M Lynn Shay

University of Delaware, Department of Physics and Astronomy, Newark, Delaware, USA.

50 publications 2010 – 2026 ORCID

What does M Lynn Shay research?

M Lynn Shay studies the use of CRISPR, a powerful gene-editing technology, to alter genes that affect cholesterol levels in the body. Specifically, she has investigated how inactivating the PCSK9 gene, which plays a key role in regulating cholesterol production, can lead to dramatic reductions in cholesterol levels. By delivering this gene-editing treatment via small fat particles directly into the bloodstream, her research aims to provide a one-time solution for patients suffering from high cholesterol, potentially eliminating the need for lifelong medication.

Key findings

  • A single CRISPR gene-editing treatment lowered cholesterol levels in monkeys by about 60%.
  • This cholesterol reduction lasted for at least 8 months without any additional treatment.
  • The research indicates the feasibility of using gene editing as a long-term treatment for heart disease patients.

Frequently asked questions

Does Dr. Shay study high cholesterol?
Yes, Dr. Shay focuses on high cholesterol and its genetic factors.
What treatments has Dr. Shay researched?
Dr. Shay has researched a gene-editing treatment using CRISPR to disable the PCSK9 gene in order to lower cholesterol levels.
Is Dr. Shay's work relevant to heart disease patients?
Absolutely, her research explores innovative treatments that could provide long-term solutions for heart disease related to high cholesterol.

Publications in plain English

Factors controlling the statistics of magnetic reconnection in magnetohydrodynamic turbulence.

2026

Physical review. E

Khan MB, Shay MA, Oughton S, Matthaeus WH, Haggerty CC +7 more

Plain English
This study looked at how magnetic reconnection events happen within strong magnetic turbulence, using computer simulations. Researchers found that the rate of these reconnection events is much higher during turbulent conditions than previously thought, showing a strong link between the reconnection rates and the overall strength of the magnetic fields around them. This finding is important because it suggests that magnetic reconnection could significantly impact energy loss in space environments, such as those found around stars and planets. Who this helps: This benefits scientists studying space weather and astrophysics.

PubMed

Flow Crossover and Parallel Outflow during Collisionless Magnetic Reconnection.

2026

Physical review letters

Pianpanit T, Malakit K, Prapan P, Ruffolo D, Pongkitiwanichakul P +3 more

Plain English
This study looked at how charged particles (ions and electrons) behave during a process called magnetic reconnection, which happens in space plasmas. Researchers used computer simulations and found that particles from opposite sides of a divide mix and flow together in unexpected ways, particularly noting that electrons tend to flow parallel to the magnetic field rather than crossing it directly. This behavior is significant because it helps us understand how energy moves in space environments, such as near Earth, which can affect satellites and other technologies. Who this helps: This helps scientists and engineers working on space missions and satellite technology.

PubMed

Outstanding Questions and Future Research on Magnetic Reconnection.

2025

Space science reviews

Nakamura R, Burch JL, Birn J, Chen LJ, Graham DB +20 more

Plain English
This article discusses the unresolved issues related to magnetic reconnection in plasma, which is a state of matter found in stars and other celestial bodies. It points out that while new measurements and simulations have provided insight, there are still key questions about how magnetic reconnection starts, how different scales interact during the process, and how it energizes particles. Understanding these factors is important because they impact our knowledge of space weather and its effects on technology on Earth. Who this helps: This research benefits scientists studying space phenomena and its impacts on technology.

PubMed

Detection of Large Guide Field Electron-Only Reconnection in a Filamentary Current Sheet Immersed in a Large-Scale Magnetopause Reconnection Exhaust.

2025

Physical review letters

Pyakurel PS, Phan TD, Øieroset M, Drake JF, Shay MA +12 more

Plain English
This research looked at a specific phenomenon in space where the behavior of electric currents changes dramatically in a section of the magnetosphere known as a magnetopause. The study found that when electrons and ions move in different directions—referred to as electron-only reconnection—one section showed a strong electron flow opposite to the ion flow. Of particular significance, the four spacecraft used for the study recorded different signals, highlighting that this reconnection can vary greatly over short distances and times. This matters because understanding these processes can help improve our knowledge of space weather and its effects on technology on Earth. Who this helps: This helps scientists and engineers working on protecting technology from space weather effects.

PubMed

SARS-CoV-2 RNA-binding protein suppresses extracellular miRNA release.

