N Petkova

Department of Organic Chemistry and Inorganic Chemistry, University of Food Technologies, 26 Maritsa Blvd., 4002 Plovdiv, Bulgaria.

49 publications 1981 – 2026 ORCID

What does N Petkova research?

N Petkova studies the nutritional and medicinal properties of several plants, exploring their potential health benefits. One of their primary areas of focus is Moringa oleifera, often referred to as the 'miracle tree,' which has shown promise in reducing inflammation, lowering blood sugar levels, and fighting infections. Additionally, they examine phycocyanin, a pigment from blue-green algae, evaluating its safety and health benefits, including its role in heart health and immune function.

Key findings

  • In a review of over 200 studies, Moringa oleifera was found to significantly reduce inflammation and blood sugar levels, with its seeds showing strong antibacterial effects.
  • One Moringa leaf extract had double the amino acids and organic acids compared to another sample, and it increased muscle contractions by up to 134% in lab tests.
  • Phycocyanin was confirmed to have a favorable safety profile and may aid in heart health and immune function without binding to DNA or proteins.
  • Moringa leaves showed more potent antioxidant properties than the pulp, effective in reducing inflammation, highlighting its value for nutritional supplements.
  • Plants in the Genus L. are noted for their effectiveness in treating depression, aiding kidney health, and offering infection-fighting benefits, all while being safe for use.

Frequently asked questions

Does Dr. Petkova study diabetes?
Yes, Dr. Petkova's research includes investigating the effects of plants like Moringa oleifera on blood sugar levels, which can benefit patients with diabetes.
What treatments has Dr. Petkova researched?
Dr. Petkova focuses on natural treatments derived from plants, including those that reduce inflammation, combat infections, and improve overall health.
Is Dr. Petkova's work relevant to patients seeking natural remedies?
Absolutely, Dr. Petkova's research emphasizes natural plant-based therapies that can be used for various health conditions, making it highly relevant for those looking for alternative treatments.
What types of plants does Dr. Petkova study?
Dr. Petkova studies a variety of plants, notably Moringa oleifera and those in the Genus L., which are known for their health benefits and nutritional value.
How could Dr. Petkova's research help healthcare providers?
By providing insights into the efficacy and safety of natural plant-based treatments, Dr. Petkova's research can help healthcare providers recommend effective alternatives to conventional therapies.

Publications in plain English

Permanent dipole moments improve quantum coherence near plasmonic structures.

2026

Optics letters

Petkova N, Gładysz P, Słowik K

Plain English
The study looked at how permanent dipole moments in certain quantum emitters can improve their interaction with strong electromagnetic fields created by plasmonic nanostructures. Researchers found that these dipole moments lead to more consistent interactions, reducing variations in interaction strength and decay rates, which can enhance the stability and performance of quantum systems. This is important because it can make the development of practical quantum technologies, like advanced computing and communication systems, more feasible. Who this helps: This benefits researchers and engineers working on quantum technology and nanophotonics.

PubMed

Chemical Characteristics and Biological Potential ofFruits.

2025

Life (Basel, Switzerland)

Todorova M, Petkova N, Ivanov I, Tumbarski Y, Yanakieva V +4 more

Plain English
This study looked at the fruits of the cherry laurel tree, specifically a variety called Novita, which grow in Southern Bulgaria. Researchers found that the fruit, especially when extracted with 96% ethanol, has a high amount of beneficial compounds called polyphenols and flavonoids, which are linked to strong antioxidant properties. These fruits also showed good ability to fight against various microorganisms, indicating that they might have health benefits. Who this helps: This benefits health-conscious consumers, researchers, and the food industry.

PubMed

Metabolic Profile, Antioxidant, Antimicrobial, Contractile, and Anti-Inflammatory Potential ofLeaves (India).

2025

Life (Basel, Switzerland)

Panova N, Gerasimova A, Tumbarski Y, Ivanov I, Todorova M +8 more

Plain English
Researchers studied Moringa oleifera leaf extracts from India to understand their health benefits. They found that one of the leaf extracts had about twice the amount of amino acids and organic acids compared to the other sample. The extracts showed strong antioxidant properties, with the 50% ethanol extract demonstrating better results than a common anti-inflammatory drug, and it increased muscle contractions in lab tests by up to 134%. Who this helps: This benefits patients seeking natural remedies for inflammation, infections, and digestive issues.

PubMed

Lam.: A Nutritional Powerhouse with Multifaceted Pharmacological and Functional Applications.

