L Pascolini

School of Psychology, University of East Anglia.

22 publications 2008 – 2025 ORCID

What does L Pascolini research?

L Pascolini studies the treatment of cow's milk allergies using a method called oral desensitization. This technique involves gradually exposing patients to small amounts of cow's milk to help their bodies become less reactive to it over time. The research evaluates how well a blood test, known as the Basophil Activation Test (BAT), can track changes in patients’ immune responses during this treatment. This is important for understanding whether patients are actually becoming tolerant to cow's milk, which can improve their quality of life.

Key findings

  • In a pilot study, the Basophil Activation Test showed a reduction in allergy antibodies (IgE) in three male patients undergoing oral desensitization, indicating improved tolerance.
  • The same study revealed an increase in a different type of antibody (IgG4), suggesting a favorable immune response as patients became tolerant to cow's milk.
  • Blood tests indicated significant reductions in allergic reactions to milk proteins during the treatment phase.

Frequently asked questions

Does Dr. Pascolini study cow's milk allergies?
Yes, Dr. Pascolini specifically studies cow's milk allergies and how to treat them through oral desensitization.
What treatments has Dr. Pascolini researched?
Dr. Pascolini has researched oral desensitization as a treatment method for cow's milk allergies.
Is Dr. Pascolini's work relevant to patients with food allergies?
Yes, Dr. Pascolini's work is highly relevant as it focuses on methods to help patients with cow's milk allergies develop tolerance.

Publications in plain English

Observed nonhumanoid robot actions induce vicarious agency when perceived as social actors, not as objects.

2025

Journal of experimental psychology. Human perception and performance

Pascolini L, Bayliss AP, Le AH, Wyer NA

Plain English
This study looked at how people perceive toy robots when they interact with them in a social way. Researchers found that when participants played a game with a robot, they felt more connected to its actions and underestimated the time between what the robot did and the outcome, showing a sense of shared intention. Specifically, this "sense of connection" was stronger in social interactions versus mechanical ones, suggesting that even simple robots can be seen as having agency if the context is right. Who this helps: This benefits designers of social robots and can improve human-robot interactions in various settings, like healthcare or education.

PubMed

The emergence of task-relevant representations in a nonlinear decision-making task.

2023

Neurobiology of learning and memory

Menghi N, Silvestrin F, Pascolini L, Penny W

Plain English
This study looked at how people make decisions when faced with tasks that have multiple important factors. Researchers found that participants who performed well on these tasks could better understand and represent the key features of the situation. Specifically, those who did well started recognizing important information about 700 milliseconds after they saw the stimulus, which helped them make better decisions. Who this helps: This helps patients who struggle with decision-making by improving techniques for therapy and training.

PubMed

Words of agency: Executed and observed vocal actions induce a temporal binding effect.

2021

Journal of experimental psychology. Human perception and performance

Pascolini L, Stephenson LJ, Bayliss AP, Wyer NA

Plain English
This study looked at how people feel a sense of control over the sounds they make with their voices. Researchers conducted experiments showing that when people vocalize and then hear the sound, they think less time has passed than it actually has. They found that simply watching someone else vocalize can also create this feeling of time compression, but only if you can see them doing it. Who this helps: This research benefits psychologists and mental health professionals studying human perception and social interactions.

PubMed

A kind of magic: Enhanced detection of pantomimed grasps in professional magicians.

2020

Quarterly journal of experimental psychology (2006)

Quarona D, Koul A, Ansuini C, Pascolini L, Cavallo A +1 more

Plain English
This study examined how professional magicians identify hand movements that mimic reaching for imagined objects, called pantomimed grasps. Researchers tested 17 magicians and 17 non-magicians by showing them videos of these movements and found that magicians were better at distinguishing the pantomimed gestures from real ones. Specifically, while both groups performed equally well with real grasps, magicians had a noticeable edge in recognizing the imagined ones. Who this helps: This benefits magicians and potentially influences how performers and audiences understand deception in tricks.

PubMed

Cross-reactivity and Tolerability of Ertapenem in Patients With IgE-Mediated Hypersensitivity to β-Lactams.

2016

Journal of investigational allergology & clinical immunology

Buonomo A, Pascolini L, Rizzi A, Aruanno A, Pecora V +6 more

Plain English
This study looked at whether a drug called ertapenem could be safely given to patients who are allergic to certain antibiotics known as β-lactams. Out of 49 patients tested, 35 were able to safely receive ertapenem after showing negative allergy tests. This is important because it suggests that many patients with β-lactam allergies may not need to avoid carbapenem antibiotics, which can be critical for treating infections. Who this helps: This benefits patients with β-lactam allergies who require antibiotic treatment.

