Department of Health Surveillance and Bioethics, Section of Legal Medicine, Università Cattolica del Sacro Cuore, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Giuseppe Vetrugno studies several key areas in healthcare, particularly focusing on how different factors affect patient outcomes. He investigates the effects of waiting times in emergency departments on patient survival, examines complications arising from cancer treatments like CAR-T therapy and stem cell transplants, and analyzes vaccination effectiveness among healthcare workers. His research also delves into the role of new technologies in medicine, particularly how they reshape ethical practices in patient care. By examining these topics, he aims to enhance both patient safety and the overall efficacy of medical treatments.
Key findings
In a study of over 56,000 emergency room patients, triage color codes were found to be important factors in predicting one-year mortality, especially among elderly patients with yellow codes, while waiting times did not significantly affect long-term survival outcomes.
Among 498 patients receiving CAR-T therapy, higher instances of falls and clinical complications were reported, emphasizing the need for careful patient support during these treatments.
Vaccination rates for influenza among healthcare workers peaked at 46% during the COVID-19 pandemic but returned to pre-pandemic levels thereafter; special vaccination events significantly boosted acceptance rates.
In robotic surgeries, claims of malpractice increased by 27% from 2015 to 2024, highlighting growing legal scrutiny, although these surgeries also showed a lower complication rate than traditional methods.
Patients with severe obstructive sleep apnea exhibited average interleukin-6 levels of 7.38, significantly higher than the 2.20 in healthy individuals, indicating a potential link between inflammation and cognitive decline.
Frequently asked questions
Does Dr. Vetrugno study cancer treatments?
Yes, he researches cancer therapies, particularly hematopoietic stem cell transplants and CAR-T therapy, focusing on their complications and outcomes.
What are the main findings from Dr. Vetrugno's research on emergency departments?
His research indicates that while triage color codes are crucial for predicting one-year mortality, waiting times in emergency departments do not significantly affect long-term survival for patients with less urgent conditions.
How does Dr. Vetrugno's work impact vaccination strategies?
His studies show that special vaccination events can significantly increase vaccination rates among healthcare workers, which is vital for public health.
Is Dr. Vetrugno's work relevant to patient safety in surgeries?
Yes, he examines the safety of robotic surgeries and has highlighted a rise in malpractice claims despite lower complication rates, underlining the importance of patient safety in surgical practices.
What specific healthcare practices does Dr. Vetrugno evaluate?
He evaluates practices in emergency medicine, cancer treatment, patient safety culture, vaccination strategies, and the integration of technology in healthcare.
Publications in plain English
Differences between Physicians' and Nurses' Perspectives in Defining Core Nursing-Sensitive Outcomes in Adult HSCT and CAR-T Therapy: An Interdisciplinary Italian Delphi Consensus.
2026
Bone marrow transplantation
Cioce M, Sica S, Liptrott SJ, Lamberti F, Calza S +9 more
Mercuri G, Mustè E, Galluccio E, Nicolotti N, Refolo P +2 more
Plain English This study looked at the effects of robotic surgery on patient safety and legal claims at a hospital in Rome from 2015 to 2024. It found that claims related to robotic surgeries increased by 27%, particularly in fields like Gynecology and Urology, where most disputes stemmed from surgical errors. Interestingly, robotic surgeries had a lower complication rate compared to traditional laparoscopic surgery, suggesting that while claims are rising, robotic methods might actually be safer.
Who this helps: This helps patients and healthcare providers by improving surgical safety and communication.
Assessing vaccine coverage and delivery strategies for influenza and COVID-19 among Italian healthcare workers: A 2015-2023 case study.
2025
Human vaccines & immunotherapeutics
Pascucci D, Lontano A, Marziali E, Vetrugno G, Moscato U +3 more
Plain English This study looked at how well healthcare workers in Italy have been getting vaccinated against influenza and COVID-19 from 2015 to 2023. It found that vaccination rates for the flu peaked at 46% during the first year of the COVID-19 pandemic but then dropped back to pre-pandemic levels. The study also revealed that special events, like “open-day” vaccination days, greatly increased flu vaccine acceptance, while hospital outpatient services were the best for combining flu and COVID-19 vaccines.
Who this helps: This benefits healthcare workers and ultimately their patients by improving vaccination rates and safety.
