Giuseppe Boccia studies multiple aspects of patient care and treatment effectiveness, particularly in the context of chronic diseases and antibiotic resistance. He explores how tools like laminar airflow devices can create safer environments for eye injections, investigates new ways to combat antibiotic resistance, and develops scoring systems to better measure physical health in aging populations. In addition, Boccia examines the impacts of nursing interventions on quality of life for patients post-COVID-19 and analyzes the effects of digital education on chronic disease management. His research is rooted in a practical understanding of how healthcare delivery can be optimized for better patient outcomes.
Key findings
The use of a laminar airflow unit reduced bacterial presence during intravitreal injections from about 90 bacteria per minute to 11, an 88% decrease.
Family and Community Nurse interventions led to a 34% improvement in quality of life and a 26% reduction in hospital readmissions for chronic patients after COVID-19.
In a study of 812 participants, a new Physical Capacity Score revealed that all physical abilities declined with age, particularly in cardiorespiratory fitness.
Infections from harmful bacteria increased from 1,679 to 1,186 over a nine-year period, with more than 90% of bacteria showing resistance to several common antibiotics.
Digital education programs for patients with chronic diseases have the potential to significantly enhance self-care and adherence to treatment over a year.
Frequently asked questions
Does Dr. Boccia study antibiotic resistance?
Yes, he focuses on how to combat antimicrobial resistance using natural substances and new approaches to enhance the effectiveness of existing antibiotics.
What chronic conditions does Dr. Boccia research?
He investigates chronic conditions such as COPD, type 2 diabetes, and the long-term effects of COVID-19 on patients.
How can Dr. Boccia's research help me as a patient?
His findings aim to improve treatment safety and effectiveness, particularly in outpatient procedures and chronic disease management.
What is the Physical Capacity Score created by Dr. Boccia?
It is a tool designed to assess physical abilities in adults, especially as they age, helping to identify declines in health.
Why is Dr. Boccia's work important for healthcare professionals?
His research provides insights and tools that can optimize patient care and improve outcomes in various healthcare settings.
Publications in plain English
The Scaling Factor Between Jump Height and Ground Contact Time in Drop Jumps: A Linear Relationship at the Individual Level.
2026
Journal of strength and conditioning research
Boccia G, Serranò S, Bonelli B, La Torre A, Pavei G
Plain English This study looked at how the height of a jump relates to how long the feet stay on the ground before taking off during drop jumps in young elite track and field athletes. The researchers found that if athletes focused on jumping as high as possible, their jumps were higher by about 4.8 centimeters but took longer to leave the ground by 49 milliseconds. Conversely, trying to leave the ground as quickly as possible decreased jump height by 5.9 centimeters, showing a clear link between jump height and ground contact time.
Who this helps: This helps athletes and coaches understand how to improve jump performance.
EmergInsight: a real-time dashboard for optimizing emergency care through data visualization and analytics.
2026
JAMIA open
Branda F, Andretta V, Ahmed MM, Rizzelli A, Cerrone V +4 more
Plain English This study focused on a new tool called EmergInsight, which is a real-time dashboard designed to improve how emergency departments in Italy operate by using data. The dashboard was tested in a hospital and helped identify important trends, such as that older patients often have a lot of minor emergencies, and it provided accurate forecasts about patient visits. By using EmergInsight, hospitals can better manage their resources and make smarter decisions about patient care.
Who this helps: This benefits emergency department staff and hospital administrators.
Development and validation of the Physical Capacity Score (PiC) to overcome the lack of correlation among traditional physical tests in detecting age-related decline.
2026
PloS one
Boccia G, Brustio PR, Mulasso A, Tufo F, Rainoldi A
Plain English Researchers created a new tool called the Physical Capacity Score (PiC) to test and measure different physical abilities in adults, especially as they age. In a study with 812 participants aged 18 to 68, they found that all physical abilities declined with age, with the strongest effects seen in cardiorespiratory fitness. This study shows that using a variety of physical tests is important to get a complete picture of a person's physical health and to effectively spot declines due to aging.
Who this helps: This helps patients and healthcare providers by offering a more thorough way to assess physical health.
From Polyphenols to β-Lactamases: Multitarget Strategies to Defeat Severe Resistance.
2026
International journal of molecular sciences
Nappa M, Santoro E, Manente R, Cianciulli A, Moccia G +3 more
Plain English This research looks at how to tackle the growing problem of antimicrobial resistance (AMR), which makes standard antibiotics less effective and leads to increased illness and medical costs. It finds that natural substances, like polyphenols, and specially designed small molecules can disrupt bacteria's protective mechanisms, allowing existing antibiotics to work better. These combined approaches could help reduce resistance in bacteria without creating new problems, making them valuable in fighting infections.
