectively. Who this helps: This benefits patients suffering from leg nerve problems and the doctors treating them.

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This research paper looks at how ultrasound images can show both healthy and unhealthy conditions of the radial nerve, which is located in the arm. It provides examples of various cases, helping to clarify what normal and abnormal appearances look like on the ultrasound. This information is important because it helps doctors diagnose issues related to the radial nerve more accurately. Who this helps: This helps doctors who perform ultrasound exams on patients with arm-related nerve problems.

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This research focused on creating a new genetic test to identify variations in the lactase gene, which determines whether adults can digest lactose in milk. The scientists developed a method that enables them to quickly detect eight specific genetic variations linked to lactase persistence at once, which makes testing more efficient. This advancement is important because it can help better understand lactose tolerance in different populations and improve dietary guidance. Who this helps: This helps patients who are lactose intolerant or have dietary concerns related to lactose.

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This study looked at cancer risk in patients with inflammatory bowel disease (IBD) over six years, involving 1,209 patients, of whom 403 developed cancer. The findings revealed that cancer was most common in the digestive system, affecting 32% of those with cancer, with specific types differing by IBD type; colorectal cancer was more common in ulcerative colitis patients (29%) than in those with Crohn's disease (17%). Certain conditions, like severe Crohn's disease or extensive ulcerative colitis, significantly increased the risk of developing cancer. Who this helps: This information benefits patients with inflammatory bowel disease and their doctors by identifying key risk factors for cancer.

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This study looked at how effective and safe the drug golimumab is for patients with ulcerative colitis, a condition that causes inflammation in the colon. Out of 196 patients treated, 66.3% felt better after three months, with a significant drop in markers of inflammation. However, only 39.3% of those who improved continued to see benefits after a year. The findings are important because they help identify which patients are more likely to benefit from this treatment and confirm that golimumab can be safely used in real-life situations. Who this helps: This research benefits patients with ulcerative colitis and their doctors by guiding treatment decisions.

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This study looked at using high-resolution ultrasound to visualize and assess the transverse cervical nerve (TCN), which provides sensation to the skin in the neck and can be damaged during surgery. Researchers found that the TCN could be clearly seen in all examined people and specimens, with a 100% success rate in confirming what was seen through ultrasound with actual dissections. In healthy volunteers, the average distance between the TCN and another nerve was about 10.4 mm, indicating good potential for accurate assessment. This study matters because better visualization of the TCN can help prevent pain after neck surgeries and improve patient care. Who this helps: This helps patients undergoing neck surgery and their doctors.

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The SOLE study examined 552 Italian patients with active Crohn's disease to understand their health issues, concerns, and how well they manage their treatment. It found that many patients worried about having an ostomy bag or needing surgery, and these worries were linked to worse disease activity and lower treatment adherence. Additionally, patients taking anti-TNF-α medications reported better treatment satisfaction and were more able to carry out daily activities. Who this helps: This research benefits patients with Crohn's disease and their healthcare providers.

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The study looked at how well two tests for lactose intolerance - a breath test and a genetic test - matched up in adults who showed symptoms after eating dairy. The results showed that the tests agreed 88.6% of the time, which means they are reliable. This matters because understanding lactose intolerance better can lead to more accurate diagnoses and better management of symptoms for patients. Who this helps: Patients suffering from lactose intolerance.

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This study looked at how to better see and diagnose two specific thigh nerves—the intermediate femoral cutaneous nerve and the medial femoral cutaneous nerve—using high-resolution ultrasound. Researchers were able to successfully identify these nerves in 16 donated limbs and in 12 patients with nerve issues from previous surgeries, achieving a 100% success rate for locating them in cadavers and a high success rate in patients. This matters because it improves the ability to diagnose nerve damage, which can lead to effective treatments that relieve pain and improve patient outcomes. Who this helps: This helps patients who may experience nerve damage after thigh surgery.

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This study looked at how well high-resolution ultrasound can identify a specific nerve branch in the knee, known as the infrapatellar nerve branch. Researchers found that ultrasound could accurately locate these nerve branches in 86% to 100% of cases and confirmed that the branches followed a highly variable path in different individuals. This finding is important because being able to visualize these nerve branches can improve diagnosis and treatment for patients experiencing knee pain. Who this helps: This benefits patients with knee pain and doctors treating them.