Perception of 'patient safety culture' among healthcare professionals in the field of haematopoietic stem cell transplantation and CAR-T therapy: a multicentre cross-sectional observational study by Italian Transplant Group for Bone Marrow Transplantation, Haematopoietic Stem Cells and Cell Therapy (GITMO).
2025
BMJ open quality
Cioce M, Vetrugno G, Iula A, Cornacchione P, Botti S +30 more
Plain English This study examined how healthcare professionals feel about patient safety in the areas of stem cell transplantation and CAR-T therapy. Out of 166 surveyed professionals, hematologists rated their perception of safety culture more positively compared to nurses, with over 75% of hematologists responding favorably on key topics like teamwork and error communication. Improving safety culture is important because it can lead to fewer mistakes in these high-risk medical fields, benefiting patient care and outcomes.
Who this helps: Patients undergoing stem cell transplants or CAR-T therapy.
Technological Advances in Healthcare and Medical Deontology: Towards a Hybrid Clinical Methodology.
2025
Healthcare (Basel, Switzerland)
Tambone V, Campanozzi LL, Di Mauro L, Fenato F, Travaini G +7 more
Plain English This study looks at how new technologies in healthcare, like Artificial Intelligence and data analytics, are changing how doctors work and the ethics behind their practices. It found that as these technologies become more important, medical professionals need to rethink their responsibilities and the Medical Code of Ethics to ensure patient care remains focused on people and not just profit or ideology. The proposed solution is a new clinical method that combines human touch with advanced technology, making healthcare more effective and ethically sound.
Who this helps: This benefits patients and healthcare professionals by ensuring that care remains ethical and personalized.
Dependence and clinical fragility in hematopoietic stem cell transplant and CAR-T therapy: a retrospective study.
2025
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
Cioce M, Raponi M, Visintini C, Pascucci D, Botti S +9 more
Plain English This study looked at 498 patients receiving two types of cancer treatments: hematopoietic stem cell transplants and CAR-T therapy. Researchers found that patients undergoing CAR-T therapy had a higher chance of falling and clinical complications during their hospital stay, with allogeneic transplant patients also struggling with lower functional independence. This is important because it shows that these therapies can lead to serious challenges that may require more careful planning and support for patients.
Who this helps: This helps patients undergoing cancer treatments and their healthcare providers.
Assessing the Impact of Waiting Time on Triage Color Code Assignment and One-Year Mortality in the Emergency Department: A Causal Mediation Analysis.
2025
Health science reports
Nurchis MC, Covino M, Savoia C, Altamura G, Cambieri A +7 more
Plain English Researchers looked at how waiting times in the emergency room influence the chances of surviving for one year, especially for patients with less urgent issues. They studied over 56,000 patients and found that while triage color codes (used to prioritize patients based on how quickly they need care) are important predictors of one-year mortality, waiting times don't significantly change those outcomes. In particular, older patients and those with yellow triage codes had a higher risk of dying within a year, but reducing waiting times for less urgent patients may not make a difference in their long-term survival.
Who this helps: This research benefits emergency department staff and hospital administrators working to improve patient triage and outcomes.
Exploring the post-mortem interval through blood biochemistry: a preliminary case series study and review of the literature.
2025
International journal of legal medicine
Grassi VM, Ciasca G, Vetrugno G, Urbani A, Pascali VL +1 more
Plain English This study looked at blood samples from patients who died in hospitals to find out how certain chemicals in the blood change over time after death. Researchers found that two specific chemicals, phosphokinase (CPK) and lactodehydrogenase (LDH), significantly increased after death, with levels rising in a consistent way. Understanding these changes could help determine how long someone has been dead, which is important for medical and legal reasons.
Who this helps: This helps doctors and forensic teams who need accurate information about the time of death.
Transcranial Doppler and Color-Coded Doppler Use for Brain Death Determination in Adult Patients: A Pictorial Essay.
2024
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine
Deana C, Biasucci DG, Aspide R, Brasil S, Vergano M +9 more
Plain English This study looked at the use of Transcranial Doppler (TCD) imaging to help determine if an adult patient has experienced brain death by checking if blood flow to the brain has stopped. The findings show that while TCD can be useful, it requires skilled operators and can be inaccurate due to limitations such as not being able to see all blood vessels clearly. Understanding how to effectively use TCD and a similar method called color-coded Doppler is important for ensuring accurate diagnosis in critical care situations.
Who this helps: This helps doctors in intensive care units make better decisions about patient care.
