L I Anishchenko studies how well the medication Revelise works for patients suffering from ischemic stroke, which happens when a blood vessel supplying blood to the brain gets blocked. Their research investigates the safety and effectiveness of this treatment by looking at real-life cases, aiming to better understand how older patients and those with other health conditions respond to the medication. This work is critical for improving recovery outcomes for stroke patients and informing doctors about the best treatment options available.
Key findings
In a study involving 2,202 patients, 49.9% had good outcomes upon discharge after treatment with Revelise.
The percentage of patients with good outcomes improved to 66.4% after 90 days.
The study demonstrated that Revelise can significantly reduce disabilities related to strokes, even in older patients and those with additional health issues.
Frequently asked questions
Does Dr. Anishchenko study stroke treatments?
Yes, Dr. Anishchenko studies the treatment of ischemic strokes using the medication Revelise.
What were the outcomes of the study on Revelise?
The study found that nearly 50% of patients had good outcomes shortly after treatment, which increased to over 66% after three months.
Is Dr. Anishchenko's research relevant for older stroke patients?
Yes, Dr. Anishchenko's research specifically highlights the effectiveness of Revelise in older patients as well as those with other health problems.
Publications in plain English
[Thrombolytic Therapy for Ischemic Stroke with Revelise: Results of a Two-Year Follow-Up in the International PRIMA Study].
2025
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
Shamalov NA, Khasanova DR, Marchenko SV, Soldatov MA, Azarova AG +46 more
Plain English This study looked at how well and safely Revelise (alteplase), a medication for treating ischemic stroke (IS), works in real-life situations. It involved 2,202 patients, mostly around 68 years old, and found that nearly half (49.9%) of them had good outcomes when discharged, rising to 66.4% after 90 days. The results showed that Revelise effectively reduces stroke-related disabilities, even in older patients and those with other health issues.
Who this helps: This benefits patients who suffer from ischemic strokes and the doctors treating them.
[Clinical and epidemiological characteristics of stroke in the Khanty-Mansi autonomous region].
2013
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
Lebedev IA, Gil'vanov VA, Akinina SA, Anishchenko LI, Sokolova AA
Plain English This study looked at stroke cases in the Khanty-Mansi region of Russia and found that people there experience strokes less frequently and have a better chance of survival compared to the rest of the country. Specifically, the yearly rate of new strokes was higher in men, although they had fewer risk factors. Overall, the types of strokes were similar to those seen nationally, but there were notable differences in how men and women were affected.
Who this helps: This helps patients by providing insights into regional stroke characteristics that can improve treatment and prevention strategies.
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
Lebedev IA, Gilvanov VA, Akinina SA, Anishchenko LI
Plain English This study looked at how weather conditions, like changes in temperature and atmospheric pressure, are linked to the occurrence of strokes in Khanty-Mansiysk over a five-year period. Researchers found that days with large swings in temperature led to more strokes, particularly noting that the highest numbers occurred in December, April, May, and July. Understanding these connections can help improve stroke prevention strategies during certain weather conditions.
Who this helps: This helps patients at risk of stroke and healthcare providers working on prevention strategies.
[Disturbances of blood lipid content after acute disorders of brain blood flow].
2011
Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova
Ivanova NE, Lebedev IA, Akinina SA, Anishchenko LI, Koltsov VV +3 more
Plain English This study looked at blood fat levels in 421 patients who had heart-related issues like strokes between 2004 and 2008. Researchers found that most patients had higher-than-normal levels of fats in their blood, especially low-density lipoproteins, which were elevated in 63.5% of cases. This is important because managing these blood fat levels can help prevent more serious heart issues in patients recovering from brain problems.
Who this helps: This helps patients recovering from strokes and their doctors in managing their health.
Plain English This study looked at the rates of cerebral stroke in the Khanty-Mansiysk region of Russia and compared them to national averages. It found that the region has lower rates of stroke and early deaths from stroke than the rest of the country, with men experiencing strokes more than women. However, some risk factors for stroke, like high blood pressure and smoking, were found to be more common in this region than in other parts of Russia.
Who this helps: This information helps doctors and health officials focus on preventing stroke, especially in men and by addressing specific local risk factors.