PubMed

A Case of Heparin Allergy With Good Tolerability to Fondaparinux During Pregnancy.

2015

Journal of investigational allergology & clinical immunology

Buonomo A, Nucera E, De Carolis S, De Stefano V, Pascolini L +3 more

PubMed

Occupational contact dermatitis from carbapenems.

2015

Cutis

Colagiovanni A, Feliciani C, Fania L, Pascolini L, Buonomo A +2 more

PubMed

Utility of Basophil Activation Test for monitoring the acquisition of clinical tolerance after oral desensitization to cow's milk: Pilot study.

2015

United European gastroenterology journal

Nucera E, Pecora V, Buonomo A, Rizzi A, Aruanno A +8 more

Plain English
This study looked at how well a blood test, called the Basophil Activation Test (BAT), can track if people with cow's milk allergies become tolerant to milk after a special treatment called oral desensitization. In three male patients who went through this treatment, the results showed that while their specific allergy antibodies (IgE) went down, a different type of antibody (IgG4) went up, and the blood tests indicated that their allergic reactions to milk proteins were significantly reduced. This matters because it suggests that the BAT can effectively monitor the progress of treatment and the development of tolerance in food allergy patients. Who this helps: This helps patients with cow's milk allergies and their doctors.

PubMed

Cross-reactivity and tolerability of cephalosporins in patients with cell-mediated allergy to penicillins.

2014

Journal of investigational allergology & clinical immunology

Buonomo A, Nucera E, Pecora V, Rizzi A, Aruanno A +4 more

Plain English
This study looked at how patients with a specific allergy to penicillins might react to a group of antibiotics called cephalosporins. Out of 97 patients tested, 17 showed allergic reactions to some cephalosporins, primarily cephalexin, while most were able to tolerate these drugs without any serious issues. The findings revealed that about 10.9% of patients might have cross-reactivity with first-generation cephalosporins, but this was only 1.1% for third-generation cephalosporins, making patch tests and careful monitoring important for safely prescribing these antibiotics. Who this helps: This helps patients with penicillin allergies who may need alternative antibiotics.

PubMed

Italian study on buckwheat allergy: prevalence and clinical features of buckwheat-sensitized patients in Italy.

2013

International journal of immunopathology and pharmacology

Badiu I, Olivieri E, Montagni M, Guida G, Mietta S +21 more

Plain English
This study looked at how common buckwheat allergy is among patients in Italy and found that 3.6% of those tested were sensitized to buckwheat, with higher rates in the Northern regions (4.5%) compared to Central (2.2%) and Southern (2.8%) areas. The research included nearly 2,000 patients from 18 allergy clinics and revealed that buckwheat is becoming a more recognized allergen in Italy, especially in the North. Understanding the prevalence of this allergy matters because it helps to better identify and manage food allergies in the population. Who this helps: Patients with buckwheat allergies and their doctors.

PubMed

The clinical meaning of positive latex sIgE in patients with food/pollen adverse reactions.

2012

International journal of immunopathology and pharmacology

Nucera E, Rizzi A, Buonomo A, De Pasquale T, Pecora V +7 more

Plain English
This study looked at people who have allergies to both latex and certain foods, specifically focusing on a condition called "Latex-fruit Syndrome." Researchers examined 51 patients and found that 34 had clear allergic reactions to latex and fruits/vegetables, while 17 had allergy symptoms to fruits and vegetables but not to latex. Notably, all tests for latex allergies came back positive for those in the first group, while only two from the second group showed any reaction. This distinction is important because it helps doctors understand which patients are truly allergic to latex and may need specific treatments or management strategies. Who this helps: Patients with latex and food allergies can benefit from clearer diagnoses and better management.

PubMed

Profilin desensitization in two patients with plant-derived food allergy.

2012

International journal of immunopathology and pharmacology

Nucera E, Aruanno A, Rizzi A, Buonomo A, Pecora V +4 more

Plain English
This study looked at two patients who were allergic to certain foods derived from plants and how a treatment called sublingual desensitization (SLIT) worked for them. After undergoing this treatment, both patients could eat previously avoided foods without allergic reactions, and their allergy-related antibody levels decreased. This is important because it shows that SLIT can effectively help people with specific plant-based food allergies manage their diets more freely. Who this helps: This benefits patients with plant-derived food allergies.

PubMed

Weight loss: only anorexia?