2025

RNA biology

Mun H, Shin CH, Fei Q, Giraldo AEL, Choi KM +19 more

Plain English
This research studied how a specific protein from the SARS-CoV-2 virus affects the body's response to infections. The scientists found that a viral protein called Nsp9 binds to a small RNA molecule called let-7b, which normally helps activate the immune response. By inhibiting let-7b, Nsp9 prevents the body from using its antiviral defenses, which can worsen COVID-19 infections. Who this helps: This research benefits doctors and scientists looking for better treatments for COVID-19 patients.

PubMed

Simulation Models for Exploring Magnetic Reconnection.

2025

Space science reviews

Shay M, Adhikari S, Beesho N, Birn J, Büchner J +20 more

Plain English
This research paper reviews different computer simulation methods used to study magnetic reconnection, which is a process that involves changes in magnetic fields in plasma. It discusses various techniques, such as magnetohydrodynamics and kinetic particle models, and shows how these methods help scientists understand the behavior and effects of magnetic reconnection. These insights are crucial because they can improve our understanding of space weather and its impact on technology and safety on Earth. Who this helps: This helps scientists and researchers studying plasma physics and space weather.

PubMed

Palliative Medicine and End of Life Care Between Races in an Academic Intensive Care Unit.

2024

Journal of intensive care medicine

Fassas S, King D, Shay M, Schockett E, Yamane D +1 more

Plain English
This study examined how different racial groups use palliative medicine (PM) in the intensive care unit (ICU) at a hospital, focusing on patients who passed away. Researchers looked at 571 patients from two different time periods and found that while PM use increased overall, Black/African-American patients were less likely to have "do not resuscitate" (DNR) orders compared to White patients (about 57% less likely), indicating a racial disparity in end-of-life choices. This matters because ensuring all patients have equal access to palliative care can improve the quality of life for individuals facing serious illnesses. Who this helps: This helps patients and families making end-of-life decisions.

PubMed

Transfer learning predicts species-specific drug interactions in emerging pathogens.

2024

bioRxiv : the preprint server for biology

Chung CH, Chang DC, Rhoads NM, Shay MR, Srinivasan K +3 more

Plain English
This study focused on developing a new method to predict how different drugs work together against hard-to-treat bacteria, especially those that are emerging and not well-studied. Researchers created a system called TACTIC, which used data from nearly 3,000 drug interactions across 12 types of bacteria. They found effective drug combinations, including clarithromycin, ampicillin, and mecillinam, that work well against antibiotic-resistant bacteria, and they also suggested new treatments for bacterial eye infections. Who this helps: This benefits patients with antibiotic-resistant infections and eye conditions, as well as doctors treating these issues.

PubMed

Clinical Utility of Recently Food and Drug Administration-Approved IntelliSep Test (Sepsis Biomarker) for Early Diagnosis of Sepsis: Comparison with Other Biomarkers.

2024

Journal of clinical medicine

Sarani N, Dasgupta A, Enders M, Rowan L, Elsarraj H +6 more

Plain English
This study looked at a new blood test called IntelliSep, which helps diagnose sepsis—a severe infection response—by measuring how easily blood cells can change shape. Researchers tested this on 44 emergency room patients and found that the IntelliSep scores were about twice as high in patients with a high likelihood of sepsis compared to those with a low likelihood. This is important because it suggests that the IntelliSep test may provide more accurate early diagnosis of sepsis than older methods, potentially leading to faster treatment. Who this helps: This benefits emergency room doctors and patients at risk of sepsis.

PubMed

Identification of a Regenerative Protocol for Recellularizing Human Auricular Cartilage Scaffolds.

2024

Annals of plastic surgery

Ziegler ME, Alaniz L, Khan N, Lem M, Pham J +7 more

Plain English
This study looked at ways to regenerate ear cartilage using biological scaffolds made from human cartilage taken from donors. Researchers found that combining ear cartilage cells with fat-derived stem cells and platelet-rich plasma made the regrowth of cartilage much more effective, boosting collagen production by 56% and certain important compounds by 47%. This is important because it offers a new method for improving surgical reconstruction of the ear and other cartilage-based repairs. Who this helps: This helps patients needing ear reconstruction after injury, surgery, or congenital conditions.

PubMed

The Interplay Between Collisionless Magnetic Reconnection and Turbulence.

2024

Space science reviews

Stawarz JE, Muñoz PA, Bessho N, Bandyopadhyay R, Nakamura TKM +11 more

Plain English
This paper examines how two important processes in space plasma, magnetic reconnection and turbulence, interact with each other. Researchers reviewed new observations from NASA's spacecraft, focusing on three regions around Earth. They found that turbulence can create conditions that lead to magnetic reconnection, and vice versa, which can help us understand energy transfer in space environments. Who this helps: This benefits scientists studying space weather and its effects on satellites and technology on Earth.

