Giovanni Landolfo studies parasitic infections, specifically anisakidosis, which is caused by the Anisakis parasite found in raw or undercooked fish. He investigates cases where this infection leads to severe abdominal issues, such as intestinal blockages. Landolfo's research is significant for individuals who enjoy eating seafood, as it sheds light on the potential health dangers and the importance of proper food preparation. His findings also provide valuable insights for healthcare providers when managing similar infections in patients, especially those with compromised immune systems.
Key findings
A unique case of a 52-year-old woman with anisakidosis who experienced severe abdominal pain and vomiting due to intestinal blockage.
The Anisakis parasite was confirmed in the woman's intestinal wall after surgical intervention, demonstrating the infection's severity.
The study emphasizes that patients with weakened immune systems are at higher risk for severe complications from anisakidosis.
Frequently asked questions
Does Dr. Landolfo study parasitic infections?
Yes, Dr. Landolfo focuses on parasitic infections, particularly anisakidosis from eating raw or undercooked fish.
What treatment options are available for anisakidosis?
Treatment often involves surgery to remove the blockage caused by the parasite, along with supportive care for symptoms.
Who is at risk for diseases caused by eating raw fish?
Individuals who consume raw or undercooked fish, especially those with weakened immune systems, are at a higher risk for parasitic infections like anisakidosis.
Publications in plain English
The HELLP syndrome: clinical issues and surgical management. A Case Experience.
2023
Annali italiani di chirurgia
De Luca GM, Danese V, Franzoso L, De Luca A, De Luca FL +5 more
Plain English This study looked at a serious condition called HELLP syndrome in a pregnant woman who had bleeding in her liver and spleen. The doctors performed an emergency cesarean section and treated her bleeding by packing the areas with gauze, which was successful in keeping her and the baby stable. Fast treatment improved the chances of survival for both the mother and her child, highlighting the importance of quick action in emergency medical situations.
Who this helps: This research helps pregnant women with HELLP syndrome and the doctors treating them.
Surgery for isolated liver metastases from pancreatic cancer.
2015
Updates in surgery
Zanini N, Lombardi R, Masetti M, Giordano M, Landolfo G +1 more
Plain English This study looked at the outcomes of surgery for patients with liver cancer that spread from pancreatic cancer between 2003 and 2014. Out of 15 patients, those with liver metastases that occurred after the initial pancreatic cancer diagnosis lived longer on average—11.4 months—compared to 8.3 months for those with metastases that appeared at the same time as the pancreatic cancer. This finding is important because it suggests that the timing of when liver metastases occur can affect survival, which might help doctors decide who might benefit from surgery.
Who this helps: Patients with pancreatic cancer and liver metastases.
Estimation of the prevalence of asymptomatic pancreatic cysts in the population of San Marino.
2015
Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.]
Zanini N, Giordano M, Smerieri E, Cipolla d'Abruzzo G, Guidi M +9 more
Plain English This study looked at the occurrence of pancreatic cysts in the people of San Marino using CT scans. They found that about 5.4% of patients had at least one cyst, and the likelihood of having a cyst increased significantly with age, reaching 13.4% in those aged 80-89 years. Understanding how common these cysts are, especially in older adults, is important because it can help doctors identify and manage potential health issues more effectively.
Who this helps: Patients, especially older adults, and their doctors.
Chronic anisakidosis presenting with intestinal intussusception.
2014
European review for medical and pharmacological sciences
Piscaglia AC, Ventura MT, Landolfo G, Giordano M, Russo S +4 more
Plain English This study looked at a unique case of a 52-year-old woman who developed a parasitic infection from eating raw or undercooked fish. She experienced severe abdominal pain and vomiting due to a blockage in her intestines, which was caused by the Anisakis parasite. After surgery, doctors confirmed the presence of this parasite in her intestinal wall, highlighting the potential severity of anisakidosis, especially in patients with weakened immune systems.
Who this helps: This helps patients who eat raw fish and may be at risk for parasitic infections, as well as doctors treating similar cases.
Analysis of prognostic factors in metastatic tumors of the pancreas: a single-center experience and review of the literature.
2010
Pancreas
Masetti M, Zanini N, Martuzzi F, Fabbri C, Mastrangelo L +5 more
Plain English This study looked at patients with metastatic tumors in the pancreas, specifically analyzing data from 234 cases, including 9 patients treated at their medical center from 2003 to 2008. It found that most pancreatic metastases came from kidney cancer, and several factors like having symptoms at diagnosis or not undergoing surgery were linked to shorter survival times. Notably, patients with metastases from melanoma and lung cancer had significantly worse survival compared to those with kidney cancer.