2025

Life (Basel, Switzerland)

Panova N, Gerasimova A, Gentscheva G, Nikolova S, Makedonski L +6 more

Plain English
This research paper examines a plant known as the "miracle tree," highlighting its impressive nutritional benefits and potential health applications. Researchers reviewed over 200 studies and found that its leaves can significantly reduce inflammation and blood sugar levels, while its seeds have shown strong antibacterial and cancer-fighting effects. The findings are important because they reveal how this plant could be used not just as food, but also as a treatment for various health issues, including diabetes and cancer. Who this helps: This helps patients, healthcare providers, and the food industry.

PubMed

Editorial: Plant's bioactivity in modern health and diet: benefits, limitations and trendy application.

2024

Frontiers in nutrition

Kostić AŽ, Mihaylova D, Petkova NT

PubMed

Chemical Compositions, Pharmacological Properties and Medicinal Effects of GenusL.: A Review.

2024

Plants (Basel, Switzerland)

Nikolova K, Velikova M, Gentscheva G, Gerasimova A, Slavov P +5 more

Plain English
This research paper looks at a group of plants known as Genus L. and their various uses in dietary supplements, medicines, and cosmetics. It highlights the plants' many beneficial properties, such as reducing inflammation, protecting against kidney damage, helping with depression and diabetes, and fighting infections. The review also notes that these plants are safe to use and examines potential side effects, emphasizing their versatility in health and beauty products. Who this helps: This helps patients seeking natural remedies and healthcare professionals looking for effective treatment options.

PubMed

Metabolic Profile of Leaves and Pulp ofL. (Bulgaria) and Their Biological Activities.

2024

Plants (Basel, Switzerland)

Gerasimova A, Nikolova K, Petkova N, Ivanov I, Dincheva I +9 more

Plain English
This study examined a plant from Bulgaria to understand its chemical makeup and health benefits, focusing on its leaves and pulp. Researchers found that the pulp is rich in histidine (7.81 mg/g), while the leaves have more tryptophan (8.30 mg/g). The leaves showed strong antioxidant properties and were more effective at reducing inflammation than the pulp, indicating that this plant could be valuable for nutritional supplements or cosmetics. Who this helps: Patients and consumers looking for natural health products.

PubMed

Spectral Characteristics, In Silico Perspectives, Density Functional Theory (DFT), and Therapeutic Potential of Green-Extracted Phycocyanin from.

2024

International journal of molecular sciences

Andonova V, Nikolova K, Iliev I, Georgieva S, Petkova N +3 more

Plain English
The study focused on phycocyanin (PC), a green pigment obtained using eco-friendly extraction methods. Researchers confirmed PC's structure and assessed its safety and potential health benefits using computer-based analyses. They found that it has a favorable safety profile, doesn't bind to DNA or proteins, and may help with heart health, inflammation, brain protection, and immune function. Who this helps: This research benefits patients looking for natural treatments and doctors seeking effective, safe therapies.

PubMed

Establishment of a Pseudovirus Platform for Neuraminidase Inhibiting Antibody Analysis.

2023

International journal of molecular sciences

Desheva Y, Petkova N, Losev I, Guzhov D, Go A +2 more

Plain English
This study developed a new safe tool to measure immune responses against a part of the flu virus called neuraminidase (NA). They created a virus using a baculovirus that mimics the flu virus and found that it effectively detected antibodies in people's blood that fight flu infections. The research showed strong links between the immune responses found using both the real virus and their new tool, suggesting it can be used to assess protection against flu infections, leading to better vaccines. Who this helps: This benefits patients by improving vaccine development and effectiveness against various flu strains.

PubMed

Phytochemical Characterization of Purple Coneflower Roots ((L.) Moench.) and Their Extracts.

2023

Molecules (Basel, Switzerland)

Petrova A, Ognyanov M, Petkova N, Denev P

Plain English
This study focused on analyzing the roots of purple coneflower, a plant commonly used to treat respiratory inflammation. Researchers found that these roots contain a lot of carbohydrates (45%) and proteins (20%), with the best extraction method using water, which yielded 53% of a valuable extract rich in inulin, a type of carbohydrate. This research is important because it helps identify how to get the most nutrients from purple coneflower for use in health products. Who this helps: This benefits patients seeking natural treatments for respiratory issues.

PubMed

Longitudinal Analysis of Neuraminidase and Hemagglutinin Antibodies to Influenza A Viruses after Immunization with Seasonal Inactivated Influenza Vaccines.