Predictive Power of Dependence and Clinical-Social Fragility Index and Risk of Fall in Hospitalized Adult Patients: A Case-Control Study.
2024
Journal of patient safety
Cioce M, Grassi S, Borrelli I, Grassi VM, Ghisellini R +9 more
Plain English This study looked at how certain scores related to a patient's independence and social fragility can predict the risk of falls in hospitalized patients. Researchers found that patients who fell in the hospital had significantly higher scores on various fragility scales both when they were admitted (for example, a BRASS scale score of 10.2 compared to 7.0 for those who didn't fall) and when they were discharged. This matters because it helps identify patients at higher risk for falling, allowing hospitals to take action to prevent these accidents.
Who this helps: This helps patients and healthcare providers by improving fall prevention strategies in hospitals.
Hand hygiene, knowledge and training motivational drives: findings from a survey in a university hospital.
2024
Frontiers in public health
Corbo MI, Wachocka M, Pozzi M, Cioce M, Di Donato M +10 more
Plain English This study examined how well healthcare workers at a large university hospital in Italy understand and follow hand hygiene practices. Out of 6,749 workers, only 542 responded to a survey, revealing an average knowledge level of 74% about hand hygiene, with notable gaps in understanding proper techniques. This is important because good hand hygiene is crucial for preventing infections in patients, and improving training can lead to better compliance and safer healthcare environments.
Who this helps: Patients and healthcare workers.
The potential role of interleukin-6 in the association between inflammation and cognitive performance in obstructive sleep apnea.
2024
Brain, behavior, & immunity - health
Fernandes M, Spanetta M, Vetrugno G, Nuccetelli M, Placidi F +7 more
Plain English This study looked at the relationship between a substance called interleukin-6 (IL-6), inflammation, and thinking skills in patients with severe obstructive sleep apnea (OSA). Researchers found that patients with severe OSA had much higher levels of IL-6 (7.38) compared to healthy individuals (2.20) and also showed poorer cognitive performance, measured by the Montreal Cognitive Assessment (27.00 vs. 30.00). These findings suggest that increased IL-6 levels may be linked to brain damage from low oxygen during sleep, which leads to cognitive problems.
Who this helps: This helps patients with obstructive sleep apnea and their doctors.
Blood alcohol concentration and road accidents: Underestimation due to time of the arrival to the emergency department (ED) or delay in blood sampling. A 4-Year Retrospective Study in Rome.
2023
Medicine, science, and the law
Cittadini F, De Giovanni N, Aulino G, Lentini G, Vetrugno G +2 more
Plain English This study looked at how delays in blood testing in the emergency department might lead to underestimating the blood alcohol levels of drivers involved in accidents. Out of 398 patients, 107 had blood alcohol concentrations above 0.05 g/L, and 86 of these were even higher than 0.5 g/L, especially at night and on weekends. These findings highlight the need for better timing in blood alcohol tests to accurately assess DUI cases and help implement strategies to prevent drunk driving.
Who this helps: This helps patients involved in accidents and the healthcare professionals treating them.
BNT162b2 COVID-19 Vaccine Safety among Healthcare Workers of a Tertiary Hospital in Italy.
2023
Vaccines
Beccia F, Regazzi L, Marziali E, Beccia V, Pascucci D +3 more
Plain English This study looked at the safety of the BNT162b2 COVID-19 vaccine among healthcare workers in a large hospital in Italy. They analyzed 2,428 reports of side effects following the first vaccine dose and found that most symptoms were mild, short-lived, and non-serious. However, some side effects were reported more often than expected, particularly fatigue and pain at the injection site, which often appeared together in groups of symptoms.
Who this helps: This information benefits healthcare workers and helps guide public health decisions about vaccination safety.
Analysis of Medico-Legal Complaint Data: A Retrospective Study of Three Large Italian University Hospitals.
2023
Healthcare (Basel, Switzerland)
Di Fazio N, Scopetti M, Delogu G, La Russa R, Foti F +8 more
Plain English This study looked at legal complaints related to medical care at three large hospitals in Italy from 2013 to 2020, analyzing a total of 2,098 cases. Out of these, only 779 cases (about 37%) could be clearly categorized for detailed analysis, showing that recognizing and classifying issues in hospital care can help identify areas needing improvement. By using specific indicators, hospitals can better assess their care quality over time and make targeted changes.
