Olga Rickards

Department of Biology, University of Rome Tor Vergata, Rome, Italy.

50 publications 2010 – 2026 ORCID

What does Olga Rickards research?

Dr. Rickards studies the historical aspects of celiac disease, particularly looking at how ancient diets may have affected health. She investigates ancient bones and DNA to explore how the disease has been present in human history and to understand its impact on health. Celiac disease is an autoimmune condition triggered by consuming gluten, a protein found in wheat, barley, and rye, which can lead to malnutrition and severe digestive issues. By studying bone chemistry and genetic markers from individuals who lived centuries ago, she connects their diets to modern conditions related to celiac disease.

Key findings

  • In her 2014 study, Rickards found significant bone chemistry differences in a young woman from ancient Italy, indicating a unique diet linked to chronic malnutrition and probable celiac disease.
  • Her research from 2012 identified the genetic marker HLA DQ 2.5 in a first-century AD woman, suggesting that celiac disease has existed for over 2,000 years.
  • Rickards’ work highlights the connection between diet and health over millennia, showing that historical dietary practices can inform our understanding of celiac disease today.

Frequently asked questions

Does Dr. Rickards study celiac disease?
Yes, she specifically studies the historical origins and implications of celiac disease through archaeological remains.
What treatments has Dr. Rickards researched?
While her work focuses on historical understanding, insights from her research can inform current dietary approaches for managing celiac disease.
Is Dr. Rickards' work relevant to patients with celiac disease?
Yes, her findings can help patients and healthcare providers understand the long-term impact of celiac disease and its dietary connections.
What methodologies does Dr. Rickards use in her research?
She uses stable isotope analysis to study bone remains and genetic analysis to identify markers associated with celiac disease.
How can Dr. Rickards' research help medical professionals?
Her work provides insights into the historical prevalence of celiac disease, which can enhance understanding and treatment approaches for patients today.

Publications in plain English

Marfan Before Marfan? Iconodiagnostic Analysis of a Possible Marfan Spectrum Phenotype in an Etruscan Sculpture.

2026

Clinical genetics

Pepe G, Rickards O, Colombai R

Plain English
Researchers looked at an ancient Etruscan statue to see if its unusual features might suggest signs of Marfan syndrome, a genetic condition that affects body tissues. They found that the statue shows traits like long limbs and chest deformities that match those seen in people with Marfan syndrome, indicating it could represent a person with this condition. This is important because it helps us understand how genetic disorders might have been present in history and how they can be identified through art. Who this helps: This helps historians, medical researchers, and potentially people with Marfan syndrome by providing insight into the past.

PubMed

Corrigendum to "Isotopic insights from carpological remains: One of the first datasets for the Italian Bronze age" [Data in brief 57 (2024) 111000].

2025

Data in brief

Cortese F, De Angelis F, Bontempo L, Carrara N, Cuda MT +6 more

Plain English
This paper corrects previous findings about plant remains from the Italian Bronze Age. It provides important data that helps understand the diets and agricultural practices of people during that time. The accurate information from this research is crucial for historians and archaeologists studying ancient cultures. Who this helps: This helps researchers studying ancient diets and agriculture.

PubMed

Isotopic insights from carpological remains: One of the first datasets for the Italian Bronze age.

2024

Data in brief

Cortese F, De Angelis F, Bontempo L, Carrara N, Cuda MT +6 more

Plain English
This study examined ancient seeds from four Italian sites dating back to the Bronze Age to understand how farming techniques were used during that time. Researchers analyzed 180 seeds, focusing on broad beans, wheat, emmer, and barley, using stable isotopes of carbon and nitrogen to identify practices like manuring and irrigation. They found that these techniques played a significant role in improving soil productivity, offering valuable insights into the agricultural practices of ancient Italian communities. Who this helps: This research benefits historians, archaeologists, and anyone interested in the development of early agriculture.

PubMed

Population genomics of post-glacial western Eurasia.

2024

Nature

Allentoft ME, Sikora M, Refoyo-Martínez A, Irving-Pease EK, Fischer A +159 more

Plain English
This study looked at the genetic information of 317 ancient people from northern and western Eurasia to understand how major human migrations after the Ice Age shaped these populations. The researchers found a clear genetic divide, showing that hunter-gatherers in the west were largely replaced by farming communities, while those in the east maintained their genetic identity for thousands of years. These migrations significantly affected the diversity of genes in these regions, leading to major changes in ancestry across Europe. Who this helps: This research helps historians and geneticists understand human migration patterns and their impact on modern populations.