2011

Internal and emergency medicine

Colagiovanni A, Pascolini L, Buonomo A, Nucera E, Schiavino D

PubMed

Tolerability of aztreonam in patients with cell-mediated allergy to β-lactams.

2011

International archives of allergy and immunology

Buonomo A, Nucera E, De Pasquale T, Pecora V, Lombardo C +7 more

Plain English
This study looked at how well patients with a specific type of penicillin allergy tolerate a drug called aztreonam. Researchers tested 78 patients, finding that while they experienced some allergic reactions to other penicillin-like drugs, none of the patients reacted negatively to aztreonam when it was tested on them. This is important because it shows that aztreonam can be safely used by patients who are allergic to other β-lactam antibiotics, helping to expand their treatment options. Who this helps: This benefits patients with β-lactam allergies who need effective antibiotic treatments.

PubMed

A case of IgE-mediated allergy and cell-mediated allergy to Seaprose-S in the same patient.

2011

Contact dermatitis

De Pasquale T, Buonomo A, Pecora V, Colagiovanni A, Aruanno A +5 more

PubMed

'Empty sella syndrome': a case of a patient with sodium succinate hydrocortisone allergy.

2011

European journal of endocrinology

Nucera E, Lombardo C, Aruanno A, Colagiovanni A, Buonomo A +7 more

Plain English
This study looked at a woman with 'empty sella syndrome' who had allergic reactions to a specific steroid medication called sodium succinate hydrocortisone. After testing, it was found that she was allergic to this particular drug but could safely use other steroid medications. This is important because it helps identify safe treatment options for patients with similar allergies, allowing them to receive necessary care without risking an allergic reaction. Who this helps: This helps patients with allergies to specific steroid medications.

PubMed

Delayed hypersensitivity to heparin in a patient with cancer: fondaparinux may be safe but needs to be tested.

2010

Contact dermatitis

Colagiovanni A, Rizzi A, Buonomo A, De Pasquale T, Pecora V +5 more

PubMed

Allergic and non-allergic drug hypersensitivity reactions in children.

2010

International journal of immunopathology and pharmacology

Buonomo A, Altomonte G, De Pasquale T, Lombardo C, Pecora V +8 more

Plain English
This study looked at how children react to certain medications, specifically those who have had negative responses to drugs. Researchers examined 278 children and found that only six were diagnosed with a true drug allergy, while most reactions were found to be non-allergic. The study showed that using premedication helped prevent adverse reactions in many cases. Who this helps: This information assists doctors in safely prescribing medications to children with a history of drug reactions.

PubMed

Sublingual immunotherapy with natural rubber latex: a case report with 8-year follow-up.

2010

Contact dermatitis

Pecora V, Aruanno A, Buonuomo A, De Pasquale T, Colagiovanni A +7 more

PubMed

Cross-reactivity and tolerability of imipenem in patients with delayed-type, cell-mediated hypersensitivity to beta-lactams.

2009

Allergy

Schiavino D, Nucera E, Lombardo C, Decinti M, Pascolini L +3 more

Plain English
This study looked at how well patients with a specific type of allergy to beta-lactam antibiotics (the kind found in penicillin) tolerated a related antibiotic called imipenem-cilastatin. They found that out of 73 patients tested, only 4 showed a possible reaction to imipenem, resulting in a low cross-reactivity rate of 5.5%. This is important because it suggests that many patients with this type of allergy can safely use imipenem-cilastatin, which gives doctors another option for treating infections. Who this helps: Patients with delayed-type allergies to beta-lactams who need alternative antibiotics.

PubMed

Sublingual immunotherapy with venom for patients with Hymenoptera venom allergy.

2009

The Journal of allergy and clinical immunology

Patriarca G, Nucera E, Roncallo C, Aruanno A, Lombardo C +5 more

PubMed

Sublingual desensitization in patients with wasp venom allergy: preliminary results.

2008

International journal of immunopathology and pharmacology

Patriarca G, Nucera E, Roncallo C, Aruanno A, Lombardo C +5 more

Plain English
This study looked at two methods for treating people allergic to wasp venom: one was sublingual immunotherapy (SLIT), where patients placed venom drops under their tongue, and the other was subcutaneous immunotherapy (SCIT), where patients received venom injections. Both groups had similar overall results, with 9.5% of the SLIT patients and 15% of the SCIT patients experiencing side effects. Importantly, during treatment, patients who had severe past reactions to wasp stings were less likely to have serious reactions when stung again. Who this helps: This benefits patients with wasp venom allergies, particularly those who have experienced severe reactions in the past.

PubMed

Publication data sourced from PubMed . Plain-English summaries generated by AI. Not medical advice.