Who this helps: This benefits patients and healthcare providers by improving the effectiveness of existing antibiotics.
Mobile Laminar Airflow for Intravitreal Injections: Reducing Microbial Load at the Instrument Field.
2026
Journal of clinical medicine
Satriani V, Boccia G, Santella B, Cione F, Donato A +4 more
Plain English This study looked at how well a mobile air cleaning device, called a laminar airflow (LAF) unit, helps keep the area clean during intravitreal injections (IVIs) in an outpatient setting. Researchers found that while the room air had an average of about 90 bacteria per minute, the LAF unit reduced this to about 11 bacteria per minute, which is nearly an 88% decrease. This is important because it shows that using the LAF unit can help create a much cleaner environment for these procedures, potentially reducing the risk of infections.
Who this helps: This benefits patients receiving eye injections by making the procedure safer.
Strength, Rate of Force Development, and Force Control Evaluations to Quantify Upper-Limbs Asymmetries Agreement in Professional Male Volleyball Players.
2025
Journal of strength and conditioning research
D'Emanuele S, Boccia G, Zardo V, Durigon V, Schena F +1 more
Plain English This study looked at how muscle strength and performance differ between arms in 13 male professional volleyball players. Researchers found that the arms showed a 12% difference in strength for one type of muscle contraction, specifically the biceps, but overall, the players did not show consistent advantages in performance between their hands. Understanding these differences is important for designing effective and personalized training programs for athletes.
Who this helps: This helps coaches and trainers improve training programs for volleyball players.
The Rate of Torque Development as a Determinant of the Torque-Velocity Relationship.
2025
Scandinavian journal of medicine & science in sports
Boccia G, Brustio PR, Salvaggio F, Grossio L, Calcagno E +3 more
Plain English This study looked at how quickly the muscles in the knee can generate force and how this affects their ability to move quickly and powerfully. Researchers tested 64 young adults and found that the speed at which muscles develop force is important for how fast and strong they can work together. Specifically, they discovered that the rate at which torque was built up early in muscle contractions was a key factor for speed, explaining a part of the relationship between strength and speed in leg movements.
Who this helps: This research benefits athletes and individuals undergoing rehabilitation for knee injuries.
Normative cardiorespiratory values in Italian first-division male soccer players: effects of age, playing position and season phase.
2025
Biology of sport
Paco AD, Laveneziana P, Onorati P, Trotta L, Boccia G
Plain English This study looked at the heart and lung performance of top male soccer players in Italy, analyzing data from 741 players over ten years. It found that the average oxygen use reached 4.78 liters per minute, with higher values for midfielders compared to other positions, while overall performance decreases with age. This information is important for training and performance evaluation in professional soccer, ensuring players meet the physical demands of their roles.
Who this helps: This helps coaches, fitness trainers, and players in professional soccer.
Impact of COVID-19 Pandemic on Consumption of Anxiolytics, Antipsychotics, and Antidepressants in South Italian Region.
2025
Life (Basel, Switzerland)
Satriani V, Santoro E, Capunzo M, Ferrara RF, Manente R +4 more
Plain English This study examined how the COVID-19 pandemic affected the use of anxiety, antipsychotic, and antidepressant medications in the Basilicata region of South Italy. Researchers found that from 2019 to 2021, over 85,000 boxes of these medications were dispensed, with a sharp increase of 88.5% in benzodiazepines and 81.9% in antidepressants by 2021, particularly among women under 30. This is important because it highlights the serious impact of the pandemic on mental health and the growing need for mental health support.
Who this helps: This benefits patients, especially young women struggling with mental health issues during the pandemic.
Sex differences in the rate of torque development and torque-velocity relationship are due to maximal strength only.
2025
European journal of applied physiology
Salvaggio F, Brustio PR, Samozino P, Grossio L, Rainoldi A +1 more
Plain English This study looked at how men and women differ in their ability to generate force quickly and their relationship between strength and speed during knee extension exercises. Researchers tested 64 healthy individuals and found that men could produce force faster than women at specific time points (50 ms, 100 ms, and 150 ms) and had greater overall strength. However, when taking into account their maximum strength, these differences disappeared, meaning the explosiveness advantage men have is primarily linked to their overall strength levels.
Who this helps: This research benefits fitness trainers and physical therapists working with both male and female athletes.
Adaptations of Bacterial Extracellular Vesicles in Response to Antibiotic Pressure.