PubMed

Mechanistic insight into multiple antibody binding to ADAMTS13 in immune thrombotic thrombocytopenic purpura.

2024

Research and practice in thrombosis and haemostasis

Halkidis K, Meng C, Pillai VG, Shay M, Liu S +1 more

Plain English
This study looked at how multiple antibodies interact with a protein called ADAMTS-13, which is important in a blood disorder called immune thrombotic thrombocytopenic purpura (iTTP). The researchers discovered that two specific antibodies could enhance ADAMTS-13 activity, but when both stimulating and inhibiting antibodies were present, the inhibitory effects were stronger, particularly when they modified a key area of a protein called von Willebrand factor (VWF). Understanding these interactions could lead to better tests and treatments for patients with iTTP. Who this helps: This research benefits patients with immune thrombotic thrombocytopenic purpura and their doctors.

PubMed

Ultra-high-throughput screening of antimicrobial combination therapies using a two-stage transparent machine learning model.

2024

bioRxiv : the preprint server for biology

Reuter MM, Lev KL, Albo J, Arora HS, Liu N +8 more

Plain English
Researchers developed a new system called M2D2 that uses machine learning to find effective combinations of existing antimicrobial drugs. They tested 946 combinations and discovered that a cerebrovascular drug works well with a common penicillin antibiotic to enhance effectiveness in fighting infections. This is important because it offers a faster and cheaper way to create new treatment options in the face of rising drug resistance. Who this helps: This helps doctors and patients looking for better treatment options for resistant infections.

PubMed

Structural and functional characterization of fosfomycin resistance conferred by FosB from Enterococcus faecium.

2022

Protein science : a publication of the Protein Society

Wiltsie V, Travis S, Shay MR, Simmons Z, Frantom P +1 more

Plain English
Researchers studied a specific enzyme called FosB found in the bacterium Enterococcus faecium, which is responsible for many serious infections in hospitals. They discovered that FosB does not work in the usual way of breaking down the antibiotic fosfomycin, as it uses a different chemical process than expected. This finding is important because it opens up the possibility of developing new treatments to fight infections caused by bacteria that are resistant to current antibiotics. Who this helps: This helps doctors and patients dealing with antibiotic-resistant infections.

PubMed

Relativistic Asymmetric Magnetic Reconnection.

2022

Physical review letters

Mbarek R, Haggerty C, Sironi L, Shay M, Caprioli D

Plain English
This study looked at how magnetic reconnection—an important process in space physics—works when conditions are not equal on both sides. Researchers found that the speed at which energy is released during this process depends on the type of plasma entering, showing that weaker magnetic energy leads to faster outflows. These findings are crucial for better understanding high-energy emissions from space phenomena, especially since many systems in space have uneven conditions. Who this helps: This helps scientists studying space physics and high-energy astrophysical phenomena.

PubMed

The Coaching for Cognition in Alzheimer's (COCOA) trial: Study design.

2022

Alzheimer's & dementia (New York, N. Y.)

Roach JC, Hara J, Fridman D, Lovejoy JC, Jade K +12 more

Plain English
The COCOA trial is researching how personalized lifestyle changes, like diet and exercise, alongside standard care, can slow cognitive decline in people with Alzheimer's disease and related dementias. The study compares two groups: one receiving standard treatment and general advice, and another getting tailored coaching based on their data. The goal is to see if these personalized interventions improve memory and daily function, especially in individuals early in their condition, which can help make dementia care more accessible and effective. Who this helps: This helps patients with Alzheimer's disease and their families.

PubMed

Faster Form of Electron Magnetic Reconnection with a Finite Length X-Line.

2021

Physical review letters

Pyakurel PS, Shay MA, Drake JF, Phan TD, Cassak PA +1 more

Plain English
This study looked at a specific type of magnetic reconnection involving electrons in space. Researchers found that a new, faster way for electrons to reconnect occurs when the magnetic structure is restricted in three dimensions, leading to a significantly higher reconnection rate—faster than in two dimensions. This finding is important because it improves our understanding of how magnetic fields behave in turbulent space environments, which can impact satellite operations and space weather predictions. Who this helps: This helps scientists and engineers working on satellite technology and space missions.

PubMed

Energy transfer in reconnection and turbulence.

