Dr. Bittencourt studies how gadolinium, a dye used in magnetic resonance imaging (MRI), affects patients and how it can be used safely. His research addresses concerns about gadolinium accumulating in the body and potentially causing harm over time. He examines the preferences and practices of radiologists regarding different types of gadolinium, particularly macrocyclic agents, which are preferred for their safety. By working with experts, he aims to establish guidelines to ensure that gadolinium is used in the least harmful ways possible, especially in vulnerable populations like pregnant women.
Key findings
Experts agree that gadolinium is safe for acute reactions, with serious kidney problems being rare.
Radiologists recommend using macrocyclic agents over linear agents to reduce risks.
Experts suggest smaller doses of gadolinium to prevent accumulation in the body.
There is a consensus not to use gadolinium in pregnant patients to avoid potential risks.
Frequently asked questions
Does Dr. Bittencourt study the effects of gadolinium?
Yes, he focuses on the safe use of gadolinium as a contrast agent in MRI scans.
What recommendations has Dr. Bittencourt made regarding gadolinium use?
He recommends using macrocyclic gadolinium agents and smaller doses to minimize health risks.
Is Dr. Bittencourt's work relevant to patients undergoing MRI?
Yes, his research helps inform safer practices for patients receiving MRI scans with gadolinium.
Can gadolinium pose risks for pregnant patients?
Dr. Bittencourt advises against using gadolinium in pregnant patients due to potential risks.
What should doctors know about gadolinium according to Dr. Bittencourt?
Doctors need better training on gadolinium risks to ensure they use only necessary amounts and the safest types.
Publications in plain English
Real-World Performance of MRI-TRUS Fusion Biopsy in a Canadian Tertiary Centre: What Drives a Positive Diagnosis?
2026
Canadian Association of Radiologists journal = Journal l'Association canadienne des radiologistes
Strieder de Oliveira G, Bittencourt LK, Chang SD, Dias AB
Use of Dynamic Magnetic Resonance of the Urethra in Surgical Planning of Vesicourethral Anastomotic Stenosis Urethroplasty.
2026
International braz j urol : official journal of the Brazilian Society of Urology
Fiedler G, Cavalcanti AG, Bittencourt LK, Goldman SM
Plain English This study looked at how useful a new type of MRI, called dynamic Magnetic Resonance of the Urethra (d-MRU), is for planning surgery for men developing a narrow urethra after prostate surgery. The researchers compared 48 men who had their urethra examined with this new MRI technique to another group using a standard method, finding that the d-MRU showed better results in preserving blood vessels (94.4% vs. 63.3%). While there wasn't a big difference in the rates of re-narrowing after surgery (5.6% for d-MRU vs. 16.7% for the other method), the dynamic MRU closely matched what doctors observed during surgery.
Who this helps: This benefits patients undergoing surgery for urethral strictures after prostate removal.
Improving Prostate MRI: Lessons Learned from the American College of Radiology's Prostate MR Image Quality Improvement Collaborative.
2026
Radiographics : a review publication of the Radiological Society of North America, Inc
Purysko AS, Garcia-Tomkins K, Zacharias-Andrews K, Bittencourt LK, Giganti F +7 more
Plain English This study focused on improving the quality of MRI images used for diagnosing and managing prostate cancer. The American College of Radiology worked with 14 organizations to identify key areas to enhance image quality, such as better preparation for patients and training for staff. Changes made resulted in higher quality images and more efficient processes, leading to better job satisfaction for the staff involved.
Who this helps: This benefits patients by ensuring more accurate prostate cancer diagnoses and treatment planning.
Free-breathing qRF-MRF with pilot tone respiratory motion navigator for T, T, T*, and off-resonance mapping of the human body at 3 T.
2025
Magma (New York, N.Y.)
Kretzler ME, Huang SS, Sun JEP, Bittencourt LK, Chen Y +2 more
Plain English This study looked at a new way to perform MRI scans of the abdomen without requiring patients to hold their breath. Researchers tested this method on ten healthy volunteers and found that it produced similar results to traditional MRI techniques, which often take longer and can be affected by patient movement. Specifically, the new approach provided accurate measurements of tissue properties like T1 and T2 times, which are important for diagnosing conditions in organs like the liver and spleen.