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This study looked at whether high-resolution ultrasound can help visualize Pacinian corpuscles, which are small structures in the skin that detect pressure and vibration. Researchers successfully used ultrasound to find these structures in the palms of two cadaver hands and measured them in healthy volunteers, finding that the average size of the Pacinian corpuscles was 1.40 mm. This is important because it improves our understanding of how these sensory structures can be seen in medical imaging, which may help diagnose conditions related to them. Who this helps: This benefits doctors and patients by providing better tools for diagnosing skin and nerve issues.

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This study looked into non-celiac gluten sensitivity (NCGS), which affects people who experience gastrointestinal and other symptoms when they consume gluten but do not have celiac disease or a wheat allergy. Researchers found that the exact number of individuals with NCGS is unclear and that it may include various subgroups with different causes and symptoms. This matters because better understanding of NCGS could lead to improved diagnosis and treatment options, as current research is hindered by vague criteria and a lack of specific tests. Who this helps: This benefits patients suffering from gluten-related symptoms and healthcare providers looking to offer accurate diagnoses.

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This study looked at how well high-resolution ultrasound can show a specific part of the median nerve, called the recurrent motor branch (RMB). The researchers were able to clearly see and measure the RMB in both cadaver hands and 20 healthy volunteers, finding an average diameter of 0.7 mm. They also identified three patients with issues in their RMB, indicating that this ultrasound technique can help doctors see nerve problems more clearly and tailor treatments more effectively. Who this helps: This benefits patients suspected of having nerve injuries and their doctors.

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This study examined the safety of various treatments for inflammatory bowel diseases (IBD), particularly Crohn's disease and ulcerative colitis, in Italy. The Italian Group for the Study of Inflammatory Bowel Disease created guidelines that evaluate the safety and effectiveness of different medications, such as aminosalicylates and TNF-alpha antagonists. These guidelines are important because they provide tailored recommendations based on local healthcare conditions and costs, which can improve patient care. Who this helps: This helps patients with inflammatory bowel diseases and their doctors.

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This study focused on using high-resolution ultrasound to visualize the deep branch of the ulnar nerve throughout its entire length. The researchers found that the nerve was clearly visible in all tested cases, including in 8 cadaver hands and 20 healthy volunteers, with an average size of about 1.8 mm at one point and 1.6 mm at another. Understanding how to successfully image this nerve is important because it can help diagnose and treat nerve-related conditions more effectively. Who this helps: This benefits doctors and medical professionals involved in diagnosing ulnar nerve conditions.

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This study looked at how different PET scan techniques affect the detection of lung tumors in 37 cancer patients. It found that using a specific advanced reconstruction method (PSF-based) and a larger image matrix significantly improved the ability to spot tumor lesions, with detection rates of 94.2% for the best method compared to only 67.8% for the standard method. These findings matter because they help ensure that lung cancer is diagnosed more accurately, which can lead to better treatment decisions. Who this helps: Patients with lung cancer.

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This study looked at a special imaging technique called Virtual Chromoendoscopic Magnification (VCM) to identify different types of blood vessel patterns in mouth lesions. Researchers assessed 31 people with oral lesions and found that the most concerning pattern, called IPCL type IV, was linked to cancer in 4 out of 6 cases. The results were promising, showing high accuracy—100% sensitivity and 100% negative predictive value—suggesting this method could effectively help in diagnosing oral cancers. Who this helps: This benefits patients with oral lesions and doctors diagnosing oral cancer.

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This study looked at how type 1 diabetes affects the cartilage and tendons in the knees of patients compared to healthy individuals. It found that patients with type 1 diabetes had lower sodium levels in their knee cartilage and higher sodium levels in their patellar tendons compared to healthy volunteers, with specific reductions of about 8% in cartilage and increases of around 25% in tendons. These changes may indicate early biochemical issues related to diabetes that aren't visible through standard imaging. Who this helps: This study benefits patients with type 1 diabetes and their doctors by highlighting early signs of potential knee problems.