Who this helps: This research benefits hospital administrators and healthcare policy makers looking to improve patient care.
Co-administration of SARS-CoV-2 and influenza vaccines in healthcare workers: Results of two vaccination campaigns in a large teaching hospital in Rome.
2023
Human vaccines & immunotherapeutics
Pascucci D, Lontano A, Regazzi L, Marziali E, Nurchis MC +5 more
Plain English This study looked at how healthcare workers in a large hospital in Rome accepted getting both COVID-19 and influenza vaccines at the same time during two vaccination campaigns. In the 2022/2023 campaign, the number of workers receiving both vaccines together rose by 38% compared to the previous year, with the greatest increases seen among resident doctors (47%) and physicians (44%). This matters because getting vaccinated for both illnesses at once can help keep healthcare workers and patients safe from serious respiratory infections.
Who this helps: This benefits healthcare workers and their patients.
A Fifteen-Year Survey for Orthopedic Malpractice Claims in the Criminal Court of Rome.
2023
Healthcare (Basel, Switzerland)
Bernardinangeli C, Giannace C, Cerciello S, Grassi VM, Lodise M +2 more
Plain English This study looked at malpractice claims against orthopedic doctors in Rome from 2000 to 2015. Out of nearly 5,000 cases examined, only 3.93% resulted in doctors being convicted, while over half (53%) were dismissed and 14.2% ended in acquittals. This finding highlights a significant imbalance in how these cases are handled and suggests that doctors face unfair pressure, which may affect their practice and patient care.
Who this helps: This benefits doctors and ultimately their patients by promoting a better doctor-patient relationship.
Comparative Impact Analysis of Low-Deductible Insurance Versus In-house Hospital Assumption of Risk and Management on Medical Malpractice Claims.
2023
Journal of patient safety
Vetrugno G, Grassi S, Foti F, Siodambro C, Grassi VM +11 more
Plain English This study looked at how hospitals handle malpractice claims when they take on more financial risk versus when insurance companies manage those claims. Researchers at a hospital in Rome analyzed over 2,000 claims from 2007 to 2021 and discovered that when hospitals took on more responsibility for these risks, the number of malpractice claims dropped by about 3.7% each year, and the increase in payouts was slower than the national average. This matters because it shows that hospitals can improve patient safety and manage costs better when they are more involved in the claims process.
Who this helps: This benefits hospitals, patients, and insurers by improving safety and potentially lowering costs.
Medical Professional Liability in Obstetrics and Gynecology: A Pilot Study of Criminal Proceedings in the Public Prosecutor's Office at the Court of Rome.
2023
Healthcare (Basel, Switzerland)
Bergamin E, Fiorillo A, Grassi VM, Lodise M, Vetrugno G +1 more
Plain English This study looked at criminal charges against doctors in the fields of obstetrics and gynecology in Rome from 2000 to 2014. Researchers found that there were 727 cases, with most charges related to patient injuries and wrongful deaths. The rise in prosecutions shows increasing legal scrutiny on these specialties, making it essential for new regulations to protect both doctors and patients.
Who this helps: This benefits doctors and healthcare providers in obstetrics and gynecology.
How to manage falls in hospitalized patients: A single center experience in allogeneic stem cell transplantation setting.
2022
Medicine
Cioce M, Lohmeyer FM, Botti S, Rostagno E, Orlando L +7 more
Plain English This study looked at falls among patients undergoing stem cell transplants in a hospital. Out of 214 patients, there were 15 falls involving 11 patients, leading to a fall rate of 2.32 falls per patient. The research found that falls often happened at night, and were commonly caused by diuretic and antihypertensive medications, along with patients being weak on their feet. To reduce falls, the researchers created a checklist of 16 safety measures.
Who this helps: This helps patients undergoing stem cell transplants and the healthcare professionals caring for them.
Microbiological screening tests for SARS-CoV-2 in the first hour since the hospital admission: A reliable tool for enhancing the safety of pediatric care.
2022
Frontiers in pediatrics
Vetrugno G, Grassi S, Clemente F, Cazzato F, Rossi V +9 more
Plain English This study looked at how effective quick tests for SARS-CoV-2 are in protecting kids admitted to the Emergency Department from catching COVID-19 while in the hospital. Over two periods, researchers tested 1,313 children using two different testing methods and found that almost all results (1,576 out of a total of 1,617 tests) were negative, with no reported cases of hospital-acquired infections. This is important because it shows that using rapid tests can help keep children safe from COVID-19 while they are being treated in the hospital.