PubMed

Publisher Correction: Population genomics of post-glacial western Eurasia.

2024

Nature

Allentoft ME, Sikora M, Refoyo-Martínez A, Irving-Pease EK, Fischer A +159 more

PubMed

La Sassa cave: Isotopic evidence for Copper Age and Bronze Age population dynamics in Central Italy.

2023

PloS one

Romboni M, Arienzo I, Di Vito MA, Lubritto C, Piochi M +6 more

Plain English
This study examines the diets and movement patterns of people buried in the La Sassa cave, Central Italy, during the Copper and Bronze Ages. Researchers found that dietary habits changed over time, particularly in one individual from a later period, indicating that people were trying new foods as cultures mixed. The study highlights increased cultural exchange and mobility among communities, as shown by changes in pottery styles and the variety of foods consumed. Who this helps: This benefits historians and archaeologists studying early human societies and their interactions.

PubMed

The evolutionary history of the polyQ tract in huntingtin sheds light on its functional pro-neural activities.

2022

Cell death and differentiation

Iennaco R, Formenti G, Trovesi C, Rossi RL, Zuccato C +14 more

Plain English
This study looked at a part of the huntingtin gene linked to Huntington's disease and found that variations in a sequence of CAG repeats (which encode for a protein fragment called polyQ) are important for brain cell functions. Researchers discovered that even small increases in the length of this polyQ tract can significantly influence the ability of brain cells to develop and function properly. This matters because understanding these changes helps explain how the huntingtin gene contributes to the evolution of more complex brain functions and the potential risks for diseases like Huntington's. Who this helps: This helps patients at risk for Huntington's disease and researchers studying neurodegenerative disorders.

PubMed

First Glimpse into the Genomic Characterization of People from the Imperial Roman Community of Casal Bertone (Rome, First-Third Centuries AD).

2022

Genes

De Angelis F, Romboni M, Veltre V, Catalano P, Martínez-Labarga C +2 more

Plain English
This study looked at the DNA of people buried in an ancient Roman community called Casal Bertone, who likely worked in a tannery. The researchers analyzed the genetic material of five individuals and found that three of them had ancestry from North Africa and the Near East, which were key areas for tannery work. They also discovered a variety of microbes linked to unhealthy working conditions in the tannery, indicating that these individuals lived and died near their workplace. Who this helps: This research benefits historians and archaeologists studying ancient communities and their working conditions.

PubMed

Bioarchaeological and palaeogenomic portrait of two Pompeians that died during the eruption of Vesuvius in 79 AD.

2022

Scientific reports

Scorrano G, Viva S, Pinotti T, Fabbri PF, Rickards O +1 more

Plain English
This study explored the remains of two people who died during the eruption of Mount Vesuvius in Pompeii in 79 AD. Researchers were able to analyze the DNA of one individual and found that their genetic makeup was closely related to other people in central Italy at that time, indicating a shared genetic background across the region. Additionally, they discovered evidence of spinal tuberculosis in the remains, highlighting health concerns in ancient populations. These findings enhance our understanding of the genetics and health of people in Pompeii during the Roman Empire. Who this helps: This research benefits historians, archaeologists, and public health experts studying ancient populations.

PubMed

Genomic ancestry, diet and microbiomes of Upper Palaeolithic hunter-gatherers from San Teodoro cave.

2022

Communications biology

Scorrano G, Nielsen SH, Vetro DL, Sawafuji R, Mackie M +12 more

Plain English
Researchers studied the ancient DNA and dental remains of two hunter-gatherers from a cave in Italy to learn about their diet and genetics. They found that these individuals shared a unique genetic background not previously documented in Italy, indicating they survived the last Ice Age in a specific area and later contributed to population growth across Europe. Their diet mainly consisted of animal proteins, which influenced the bacteria found in their mouths. Who this helps: This helps historians and anthropologists understand early human life and migration patterns.

PubMed

How Does Diet Influence Our Lives? Evaluating the Relationship between Isotopic Signatures and Mortality Patterns in Italian Roman Imperial and Medieval Periods.