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Researchers studied anaemia in patients with inflammatory bowel diseases (IBD) to understand how common it is and what causes it. They found that anaemia affects 14% of IBD patients, especially those with active disease or in the hospital, with rates of 26% in hospitalized patients compared to 11.7% in out-patients. Iron deficiency was the main reason for anaemia, affecting over half of the patients who had it. Who this helps: This information benefits patients with IBD and their doctors by highlighting the importance of monitoring and treating anaemia.

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This study looked at how patients with Inflammatory Bowel Diseases (IBD) are affected by rare gastrointestinal cancers called GIST and carcinoid tumors. The researchers found that while there isn't a higher risk of GIST in IBD patients, those with Crohn's disease might be more likely to develop carcinoid tumors. This matters because understanding these risks and how they differ from other cancer types can help doctors make better decisions about monitoring and treating IBD patients. Who this helps: This helps patients with IBD and their doctors by improving cancer awareness and treatment strategies.

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This research paper looks at how using imaging techniques for bones and muscles can help prevent injuries and health issues. It found that these imaging methods can monitor bone health, detect problems that might lead to injuries, and improve the way doctors communicate findings. The study highlights that many fractures in patients with weakened bones, like those with osteoporosis, are often missed, which can lead to serious health problems. Who this helps: This helps patients with osteoporosis and healthcare providers managing their care.

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This study looked at how well two imaging methods, 3D-Endoanal Ultrasound (3D-EAUS) and MRI, help doctors find and assess anal fistulas in patients with Crohn's disease. Researchers tested 51 patients and found that while both methods are useful, 3D-EAUS was better at identifying intersphincteric fistulas, while MRI was more effective for suprasphincteric and extrasphincteric fistulas. The findings are important because they help doctors choose the right imaging technique for better diagnosis and treatment planning. Who this helps: This helps patients with Crohn's disease who have anal fistulas.

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This study looked at the risk of cancer in patients with inflammatory bowel disease (IBD), specifically comparing those with Crohn's disease (CD) to those with ulcerative colitis (UC). Out of nearly 44,620 patients, 174 developed cancer, with a higher rate in CD patients (4.5 per 1,000) compared to UC patients (3.3 per 1,000). Key risk factors included certain disease behaviors and past surgeries; for example, CD patients who had severe disease features or were treated with specific medications were more likely to get cancer. Who this helps: This information helps doctors better assess cancer risks in IBD patients and guide treatment decisions.

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This medical report was about a patient who developed a type of bowel obstruction known as gallstone ileus after having surgery for Crohn's disease. However, the report has been withdrawn because it contained major mistakes, including mixing up this case with a different one. This is important because accurate medical records are crucial for patient care and understanding of diseases. Who this helps: This helps patients and their families.

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This study looked at the structure of the median nerve, which is often affected in carpal tunnel syndrome (CTS), using advanced MRI technology. Researchers found that healthy individuals have between 13 to 23 axonal bundles in their median nerve, while patients with CTS showed higher T2 values (24.27 milliseconds) compared to healthy volunteers (21.01 milliseconds), indicating potential nerve damage. Understanding these differences is important for better diagnosing and managing CTS. Who this helps: This research benefits patients with carpal tunnel syndrome and their doctors by improving diagnostic techniques.

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This study looked at how parent birds, specifically blue tits, decide to protect their young from predators and how their own safety influences these decisions. Researchers found that birds adjusted their defenses based on their own risk, but not as much based on the risk to their chicks; they only considered the risk to their chicks when they were using a safer approach. This difference in how parents manage risk is important because it can affect the survival of their young and has broader implications for understanding decision-making in both animals and humans. Who this helps: This research benefits scientists studying animal behavior and parents in understanding instincts related to child protection.

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This study looked at how the different types of Crohn's disease (CD) affect the time it takes to get diagnosed and how this delay impacts treatment and patients' quality of life. Out of 361 patients, those with the penetrating type of CD had a 59% chance of being diagnosed late, compared to 21% for inflammatory and 27% for stricturing types. Patients who were diagnosed within 18 months reported better quality of life and had fewer surgery needs, highlighting the importance of timely diagnosis based on the type of CD. Who this helps: This helps patients with Crohn's disease and their doctors by emphasizing the need for quicker diagnoses.