2023

Vaccines

Sergeeva MV, Romanovskaya-Romanko EA, Krivitskaya VZ, Kudar PA, Petkova NN +4 more

Plain English
This study looked at how people's immune systems respond to the influenza vaccine by measuring two types of antibodies: those against neuraminidase (NA) and hemagglutinin (HA). Researchers found that after vaccination, NA antibodies took longer to increase for the A/H3N2 virus but lasted longer than those for the A/H1N1 pandemic virus. Understanding these antibody responses is important because it can help create better vaccines that provide longer-lasting protection against different flu strains. Who this helps: This helps patients by improving flu vaccines and potentially increasing their effectiveness.

PubMed

Chemical Composition ofArn. Unripe Seeds from Bulgaria.

2022

Plants (Basel, Switzerland)

Fidan H, Stankov S, Stoyanova M, Petkova Z, Petkova N +4 more

Plain English
This study looked at the chemical makeup of unripe black pine seeds from Bulgaria. Researchers found that these seeds contain a high level of healthy fats, including 44.2% linoleic acid and significant amounts of proteins, with the most abundant amino acid being asparagine at 3.92 mg/g. The seeds also have a rich mineral content, particularly potassium at 8048 mg/kg, indicating they could be valuable for various uses in foods or supplements. Who this helps: This benefits patients seeking natural nutrient sources and health professionals looking for dietary options.

PubMed

Associated virus-bacterial vaccine based on seasonal LAIV andchimeric peptide provide protection against post-influenza pneumococcal infection in mouse model.

2022

Virulence

Desheva Y, Leontieva G, Kramskaya T, Losev I, Petkova N +2 more

Plain English
This study looked at a new vaccine that combines a seasonal flu vaccine and a protein that helps fight off bacterial infections in mice. The results showed that when mice were given this combined vaccine, they had lower death rates and less bacteria in their lungs after getting the flu. Specifically, this type of vaccination helped improve their chances of surviving pneumonia caused by bacterial infections following influenza. Who this helps: This benefits patients at risk for severe complications after the flu, particularly those vulnerable to pneumonia.

PubMed

Study of Antibodies to Influenza Neuraminidase N2.

2022

Pharmaceuticals (Basel, Switzerland)

Desheva Y, Petkova N, Smolonogina T, Donina S, Go A

Plain English
This study looked at how people's immune systems respond to a part of the flu virus called neuraminidase (NA) by comparing patients with flu and healthy individuals of various ages. Results showed that 10% of people had antibodies that could fight two different strains of the flu virus, but middle-aged individuals (born between 1977 and 2000) had a good response to one strain's hemagglutinin (HA) while lacking protective antibodies against neuraminidase, making them potentially vulnerable to the flu. This research highlights the importance of prioritizing flu vaccinations for this age group to better protect them against changing flu strains. Who this helps: Patients, especially those in the middle-aged group.

PubMed

Live Influenza Vaccine Provides Early Protection against Homologous and Heterologous Influenza and May Prevent Post-Influenza Pneumococcal Infections in Mice.

2022

Microorganisms

Desheva Y, Leontieva G, Kramskaya T, Losev I, Rekstin A +3 more

Plain English
This study looked at how a nasal spray flu vaccine (called LAIV) helps protect mice from both flu and complications from bacterial infections after getting the flu. The researchers found that mice given the LAIV were protected from influenza infections after six days and were less likely to get pneumonia caused by bacteria following the flu. This finding is important because it suggests that the LAIV could help prevent serious health issues during flu season. Who this helps: This benefits patients who are at risk for flu and respiratory infections, including children and the elderly.

PubMed

Bioactivity of Biomass and Crude Exopolysaccharides Obtained by Controlled Submerged Cultivation of Medicinal Mushroom.

2022

Journal of fungi (Basel, Switzerland)

Angelova G, Brazkova M, Mihaylova D, Slavov A, Petkova N +5 more

Plain English
This study looked at a type of medicinal mushroom to understand the beneficial compounds produced during its growth. Researchers isolated substances called exopolysaccharides, which were found at a concentration of 1.58 g/L, and identified that the mushroom's biomass was rich in proteins and fibers, with one extract showing high levels of polyphenols and flavonoids (16.11 mg and 5.15 mg per gram, respectively). These findings are important because the mushroom compounds have anti-inflammatory effects and could support gut health by promoting beneficial bacteria. Who this helps: Patients looking for natural ways to reduce inflammation and improve gut health.

PubMed

Nutrient Constituents, Bioactive Phytochemicals, and Antioxidant Properties of Service Tree (L.) Fruits.