Who this helps: This benefits patients who need quicker and more comfortable MRI scans without the stress of holding their breath.
Prostate Imaging for Recurrence Reporting System Made Easy: A Case-Based Review of Prostate Cancer Local Recurrence on Magnetic Resonance Imaging.
2025
Seminars in ultrasound, CT, and MR
Antunes PM, Sabaneeff N, Correia ETO, Bittencourt LK
Plain English This study looked at how well a new scoring system, called PI-RR, helps doctors use MRI to find local recurrence of prostate cancer after treatment. The authors reviewed cases and found that while MRI is good for spotting local recurrences, it struggles with detecting very small tumors in lymph nodes. Understanding how to read these MRI results is crucial because it helps ensure that patients get the right follow-up care and treatment if their cancer returns.
Who this helps: This helps patients and doctors manage prostate cancer recurrence more effectively.
Requirements for AI Development and Reporting for MRI Prostate Cancer Detection in Biopsy-Naive Men: PI-RADS Steering Committee, Version 1.0.
2025
Radiology
Turkbey B, Huisman H, Fedorov A, Macura KJ, Margolis DJ +10 more
Plain English This document outlines important guidelines for creating and reporting artificial intelligence (AI) systems that help detect significant prostate cancer using MRI scans in men who have not yet undergone a biopsy. The findings indicate that these AI systems should achieve a cancer detection rate between 40% and 70% for high-risk lesions and must perform as well as or better than human experts. Establishing clear requirements for data quality and performance is crucial for ensuring these AI tools are effective and trustworthy in clinical settings.
Who this helps: This benefits doctors, patients at risk for prostate cancer, and the medical community by improving cancer detection methods.
Quantitative assessment of bladder tissue properties using magnetic resonance fingerprinting: a pilot feasibility study in healthy volunteers.
2025
Radiologia brasileira
Correia ETO, Badreddine J, Boyacioglu R, Kretzler ME, Griswold MA +5 more
Plain English This study explored a new imaging technique called magnetic resonance fingerprinting (MRF) to measure properties of the bladder in healthy women before and after urination. The researchers found that the average time it takes for the bladder tissue to recover after voiding (T1) decreased by about 6% from 1,575 milliseconds to 1,476 milliseconds, while the T2 recovery time changed slightly. These findings are significant because they establish a baseline for future research on bladder conditions, helping doctors better understand bladder health and diseases.
Who this helps: Patients with bladder disorders and their doctors.
Multiparametric MR Urethrography: Dynamic Comprehensive Evaluation of the Male Urethra.
2025
Radiographics : a review publication of the Radiological Society of North America, Inc
Henz Concatto N, Schuch A, de Oliveira Caetano T, Fávero Prietto Dos Santos J, Morzoletto Pedrollo I +4 more
Plain English This research explored the use of a special MRI technique, called multiparametric MR urethrography, to better understand urethral diseases in men, like strictures and injuries, which can seriously affect how they urinate. The study highlighted that traditional imaging methods are often not enough since they can't clearly show surrounding tissues, while MR urethrography provides a detailed view of both the urethra and its nearby structures. This matters because better imaging can help diagnose and treat urethral conditions more effectively, improving men's quality of life.
Who this helps: This benefits male patients dealing with urethral diseases and their healthcare providers.
Population-Specific Radiomics From Biparametric Magnetic Resonance Imaging Improves Prostate Cancer Risk Stratification in African American Men.
2025
JU open plus
Midya A, Tirumani S, Bittencourt LK, Azamat S, Balakrishnan S +6 more
Plain English This study focused on how prostate cancer appears on MRI scans in African American men compared to White men. Researchers analyzed data from 149 men and found that the MRI features associated with clinically significant prostate cancer were notably different between the two groups. Specifically, the models used for African American men showed an accuracy rate of 84% in identifying significant cancer, compared to just 57% for a general population model, highlighting the importance of tailored approaches for different populations.
Who this helps: This helps African American men at risk for prostate cancer and their doctors in making better treatment decisions.