2021

Molecules (Basel, Switzerland)

Baldoni M, Nardi A, De Angelis F, Rickards O, Martínez-Labarga C

Plain English
This study looked at how people’s diets affected their survival rates during the Roman and Medieval periods in Italy. Researchers analyzed data from 616 people across 18 archaeological sites and found that nitrogen in their diets had a significant impact on mortality rates. Specifically, during the Roman period, different diets influenced men and women, while in the Medieval period, higher levels of carbon in the diet correlated with increased death risk. Who this helps: This helps historians and researchers understand how diet impacted health in ancient societies.

PubMed

Uniparental Lineages from the Oldest Indigenous Population of Ecuador: The Tsachilas.

2021

Genes

Di Corcia T, Scano G, Martínez-Labarga C, Sarno S, De Fanti S +2 more

Plain English
This study looked at the Tsachilas, one of Ecuador's oldest indigenous groups, by analyzing their genetic makeup to learn more about their history and connections to other populations. Researchers examined the DNA of 70 Tsachilas mothers and 26 Tsachilas fathers and found that they share genetic similarities with other nearby groups, suggesting a shared ancestry and a link to the Incas. Understanding these connections is important for preserving the history and identity of indigenous populations. Who this helps: This research benefits indigenous communities and historians who aim to preserve and understand their cultural heritage.

PubMed

Ancient genomes from a rural site in Imperial Rome (1-3cent. CE): a genetic junction in the Roman Empire.

2021

Annals of human biology

De Angelis F, Veltre V, Romboni M, Di Corcia T, Scano G +3 more

Plain English
This study looked at the ancient DNA of 25 individuals buried in a burial site in Imperial Rome to understand the genetic makeup of its population. Researchers found that the DNA of 7 of these individuals shows similarities with today’s Southern Mediterranean and Southern Near Eastern populations, indicating a mix of ancestral backgrounds. This helps us understand how diverse the population of Rome was and sheds light on the influences from surrounding regions. Who this helps: This research benefits historians and archaeologists by providing insights into the demographics of ancient Roman society.

PubMed

Reconstruction of the human peopling of Europe: a genetic insight.

2021

Annals of human biology

Caramelli D, Posth C, Rickards O

PubMed

Exploring mobility in Italian Neolithic and Copper Age communities.

2021

Scientific reports

De Angelis F, Pellegrini M, Martínez-Labarga C, Anzivino L, Scorrano G +19 more

Plain English
This study looked at how people moved around in central and southern Italy during the late Neolithic and Copper Age by examining the chemical composition of teeth from 126 individuals. The findings showed that most people lived a more settled lifestyle, with little evidence of extensive mobility; in fact, only a few individuals were identified as having moved around significantly. This matters because it helps us understand the social structure and lifestyle of ancient communities in Italy, showing a clear difference from later Bronze Age populations. Who this helps: This helps researchers and historians understanding ancient human behaviors and societal development.

PubMed

Concerted variation of the 3' regulatory region of Ig heavy chain and Gm haplotypes across human continental populations.

2020

American journal of physical anthropology

Frezza D, Martinez-Labarga C, Giambra V, Serone E, Scano G +3 more

Plain English
This research studied genetic variations in a specific part of the immune system related to immunoglobulin genes across different human populations. They analyzed data from 3,100 individuals from 26 populations and found that certain genetic patterns are linked to how well these immune genes function. Understanding these patterns is important because they can reveal how our immune systems have evolved in different parts of the world, which could influence health responses in those populations. Who this helps: This helps researchers and doctors working on immune-related diseases.

PubMed

A multidisciplinary approach for investigating dietary and medicinal habits of the Medieval population of Santa Severa (7th-15th centuries, Rome, Italy).

2020

PloS one

Gismondi A, Baldoni M, Gnes M, Scorrano G, D'Agostino A +11 more

Plain English
Researchers studied the eating and medicinal habits of people who lived in the Santa Severa area of Rome between the 7th and 15th centuries. They analyzed 120 sets of human remains and 94 samples of dental plaque, discovering that these individuals had a varied diet including meat from cattle, sheep, pigs, and chickens, as well as cereal grains, dairy products, and even some marine foods. Additionally, they found evidence suggesting the use of medicinal plants, including those that may have treated malaria, indicating a rich understanding of health practices during that time. Who this helps: This research benefits historians, archaeologists, and anyone interested in the dietary and health practices of medieval populations.