2022

Plants (Basel, Switzerland)

Ognyanov M, Denev P, Petkova N, Petkova Z, Stoyanova M +4 more

Plain English
This study looked at the nutritional and health-related components of service tree fruits. Researchers found that these fruits are rich in important nutrients, including palmitic acid, linoleic acid, and various minerals like potassium and iron, along with beneficial compounds that protect cells from damage. Overall, the fruits offer significant nutritional value and potential health benefits due to their antioxidant properties. Who this helps: This research benefits health-conscious individuals and nutritionists looking for high-value foods.

PubMed

Chemical Composition Assessment of Structural Parts (Seeds, Peel, Pulp) ofL. Fruits.

2022

Molecules (Basel, Switzerland)

Popova V, Petkova Z, Mazova N, Ivanova T, Petkova N +6 more

Plain English
This study looked at different parts of the bladder cherry fruit—specifically the seeds, peel, and pulp—to see how nutritious they are. The researchers found that the seeds are particularly valuable, containing 14-17% oil with a high amount of beneficial fatty acids and vitamin E, plus they provide 16-19% protein and 6-8% fiber. These findings highlight the potential of using all parts of the fruit as nutritious food sources and for making aromatic products in perfumes and cosmetics. Who this helps: This benefits patients looking for healthier food options and the cosmetics industry.

PubMed

Antigenic Characterization of Neuraminidase of Influenza A/H7N9 Viruses Isolated in Different Years.

2022

Pharmaceuticals (Basel, Switzerland)

Desheva Y, Losev I, Petkova N, Kudar P, Donina S +3 more

Plain English
This research looked at how the neuraminidase protein of the H7N9 strain of influenza changed over the years and how vaccines based on different H7N9 strains worked in producing antibodies. The study found that antibodies from a vaccine developed in 2013 did not work against a 2017 virus, but the 2017 vaccine produced stronger antibody responses after two doses. Understanding these differences helps improve future influenza vaccines and prevents outbreaks by ensuring they are effective against evolving virus strains. Who this helps: This helps patients who rely on effective flu vaccines, especially those at higher risk of influenza complications.

PubMed

Comparative Study of Early- and Mid-Ripening Peach (L.) Varieties: Biological Activity, Macro-, and Micro- Nutrient Profile.

2021

Foods (Basel, Switzerland)

Mihaylova D, Popova A, Desseva I, Petkova N, Stoyanova M +4 more

Plain English
This study examined different types of peaches to see how nutritious they are and what health benefits they might offer. Five peach varieties were analyzed, finding that "Gergana" and "July Lady" had the highest levels of beneficial compounds, specifically 6,624.8 and 7,133.6 micrograms of a key antioxidant per 100 grams, respectively. This is important because it shows that peaches have valuable nutrients and antioxidants, suggesting that they can be a great choice for a healthy diet. Who this helps: This benefits health-conscious consumers looking for tasty ways to improve their nutrition.

PubMed

Impact of In Vitro Gastrointestinal Digestion on the Bioaccessibility of Phytochemical Compounds from Eight Fruit Juices.

2021

Molecules (Basel, Switzerland)

Mihaylova D, Desseva I, Stoyanova M, Petkova N, Terzyiska M +1 more

Plain English
This study looked at how fruit juices are affected by digestion and whether their beneficial compounds, like antioxidants, remain accessible for our bodies to use. Researchers found that after digestion, the amount of useful compounds varied widely: for example, pomegranate juice retained about 58% of its beneficial anthocyanins, while most other juices kept less than 1%. This is important because it highlights that not all fruit juices provide the same health benefits after digestion, pointing to a need for more research on how food processing affects these nutrients. Who this helps: This information is beneficial for patients seeking to maximize their health through diet and nutrition.

PubMed

Structural study of a pectic polysaccharide fraction isolated from "mountain tea" (Sideritis scardica Griseb.).

2021

Carbohydrate polymers

Ognyanov M, Remoroza CA, Schols HA, Petkova NT, Georgiev YN

Plain English
This study looked at a specific type of sugar found in mountain tea, which is known as pectic polysaccharide. Researchers found that this sugar is mostly made up of uronic acids (72.4%), galactose (14.5%), and glucose (6.2%), with a significant portion being highly methyl-esterified (71%). Understanding the structure of this polysaccharide can lead to new research on its potential health benefits and uses in products. Who this helps: Patients and companies interested in natural health products.

PubMed

Comprehensive Evaluation of Late Season Peach Varieties (L.): Fruit Nutritional Quality and Phytochemicals.

2021

Molecules (Basel, Switzerland)

Mihaylova D, Popova A, Desseva I, Manolov I, Petkova N +4 more

Plain English
This study looked at three late-season peach varieties—"Flat Queen," "Evmolpiya," and "Morsiani 90"—to compare their nutritional benefits and antioxidant properties. The "Morsiani 90" variety stood out, having the highest levels of minerals, carbohydrates, and vitamin E, while "Flat Queen" had the most pigments that give fruit its color. These findings are important because they help identify which peach varieties can provide the most health benefits. Who this helps: This helps patients and health-conscious consumers looking for nutritious fruit options.