2025
International journal of molecular sciences
Federica D, Cosimato I, Salzano F, Mensitieri F, Andretta V +4 more
Plain English This study looked at how bacteria produce tiny structures called extracellular vesicles (EVs) when they are exposed to antibiotics. Researchers found that these vesicles help bacteria survive by carrying important molecules that aid in antibiotic resistance and help them thrive in tough conditions. Understanding how these vesicles work is crucial because it could lead to new ways to develop treatments, including vaccines and better drug delivery methods.
Who this helps: This helps patients by potentially leading to more effective treatments against antibiotic-resistant infections.
Validation of a Questionnaire on the Post-COVID-19 Condition (Long COVID): A Cross-Sectional Study in Italy.
2025
Infectious disease reports
Cianciulli A, Santoro E, Manente R, Pacifico A, Comunale G +6 more
Plain English This study looked at a questionnaire designed to help understand long COVID, a condition that affects people recovering from COVID-19 with symptoms like fatigue, shortness of breath, and cognitive issues. Researchers tested this questionnaire on 250 people in Italy and found it to be highly reliable, with a score indicating strong consistency (0.97). This matters because it helps doctors and researchers track long COVID symptoms over time, aiding in better care and understanding of how the condition affects daily life.
Who this helps: This helps patients recovering from COVID-19 and their healthcare providers.
Both Isometric and Dynamic Testing Are Essential for a Comprehensive Assessment of the Knee Extensors.
2025
Journal of strength and conditioning research
Grossio L, Salvaggio F, Brustio PR, Rainoldi A, Samozino P +1 more
Plain English This study looked at how to best measure the strength of knee muscles in young adults by using both isometric (muscle contractions without movement) and dynamic (muscle contractions with movement) testing. Researchers found that combining these testing methods leads to a better understanding of muscle performance, especially for explosive strength and how quickly muscles can develop force. Specifically, testing for explosiveness is crucial, as it gives valuable insights into muscle function that may help in sports and rehabilitation settings.
Who this helps: This benefits athletes, physical therapists, and anyone involved in strength training or rehabilitation.
Muscle synergies and metabolic adaptations during perturbed walking in older adults.
2025
Scientific reports
D'Emanuele S, Ghislieri M, Ghiotto L, Morra F, Budel L +5 more
Plain English This study looked at how older adults walk under normal conditions compared to conditions that make walking more challenging, like on a treadmill with interruptions. The researchers found that when walking at a slower speed of 3 km/h, the older adults used more oxygen and energy, and felt it was more difficult, compared to higher speeds—specifically, oxygen use increased by around 52% and energetic cost went up by 112%. This matters because it shows that while older adults can adapt to challenging walking conditions, it requires more effort and energy from them, which is important for understanding their mobility and health.
Who this helps: Older adults and their caregivers.
Comparative Efficiency of Whole-Body Electromyostimulation and Resistance Training in Enhancing 1-Repetition Maximum.
2025
Journal of functional morphology and kinesiology
Grgic V, Grossio L, Mulasso A, Boccia G, Rainoldi A
Plain English This study looked at two types of exercise training: whole-body electromyostimulation (WB-EMS), which uses electrical impulses to stimulate muscles, and traditional resistance training, which involves lifting weights. Over 10 weeks, 20 sedentary women participated, showing that both groups improved their strength similarly: WB-EMS increased squat performance by 36% and curl performance by 42%, while resistance training saw increases of 34% and 33%, respectively. This matters because WB-EMS achieves these results in just 20 minutes a week compared to 120 minutes for traditional training, making it a time-saving option for strength training.
Who this helps: This helps people who have busy schedules and want to improve their strength without committing a lot of time to workouts.
Non-Interventional Monitoring on Antibiotic Consumption in a Critical Care Setting: A Three-Year Comparative Analysis.
2025
Healthcare (Basel, Switzerland)
Santoro E, Russo M, Manente R, Schettino V, Moccia G +4 more
Plain English This study looked at how antibiotics were used in the intensive care unit (ICU) of a university hospital in Italy over three years. They found that the amount of antibiotics prescribed matched national averages, which suggests that regular monitoring can improve how antibiotics are used and encourage better hygiene practices. This is important because inappropriate antibiotic use can lead to drug-resistant infections, which are a major health concern.
Who this helps: This helps patients by promoting safer and more effective antibiotic use in hospitals.
A Comparative Study of Paralympic Veterans with Either a Spinal Cord Injury or an Amputation: Implications for Personalized Nutritional Advice.