PubMed

Leopoli-Cencelle (9th-15th centuries CE), a centre of Papal foundation: bioarchaeological analysis of the skeletal remains of its inhabitants.

2020

Annals of human biology

Baldoni M, Stasolla FR, Scano G, Marsella LT, Rickards O +1 more

Plain English
This study analyzed the skeletal remains of 877 people from the medieval city of Leopoli-Cencelle, focusing on their health, lifestyles, and mortality patterns. Researchers found that many infants and young children died early, and women had shorter lifespans compared to men, which was common before antibiotics. Overall, the inhabitants seemed relatively healthy, except for a few individuals with specific health issues. Understanding their lives helps paint a clearer picture of life in the Italian Middle Ages. Who this helps: This benefits historians and archaeologists studying medieval Italian society.

PubMed

"COVID-19 and the epistemology of epidemiological models at the dawn of AI": comment from the editors.

2020

Annals of human biology

Zemel BS, Cameron N, Rickards O

PubMed

Dissecting the Pre-Columbian Genomic Ancestry of Native Americans along the Andes-Amazonia Divide.

2019

Molecular biology and evolution

Gnecchi-Ruscone GA, Sarno S, De Fanti S, Gianvincenzo L, Giuliani C +16 more

Plain English
This study looked at the genetic backgrounds of Native American groups along the Andes and Amazon regions to better understand their ancestry before European contact. Researchers analyzed the DNA of 229 individuals from various Central and South American ethnic groups, finding that most had specific Native American genetic traits with minimal European or African influence. They discovered that all non-Andean South Americans likely share a common ancestral lineage, while relationships between Andean and Mesoamerican populations are not as closely linked as previously believed. Who this helps: This research benefits anthropologists and historians studying Native American ancestry and migration patterns.

PubMed

First analysis of ancient burned human skeletal remains probed by neutron and optical vibrational spectroscopy.

2019

Science advances

Festa G, Andreani C, Baldoni M, Cipollari V, Martínez-Labarga C +12 more

Plain English
This study looked at ancient bones that were burned, which can change their structure and make it harder for researchers to analyze them. By using advanced techniques like neutron and optical spectrometry, the researchers were able to create a detailed profile of these burned bones and understand how different heating conditions affected them. This finding is important because it helps archaeologists and anthropologists learn more about the burial and cooking practices of past cultures. Who this helps: Archaeologists and anthropologists studying ancient practices.

PubMed

Mitochondrial variability in the Mediterranean area: a complex stage for human migrations.

2018

Annals of human biology

De Angelis F, Scorrano G, Martínez-Labarga C, Scano G, Macciardi F +1 more

Plain English
This study looked at the genetic differences in the mitochondria, which are parts of cells that give energy, in people from the Mediterranean area to understand how human migrations have shaped these populations over time. It was found that the genetic material from Neolithic people, who lived around 10,000 years ago, is more common than that of earlier hunter-gatherers, highlighting the significant impact of the Neolithic revolution and later migrations. Understanding these migrations is important because it helps us piece together the complex history that has influenced the genetic diversity seen in Mediterranean populations today. Who this helps: This helps researchers and historians studying human migration and population genetics.

PubMed

Human population genetics of the Mediterranean.

2018

Annals of human biology

Comas D, Luiselli D, Rickards O

PubMed

Signs of continental ancestry in urban populations of Peru through autosomal STR loci and mitochondrial DNA typing.

2018

PloS one

Messina F, Di Corcia T, Ragazzo M, Sanchez Mellado C, Contini I +4 more

Plain English
This study examined the genetics of people living in urban Peru, focusing on how their ancestral backgrounds reflect a mix of Native American, African, and European heritage. Researchers analyzed DNA samples from 296 individuals and found that 67% of urban Peruvians showed strong similarities to Native Amazon populations, with only about 1% linked to European ancestry and 22% to African ancestry. Understanding this genetic diversity is important because it sheds light on the effects of historical migrations and helps improve studies in genetics and forensics in Peru. Who this helps: This benefits researchers, doctors, and public health officials working with diverse populations in Peru.