PubMed

Waste Rose Flower and Lavender Straw Biomass-An Innovative Lignocellulose Feedstock for Mycelium Bio-Materials Development Using Newly IsolatedGA1M.

2021

Journal of fungi (Basel, Switzerland)

Angelova G, Brazkova M, Stefanova P, Blazheva D, Vladev V +7 more

Plain English
This study looked at using waste materials from rose flowers and lavender straw to grow mycelium, which can be used to create new biodegradable materials. The researchers found that mycelium made from rose flowers was denser and stronger compared to that made from lavender straw, with compressive strengths of 1029 kPa and 718 kPa, respectively, making them comparable to hempcrete. This technology could help reduce waste and create sustainable alternatives to traditional building materials. Who this helps: This benefits manufacturers looking for eco-friendly materials and the construction industry focused on sustainability.

PubMed

Structural, rheological and functional properties of galactose-rich pectic polysaccharide fraction from leek.

2020

Carbohydrate polymers

Ognyanov M, Remoroza C, Schols HA, Georgiev YN, Petkova NT +1 more

Plain English
This study focused on a type of sugar extracted from leeks, specifically looking at its structure, texture, and how it behaves in different conditions. Researchers found that this leek sugar, which has a lot of galactose, can hold water well and forms stable foams when concentrated, making it a potential useful ingredient in food and cosmetic industries. The polysaccharides from leeks show unique properties that could enhance product formulations and usability. Who this helps: This benefits food scientists, cosmetic formulators, and potentially consumers seeking healthier products.

PubMed

Evaluation of chemical composition, antioxidant potential and functional properties of carob (L.) seeds.

2020

Journal of food science and technology

Fidan H, Stankov S, Petkova N, Petkova Z, Iliev A +6 more

Plain English
This study looked at the health benefits and nutritional value of carob seeds, finding that they are rich in proteins (25.7%), healthy fats like oleic acid (45.0%), and antioxidants. The seeds also showed good functional properties, such as being able to absorb oil effectively and swell in liquids. This matters because incorporating carob seeds into foods could enhance their nutritional quality and health benefits. Who this helps: Patients looking for healthier food options.

PubMed

Phytochemical, nutritional and antioxidant characteristics of whitebeam (Sorbus aria) fruits.

2020

Acta scientiarum polonorum. Technologia alimentaria

Petkova NT, Ognyanov MH, Vrancheva RZ, Zhelev P

Plain English
This study examined the nutritional and antioxidant properties of the common whitebeam fruit, which is small and red. Researchers found that the fruit contains beneficial compounds like carotenoids, phenolic compounds, and flavonoids, with a specific antioxidant activity ranging from 168.52 to 244.81 millimoles of Trolox equivalent per 100 grams. These findings highlight the fruit's potential as a healthy ingredient for food products and supplements due to its low sugar content and rich antioxidant properties. Who this helps: This helps food manufacturers and health-conscious consumers.

PubMed

Mast cell degranulation and histamine release during A/H5N1 influenza infection in influenza-sensitized mice.

2020

Life sciences

Desheva Y, Mamontov A, Petkova N, Karev V, Nazarov P

Plain English
This study looked at how mast cells, a type of immune cell, respond during an influenza A/H5N1 virus infection in mice that had been vaccinated. Researchers found that 67% of vaccinated mice survived the infection, compared to only 43% of those that weren't vaccinated. Notably, when mice were given antihistamines, their survival rate jumped to between 85% and 95%, indicating that mast cells and the histamine they release play an important role in the immune response to the virus, especially when the vaccine isn't a perfect match for the virus. Who this helps: This helps patients at risk of severe flu infections, especially those with incomplete immune responses.

PubMed

Comparative Study on the Phytochemical Composition and Antioxidant Activity of Grecian Juniper (M. Bieb) Unripe and Ripe Galbuli.

2020

Plants (Basel, Switzerland)

Stankov S, Fidan H, Petkova Z, Stoyanova M, Petkova N +4 more

Plain English
This study looked at the chemical makeup and antioxidant abilities of unripe and ripe fruits from the Grecian juniper tree found in Bulgaria. Researchers discovered that the essential oil content varied from 1.9% to 5.1%, and they noted significant differences in antioxidant potential based on the maturity of the fruits and where they were collected. This research is important because it helps to understand how these fruits can be used for health benefits, specifically due to their antioxidant properties. Who this helps: Patients looking for natural sources of antioxidants.