2021

Physical review. E

Adhikari S, Parashar TN, Shay MA, Matthaeus WH, Pyakurel PS +3 more

Plain English
This study looked at how energy moves during two plasma processes: reconnection and turbulence. Researchers found that despite the different appearances of these processes, they transfer energy in similar ways. They also discovered that as reconnection happens faster, energy transfer changes in a related way. Understanding these energy transfers is important because it can help scientists better predict and control behaviors in plasma, which has implications for things like fusion energy and space weather. Who this helps: This helps researchers and engineers working on plasma technologies and space science.

PubMed

In vivo CRISPR base editing of PCSK9 durably lowers cholesterol in primates.

2021

Nature

Musunuru K, Chadwick AC, Mizoguchi T, Garcia SP, DeNizio JE +37 more

Plain English
Researchers used a gene-editing tool called CRISPR to permanently disable a gene in monkeys' livers that controls cholesterol production, delivering it through tiny fat particles injected into the bloodstream. After a single injection, the monkeys' cholesterol dropped by about 60% and stayed low for at least 8 months without any additional treatment. This proves that gene editing could offer heart disease patients a one-time treatment instead of taking cholesterol drugs for life.

PubMed

A first-in-human proof-of-concept trial of intravaginal artesunate to treat cervical intraepithelial neoplasia 2/3 (CIN2/3).

2020

Gynecologic oncology

Trimble CL, Levinson K, Maldonado L, Donovan MJ, Clark KT +6 more

Plain English
This study tested artesunate, a malaria drug, as a new treatment for cervical pre-cancer lesions known as CIN2/3. Out of 28 women who used the vaginal inserts, about 68% saw improvement in their condition, and 47% of those improved also cleared the HPV virus that caused the lesions. This is important because it offers a potentially effective and safer at-home treatment option for women with CIN2/3, which typically requires multiple medical appointments. Who this helps: This helps women diagnosed with cervical pre-cancer.

PubMed

Maternal psychological distress and child weight at 24 months: investigating indirect effects through breastfeeding in the All Our Families cohort.

2020

Canadian journal of public health = Revue canadienne de sante publique

Shay M, Tomfohr-Madsen L, Tough S

Plain English
This study looked at how maternal mental health issues during pregnancy affect child weight at 24 months, specifically through the impact of breastfeeding. Researchers found that mothers experiencing anxiety and depression breastfed for fewer weeks, which in turn was linked to a higher likelihood of their children being overweight. The analysis of 1,582 mother-child pairs indicates that addressing maternal mental health could improve breastfeeding duration and help reduce childhood obesity rates. Who this helps: This helps mothers and children, especially those struggling with mental health during pregnancy.

PubMed

Depressed mood and anxiety as risk factors for hypertensive disorders of pregnancy: a systematic review and meta-analysis.

2020

Psychological medicine

Shay M, MacKinnon AL, Metcalfe A, Giesbrecht G, Campbell T +3 more

Plain English
This study looked at how depression and anxiety during pregnancy relate to high blood pressure disorders known as hypertensive disorders of pregnancy (HDP). The researchers reviewed 44 studies involving over 61 million pregnancies and found that women with depression or anxiety were 39% more likely to develop HDP. This matters because understanding these mental health issues can help doctors identify and support at-risk pregnant women to prevent complications. Who this helps: This helps pregnant women struggling with depression and anxiety, as well as their healthcare providers.

PubMed

Energy Flux Densities near the Electron Dissipation Region in Asymmetric Magnetopause Reconnection.

2020

Physical review letters

Eastwood JP, Goldman MV, Phan TD, Stawarz JE, Cassak PA +12 more

Plain English
This study investigated how energy is released in a specific area near the Earth's magnetic field where magnetic reconnection occurs. The researchers discovered that there are strong energy flows from electrons, alongside the expected flows from ions, which had not been fully recognized before. These findings are important because they can change our understanding of how electrons move and gain energy in space, impacting future space weather models and technologies. Who this helps: This benefits scientists and engineers working on space weather prediction and management.

PubMed

Planning Telehealth for Older Adults With Atrial Fibrillation in Rural Communities: Understanding Stakeholder Perspectives.

2019

Clinical nursing research

Rush KL, Hatt L, Gorman N, Janicki L, Polasek P +1 more

Plain English
This study looked at how older adults with atrial fibrillation (AF) and healthcare providers in rural areas feel about using telehealth for cardiac care. It found that opinions varied widely: some patients and providers were open to telehealth while others had concerns based on their past experiences and the quality of local health services. Understanding these perspectives is crucial for creating effective telehealth programs that meet the needs of rural patients. Who this helps: This helps patients with atrial fibrillation in rural communities and their healthcare providers.