2025
Journal of functional morphology and kinesiology
Peluso I, Raguzzini A, Toti E, Boccia G, Ferrara R +7 more
Plain English This study compared the nutritional needs of Paralympic athletes with spinal cord injuries to those with amputations. Researchers found that both groups had similar lifestyles and metabolic responses but noted that athletes with spinal cord injuries experienced more issues with bowel function and had lower exercise capacity. This is important because it shows that athletes with amputations also need tailored dietary guidance despite their differences from those with spinal cord injuries.
Who this helps: This helps athletes with amputations and their coaches.
Efficacy and Safety of Anti-Respiratory Syncytial Virus Monoclonal Antibody Nirsevimab in Neonates: A Real-World Monocentric Study.
2025
Vaccines
Costantino M, Marongiu MB, Corbo MG, Della Corte AM, Frascogna AR +9 more
Plain English This study looked at the effectiveness and safety of a new antibody treatment called nirsevimab for preventing severe respiratory syncytial virus (RSV) infections in newborns. Researchers analyzed data from 2,035 infants and found that after starting nirsevimab, there was a noticeable drop in RSV infections compared to the previous two years, with only one infant needing serious medical intervention and no side effects reported. This is important because it shows that nirsevimab could significantly reduce the risk of severe RSV infections in newborns, which is a major cause of hospitalization.
Who this helps: This helps newborns and their families by reducing the risk of hospitalizations due to RSV.
Sustainable Dental and Periodontal Practice: A Narrative Review on the 4R-Framework-Reduce, Reuse, Rethink, Recycle-And Waste Management Rationalization.
2025
Dentistry journal
Di Spirito F, Giordano F, Di Palo MP, De Benedetto G, Aulisio L +1 more
Plain English This study looked at how dental and gum treatments can be made more environmentally friendly by using a set of strategies known as the 4R-Framework: Reduce, Reuse, Rethink, and Recycle. Researchers found that adopting practices like using energy-saving technologies, minimizing waste, and choosing sustainable materials could greatly decrease the negative impact of dental care on the environment. For example, better waste management and digital tools can lower the energy and water used during treatment.
Who this helps: This benefits patients and dental professionals looking for eco-friendly solutions in oral healthcare.
Assessing health and social care needs of chronic patients in rural areas: Protocol for the CAMP mixed-methods observational study.
2025
PloS one
Cianciulli A, Santoro E, Manente R, Pacifico A, Finizio M +4 more
Plain English This study looked at the health and social care needs of adults with chronic diseases living in rural areas of Southern Italy. Researchers aimed to understand the challenges these patients face, including access to healthcare and social support, by using surveys and interviews. They plan to identify gaps in care and resource distribution, ultimately to help create better healthcare services for these communities.
Who this helps: This helps patients with chronic conditions living in rural areas, as well as their healthcare providers.
Clean to Prevent, Monitor to Protect: A Scoping Review on Strategies for Monitoring Cleaning in Hospitals to Prevent HAIs.
2025
Infectious disease reports
Santella B, Donato A, Fortino L, Satriani V, Ferrara RF +5 more
Plain English This research reviewed how hospitals monitor their cleaning practices to prevent infections that can occur in healthcare settings. The review found that various methods are used: 44% of studies employed microbiological testing, 33% used ATP bioluminescence (a light-based cleanliness test), and 22% used fluorescent markers. However, there is a lack of uniformity in the benchmarks used to gauge cleanliness, which varies widely among studies, and a growing need for better monitoring tools and standards.
Who this helps: This benefits patients by improving hygiene practices in hospitals, leading to a lower risk of infections.
Artificial Intelligence and Digital Technologies Against Health Misinformation: A Scoping Review of Public Health Responses.
2025
Healthcare (Basel, Switzerland)
Cianciulli A, Santoro E, Manente R, Pacifico A, Quagliarella S +3 more
Plain English This study reviewed how artificial intelligence (AI) and digital tools are being used to fight health misinformation, especially during the COVID-19 pandemic. Out of 63 studies examined, most focused on monitoring misinformation and improving health communication, finding that these technologies can effectively identify false information and support health literacy. However, the findings are uneven across different regions, and many vulnerable groups are not adequately covered, indicating a need for better governance and access to these tools.
Who this helps: This helps public health officials and communities working to improve health information access and combat misinformation.
Optimizing Textile Disinfection in Hospital-Associated Infections Using Gaseous Ozone.
2025
Pathogens (Basel, Switzerland)
De Caro F, Dell'Annunziata F, Motta O, Capuano N, Faggiano A +8 more
Plain English This study looked at how effective gaseous ozone is at disinfecting fabrics in hospitals, which are often contaminated with germs that cause infections. Researchers found that treating fabrics with ozone for 45 minutes nearly eliminated these germs, while 25 minutes of treatment significantly reduced the amount of bacteria. This is important because it shows that ozone can clean not only the surface of fabrics but also the hidden areas, making it a better option for preventing hospital-associated infections.