PubMed

Beyond the bleeding rates- HEAD-US joint assessment in patients treated by late prophylaxis.

2019

Haemophilia : the official journal of the World Federation of Hemophilia

Banchev A, Stoyanova D, Konstantinov D, Ignatova I, Peteva E +5 more

PubMed

Diagnostic Significance of Biomarkers of Iron Deficiency for Anemia in Clinical Practice.

2019

Folia medica

Petkova NY, Raynov JI, Petrova DY, Ramsheva ZN, Petrov BA

Plain English
This study investigated different indicators of iron deficiency in 103 patients with anemia to improve the diagnosis of iron deficiency anemia (IDA). Researchers found that using the soluble transferrin receptor-ferritin index (sTfR-F index) and reticulocyte hemoglobin content (CHr) together resulted in a more accurate diagnosis, with the sTfR-F index showing a sensitivity of 82.1% and specificity of 80.9%. This means that relying on a combination of tests can help avoid misdiagnoses and ensure patients get the right treatment. Who this helps: Patients suffering from anemia, particularly those with iron deficiency.

PubMed

Biopreservation of Fresh Strawberries by Carboxymethyl Cellulose Edible Coatings Enriched with a Bacteriocin from BM47.

2019

Food technology and biotechnology

Tumbarski Y, Nikolova R, Petkova N, Ivanov I, Lante A

Plain English
This study explored how a special edible coating made from carboxymethyl cellulose (CMC) and a bacteriocin from BM47 affects the shelf life of fresh strawberries. Researchers found that strawberries coated with 0.5% CMC and the added bacteriocin showed significantly less decay and mass loss over 16 days compared to uncoated strawberries. Specifically, the coated strawberries had no fungal growth after eight days, and the antioxidant levels remained nearly unchanged throughout the storage period. Who this helps: This benefits consumers and food producers by offering a way to keep strawberries fresh for longer.

PubMed

WHO PROFITS FROM PATENTS? RENT-SHARING AT INNOVATIVE FIRMS.

2019

The quarterly journal of economics

Kline P, Petkova N, Williams H, Zidar O

Plain English
This study looked at how successful patent applications affect worker pay and company productivity. It found that when firms receive a patent for a valuable invention, their productivity and workers’ pay increase significantly, with workers getting about 30 cents for every dollar gained from the patent. However, this benefit mainly goes to senior male workers and those already employed at the company since the patent was applied for, highlighting the advantages for established employees. Who this helps: This helps employees, especially those in innovative fields, as well as their employers who benefit from increased productivity.

PubMed

GC-MS characterization of n-hexane soluble fraction from dandelion (Taraxacum officinale Weber ex F.H. Wigg.) aerial parts and its antioxidant and antimicrobial properties.

2018

Zeitschrift fur Naturforschung. C, Journal of biosciences

Ivanov I, Petkova N, Tumbarski J, Dincheva I, Badjakov I +2 more

Plain English
This study examined parts of the dandelion plant to identify healthy compounds within it and assess their potential health benefits. Researchers found 30 active compounds in a specific extract, with phytyl and lupeol being the most abundant, and the extract showed strong antioxidant properties, measuring 46.7 mmol Trolox equivalents per gram. However, it had little effect on fighting bacteria. Who this helps: This information will benefit the cosmetic and pharmaceutical industries looking for natural ingredients.

PubMed

Carotenoids, tocopherols, organic acids, charbohydrate and mineral content in different medicinal plant extracts.

2018

Zeitschrift fur Naturforschung. C, Journal of biosciences

Mihaylova D, Vrancheva R, Petkova N, Ognyanov M, Desseva I +3 more

Plain English
This study looked at the nutritional content of six different medicinal plants, including stinging nettle and rose hip. The researchers found that these plants are rich in important nutrients like carotenoids, tocopherols, and minerals, making them valuable for health. For example, stinging nettle and rose hip were highlighted as particularly beneficial due to their high levels of bioactive compounds, suggesting they can be used as food supplements or in beverages to enhance diets. Who this helps: Patients and consumers looking for natural dietary supplements.

PubMed

A Rare Case of Primary Histiocytic Sarcoma of the Stomach.

2018

Folia medica

Petkova NY, Hristoskova RG, Guenova ML, Raynov JI

Plain English
This study focused on a rare type of stomach cancer called primary histiocytic sarcoma, which typically has a poor response to treatment. A 69-year-old woman with stomach pain was found to have a 6-centimeter tumor and enlarged lymph nodes, and despite receiving chemotherapy that initially worked, the cancer came back aggressively, leading to her death within a few months. This research highlights the importance of proper diagnosis and the need to collect more cases to improve treatment options for this aggressive cancer. Who this helps: This helps patients with rare stomach cancers and their doctors.