PubMed

Early outcomes of patient-specific posterior stabilized total knee arthroplasty implants.

2019

Journal of orthopaedics

Wheatley B, Nappo K, Fisch J, Rego L, Shay M +1 more

Plain English
This study looked at the results of total knee implants that are specifically made to fit individual patients, compared to standard implants. Researchers found that both types had similar outcomes, with one patient needing manipulation under anesthesia in the custom group and two in the standard group. Overall, there was no significant difference in recovery scores for either type, showing that patient-specific implants work as well as regular implants. Who this helps: Patients needing knee replacement surgery.

PubMed

Publisher Correction: Electron magnetic reconnection without ion coupling in Earth's turbulent magnetosheath.

2019

Nature

Phan TD, Eastwood JP, Shay MA, Drake JF, Sonnerup BUÖ +26 more

Plain English
This paper discusses corrections to previously published figures about how electrons behave in a specific area of Earth's magnetosphere called the magnetosheath. The corrections include changes to numeric scales and the direction of certain arrows in the figures, ensuring accurate representation of the data. This matters because precise data is crucial for understanding the interactions of particles in space, which can affect satellite operations and communication. Who this helps: This helps scientists studying space weather and its effects on technology.

PubMed

Characterization of the genomically encoded fosfomycin resistance enzyme from.

2019

MedChemComm

Travis S, Shay MR, Manabe S, Gilbert NC, Frantom PA +1 more

Plain English
This study focused on a specific enzyme called FosM, which helps certain bacteria resist a common antibiotic called fosfomycin. Researchers found that FosM is a unique type of enzyme that relies on manganese and does not favor specific chemicals found in some bacterial products. This is important because understanding how this resistance works can help develop better treatments for lung infections caused by these bacteria, particularly in patients with conditions like cystic fibrosis. Who this helps: This helps patients with cystic fibrosis and chronic lung diseases.

PubMed

Electron magnetic reconnection without ion coupling in Earth's turbulent magnetosheath.

2018

Nature

Phan TD, Eastwood JP, Shay MA, Drake JF, Sonnerup BUÖ +26 more

Plain English
This study looked at a process called magnetic reconnection in a turbulent region of space near Earth, specifically the magnetosheath, where particles can gain energy. Researchers found that there are electron jets moving in different directions without the expected ion jets accompanying them, which indicates a new way for energy to be transferred and dissipated in these turbulent conditions without ion involvement. This is significant because it changes our understanding of how energy conversion happens in small-scale turbulent plasmas, which is important for space weather and our overall understanding of magnetic processes in the universe. Who this helps: This helps scientists studying space weather and its effects on satellites and communications.

PubMed

On the Collisionless Asymmetric Magnetic Reconnection Rate.

2018

Geophysical research letters

Liu YH, Hesse M, Cassak PA, Shay MA, Wang S +1 more

Plain English
This study looked at how quickly magnetic fields can reconnect, which is important for understanding space and astrophysical phenomena. The researchers found that in both symmetric and asymmetric situations, the reconnection rate tends to be about 0.1, a consistent value that helps predict how magnetic fields behave in different environments. This matters because knowing this rate helps scientists better understand processes at places like the boundary of Earth's magnetic field. Who this helps: This benefits scientists and researchers studying space weather and magnetic fields.

PubMed

Electron-scale dynamics of the diffusion region during symmetric magnetic reconnection in space.

2018

Science (New York, N.Y.)

Torbert RB, Burch JL, Phan TD, Hesse M, Argall MR +44 more

Plain English
This research looked at how magnetic fields interact in space, particularly focusing on a specific event that happened on July 11, 2017, when spacecraft observed a reconnection site in Earth's magnetic field. They found that electrons were moving extremely fast, with some jets reaching speeds of 15,000 kilometers per second, and discovered unique patterns in their movement despite some turbulence in the area. Understanding these processes is important for grasping how energy is transferred in space, which can affect satellite operations and space weather. Who this helps: This benefits scientists and engineers working on space missions and understanding space weather impacts on technology.

PubMed

Kinetic Range Spectral Features of Cross Helicity Using the Magnetospheric Multiscale Spacecraft.