Multi-scanner repeatability and reproducibility of qRF-MRF breath-held and free-breathing with pilot tone in the abdomen.
2025
Magma (New York, N.Y.)
Kretzler ME, Sun JEP, de Oliveira Correia ET, Bittencourt LK, Flask CA +2 more
Plain English This study looked at a new MRI technique called quantitative RF Magnetic Resonance Fingerprinting (qRF-MRF) to see how consistently it works when scanning the abdomen, especially the liver. Researchers tested this new method on 8 healthy volunteers using two different MRI machines and found that the results for key measurements, T1, T2, and T2*, were reliable, meaning this technique can produce similar images across different machines and sessions. This is important because it allows doctors to trust the images for diagnosing and treating patients better.
Who this helps: This helps patients and doctors by providing reliable imaging results for liver assessments.
A rare case of IgG4-related sclerosing cholangitis followed by rapid subsequent diagnosis of cholangiocarcinoma.
2025
Journal of liver cancer
Hong G, Hussain A, Correia ETO, Shalaby A, Bittencourt LK +3 more
Plain English This study looked at a rare condition called IgG4-related sclerosing cholangitis (IgG4-SC) in a 62-year-old man, who was diagnosed with it and later developed a type of bile duct cancer called cholangiocarcinoma. The case shows how difficult it can be to diagnose and manage IgG4-SC because it can mimic other serious conditions, and the patient faced risks from treatments that suppress the immune system. The research highlights the potential of a new treatment option, inebilizumab, which might improve care for people with this condition.
Who this helps: This helps patients with IgG4-related diseases and their doctors.
Artificial intelligence applications in prostate cancer.
2024
Prostate cancer and prostatic diseases
Baydoun A, Jia AY, Zaorsky NG, Kashani R, Rao S +7 more
Plain English This research paper looks at how artificial intelligence (AI) is being used in the diagnosis and treatment of prostate cancer. Researchers found that AI tools can improve accuracy in analyzing tissue samples and medical images, as well as in predicting how patients will respond to treatment. For instance, several AI systems have been validated using data from thousands of patients, leading to better personalized treatment options.
Who this helps: This helps patients by improving their treatment options and outcomes.
Assessing the Potential of a Deep Learning Tool to Improve Fracture Detection by Radiologists and Emergency Physicians on Extremity Radiographs.
2024
Academic radiology
Fu T, Viswanathan V, Attia A, Zerbib-Attal E, Kosaraju V +4 more
Plain English This study examined how well a deep learning tool could help doctors spot fractures in limb X-rays. Researchers found that the tool was very effective, achieving a 98.6% accuracy rate, and it improved doctors' ability to detect fractures; for example, sensitivity (how well it correctly identified fractures) improved from 86.5% to 95.5% with the tool's help. This is important because it not only makes diagnosing fractures more accurate but also speeds up the process by reducing reading time by over 7 seconds per exam, which is especially beneficial for busy emergency room doctors.
Who this helps: This helps patients and doctors, particularly emergency physicians and non-specialist radiologists.
PI-RADS Upgrading Rules: Impact on Prostate Cancer Detection and Biopsy Avoidance of MRI-Directed Diagnostic Pathways.
2024
AJR. American journal of roentgenology
de Oliveira Correia ET, Purysko AS, Paranhos BM, Shoag JE, Padhani AR +1 more
Plain English Researchers studied how certain rules, known as PI-RADS upgrading rules, can improve the detection of significant prostate cancer while potentially reducing unnecessary biopsies in patients without known prostate cancer. They looked at data from 716 men who had prostate MRIs and found that adhering to these rules helped keep the detection of clinically significant cancer rates stable without increasing the number of unnecessary biopsies. Specifically, using these rules showed a better balance between identifying cancer and avoiding unnecessary procedures, with a maximum avoidance of 25% of biopsies.
Who this helps: This benefits patients at risk for prostate cancer by reducing the number of unnecessary biopsies and improving cancer detection methods.