Who this helps: This helps pediatric patients and healthcare providers in hospitals.
Trend in 167 cases of minors witnessing violence: The role played by COVID-19 pandemic.
2022
Frontiers in pediatrics
Focardi M, Grassi S, Raddi S, Rosati ME, Cazzato F +6 more
Plain English This study examined 167 cases of minors who witnessed violence over four years at a hospital in Florence, Italy. The researchers found that 69% of the victims had been previously abused, and the majority of the violence was domestic, with 79% of cases occurring at home. Importantly, the study revealed that the COVID-19 pandemic did not significantly impact the number of cases of domestic, physical, psychological, or sexual abuse.
Who this helps: This information benefits healthcare providers and policymakers focused on protecting vulnerable children from violence.
Risk of Infection and Duration of Protection after the Booster Dose of the Anti-SARS-CoV-2 Vaccine BNT162b2 among Healthcare Workers in a Large Teaching Hospital in Italy: Results of an Observational Study.
2022
Vaccines
Pascucci D, Grossi A, Lontano A, Marziali E, Nurchis MC +9 more
Plain English This study looked at how long the booster dose of the Pfizer-BioNTech COVID-19 vaccine protects healthcare workers in a large hospital in Rome from infections. It found that the risk of becoming infected increased over time, with only 2.5% infected at four weeks, 17% at twelve weeks, and 40% at twenty-four weeks after the booster. This is important because it shows that booster protection declines and highlights the importance of ongoing monitoring to ensure continued safety among healthcare workers.
Who this helps: This helps healthcare workers and their employers understand the need for regular vaccination updates.
Effect of Lockdowns on Hospital Staff in a COVID Center: A Retrospective Observational Study.
2022
Vaccines
Vetrugno G, Sanguinetti M, Murri R, Sali M, Marchetti S +22 more
Plain English This study looked at how lockdowns in Italy during the COVID-19 pandemic affected hospital staff at Policlinico A. Gemelli. It found that the positivity rate of COVID-19 infections among staff dropped significantly after the first lockdown ended, decreasing by 9.3% (from a statistical perspective, this was a highly significant change). However, infections rose again after the lockdown, but a second lockdown led to another decrease in the positivity rate by 3.9% after its end. This matters because it shows that lockdowns were effective in protecting hospital workers and ensuring they could care for both COVID and non-COVID patients safely.
Who this helps: This helps healthcare workers and patients receiving care in hospitals.
Malpractice Claims and Incident Reporting: Two Faces of the Same Coin?
2022
International journal of environmental research and public health
Vetrugno G, Foti F, Grassi VM, De-Giorgio F, Cambieri A +7 more
Plain English This study looked at two ways to track problems in healthcare: malpractice claims and incident reports. Over nearly eight years, researchers found 843 malpractice claims and 1,919 incident reports, with claims slightly decreasing and reports increasing during 2020-2021. The findings highlight that while both systems show patient harm, they capture different types of events, which is important for improving patient safety.
Who this helps: This helps patients and healthcare providers by improving safety and care quality.
Flu and COVID-19 Vaccination: What Happens to the Flu Shot When the Campaigns Overlap? Experience from a Large Italian Research Hospital.
2022
Vaccines
Pascucci D, Nurchis MC, Lontano A, Marziali E, Vetrugno G +5 more
Plain English This study examined flu vaccination rates among healthcare workers at a large hospital in Italy during the COVID-19 pandemic. The findings revealed a 50% drop in flu vaccination coverage over the past two years, with actual rates at 24% compared to an expected 38.5%. This decline may be linked to concerns about getting both the flu and COVID-19 vaccines at the same time and fears about potential side effects.
Who this helps: This benefits healthcare workers and helps protect patient safety by ensuring they are vaccinated against influenza.
COVID-19 Vaccination Campaign among the Health Workers of Fondazione Policlinico Universitario Agostino Gemelli IRCCS: A Cost-Benefit Analysis.