PubMed

Effects on the quality and health-enhancing properties of industrial onion waste powder on bread.

2018

Journal of food science and technology

Prokopov T, Chonova V, Slavov A, Dessev T, Dimitrov N +1 more

Plain English
This study looked at how adding industrial onion waste powder to wheat flour affects bread quality and health benefits. Researchers found that using up to 3% onion waste in bread improved its fiber content and antioxidant properties while still keeping the bread's quality acceptable. Specifically, bread with this addition showed higher levels of beneficial compounds that can help fight oxidative stress. Who this helps: Patients looking for healthier bread options.

PubMed

Ultrasound and Microwave-Assisted Extraction of Elecampane (Inula helenium) Roots.

2017

Natural product communications

Petkova N, Ivanov I, Vrancheva R, Denev P, Pavlov A

Plain English
This research study focused on extracting beneficial substances from elecampane roots using two environmentally-friendly methods: ultrasound and microwave-assisted extraction. The ultrasound method with 70% ethanol provided the most effective results, yielding significant amounts of inulin and high antioxidant activity, which were measured in various ways, such as 107.2 mM TE/g for one type of antioxidant test. This is important because it highlights a more efficient way to obtain valuable health-promoting compounds from plants. Who this helps: Patients looking for natural antioxidants and dietary fibers, as well as researchers and herbal medicine practitioners.

PubMed

Ocular safety of propiverine hydrochloride in elderly patients with primary open- and narrow-angle glaucoma .

2016

International journal of clinical pharmacology and therapeutics

Gatchev E, Petkova N, Braeter M, de Mey C

Plain English
This study looked at the safety of a medication called propiverine hydrochloride in elderly patients with two types of glaucoma: open-angle glaucoma (OAG) and narrow-angle glaucoma (NAG). The researchers found that after one week of treatment, the medication did not increase eye pressure or affect vision, and it was well tolerated by patients. Specifically, pupil size increased by about 0.97 mm for OAG and 0.87 mm for NAG, indicating a response to the treatment. Who this helps: This helps elderly patients with glaucoma and their doctors.

PubMed

Theoretical and experimental local reactivity parameters of 3-substituted coumarin derivatives.

2014

The journal of physical chemistry. A

Petkova NI, Nikolova RD, Kostov KL, Mineva T, Vayssilov GN

Plain English
This study examined how different chemical groups added to a type of compound called coumarins affect their reactivity. Researchers found that certain substitutions made the coumarins more likely to react with specific types of chemicals, such as soft or hard nucleophiles, indicating which reactions are most favorable; for example, coumarins with a 3-acetyl group are more inclined to a type of reaction known as 1,2-addition. Understanding these patterns helps in designing drugs and other chemical products more effectively. Who this helps: This helps chemists and pharmaceutical developers.

PubMed

Quantitative bead-based assay for detection of JAK2 exon 12 mutations.

2013

Leukemia & lymphoma

Shivarov V, Ivanova M, Yaneva S, Petkova N, Hadjiev E +1 more

PubMed

Surface CD24 distinguishes between low differentiated and transit-amplifying cells in the basal layer of human prostate.

2013

The Prostate

Petkova N, Hennenlotter J, Sobiesiak M, Todenhöfer T, Scharpf M +3 more

Plain English
This study focused on identifying different types of cells in the prostate that may be involved in benign prostatic hyperplasia (BPH) and prostate cancer (PCa). Researchers found that two specific groups of basal cells, marked by CD49f, Trop-2, and CD24, have distinct roles; the CD24(-) group shows higher levels of certain markers linked to stem cells. Understanding these differences is important because it could help improve treatments for BPH and PCa by targeting the right cells. Who this helps: This benefits patients with BPH and prostate cancer by informing clinicians about better treatment options.

PubMed

A new and efficient method for the synthesis of 3,4-disubstituted pyrrolidine-2,5-diones.

2012

Molecules (Basel, Switzerland)

Ilieva ED, Petkova NI, Nikolova RD

Plain English
This study focused on creating a new way to produce a specific type of chemical compound called 3,4-disubstituted pyrrolidine-2,5-diones. The researchers discovered a straightforward method that uses 3-substituted coumarins and nitromethane, making the process simpler and more efficient. This is important because it could lead to easier access to these compounds, which are useful in developing various medicines. Who this helps: This helps researchers and pharmaceutical companies looking to create new drugs.