Plain English This study looked at the prostate glands of different animals—dogs, rabbits, and mice—to find the best model for researching prostate diseases, using human anatomy as a reference. Researchers found that dogs were the best animal model, showing a prostate structure similar to humans, while rabbits and mice had varying levels of visibility for their prostate glands when using different imaging techniques. Specifically, canine ultrasound imaging was the most effective for understanding the gland, as dogs have a similar morphology to humans but with some differences, which is critical for improving medical device development and disease treatment.
Who this helps: This benefits researchers and doctors working on prostate disease and developing related medical technologies.
Radiographics : a review publication of the Radiological Society of North America, Inc
Neme GL, Guimarães CTS, Dantas PP, Santana DDB, Yamauchi FI +4 more
Plain English This study looked at how imaging techniques, like ultrasound and MRI, are used after surgery to understand and manage endometriosis, a condition that affects 10%-15% of women of childbearing age and causes chronic pain and infertility. The research highlighted the importance of knowing what normal recovery looks like on scans to help doctors tell the difference between normal healing and any remaining or recurring endometriosis, which can help in better patient care. This matters because accurate imaging can lead to more effective treatment and improved outcomes for women suffering from this condition.
Who this helps: This helps patients with endometriosis and their doctors by improving post-surgery evaluations and care.
Emerging and anticipated innovations in prostate cancer MRI and their impact on patient care.
2024
Abdominal radiology (New York)
Correia ETO, Baydoun A, Li Q, Costa DN, Bittencourt LK
Plain English This study looked at new and upcoming improvements in MRI technology for prostate cancer, which affects over 3 million men in the U.S. each year. Researchers found that advancements in MRI techniques, including the use of artificial intelligence and new imaging methods, can significantly enhance the accuracy of diagnosing and treating prostate cancer. These innovations are expected to lead to better patient outcomes and more precise treatment options.
Who this helps: This benefits patients with prostate cancer by providing more effective diagnosis and treatment options.
Porto-sinusoidal Vascular Disease and Portal Hypertension.
2024
Clinics in liver disease
Noble S, Linz M, Correia E, Shalaby A, Bittencourt LK +1 more
Plain English This study focused on porto-sinusoidal vascular disease (PSVD), which occurs when a patient has high blood pressure in the liver without having liver cirrhosis. Researchers found that PSVD is a common cause of portal hypertension, making up less than 10% of cases in Western countries but affecting up to 48% of cases in India. Understanding PSVD is important because it helps identify specific liver problems and can guide better treatment options.
Who this helps: This helps patients with liver issues and doctors treating them.
Variability of Prostate MRI Charges Among U.S. Hospital-Based Facilities.
2023
AJR. American journal of roentgenology
Brant A, Wu X, Prunty M, Margolis DJA, Bittencourt LK +2 more
Plain English This study looked at how much U.S. hospitals charge for prostate MRI scans over ten years. Researchers found that the average charge was $4,419, but patients faced charges as low as $593 and as high as $15,150, revealing a huge price difference between hospitals. It’s important because this variability can lead to unexpected expenses for patients, highlighting the need for better transparency in medical pricing.
Who this helps: Patients seeking prostate MRIs.
Evaluating the Downstream Revenues of a Self-Pay Bi-Parametric Prostate MRI Program.
2023
Urology
Parikh KD, Declouette B, Chen M, Rao S, Smith DA +4 more
Plain English This study looked at how a self-pay prostate MRI program affects healthcare costs and services for patients from 2017 to 2020. Researchers found that on average, each patient generated about $520 in additional healthcare revenue after their MRI, with those who had a detected issue and underwent surgery contributing the most at around $1,974 each. The findings indicate that this program could increase access to prostate cancer screenings while being financially viable for healthcare providers.
Who this helps: This benefits patients seeking prostate cancer screening and doctors providing urological care.
Automated prostate multi-regional segmentation in magnetic resonance using fully convolutional neural networks.
2023
European radiology
Jimenez-Pastor A, Lopez-Gonzalez R, Fos-Guarinos B, Garcia-Castro F, Wittenberg M +12 more
Plain English This study focused on using advanced computer technology, specifically a type of artificial intelligence known as a convolutional neural network (CNN), to automatically divide prostate MRI images into key areas that are important for assessing prostate cancer. The results showed that the CNN model could accurately identify different regions of the prostate, achieving scores of 0.88 for the prostate gland and 0.85 for the central zone, which suggests it works well across various machines and settings. This matters because accurate image segmentation can help doctors evaluate prostate cancer more effectively, leading to better patient care.