PubMed

Who were the miners of Allumiere? A multidisciplinary approach to reconstruct the osteobiography of an Italian worker community.

2018

PloS one

Baldoni M, Scorrano G, Gismondi A, D'Agostino A, Alexander M +5 more

Plain English
This research studied the bones of 70 people from a mining community in Allumiere, Italy, dating back to the 15th and 16th centuries. The findings revealed that there were more men than women in the community and that the workers showed signs of physical stress related to their mining jobs. Their diet was mostly omnivorous, heavily featuring plants and animals like sheep and cattle, and they also used medicinal plants, indicating they had knowledge of herbal medicine. Who this helps: This information helps historians and archaeologists understand the lives and diets of early mining communities.

PubMed

Mitochondrial characterisation of two Spanish populations from the Vera and Bejar valleys (Central Spain).

2018

Annals of human biology

Varano S, Gaspari L, De Angelis F, Scano G, Contini I +2 more

Plain English
This study examined the mitochondrial DNA of 137 people from two nearby Spanish regions, Vera and Bejar, to see if the Sierra de Gredos mountains affected their genetic differences. The researchers found that while both populations had similar mitochondrial lineages associated with Europe and some groups linked to Africa, there was no significant genetic difference between them. This finding shows that the mountains do not act as a barrier to genetic exchange between these communities. Who this helps: This helps researchers and scientists understand human genetic diversity in local populations.

PubMed

Linking between genetic structure and geographical distance: Study of the maternal gene pool in the Ethiopian population.

2017

Annals of human biology

Messina F, Scano G, Contini I, Martínez-Labarga C, De Stefano GF +1 more

Plain English
This study looked at the genetic makeup of two groups in Ethiopia—the Amhara and Oromo populations—to see how their genetics related to their geographical locations. Researchers examined 173 individuals and found that their mitochondrial DNA (genetic material passed from mothers) showed a link between genetic differences and distances on the map, supporting the idea that people who live closer together tend to have more similar genetics. This matters because it helps us understand how populations have moved and mixed over time in Africa, Europe, and the Middle East. Who this helps: This helps researchers studying human genetics and population history.

PubMed

Bight of Benin: a Maternal Perspective of Four Beninese Populations and their Genetic Implications on the American Populations of African Ancestry.

2017

Annals of human genetics

Primativo G, Ottoni C, Biondi G, Serafino S, Martínez-Labarga C +4 more

Plain English
This study examined the genetic history of four groups of people from Benin, Africa, by analyzing samples from 193 individuals. Researchers found that these populations are closely related to neighboring groups and have a significant connection to African ancestry in some American populations. This is important because it highlights Benin's role in history, especially regarding the slave trade, and how those ancestral ties continue to affect people today. Who this helps: This benefits researchers studying genetic diversity and the history of African descendants in America.

PubMed

East of the Andes: The genetic profile of the Peruvian Amazon populations.

2017

American journal of physical anthropology

Di Corcia T, Sanchez Mellado C, Davila Francia TJ, Ferri G, Sarno S +2 more

Plain English
This study looked at the genetic makeup of four communities in the Peruvian Amazon (Ashaninka, Huambisa, Cashibo, and Shipibo) to see how their genes differ from each other and from people living in the Andes mountains. The researchers found a lot of genetic diversity in these Amazon communities, especially in the Ashaninka, Huambisa, and Shipibo, while the Cashibo showed little mixing with their neighbors. Understanding these genetic links is important because it reveals how history and geography shaped the populations in these two environments and shows that there was some interaction between Amazonian and Andean peoples long before modern times. Who this helps: This helps researchers studying human genetics and the history of populations.

PubMed

Variability and distribution of COL1A2 (type I collagen) polymorphisms in the central-eastern Mediterranean Basin.

2016

Annals of human biology

Scorrano G, Lelli R, Martínez-Labarga C, Scano G, Contini I +3 more

Plain English
This study looked at the genetic differences in the COL1A2 gene, which is important for producing type I collagen, in people from the central-eastern Mediterranean area. Researchers examined blood and saliva samples from 308 individuals and found that Europeans had similar genetic patterns, while there were noticeable differences in Egyptians and Turks. This information is important because it helps us understand how geography and population movement have shaped genetic diversity in this region. Who this helps: This helps researchers and medical professionals studying genetic diseases related to collagen.