Who this helps: This benefits healthcare workers and patients by reducing the risk of infections in hospitals.
The Impact of the Oral and Esophageal Microbiota in EoE and Achalasia.
2025
Journal of clinical medicine
Manente R, De Caro G, Paris D, Tramice A, Boccia G +3 more
Plain English This research paper looks at how the bacteria in the mouth and esophagus affect two chronic conditions: eosinophilic esophagitis (EoE) and achalasia. It found that in EoE, there’s more bacterial variety, which relates to more inflammation (with specific changes in bacteria), while achalasia has less bacterial variety and different types of bacteria that can worsen symptoms. Understanding these differences could lead to new ways to diagnose and treat these conditions more effectively.
Who this helps: This helps patients with EoE and achalasia, as well as their doctors looking for better treatment options.
Clinical and Symptom Profiles of Long-COVID Patients in Italy: A Cross-Sectional Analysis.
2025
Healthcare (Basel, Switzerland)
Cianciulli A, Santoro E, Manente R, Pacifico A, Barberio I +2 more
Plain English This study looked at the experiences of 250 young adults in Italy who have Long COVID, a condition that continues to cause symptoms after the initial COVID-19 infection. Researchers found that most participants reported persistent issues like extreme tiredness and muscle pain, with women experiencing more fatigue than men. These results underscore the importance of developing comprehensive care strategies and education programs to support patients dealing with the ongoing effects of COVID-19.
Who this helps: This helps patients suffering from Long COVID and their healthcare providers.
Asymmetry Should Be Considered the Norm, Not the Exception: Neuromuscular Asymmetries in Knee Flexors and Extensor Assessed Through a Multimetric Approach.
2025
Sports health
D'Emanuele S, Boccia G, Marcantonio A, Massagrande C, Ghiotto L +2 more
Plain English This study looked at the differences in strength and performance between the dominant and nondominant legs of 71 people, focusing on their knee muscles. Researchers found that while some measurements showed slight differences, like how quickly force was developed in the muscles, overall, three-quarters (75%) of the participants exhibited some form of muscle imbalance. This matters because it emphasizes the need for thorough evaluations of muscle performance to create personalized training programs that can address these imbalances.
Who this helps: Patients, especially athletes and individuals in rehabilitation, can benefit from tailored workout plans.
Knowledge, Perceptions, and Behaviors Regarding Antibiotic Use in a Community-Based Adult Sample in Salerno: An Observational Survey in a Province in Southern Italy.
2025
Antibiotics (Basel, Switzerland)
Santoro E, Amelio R, Manente R, Speziga G, Donato A +2 more
Plain English This study looked at how well adults in Salerno, Italy, understand and use antibiotics. Out of 325 participants, 90.2% said they only take antibiotics when a doctor prescribes them, but 10% reported self-medicating and 16% stopped taking their antibiotics early. Additionally, many still hold misconceptions, such as 86% thinking that antibiotic resistance affects only them rather than the wider community. This is important because it highlights the need for better education about antibiotic use, especially for older adults, to help combat the rise of antibiotic resistance.
Who this helps: This helps patients and healthcare providers by promoting safer antibiotic practices.
Digital Educational Intervention to Improve Adherence and Self-Care in Chronic Patients: A Prospective Study Protocol (PROSELF).
2025
Healthcare (Basel, Switzerland)
Cianciulli A, Boccia G, Manente R, Pacifico A, Speziga G +1 more
Plain English This study looked at how a year-long digital education program led by nurses can help patients with chronic diseases like COPD, type 2 diabetes, and heart issues better manage their health. Researchers plan to measure improvements in self-care and adherence to treatment over 12 months, using tools that assess patients' quality of life and support systems. The findings will help create effective digital care strategies for chronic illness management.
Who this helps: This helps patients dealing with chronic conditions and the healthcare providers caring for them.
A Nine-Year Review ofInfections Frequency and Antimicrobial Resistance in a Single-Center Study in Salerno, Italy.
2025
Pathogens (Basel, Switzerland)
Serretiello E, De Prisco M, Di Siervi G, Cosimato I, Dell'Annunziata F +5 more
Plain English Researchers studied infections linked to a harmful bacteria in Salerno, Italy, over a nine-year period. They found that from 2015 to 2019, there were 1,679 infections, and from 2020 to 2023, there were 1,186 infections, with more cases in older men and women. The study revealed that this bacteria had high resistance to several antibiotics, with more than 90% resistance to drugs like gentamicin and ciprofloxacin, while resistance to colistin rose from less than 1% pre-pandemic to 6.1% during and after the pandemic. This is important because it shows a rising threat of antibiotic resistance, stressing the need for ongoing monitoring and new treatment options.