Who this helps: Patients undergoing prostate cancer evaluation and their doctors.
Imaging in urethral stricture disease: an educational review of current techniques with a focus on MRI.
2023
Abdominal radiology (New York)
Harris D, Zhou C, Girardot J, Kidron A, Gupta S +2 more
Plain English This study looked at different imaging techniques used to diagnose a condition called urethral stricture disease, which happens when the urethra is narrowed and can block urine flow. Researchers reviewed various methods, especially focusing on magnetic resonance urethrography (MRU), which has become important because it gives clearer images and can show details about surrounding tissues. They found that MRU can be very helpful in accurately assessing the condition, but some of its newer applications aren't widely used yet.
Who this helps: This helps doctors and patients dealing with urethral stricture disease.
PI-RADS 3 lesions: a critical review and discussion of how to improve management.
2023
Abdominal radiology (New York)
Nicola R, Bittencourt LK
Plain English This study looked at how to better manage PI-RADS 3 lesions, which are identified as potentially concerning prostate abnormalities. Researchers found that considering factors like Prostate Specific Antigen Density (PSAD), patient age, and tumor size can help make clearer decisions about whether a biopsy is necessary. Improving this management is important because it can lead to better patient outcomes and avoid unnecessary procedures.
Who this helps: Patients with prostate concerns and their doctors.
Magnetic resonance fingerprinting based comprehensive quantification of T1 and T2 values of the background prostatic peripheral zone: Correlation with clinical and demographic features.
2023
European journal of radiology
de Oliveira Correia ET, Qiao PL, Griswold MA, Chen Y, Bittencourt LK
Plain English This study examined the quantities of T1 and T2 values in the prostate, specifically in the peripheral zone, using a technique called magnetic resonance fingerprinting in 124 patients. The researchers found that the average T1 value was 1941 milliseconds and the average T2 value was 88 milliseconds across the entire gland. They also discovered that T1 and T2 values were linked to the width of the prostate and varied among patients with different imaging scores, which helps in understanding prostate health.
Who this helps: This helps patients and doctors by providing better insights into prostate conditions and helping in the assessment of prostate health.
Impact of Magnetic Resonance Imaging Targeting on Pathologic Upgrading and Downgrading at Prostatectomy: A Systematic Review and Meta-analysis.
2023
European urology oncology
Weinstein IC, Wu X, Hill A, Brennan D, Omil-Lima D +14 more
Plain English This study looked at how different methods of prostate biopsy, specifically MRI-targeted and systematic biopsies, affect the accuracy of cancer grading after surgery. It found that MRI-targeted biopsies were less likely to upgrade patients' cancer grades (27% compared to 42% with systematic biopsies) but led to more cases being downgraded (19% versus 11%). Understanding these differences is important because it helps doctors make better treatment decisions and reduces the risk of overdiagnosing or overtreating low-grade cancers.
Who this helps: This benefits patients undergoing prostate cancer treatment and their doctors.
Novel radiomic analysis on bi-parametric MRI for characterizing differences between MR non-visible and visible clinically significant prostate cancer.
2023
European journal of radiology open
Li L, Shiradkar R, Tirumani SH, Bittencourt LK, Fu P +9 more
Plain English This study looked at how certain imaging features in prostate cancer can help identify tumors that are not visible on MRI but are still clinically significant. Researchers found that specific radiomic features from a special type of MRI (known as bi-parametric MRI) could accurately distinguish between visible and non-visible prostate cancer. The best analysis correctly identified 10 out of 14 non-visible tumors with a high accuracy level (82%).
Who this helps: This research helps doctors better identify and treat clinically significant prostate cancer in patients where tumors are not easily visible on traditional MRI.
Deep infiltrating endometriosis: cine magnetic resonance imaging in the evaluation of uterine contractility.