PubMed

Prof. Gian Franco De Stefano (Turin, September 3rd 1939 - Rome, January 1st 2016).

2016

Annals of human biology

De Angelis F, Rickards O

PubMed

Exploring the mitochondrial DNA variability of the Amazonian Yanomami.

2016

American journal of human biology : the official journal of the Human Biology Council

Varano S, Scorrano G, Martínez-Labarga C, Finocchio A, Rapone C +2 more

Plain English
This study looked at the genetic makeup of the Yanomami people in Brazil by analyzing hair samples collected in 1958. Researchers found that 98% of the mitochondrial DNA was Native American, while 2% was African, indicating a high level of genetic diversity among the Santa Isabel Yanomami compared to other groups. This genetic diversity may be linked to interactions with non-Yanomami populations and the influence of gold mining, suggesting that their location reduced their isolation and allowed for greater mixing with other genetic groups. Who this helps: This research benefits geneticists, anthropologists, and those studying Indigenous populations.

PubMed

Prof. Gian Franco De Stefano (Turin, September 3rd 1939-Rome, January 1st 2016).

2016

Collegium antropologicum

De Angelis F, Rickards O

PubMed

Methodological strategies to assess the degree of bone preservation for ancient DNA studies.

2015

Annals of human biology

Scorrano G, Valentini F, Martínez-Labarga C, Rolfo MF, Fiammenghi A +7 more

Plain English
This study focused on how to determine if ancient bones are likely to contain DNA by examining their preservation. Researchers found that better preservation of the bone's inorganic parts was linked to a higher chance of finding DNA, which can help scientists choose the best samples for DNA testing. This is important because it saves time and resources in ancient DNA research by allowing researchers to focus on the most promising samples. Who this helps: This benefits researchers working with ancient DNA and archaeologists.

PubMed

Traces of forgotten historical events in mountain communities in Central Italy: A genetic insight.

2015

American journal of human biology : the official journal of the Human Biology Council

Messina F, Finocchio A, Rolfo MF, De Angelis F, Rapone C +5 more

Plain English
This study looked at the genetic history of people living in seven isolated mountain villages in Central Italy to understand how their population has changed over time. Researchers analyzed DNA from 346 individuals and found that while most genetic markers were typical of Western Europe, some markers pointed to connections with populations from the Near East, suggesting some mixing might have occurred. Importantly, they discovered a unique paternal lineage that indicates a historical settlement from Anatolia, reinforcing the idea that these mountain communities have a distinct and varied genetic background. Who this helps: This research benefits historians and geneticists studying human migration and the influences of different cultures on isolated communities.

PubMed

The Paternal Landscape along the Bight of Benin - Testing Regional Representativeness of West-African Population Samples Using Y-Chromosomal Markers.

2015

PloS one

Larmuseau MH, Vessi A, Jobling MA, Van Geystelen A, Primativo G +5 more

Plain English
This study examined the genetic diversity of Y-chromosomes in four populations along the Bight of Benin in West Africa, which is important for understanding regional genetic representation. The researchers found that geographic proximity is the best indicator of genetic similarity, but some samples from local populations do not accurately represent their region. This research is crucial because it helps improve the accuracy of genetic studies and applications that rely on representative samples, particularly in areas like West Africa that have been under-studied. Who this helps: This benefits researchers and geneticists working on population studies and forensics.

PubMed

Linguistic, geographic and genetic isolation: a collaborative study of Italian populations.

2014

Journal of anthropological sciences = Rivista di antropologia : JASS

Capocasa M, Anagnostou P, Bachis V, Battaggia C, Bertoncini S +29 more

Plain English
This study explored the genetic diversity of human populations in Italy, focusing on different ethnic and linguistic groups to understand how their unique histories have shaped their genetics. Researchers found that the genetic differences among these populations were significant, with Italy showing greater diversity than many other parts of Europe, especially within distances up to 800 kilometers. This is important because it highlights how cultural and social factors, like language, influence genetic differences, which can have implications for health and anthropology. Who this helps: This helps patients and researchers studying genetic health and diversity in specific populations.

PubMed

Notice of concern.