Who this helps: This helps patients, doctors, and public health officials.
Reduced knee extensor torque steadiness and increased motor unit discharge rate variability in young people with patellofemoral pain: a pilot study.
2025
European journal of applied physiology
Arvanitidis M, Falla D, Negro F, Boccia G, Rainoldi A +1 more
Plain English This study looked at how the muscles in the thighs of young people with patellofemoral pain (PFP) behave when performing exercises. Researchers found that those with PFP had less steady muscle contractions and more inconsistent muscle firing compared to healthy individuals, particularly during exercises focused on the knee extension. Specifically, during intense contractions (up to 70% of their max effort), the muscle firing was more variable, which suggests that pain may be affecting their muscle control.
Who this helps: This helps patients with patellofemoral pain by providing insights into their muscle control issues during exercise.
The Role of the Family and Community Nurse in Improving Quality of Life and Optimizing Home Care Post-COVID: A Systematic Review with Meta-Analysis.
2025
Nursing reports (Pavia, Italy)
Cianciulli A, Santoro E, Bruno N, Quagliarella S, Esposito S +6 more
Plain English This research looked at how Family and Community Nurses (FCNs) can improve the quality of life for patients, particularly those living with chronic conditions after COVID-19. The study found that FCN-led interventions, like home visits and telehealth, led to a 34% improvement in quality of life and a 0.47% drop in blood sugar levels. Additionally, these interventions reduced hospital readmissions by 26%, showing that having FCNs involved in care can greatly benefit patients' health and well-being.
Who this helps: This helps patients living with chronic conditions and their families.
Decreased neural drive affects the early rate of force development after repeated burst-like isometric contractions.
2024
Scandinavian journal of medicine & science in sports
Boccia G, D'Emanuele S, Brustio PR, Rainoldi A, Schena F +1 more
Plain English This study examined how quick, repeated muscle contractions affect the ability of the nervous system to trigger muscle force. Researchers found that after 100 short bursts of muscle activity, the speed at which the muscle generated force decreased significantly in the first 50 milliseconds, showing a 56% reduction. This is important because it indicates that intense, rapid movements can deteriorate muscle response, potentially impacting athletic performance and rehabilitation.
Who this helps: This helps athletes and rehabilitation patients looking to optimize their muscle performance.
A Novel DNA Variant inGene Found in a Patient Affected by Early Onset Colon Cancer.
2024
International journal of molecular sciences
Di Maggio F, Boccia G, Nunziato M, Filotico M, Montesarchio V +3 more
Plain English This study focused on a woman with early onset colon cancer, meaning she was diagnosed before the age of 50. Researchers found a new DNA change in a gene that helps with damage repair, which may be linked to her cancer. They emphasized that genetic testing for such changes is important for younger patients, as it can help identify risks for early onset cancers.
Who this helps: This helps patients under 50 and their doctors find potential genetic risks more effectively.
Current Epidemiological Status and Antibiotic Resistance Profile of.
2024
Antibiotics (Basel, Switzerland)
Cosimato I, Santella B, Rufolo S, Sabatini P, Galdiero M +4 more
Plain English This study looked at the patterns of antibiotic resistance in bacteria collected from patients over seven years at a hospital in Salerno, Italy. Researchers found that 396 samples of a specific bacterium were tested, with troubling signs of increasing resistance to important antibiotics, especially carbapenems. This is concerning because it could lead to more severe infections and higher death rates, especially among vulnerable patients like those with weakened immune systems or newborns.
Who this helps: This research benefits patients, particularly those in hospitals who are at risk for serious infections.
Antimicrobial Susceptibility Profiles ofStrains Collected from Clinical Samples in a Hospital in Southern Italy.
2024
The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale
Santella B, Boccella M, Folliero V, Iervolino D, Pagliano P +8 more
Plain English Researchers studied antibiotic-resistant bacteria collected from clinical samples at a hospital in Southern Italy between 2015 and 2020. They found that over 3,800 bacterial strains showed high resistance to common antibiotics like penicillin and cephalosporins, with 40% resistant to meropenem and 44% resistant to ertapenem. This matters because these resistant strains are significant contributors to serious infections like septicemia and pneumonia, highlighting the urgent need for monitoring and effective treatment strategies.
Who this helps: This information benefits doctors and healthcare providers in treating patients with infections.
Performance pathways in elite middle- and long-distance track and field athletes: The influence of a successful youth.