2018

Physical review letters

Parashar TN, Chasapis A, Bandyopadhyay R, Chhiber R, Matthaeus WH +11 more

Plain English
Researchers looked at how ion speed and magnetic field interactions change in space, focusing on data from the Magnetospheric Multiscale (MMS) spacecraft. They found that at larger scales, these interactions are well-aligned, but as they got to smaller scales, this alignment broke down due to changes in how protons behave. This is important because it helps scientists understand the complex dynamics of space plasma, which can affect satellite communications and space weather predictions. Who this helps: This benefits scientists and engineers working on space technology and satellite operations.

PubMed

Guide Field Reconnection: Exhaust Structure and Heating.

2018

Geophysical research letters

Eastwood JP, Mistry R, Phan TD, Schwartz SJ, Ergun RE +13 more

Plain English
This study looked at how a specific process in space, called guide field reconnection, affects the structure and temperature of particles in a part of the Earth's magnetic field called the magnetosheath. Researchers found that this process leads to two different temperature changes: while ions get hotter, electrons can actually cool down in certain areas. Understanding these changes is important because they help scientists better grasp how energy is transferred in space environments. Who this helps: This benefits scientists studying space weather and its effects on Earth.

PubMed

The Stressors and Coping Strategies of Older Adults With Persistent Atrial Fibrillation Prior to and Following Direct Current Cardioversion.

2017

Journal of applied gerontology : the official journal of the Southern Gerontological Society

Rush KL, Hatt L, Shay M, Gorman N, Laberge CG +2 more

Plain English
This study looked at the stressors faced by older adults who have persistent atrial fibrillation (AF) before and after a treatment called direct current cardioversion. Researchers interviewed 16 patients and found that before the procedure, they dealt with a mix of AF-related and other stressors, using various coping methods. After the procedure, while some non-AF stressors increased, patients felt less need to cope, even though they were encouraged to keep using their coping strategies to help manage stress and prevent AF from coming back. Who this helps: This helps older adults with atrial fibrillation and their caregivers.

PubMed

Seeing the rural healthcare journeys of older adults with atrial fibrillation through a photographic lens.

2017

Chronic illness

Rush KL, Oelke ND, Shay M, Pedersen C

Plain English
This study looked at how photographs can help explain the healthcare experiences of older adults living in rural areas with atrial fibrillation (AF), a heart condition. Researchers followed 10 participants over six months and found that photos added depth to their stories, illustrating different phases of their health journeys, including stable periods, times of uncertainty, and health crises. Key themes included how patients view their illness, their surroundings, and the support they receive, revealing important details about their experiences that words alone might miss. Who this helps: This benefits older patients with atrial fibrillation and their healthcare providers.

PubMed

Why does Steady-State Magnetic Reconnection have a Maximum Local Rate of Order 0.1?

2017

Physical review letters

Liu YH, Hesse M, Guo F, Daughton W, Li H +2 more

Plain English
This study looked at a phenomenon called magnetic reconnection, which is important in space physics and some types of plasma. Researchers found that the reconnection happens at a consistent speed of about 0.1, with a potential maximum of around 0.2, regardless of how energy is lost during the process. Understanding this speed helps scientists better grasp how magnetic fields behave in space, which is important for predicting solar flares and their effects on Earth. Who this helps: This helps scientists and researchers studying space weather and its impact on technology and life on Earth.

PubMed

Electron-scale measurements of magnetic reconnection in space.

2016

Science (New York, N.Y.)

Burch JL, Torbert RB, Phan TD, Chen LJ, Moore TE +47 more

Plain English
This study examined a process called magnetic reconnection, where magnetic energy is transformed into heat and kinetic energy of particles. Researchers used data from NASA's Magnetospheric Multiscale (MMS) mission, finding strong evidence for how electrons are accelerated and lose their magnetic connection at the edges of Earth's magnetic field. They observed that this process converts magnetic energy into energy for particles, showing specific measurements of the electric field and current involved. Who this helps: This information helps researchers and scientists studying space weather and the effects of magnetic fields on Earth.

PubMed

Magnetospheric Multiscale Satellites Observations of Parallel Electric Fields Associated with Magnetic Reconnection.

2016

Physical review letters

Ergun RE, Goodrich KA, Wilder FD, Holmes JC, Stawarz JE +26 more

Plain English
Researchers studied electric fields in the Earth's magnetosphere during a process called magnetic reconnection, specifically observing them with satellites. They discovered that certain electric field events were much stronger than expected, reaching up to 100 mV/m, and they are linked to complex, twisted magnetic fields. Understanding these electric fields helps clarify how magnetic reconnection happens, which can affect space weather and satellite operations. Who this helps: This helps scientists and engineers working on space missions and satellite technology.