2023
Radiologia brasileira
Soares DM, Bittencourt LK, Lopes FPPL, de Oliveira MAP
Plain English This study evaluated how well the uterus functions in women with deep infiltrating endometriosis by using advanced imaging techniques to see its contractions. Researchers looked at 43 women and found that those with endometriosis had more frequent contractions of the uterus compared to those without, especially during certain phases of their menstrual cycle, but these differences weren't always significant. However, women with a related condition called adenomyosis had much fewer contractions in the critical phase for fertility, which could affect their chances of conceiving.
Who this helps: This research can benefit women with endometriosis and adenomyosis trying to understand their fertility issues.
Delta radiomic patterns on serial bi-parametric MRI are associated with pathologic upgrading in prostate cancer patients on active surveillance: preliminary findings.
2023
Frontiers in oncology
Midya A, Hiremath A, Huber J, Sankar Viswanathan V, Omil-Lima D +6 more
Plain English This study looked at how changes in MRI scans of prostate cancer (PCa) patients on active surveillance relate to changes in their pathology over time. Researchers monitored 50 patients and found that the method used to assess changes (called delta radiomics) was particularly effective: it identified upgrades in cancer severity in 84% of cases, showing stronger connections than traditional methods like PSA levels or initial biopsy results. This is important because it could lead to better monitoring strategies that help doctors identify when a patient's cancer is becoming more aggressive.
Who this helps: This benefits prostate cancer patients under active surveillance and their doctors.
Spatiotemporal knowledge teacher-student reinforcement learning to detect liver tumors without contrast agents.
2023
Medical image analysis
Xu C, Song Y, Zhang D, Bittencourt LK, Tirumani SH +1 more
Plain English This study focused on a new method to detect liver tumors without using contrast agents, which are often risky for patients. The researchers developed a technique called SKT-RL that improved the accuracy of tumor detection using regular MRI scans, achieving at least a 4% increase in precision over six other advanced methods. This is significant because it makes liver cancer screening safer and more efficient by eliminating the need for potentially harmful contrast agents.
Who this helps: This helps patients undergoing liver cancer screening.
Risk-based MRI-directed diagnostic pathway outperforms non-risk-based pathways in suspected prostate cancer biopsy-naïve men: a large cohort validation study.
2022
European radiology
Bittencourt LK, Guricova K, Zucker I, Durieux JC, Schoots IG
Plain English This study looked at different methods for diagnosing prostate cancer in men who had never had a biopsy and were at risk for the disease. The researchers tested a "risk-based" MRI pathway, which avoided unnecessary biopsies in lower-risk patients, leading to a 19.2% reduction in the need for biopsies and a detection rate of clinically significant cancer of 51.7%. This approach helps to accurately identify serious cases while minimizing the chance of diagnosing less harmful cancers, making it a better choice for doctors and patients alike.
Who this helps: This benefits men at risk for prostate cancer and their healthcare providers.
Multicenter Repeatability and Reproducibility of MR Fingerprinting in Phantoms and in Prostatic Tissue.
2022
Magnetic resonance in medicine
Lo WC, Bittencourt LK, Panda A, Jiang Y, Tokuda J +7 more
Plain English This study looked at how consistently a new MRI technique called MR fingerprinting (MRF) can measure certain properties (T1 and T2 values) in prostate tissue across different hospitals and MRI machines. Researchers found that the T1 values varied by less than 4.9% and T2 values by less than 8.1% when comparing machines from different locations, showing that the measurements are reliable. This is important because it means doctors can trust these MRI results to be accurate and consistent, regardless of where the scan is done.
Who this helps: This benefits patients with prostate conditions by providing more reliable MRI assessments.
PI-RADS Committee Position on MRI Without Contrast Medium in Biopsy-Naive Men With Suspected Prostate Cancer: Narrative Review.
2021
AJR. American journal of roentgenology
Schoots IG, Barentsz JO, Bittencourt LK, Haider MA, Macura KJ +10 more
Plain English This paper discusses the growing need for prostate MRIs and the challenges in providing these scans due to limited access and qualified personnel. It explores the possibility of performing MRIs without a special contrast dye and emphasizes the importance of maintaining high-quality imaging and expert analysis. The authors call for more studies to determine who can safely have MRIs without contrast, as this could improve access and diagnostic processes for men suspected of prostate cancer.