2024
Journal of science and medicine in sport
Brustio PR, Stival M, Cardinale M, Mulasso A, Rainoldi A +1 more
Plain English This study looked at how young athletes in middle- and long-distance running transition to elite adult competitors. It found that only about 19% of male and 21% of female top youth athletes make it to the senior elite level, but top youth athletes are about seven times more likely to succeed than those who weren't top performers. Although being a successful youth athlete can help, it doesn't guarantee that they will be successful as adults.
Who this helps: This information is useful for coaches and sports organizations to better support young athletes in their development.
Mitigating against relative age effects in youth Track & Field: Validating corrective adjustment procedures across multiple events.
2024
Journal of science and medicine in sport
Brustio PR, Boccia G, Abbott S, La Torre A, Rainoldi A +1 more
Plain English This study looked at how a child's age affects their performance in Track & Field events like sprints and jumps. By analyzing data from over 5,300 young athletes in Italy, researchers found that younger athletes in a group often perform better just because they're older than their peers, which is known as the Relative Age Effect (RAE). The study showed that applying corrective adjustments significantly minimized these age-related performance disparities, leading to fairer evaluations and potentially better training programs.
Who this helps: This benefits young athletes, coaches, and sports organizations.
Upper-Limb Muscle Fatigability in Para-Athletes Quantified as the Rate of Force Development in Rapid Contractions of Submaximal Amplitude.
2024
Journal of functional morphology and kinesiology
Boccia G, Brustio PR, Beratto L, Peluso I, Ferrara R +5 more
Plain English This study looked at how quickly and powerfully the arm muscles tire out in two groups of para-athletes: those with spinal cord injuries and those with amputations. The researchers found that athletes with spinal cord injuries produced less force and were slower to recover from fatigue compared to those with amputations. Specifically, athletes with spinal cord injuries showed a significant drop in their muscle strength after intense exercise, which could impact their performance in sports and daily activities.
Who this helps: This benefits athletes with spinal cord injuries and their coaches.
Reduced rate of force development under fatigued conditions is associated to the decline in force complexity in adult males.
2024
European journal of applied physiology
D'Emanuele S, Boccia G, Angius L, Hayman O, Goodall S +2 more
Plain English This study looked at how fatigue affects muscle control in adult men during exercise. The researchers found that as muscles became fatigued, the speed at which they could generate force dropped significantly, with reductions of around 39% to 46%. This decrease in force generation also made it harder to control muscle movements, as indicated by increased fluctuations and reduced complexity of muscle contractions.
Who this helps: This benefits patients undergoing rehabilitation or athletes looking to improve their performance and recovery strategies.
Influence of Mycobiota in the Nasopharyngeal Tract of COVID-19 Patients.
2024
Microorganisms
Folliero V, Ferravante C, Dell'Annunziata F, Brancaccio RN, D'Agostino Y +9 more
Plain English This study examined the fungal community in the noses and throats of 55 COVID-19 patients in Italy to see how the virus affects it. The researchers found that patients with severe COVID-19 symptoms had more of certain types of fungi and that the diversity of fungi was higher during the second wave of infections. Understanding these changes is important because it might help develop better treatments for COVID-19.
Who this helps: This helps patients and doctors by providing insights that could lead to improved care and treatment strategies.
Impact of ESKAPE Pathogens on Bacteremia: A Three-Year Surveillance Study at a Major Hospital in Southern Italy.
2024
Antibiotics (Basel, Switzerland)
De Prisco M, Manente R, Santella B, Serretiello E, Dell'Annunziata F +8 more
Plain English This study looked at how often dangerous bacteria, known as ESKAPE pathogens, cause bloodstream infections (BSIs) in patients at a hospital in Southern Italy over three years. They found that out of nearly 3200 bacteria samples tested, about 39% were ESKAPE pathogens, with a higher occurrence in men and people over 60 years old. Alarmingly, significant antibiotic resistance was observed, with 35% being resistant to oxacillin and over 90% resistant to carbapenems, indicating a critical need to improve how we use antibiotics to avoid severe infections.
Who this helps: This helps patients at risk of serious infections and doctors treating them.
Unveiling the Burden of Hepatitis A in Salerno, Italy: A Comprehensive 9-Year Retrospective Study (2015-2023) on the Seroprevalence of HAV Antibodies and Age/Sex Distribution.
2024
Journal of clinical medicine
Serretiello E, Iervolino D, Di Siervi G, Gallo L, Bernardi FF +5 more
Plain English This study looked at how many people in Salerno, Italy, are protected against Hepatitis A (HAV) by testing samples over nine years from 2015 to 2023. They found that out of 28,104 samples, 20,613 were positive for HAV antibodies, indicating that many people had immunity, but this number dropped during the COVID-19 pandemic. More men had immunity than women, especially in the 61-70 age group, which suggests that some age and gender groups are more vulnerable.