PubMed

Magnetospheric Multiscale Observations of the Electron Diffusion Region of Large Guide Field Magnetic Reconnection.

2016

Physical review letters

Eriksson S, Wilder FD, Ergun RE, Schwartz SJ, Cassak PA +22 more

Plain English
Researchers used the Magnetospheric Multiscale (MMS) satellites to study a significant magnetic reconnection event in space. They found that two satellites measured a region where electrons were rapidly moving and heating up, while the other two detected the jets produced from this event. The guide field in this study was about four times stronger than expected, and they observed unexpected strong electric fields, highlighting a complex interaction of forces beyond what models predicted. Who this helps: This helps scientists understand space weather and its impact on satellite communications and technology.

PubMed

Ion-scale secondary flux ropes generated by magnetopause reconnection as resolved by MMS.

2016

Geophysical research letters

Eastwood JP, Phan TD, Cassak PA, Gershman DJ, Haggerty C +23 more

Plain English
This study looked at tiny structures called flux ropes that form at the Earth's magnetic boundary, specifically when magnetic fields reconnect. Researchers found that these flux ropes are about 7 times smaller than typical scales and contain a small amount of magnetic energy. The findings reveal a new type of flux rope occurring in a specific area of space, which helps us understand how solar winds interact with our planet's magnetic field. Who this helps: This research is valuable for scientists studying space weather and its effects on Earth.

PubMed

Observations of Hall Reconnection Physics Far Downstream of the X Line.

2016

Physical review letters

Mistry R, Eastwood JP, Haggerty CC, Shay MA, Phan TD +2 more

Plain English
In this study, scientists used the Wind spacecraft to examine the behavior of magnetic fields created during solar wind interactions. They found that unique magnetic fields, called Hall fields, can persist thousands of kilometers away from the initial point of interaction, known as the X line. This discovery helps us understand the lasting effects of these magnetic phenomena in space and their influence on solar wind behavior. Who this helps: This benefits researchers studying space weather and its effects on Earth.

PubMed

Intermittent Dissipation and Heating in 3D Kinetic Plasma Turbulence.

2015

Physical review letters

Wan M, Matthaeus WH, Roytershteyn V, Karimabadi H, Parashar T +2 more

Plain English
This study examined how turbulence behaves in plasma, which is a state of matter found in stars and space. Researchers found that the turbulence forms thin sheets of electric current that lead to heating and energy loss, with stronger currents causing more heating. Specifically, their simulations indicated that in high-energy environments, energy dissipation can vary greatly, meaning some areas get much hotter than others. Who this helps: This helps scientists studying space weather and astrophysics, as well as those developing technologies related to plasma.

PubMed

Energy partition in magnetic reconnection in Earth's magnetotail.

2013

Physical review letters

Eastwood JP, Phan TD, Drake JF, Shay MA, Borg AL +2 more

Plain English
This research looked at how energy is divided during a process called magnetic reconnection in a specific area of space around Earth called the magnetotail. The study found that the strongest form of energy comes from the movement of ions, while smaller amounts come from electrons and other energy types. Notably, in some areas, the energy carried by electromagnetic waves was also significant. Understanding this energy distribution helps us better grasp the dynamics in space that can impact satellite operations and space weather. Who this helps: This helps scientists and engineers working on space missions and satellite technology.

PubMed

Von Kármán energy decay and heating of protons and electrons in a kinetic turbulent plasma.

2013

Physical review letters

Wu P, Wan M, Matthaeus WH, Shay MA, Swisdak M

Plain English
This study looked at how energy decreases in a specific type of turbulent space plasma, using advanced computer simulations. The researchers found that at low levels of turbulence, electrons get heated more, while at high levels, protons become the main focus of heating. The results align with how we understand energy decay in similar systems, and they highlight that in natural settings like the solar wind, protons typically experience more heat due to stronger turbulence. Who this helps: This helps scientists studying space weather and astrophysical phenomena.

PubMed

New electric field in asymmetric magnetic reconnection.

2013

Physical review letters

Malakit K, Shay MA, Cassak PA, Ruffolo D

Plain English
This study looked at a new type of electric field that forms during a specific process called magnetic reconnection, which happens in space. Researchers found that this new "Larmor electric field" is different from another electric field previously known and may help scientists better understand where these reconnection events occur. This discovery is important because it could guide future space missions, like the Magnetospheric Multiscale mission, in finding these sites more effectively. Who this helps: This helps scientists and researchers studying space weather and its effects on Earth.