Who this helps: This helps patients, especially men at risk for prostate cancer, by potentially making diagnostic MRIs more accessible.
Prostate Magnetic Resonance Imaging for Local Recurrence Reporting (PI-RR): International Consensus -based Guidelines on Multiparametric Magnetic Resonance Imaging for Prostate Cancer Recurrence after Radiation Therapy and Radical Prostatectomy.
2021
European urology oncology
Panebianco V, Villeirs G, Weinreb JC, Turkbey BI, Margolis DJ +12 more
Plain English This research developed guidelines for using MRI to detect local recurrence of prostate cancer in men who have previously undergone treatment like radiation therapy or surgery. The new system, called PI-RR, categorizes MRI results into five levels based on the likelihood of cancer returning, ranging from very low (PI-RR 1) to very high (PI-RR 5). This standardization aims to improve accuracy and consistency in reporting, which is important for better treatment planning and patient outcomes.
Who this helps: This helps patients with prostate cancer and their doctors by providing clearer guidelines for monitoring cancer recurrence.
Seamless Integration of Artificial Intelligence Into the Clinical Environment: Our Experience With a Novel Pneumothorax Detection Artificial Intelligence Algorithm.
2021
Journal of the American College of Radiology : JACR
Pierce JD, Rosipko B, Youngblood L, Gilkeson RC, Gupta A +1 more
Plain English This study looked at how to effectively use a new artificial intelligence (AI) tool that helps detect pneumothoraces, which are pockets of air that can collapse the lung, during chest X-rays. The researchers successfully integrated this AI system with their existing radiology processes, improving how quickly they could identify positive cases. Their experience can guide other hospitals and clinics in adopting similar AI technologies to enhance patient care.
Who this helps: This helps doctors and patients by providing faster and more accurate diagnoses for lung conditions.
Guimaraes CTS, Sauer LJ, Romano RFT, Pacheco EO, Bittencourt LK
Plain English This research focused on using MRI to help detect and understand benign diseases of the prostate, which are common but often overlooked. The study found that conditions like benign prostatic hyperplasia and prostatitis are much more common than rare benign tumors, with prostatic cysts being the most frequent abnormality detected, sometimes causing symptoms due to infections. Using MRI effectively gives doctors better insights into these conditions, allowing for improved diagnosis and treatment.
Who this helps: This benefits patients with prostate issues and their doctors.
Variability of the Positive Predictive Value of PI-RADS for Prostate MRI across 26 Centers: Experience of the Society of Abdominal Radiology Prostate Cancer Disease-focused Panel.
Plain English This study looked at how effective the Prostate Imaging Reporting and Data System (PI-RADS) is at identifying significant prostate cancer across 26 different imaging centers. They found that the overall chance of accurately detecting high-grade cancer (with a Gleason score of 3+4 or higher) was 35% for men with a PI-RADS score of 3 and 49% for those with a score of 4, with variability in results among different centers. These findings highlight that while PI-RADS is widely used, its reliability can differ significantly, which matters for making informed decisions about patient care.
Who this helps: This helps patients and doctors by providing clarity on the effectiveness of prostate MRI in diagnosing cancer.
Quality Comparison of 3 Tesla multiparametric MRI of the prostate using a flexible surface receiver coil versus conventional surface coil plus endorectal coil setup.
2020
Abdominal radiology (New York)
Ullrich T, Kohli MD, Ohliger MA, Magudia K, Arora SS +6 more
Plain English This study looked at two different ways of doing MRI scans of the prostate: one using a flexible surface coil (FSC) and the other using a traditional endorectal coil (ERC). The researchers found that while individual radiologists had their preferences, overall, there was no strong preference for one method over the other. However, the FSC was preferred for certain images and the ERC provided better signal clarity for detecting tumors.
Who this helps: This research helps doctors determine the best MRI method for prostate exams, benefiting patients who need accurate imaging.
Practical recommendations for the safe use of gadolinium in magnetic resonance imaging: a Delphi expert panel study.