Who this helps: This information benefits public health officials and patients by highlighting the need for better vaccination strategies.
Age Differences and Prevalence of Comorbidities for Death and Survival in Patients with COVID-19: A Single-Center Observational Study in a Region of Southern Italy.
2024
Life (Basel, Switzerland)
Santella B, Aliberti SM, Fortino L, Donato A, Andretta V +4 more
Plain English This study looked at 1,985 COVID-19 patients in southern Italy to understand how age and pre-existing health conditions affected their chances of surviving the virus. They found that 32% of patients died, most of whom were aged 60-79, with heart and lung diseases being the most common issues among those who died. This research stresses the importance of addressing health problems in older patients to improve their chances during COVID-19 infections.
Who this helps: This helps patients with pre-existing health conditions, especially older adults.
Pre- and Post-COVID-19 Antibiotic Consumption and Stewardship Program in a Southern Italian Hospital.
2024
Antibiotics (Basel, Switzerland)
Costantino M, Giudice V, Campana F, Iannelli AA, Scala P +9 more
Plain English This study looked at how well a program aimed at improving antibiotic use in a hospital in southern Italy worked before and after the COVID-19 pandemic. After implementing the program, the use of appropriate antibiotics improved significantly, with better choices made about common and targeted treatments, although prescriptions for strong antibiotics increased to about 10% in 2023. This is important because it helps fight antibiotic resistance, which can lead to serious health issues and increased costs for healthcare.
Who this helps: Patients and healthcare providers.
Assessment of Ultrasound Utilization for Peripheral Venous Access in Nursing Practices. An Observational Study From an Italian University Hospital.
2024
Translational medicine @ UniSa
Cerrone V, Andretta V, Prendin A, Romano N, Strini V +3 more
Plain English The study examined how often nurses at an Italian university hospital use ultrasound to help insert IVs in patients, especially when it’s difficult. Out of 64 nurses, 60.9% had some training in ultrasound, but only half used it regularly for IVs, and only 26.6% used it to help position the catheter correctly. Improving training could lead to better outcomes for patients by reducing complications and speeding up care.
Who this helps: This helps patients who need IV access and may face difficulties during the process.
Effective Neutralizing Antibody Response Against SARS-CoV-2 Virus and Its Omicron BA.1 Variant in Fully Vaccinated Hematological Patients.
2023
Clinical and experimental medicine
De Novellis D, Folliero V, Giudice V, Pezzullo L, Sanna G +19 more
Plain English This study looked at how well fully vaccinated patients with blood cancers respond to the antibodies that fight COVID-19, specifically the original virus and the Omicron BA.1 variant. Out of 106 patients, 71% showed a strong antibody response to the original virus, while 82% did for the Omicron variant. However, patients with certain blood cancers, especially those treated with a specific antibody therapy, had lower response rates (73% for Omicron and 64% for the original virus) compared to others.
Who this helps: This research benefits patients with blood cancers and their doctors by highlighting the importance of continued protective measures for those with a weaker immune response.
Celiac Disease on the Bed-Side: Embedding Case Finding and Screening in Hospitalized Children.
2023
Nutrients
Pepe A, Mandato C, Di Leo T, Boccia G, Lucaroni G +4 more
Plain English This study looked at how often celiac disease (CD) occurs in hospitalized children in a Southern Italy hospital from 2018 to 2021. Out of 1320 children screened, 1.59% were newly diagnosed with CD, and 3.86% had CD autoimmunity, which means they had signs of the disease without a formal diagnosis. This is important because it shows that testing for celiac disease during hospital stays can help identify more cases, especially in kids who might be struggling with issues like malnutrition.
Who this helps: This benefits patients, especially children with celiac disease or related health issues.
Scale of Assessment of Caregiver Care Burden of People With Dementia: A Systematic Review of Literature.
2023
Translational medicine @ UniSa
Strini V, Prendin A, Cerrone V, Schiavolin R, de Barbieri I +6 more
Plain English This study looked at how to measure the stress and challenges that family caregivers face when taking care of loved ones with dementia. After examining 116 published articles, the researchers identified 18 effective tools to assess caregiver burden, which can be categorized into different types based on what they measure. Understanding and using these tools can help improve the well-being of caregivers, both at home and in medical settings, where caregiver stress is often higher.
Who this helps: This benefits caregivers of people with dementia and healthcare providers who support them.