2022
International journal of environmental research and public health
Nurchis MC, Lontano A, Pascucci D, Sapienza M, Marziali E +8 more
Plain English This study looked at the costs and benefits of the COVID-19 vaccination campaign for over 5,000 healthcare workers at Fondazione Policlinico Universitario Agostino Gemelli IRCCS, focusing on those who received the Pfizer-BioNTech vaccine. It found that the campaign cost nearly 2.2 million euros but created benefits worth over 10.3 million euros, leading to a benefit-to-cost ratio of 4.66, meaning for every euro spent, there were almost 5 euros gained in benefits. This is important because it highlights that investing in vaccinations for health workers not only protects them but also provides substantial economic benefits to society.
Who this helps: Patients and healthcare workers benefit from increased protection and better health outcomes.
COVID-19 Seroprevalence among Healthcare Workers of a Large COVID-19 Hospital in Rome Reveals Strengths and Limits of Two Different Serological Tests.
2021
International journal of environmental research and public health
Vetrugno G, La Milia DI, D'Ambrosio F, Di Pumpo M, Pastorino R +22 more
Plain English This study looked at the presence of COVID-19 antibodies in healthcare workers at a major hospital in Rome to see how effective two different antibody tests were. Out of nearly 5,000 healthcare workers, 3.66% tested positive using a quick test, while only 1.19% tested positive with a standard blood test, showing the quick test was less accurate overall. These findings highlight the strengths and weaknesses of the two tests, emphasizing that neither is reliable for diagnosing active COVID-19 infections.
Who this helps: This benefits healthcare workers and doctors by informing them about the accuracy of tests used to monitor COVID-19 exposure.
Is COVID-19 a Real Incentive for Flu Vaccination? Let the Numbers Speak for Themselves.
2021
Vaccines
Di Pumpo M, Vetrugno G, Pascucci D, Carini E, Beccia V +8 more
Plain English This study looked at how the COVID-19 pandemic influenced healthcare workers to get the flu vaccine. It found that flu vaccination rates among these workers jumped from 24.19% in the 2019/2020 flu season to 54.56% in the 2020/2021 season, which is a significant increase. This matters because it highlights how the pandemic motivated more healthcare professionals to protect themselves and their patients through vaccination.
Who this helps: Patients and healthcare workers.
Gemelli decision tree Algorithm to Predict the need for home monitoring or hospitalization of confirmed and unconfirmed COVID-19 patients (GAP-Covid19): preliminary results from a retrospective cohort study.
2021
European review for medical and pharmacological sciences
Vetrugno G, Laurenti P, Franceschi F, Foti F, D'Ambrosio F +18 more
Plain English Researchers created an easy-to-use computer tool that helps doctors decide if COVID-19 patients need to stay at home or go to the hospital. They studied 198 patients and found that 14% had mild symptoms, while 22% were critically ill. The tool uses specific health measurements to quickly assess a patient's condition, making it easier for doctors to provide the right care.
Who this helps: This helps doctors and healthcare providers manage COVID-19 patients more effectively.
Use of post-mortem chest computed tomography in Covid-19 pneumonia.
2021
Forensic science international
De-Giorgio F, Cittadini F, Cina A, Cavarretta E, Biondi-Zoccai G +4 more
Plain English This study looked at using chest scans after death to identify COVID-19 pneumonia, especially in elderly people from long-term care homes. Out of 24 deceased individuals, 13 were from a care facility, and 9 of these (69%) died from severe COVID-19 pneumonia. The scans showed specific lung issues, such as "ground-glass opacities," in all cases, making this method a reliable way to confirm COVID-19 pneumonia without needing time-consuming lab tests.
Who this helps: This helps doctors and healthcare professionals in accurately identifying COVID-19 as the cause of death in patients, particularly the elderly in care facilities.
SARS-CoV-2 Antigen Detection to Expand Testing Capacity for COVID-19: Results from a Hospital Emergency Department Testing Site.
2021
Diagnostics (Basel, Switzerland)
Menchinelli G, De Angelis G, Cacaci M, Liotti FM, Candelli M +6 more
Plain English This study looked at how using rapid antigen tests for COVID-19 in an emergency department could help improve testing speed and reduce the need for more complex tests. Researchers found that 12.4% of patients in the COVID-19 area tested positive for the virus using the antigen tests, which helped avoid unnecessary RT-PCR tests for over 1,800 patients who tested negative in the non-COVID-19 area. This approach saved time and resources, ensuring that patients suspected of having COVID-19 received quicker results.
Who this helps: Patients being tested for COVID-19 in emergency rooms.