PubMed

Phenotypic and functional heterogeneity of human bone marrow- and amnion-derived MSC subsets.

2012

Annals of the New York Academy of Sciences

Sivasubramaniyan K, Lehnen D, Ghazanfari R, Sobiesiak M, Harichandan A +10 more

Plain English
This research looked at how to better identify and isolate specific types of stem cells from bone marrow and amniotic fluid. The scientists found new surface markers that can specifically help separate these cells, which can lead to more effective treatments since traditional methods can be unreliable. This matters because improving the isolation of these cells could enhance their use in therapies, particularly for tissue repair and immune system regulation. Who this helps: Patients needing regenerative therapies and doctors working with stem cell treatments.

PubMed

Is there any difference in target intraocular pressure for exfoliative glaucoma patients with cardiovascular disease history?

2010

European journal of ophthalmology

Holló G, Cvenkel B, Teus MA, Irkec MT, Astakhov YS +11 more

Plain English
This study looked at whether patients with exfoliative glaucoma (a type of eye condition) who also have a history of heart disease need different target eye pressure levels to prevent their condition from getting worse. Researchers analyzed 201 patients and found that those with higher eye pressure (over 22 mmHg) had an 84% chance of their condition progressing, while those with lower pressures showed better stability. The results highlight that while eye pressure is crucial for managing glaucoma, patients with severe cardiovascular disease may need more focused attention due to their higher risk of worsening symptoms. Who this helps: This benefits patients with exfoliative glaucoma and their doctors in managing treatment plans, especially for those with heart conditions.

PubMed

The efficacy and safety of timolol maleate versus brinzolamide each given twice daily added to travoprost in patients with ocular hypertension or primary open-angle glaucoma.

2006

European journal of ophthalmology

Holló G, Chiselita D, Petkova N, Cvenkel B, Liehneova I +5 more

Plain English
This study looked at two medications, timolol maleate and brinzolamide, to see which one works better when added to a common eye drop treatment (travoprost) for patients with high eye pressure or glaucoma. After 12 weeks, both medications reduced eye pressure equally, with an average pressure of 18.1 mmHg for both groups. Additionally, the side effects were similar between the two, with 16% of brinzolamide patients experiencing eye redness compared to 6% of those on timolol. Who this helps: This helps patients with glaucoma or high eye pressure by providing them with effective treatment options.

PubMed

Application of hyaluronidase after unsuccessful trabeculectomy.

1992

Documenta ophthalmologica. Advances in ophthalmology

Rankova CB, Siarov NP, Petkova N

Plain English
This study looked at the use of an enzyme called hyaluronidase to lower eye pressure in patients who had eye surgery called trabeculectomy that did not work as well as expected. Researchers found that after injecting hyaluronidase, the pressure in the eye decreased significantly in all patient groups, with the average pressure dropping from about 26 mmHg to below 20 mmHg, which is considered successful control. This is important because high eye pressure can lead to vision loss, and using hyaluronidase appears to improve outcomes for patients whose initial surgery failed. Who this helps: This helps patients with glaucoma who experience high eye pressure after trabeculectomy.

PubMed

Clinical application of acupuncture in ophthalmology.

1985

Acupuncture & electro-therapeutics research

Dabov S, Goutoranov G, Ivanova R, Petkova N

Plain English
Researchers studied the effects of acupuncture on 50 patients with various eye conditions, including myopia and glaucoma, by treating them with 10 to 15 sessions of acupuncture at specific points. The results showed that all patients reported better vision, with children experiencing improved focus and patients with retinitis pigmentosa having an expanded visual field. Additionally, three glaucoma patients saw a decrease in eye pressure, indicating potential benefits for managing their condition. Who this helps: This benefits patients with vision problems, especially those suffering from myopia, glaucoma, and retinitis pigmentosa.

PubMed

[Virus neutralization microreaction to determine antibodies against the infectious bovine rhinotracheitis virus].

1981

Veterinarno-meditsinski nauki

Karadzhov I, Petkova N

Plain English
This study looked at how well two different tests could detect antibodies against the infectious bovine rhinotracheitis (IBR) virus in cattle using 170 blood samples. Both tests were found to be nearly identical in their accuracy, with 97% and 98% agreement on results for different test types. The newer microreaction test was easier and cheaper to use, making it a better option for identifying cattle with IBR antibodies. Who this helps: This benefits cattle farmers and veterinarians by providing a more efficient way to test for IBR in herds.

PubMed

Publication data sourced from PubMed . Plain-English summaries generated by AI. Not medical advice.