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This study looked at the link between rosacea, a skin condition, and infections caused by Helicobacter pylori (H. pylori) and small intestinal bacterial overgrowth (SIBO). Researchers found that 48.9% of rosacea patients had H. pylori compared to 26.7% of those without rosacea. Treating the H. pylori infection significantly improved skin symptoms, with 97.2% of those treated seeing a major decrease in lesions, while SIBO did not show a significant impact. Who this helps: This helps patients with rosacea by identifying a treatable infection that can alleviate their symptoms.

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This study looked at a rare condition called gallstone ileus, which can cause blockages in the bowel, particularly in patients with Crohn's disease. The case involved a patient who had surgery for Crohn's disease 40 years earlier and later developed gallstones that led to a bowel blockage. During surgery, doctors found gallstones causing the problem and had to remove a significant portion of the bowel, but the patient recovered well afterward and needed ongoing nutritional support. Who this helps: This information benefits doctors treating Crohn's disease patients, as it emphasizes the importance of monitoring for gallstones in those with certain types of previous surgeries.

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This study looked at how common coeliac disease is in the Campania region of Italy between 2011 and 2013. Researchers found 2,049 diagnoses, with a rate of 11.8 cases per 100,000 people each year; rates were significantly higher in children (27.4 per 100,000) compared to adults (7.3 per 100,000), and more women (70.4%) were diagnosed than men. These findings highlight a need for greater awareness and education about coeliac disease, especially in areas like Benevento, where diagnosis rates are much lower. Who this helps: This benefits patients and doctors by improving awareness and diagnosis of coeliac disease.

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This study looked at how surgeons in Italy manage patients with ulcerative colitis (UC), a condition that sometimes requires surgery despite successful medical treatment for many patients. The group of colorectal surgeons reviewed existing guidelines and found areas where there is disagreement about surgical practices. They focused on improving how these guidelines are applied in real-life situations to ensure better patient outcomes. Who this helps: This helps patients with ulcerative colitis and their doctors.

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This study focused on how Italian surgeons approach the surgical treatment of Crohn's disease, a type of inflammatory bowel disease. The surgeons discussed their opinions on various treatment practices, revealing that there are significant differences in how guidelines are followed. They highlighted areas of disagreement and suggested ways to make treatment more consistent and effective for patients. Who this helps: This helps patients with Crohn's disease by improving the quality of surgical care they receive.

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This study looked at the risk of breast cancer in female relatives of patients with Crohn's disease compared to those related to people without gastrointestinal diseases. Researchers found that female relatives of Crohn's patients had a significantly higher risk of developing breast cancer—about 3.7 times more likely for mothers of Crohn's patients—and they were often diagnosed at more advanced stages of cancer. This matters because it suggests that these relatives should be screened more actively for breast cancer to catch the disease early. Who this helps: Female relatives of Crohn's disease patients.

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This study looked at fatigue in patients with inflammatory bowel diseases (IBD) compared to other patients, finding that IBD patients experienced more severe fatigue. Specifically, IBD patients had higher fatigue scores, with a significant difference noted regardless of their age or how active their disease was. For those with moderate to severe disease activity, the fatigue was even worse, highlighting that younger IBD patients in remission might still feel fatigued more than their older counterparts. Who this helps: This research helps IBD patients and their doctors understand the severity of fatigue in managing the disease.

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This study looked at a specific genetic variation called Arg72Pro in patients with ulcerative colitis (UC), a condition that affects the large intestine. Researchers analyzed 264 patients—234 were treated with medication and 30 underwent surgery. They found that patients with the Pro/Pro genetic variation were more likely to need surgery (23.3% of surgical patients had this variant compared to just 7.7% of those treated with medication), indicating that this genetic marker could help identify patients who might not respond well to standard treatments and may benefit from surgery instead. Who this helps: This helps patients with ulcerative colitis and their doctors by guiding treatment decisions.