PubMed

Mutant p53R273H attenuates the expression of phase 2 detoxifying enzymes and promotes the survival of cells with high levels of reactive oxygen species.

2012

Journal of cell science

Kalo E, Kogan-Sakin I, Solomon H, Bar-Nathan E, Shay M +8 more

Plain English
This study looked at a specific mutation of the p53 gene, known as p53R273H, which is often found in cancer cells. Researchers found that this mutant form makes it harder for the cells to handle harmful molecules called reactive oxygen species (ROS), which can cause stress and damage. Specifically, they discovered that cells with this mutation produced lower levels of protective enzymes, leading to high ROS levels and allowing the cancer cells to survive better after stress. Who this helps: This research helps cancer patients by providing insights into how some tumors resist treatments and survive.

PubMed

Intermittent dissipation at kinetic scales in collisionless plasma turbulence.

2012

Physical review letters

Wan M, Matthaeus WH, Karimabadi H, Roytershteyn V, Shay M +4 more

Plain English
This research examined how turbulence behaves in a type of plasma that does not have collisions, focusing on the formation of current sheets. The study found that these current sheets, which can vary greatly in size and are particularly effective at dissipating energy, lead to uneven heating in the plasma. Specifically, stronger current structures are linked to higher rates of energy loss. Understanding this process is important because it reveals how energy behaves in space and astrophysical environments, which can affect space weather and other phenomena. Who this helps: This benefits scientists studying space and astrophysical plasmas.

PubMed

Super-Alfvénic propagation of substorm reconnection signatures and Poynting flux.

2011

Physical review letters

Shay MA, Drake JF, Eastwood JP, Phan TD

Plain English
This study looked at how energy is transferred during a specific type of magnetic reconnection in space, using computer simulations and data from satellites. Researchers discovered that a certain wave, moving much faster than sound waves encountered in space (around 1500-5500 kilometers per second), produces a strong energy transfer, which could generate visible auroras on Earth. This finding is important because it helps us understand the processes that lead to these beautiful light displays in the sky and how energy moves through space. Who this helps: This helps scientists studying space weather and its effects on Earth's atmosphere.

PubMed

Direct evidence for a three-dimensional magnetic flux rope flanked by two active magnetic reconnection X lines at Earth's magnetopause.

2011

Physical review letters

Øieroset M, Phan TD, Eastwood JP, Fujimoto M, Daughton W +6 more

Plain English
This study looked at a specific type of magnetic structure in space called a magnetic flux rope, which was observed by three spacecraft near Earth's magnetopause (the boundary between Earth's magnetosphere and space). The researchers found that this magnetic structure was surrounded by two active areas where magnetic energy was released, producing jets of plasma. They discovered unusual patterns of particles within the flux rope, with superthermal electrons (high-energy particles) detected at levels higher than what current theories would predict. Who this helps: This research benefits scientists and engineers working on space weather, as it improves our understanding of magnetic interactions that can affect satellite operations and communication systems.

PubMed

Clinical ladder program evolution: journey from novice to expert to enhancing outcomes.

2010

Journal of continuing education in nursing

Burket TL, Felmlee M, Greider PJ, Hippensteel DM, Rohrer EA +1 more

Plain English
This study looked at a program for nurses that helps them advance from novice to expert levels in their careers at a specific medical center. Over the past twenty years, the program has adapted to meet changes in the healthcare environment and has led to better patient care by encouraging nurses to mentor each other. The program recognizes and rewards outstanding nursing practice, which ultimately enhances patient outcomes. Who this helps: This benefits nurses seeking career advancement and patients receiving improved care.

PubMed

Asymmetry of the ion diffusion region Hall electric and magnetic fields during guide field reconnection: observations and comparison with simulations.

2010

Physical review letters

Eastwood JP, Shay MA, Phan TD, Øieroset M

Plain English
This study looked at how magnetic fields behave in a specific part of space called the Earth's magnetotail during a phenomenon known as magnetic reconnection. Researchers found that even a small guide field, which is about 20% of the main reconnecting field, significantly changes how ions move and affects the structure of the electric and magnetic fields, with results showing a clear mismatch in their distribution. Understanding these effects is crucial for accurately studying how magnetic reconnection occurs in natural settings, which has implications for space weather and satellite operations. Who this helps: This benefits scientists and engineers working on space weather and satellite technology.

PubMed

Publication data sourced from PubMed . Plain-English summaries generated by AI. Not medical advice.