Dying "from" or "with" COVID-19 during the Pandemic: Medico-Legal Issues According to a Population Perspective.
2021
International journal of environmental research and public health
De-Giorgio F, Grassi VM, Bergamin E, Cina A, Del Nonno F +7 more
Plain English This study looked at the causes of death in patients who tested positive for COVID-19 in two Italian nursing homes. Out of nine patients, four died because of COVID-19-related issues, while five died from carbon monoxide poisoning with no direct influence from the virus. Understanding the accurate causes of death helps clarify how COVID-19 is reported and managed in healthcare.
Who this helps: This helps doctors and public health officials improve death reporting and treatment strategies for patients.
Evaluation of the Effectiveness and Safety of the BNT162b2 COVID-19 Vaccine in the Vaccination Campaign among the Health Workers of Fondazione Policlinico Universitario Agostino Gemelli IRCCS.
2021
International journal of environmental research and public health
Pascucci D, Nurchis MC, Sapienza M, Castrini F, Beccia F +12 more
Plain English This study evaluated the effectiveness and safety of the BNT162b2 COVID-19 vaccine among health workers at a hospital in Italy. Out of 6,649 health workers, 5,162 received the vaccine, resulting in only 14 COVID-19 cases after full vaccination, compared to 45 cases among those who weren’t vaccinated, showing the vaccine is 91.5% effective. This is important because it demonstrates that vaccinating health workers can significantly reduce COVID-19 infections, helping to keep patients and staff safer in hospitals.
Who this helps: Patients and health workers.
Management of Medico-Legal Risks in Digital Health Era: A Scoping Review.
2021
Frontiers in medicine
Oliva A, Grassi S, Vetrugno G, Rossi R, Della Morte G +2 more
Plain English This research paper looks at the legal and ethical challenges that arise from using artificial intelligence (AI) in healthcare, especially during the COVID-19 pandemic. It found that storing patient health data is necessary for AI to work effectively, but this raises concerns about privacy and potential legal issues, like medical malpractice. Educating doctors on how to manage these risks can help them follow regulations better and lower the chances of legal problems.
Who this helps: This helps patients and healthcare professionals.
Missed linkage to care for patients who screened positive for Hepatitis C in a tertiary care centre: Results of the Telepass project.
2021
Journal of viral hepatitis
Ponziani FR, Santopaolo F, Siciliano M, De Belvis AG, Tortora A +12 more
Plain English The study looked at how effective a recall system, called the 'Telepass' project, was in connecting patients who tested positive for Hepatitis C (HCV) to necessary medical care. Out of over 12,000 patients tested, 224 were found to be positive for HCV, and more than half of those hadn’t received follow-up testing. The recall efforts reached 123 of these patients, successfully linking 26 to care, with 10 starting treatment. This is important because it shows that structured outreach can help identify and treat people with chronic Hepatitis C, contributing to efforts to eliminate the virus in Italy by 2030.
Who this helps: This helps patients with Hepatitis C get the care they need.
Sudden nasal bleeding and brodifacoum: A case of accidental exposure or attempted homicide?
2020
Legal medicine (Tokyo, Japan)
Foti F, Sica S, Alma E, De Cristofaro R, Mores N +1 more
Plain English This research paper discusses a case of a 50-year-old man who experienced severe nosebleeds and was found to have high levels of a chemical called brodifacoum in his system, a substance often used as a rodent killer. Despite various treatments, the bleeding continued, and it took extensive testing and an investigation to identify how he was exposed to this dangerous anticoagulant. This case highlights the importance of collaboration among medical professionals and law enforcement when dealing with unusual poisoning cases.
Who this helps: This information benefits doctors, emergency responders, and public health officials.
Liability of Health Care Professionals and Institutions During COVID-19 Pandemic in Italy: Symposium Proceedings and Position Statement.
2020
Journal of patient safety
Oliva A, Caputo M, Grassi S, Vetrugno G, Marazza M +6 more
Plain English This study focused on the legal responsibilities of healthcare professionals and institutions in Italy during the COVID-19 pandemic. Experts discussed key issues, such as the liability of hospitals for staff infections due to inadequate protective gear and for patients who caught COVID-19 in medical facilities. They propose limiting legal liability only to cases of serious misconduct and suggest a system to provide government compensation for those infected.
Who this helps: This benefits healthcare workers, patients, and hospital managers by clarifying legal responsibilities during health crises.