2020
Radiologia brasileira
Baroni RH, Bauab T, Bittencourt LK, D'Ippolito G, Goldman SM +5 more
Plain English Doctors who perform MRI scans use gadolinium contrast dye to get better images, but experts were concerned that this dye might accumulate in the brain and body over time. This study surveyed 10 experienced radiologists in Brazil about their practices with different types of gadolinium dyes to figure out the safest way to use them.
The experts agreed that gadolinium is safe for acute reactions and serious kidney problems are rare, but they preferred using certain types of gadolinium (macrocyclic agents) over others and recommended using smaller doses to reduce the buildup in the body. Most experts also agreed not to use it in pregnant patients.
The main takeaway is that doctors need better training to understand gadolinium risks so they use only the amount necessary and choose the safest types available.
Intra- and interreader reproducibility of PI-RADSv2: A multireader study.
2019
Journal of magnetic resonance imaging : JMRI
Smith CP, Harmon SA, Barrett T, Bittencourt LK, Law YM +10 more
Plain English This study examined how consistently different doctors interpret MRI scans of the prostate using the PI-RADSv2 scoring system, which helps identify potential cancerous lesions. Researchers found that individual doctors (intrareader) usually agreed moderately well on their assessments, with scores ranging from 0.43 to 0.67. However, when comparing scores between different doctors (interreader), the agreement was generally poor, with a score of only 0.24. This highlights the importance of better training for healthcare providers in interpreting prostate MRIs to ensure more reliable results.
Who this helps: This benefits doctors and patients, especially those undergoing prostate imaging for cancer detection.
Plain English This study examined how cine MRI can be used to assess the movements of the uterus, which are important for conception and maintaining a healthy pregnancy. It found that cine MRI is effective in detecting problems with uterine contractions that can lead to infertility, helping healthcare providers identify patients who may benefit from targeted treatments. Understanding and diagnosing these issues can improve the chances of successful pregnancies, especially for those struggling with infertility.
Who this helps: This research helps patients facing infertility, particularly those with issues related to uterine function.
Fully automated convolutional neural network-based affine algorithm improves liver registration and lesion co-localization on hepatobiliary phase T1-weighted MR images.
2019
European radiology experimental
Hasenstab KA, Cunha GM, Higaki A, Ichikawa S, Wang K +8 more
Plain English This study looked at how well an automated computer program can align liver images from different scans compared to manual methods. The researchers found that the automated method improved the accuracy of liver image overlap and correlation, achieving a mean overlap of 0.88 for scans taken at the same time and 0.81 for scans taken at different times, which is significantly better than manual methods. This improvement helps doctors better locate liver lesions, making it easier to diagnose and treat liver conditions.
Who this helps: This benefits patients who need accurate liver imaging, as well as doctors diagnosing liver diseases.
Schlemmer HP, Bittencourt LK, D'Anastasi M, Domingues R, Khong PL +5 more
Plain English This research paper looks at the challenges faced in cancer imaging, which is crucial for diagnosing and treating cancer effectively. It highlights that developing countries struggle with a lack of imaging equipment and trained radiologists, while advanced countries have enough equipment but lack specialists trained to use it effectively. Addressing these issues is important because without proper imaging, patients may not receive the best possible care.
Who this helps: This information benefits patients and healthcare providers in both developing and advanced countries.
Pancreatic fat deposition is increased and related to beta-cell function in women with familial partial lipodystrophy.
2018
Diabetology & metabolic syndrome
Godoy-Matos AF, Valerio CM, Moreira RO, Momesso DP, Bittencourt LK
Plain English This study examined the fat stored in the pancreas and how well the pancreas functions in women with familial partial lipodystrophy (FPLD) compared to healthy individuals. Researchers found that women with FPLD had significantly more pancreatic fat (5.26 vs. 4.08) and higher waist-to-hip ratios, which suggests a link between excess fat and reduced ability of the pancreas to function properly. This matters because understanding the relationship between pancreatic fat and function can help manage diabetes and related conditions in patients with FPLD.
Who this helps: This helps patients with familial partial lipodystrophy and their doctors.