Who this helps: This research benefits doctors and patients dealing with pancreatic metastases, as it helps identify who may have better or worse outcomes and the potential role of surgery.
A laparoscopic approach to left diaphragmatic rupture after blunt trauma.
2009
Acta chirurgica Belgica
Ouazzani A, Guerin E, Capelluto E, Landolfo G, Roman A +2 more
Plain English This study examined a 24-year-old man who suffered a ruptured left diaphragm after a serious car accident. The doctors used a laparoscopic (minimally invasive) method to fix his injuries, including repairing the diaphragm and closing a small tear in his intestine. They found that this approach is highly effective for quickly and safely treating such injuries in patients who are stable.
Who this helps: This benefits patients with diaphragm injuries from car accidents or similar trauma.
Major hepatectomy in patients with synchronous colorectal liver metastases: whether or not a contraindication to simultaneous colorectal and liver resection?
2007
Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
Jovine E, Biolchini F, Talarico F, Lerro FM, Mastrangelo L +5 more
Plain English This study looked at patients with colorectal cancer that had spread to the liver and assessed whether it was safe to remove both the colon and liver tumors at the same time. Among the 16 patients who had this combined surgery, 10 underwent a major liver removal, with no deaths and a 25% rate of complications. After one year, about 76.5% of patients were still alive, which shows that doing both surgeries together can be effective and safe.
Who this helps: This benefits patients with colorectal cancer that has spread to the liver.
[Laparoscopic colorectal surgery: is the "learning curve" necessary?].
2005
Annali italiani di chirurgia
Jovine E, Talarico F, Bolchini F, Landolfo G, Mastrangelo L +6 more
Plain English This study looked at the early experiences of a surgical team using laparoscopic techniques for colorectal surgery involving 53 patients with various conditions. They found that the average time for surgery was about 200 minutes, patients stayed in the hospital for about 6 days on average, and there was a low death rate—only one patient died within 30 days after surgery. The results showed that as the surgical team gained more experience, they became faster and had fewer complications, suggesting that this type of surgery can lead to quicker recoveries for patients.
Who this helps: This helps patients needing colorectal surgery by providing them with effective and less invasive options.
[Surgical therapy of Crohn's disease: observations on 63 patients].
2004
Minerva chirurgica
Rossi A, Sforza N, Landolfo G, Malagoli M
Plain English This study looked at 63 patients with Crohn's disease who had surgery between 1973 and 2002 to understand when surgery is necessary. The results showed that out of 56 patients who underwent surgery, most experienced good control of their disease, with only one patient having a high level of disease activity after the operation. Additionally, 17 patients had relapses about five years later, indicating that while surgery can help, most treatment should focus on medication for managing Crohn's disease.
Who this helps: This findings benefit patients with Crohn's disease and their doctors by guiding treatment choices.
Intrahepatic rupture of a caudate lobe adenoma in liver adenomatosis.
2004
Journal of hepato-biliary-pancreatic surgery
Jovine E, Biolchini F, Talarico F, Lazzari A, Lerro FM +3 more
Plain English This study looked at a rare liver condition called hepatic adenomatosis, which mostly affects young to middle-aged women and can lead to problems like bleeding. Researchers reported a case where a benign tumor in the liver ruptured in a young patient, highlighting the challenges in managing this condition because potential complications are hard to predict apart from the size of the tumors. Understanding these cases is important for improving treatment options, as surgery is often necessary but the best approach can vary.
Who this helps: This helps patients with hepatic adenomatosis and their doctors.
Immunocytochemical increased evidence of inducible nitric oxide synthase, tumor necrosis factor-alpha, and adrenocorticotropic hormone in human peritumoral lymph nodes.
Rossi A, Landolfo G, Sassi D, Franchini A, Ottaviani E
Plain English This study looked at lymph nodes from patients with colon and rectal cancer to see how their structure and chemical makeup differed. Researchers found that lymph nodes near the tumors showed higher levels of certain markers related to inflammation and cancer development compared to healthy lymph nodes, indicating significant changes even before any visible signs of disease appeared. This is important because it helps us understand how the body reacts to cancer early on, which could lead to better monitoring and treatment strategies.
Who this helps: This helps patients and doctors by providing insights for earlier cancer detection and management.