2014

Annals of human biology

Cameron N, Rickards O, Zemel B

PubMed

A global analysis of Y-chromosomal haplotype diversity for 23 STR loci.

2014

Forensic science international. Genetics

Purps J, Siegert S, Willuweit S, Nagy M, Alves C +158 more

Plain English
This study looked at Y-chromosomes from almost 20,000 men across 129 populations in 51 countries to understand genetic diversity in specific DNA markers. Researchers found that a set of 23 markers provided better distinctions in genetic profiles than other marker sets but showed similar population patterns. The findings highlight the importance of choosing the right DNA markers for forensic work, helping to accurately identify individuals in investigations. Who this helps: This helps forensic scientists and law enforcement.

PubMed

Palaeodiet reconstruction in a woman with probable celiac disease: a stable isotope analysis of bone remains from the archaeological site of Cosa (Italy).

2014

American journal of physical anthropology

Scorrano G, Brilli M, Martínez-Labarga C, Giustini F, Pacciani E +5 more

Plain English
Researchers examined the bones of a young woman from ancient Italy to learn about her diet and how it might connect to celiac disease. They found that her bone chemistry showed significant differences, indicating she had a unique diet that likely contributed to chronic malnutrition linked to celiac disease. This study highlights how analyzing ancient bones can provide insight into health issues related to diet and may help us understand the historical impact of celiac disease. Who this helps: This helps patients with celiac disease and healthcare providers.

PubMed

[Ancient DNA: principles and methodologies].

2013

Medicina nei secoli

De Angelis F, Scorrano G, Rickards O

Plain English
This paper looks at how scientists study ancient DNA to learn about the traits of early human populations. It reviews the latest techniques and principles used in this field, showing that modern methods are improving our understanding of our ancient ancestors. This research is important because it helps us piece together the history of human evolution and migration. Who this helps: This helps researchers, historians, and anyone interested in human ancestry.

PubMed

16(th) IHIW: population global distribution of killer immunoglobulin-like receptor (KIR) and ligands.

2013

International journal of immunogenetics

Hollenbach JA, Augusto DG, Alaez C, Bubnova L, Fae I +14 more

Plain English
This study looked at the distribution of a specific group of genes called KIR across 105 different populations around the world. Researchers gathered information from over 120 reports and found distinct patterns in how these genes vary by region. Understanding these patterns is important because it can help improve treatments and therapies related to the immune system. Who this helps: This benefits researchers and doctors working in immunology and genetics.

PubMed

Surname and Y chromosome in Southern Europe: a case study with Colom/Colombo.

2012

European journal of human genetics : EJHG

Martínez-González LJ, Martínez-Espín E, Álvarez JC, Albardaner F, Rickards O +3 more

Plain English
This study explored the possible origins of Christopher Columbus by analyzing the Y chromosomes of men with the surnames Colom and Colombo from Southern Europe. Researchers looked at 238 men from Spain and 114 men from Italy and found that the Italian Colombo group was genetically diverse, while the Spanish Colom group had less genetic variation, suggesting a closer connection among them. This matters because it supports the theory that Columbus may have been Catalan rather than Italian, providing insight into the historical and cultural identity of this famous figure. Who this helps: This helps historians and linguists understand the historical roots of notable figures and their potential cultural backgrounds.

PubMed

Identification of ancient Olea europaea L. and Cornus mas L. seeds by DNA barcoding.

2012

Comptes rendus biologies

Gismondi A, Rolfo MF, Leonardi D, Rickards O, Canini A

Plain English
This study looked at ancient seeds found in Italy to learn more about how people lived during the Neolithic period. By using modern DNA techniques, researchers successfully identified these seeds as coming from olive trees (Olea europaea) and dogwoods (Cornus mas). This is important because it helps us understand what plants were used for food and trade, giving us insight into the diets and customs of early Italian communities. Who this helps: This helps researchers and historians studying ancient agriculture and diets.

PubMed

Examining dietary variability of the earliest farmers of south-eastern Italy.

2012

American journal of physical anthropology

Lelli R, Allen R, Biondi G, Calattini M, Barbaro CC +8 more

Plain English
This study looked at the changing diets of the first farmers in south-eastern Italy by analyzing the chemical makeup of their bones. Researchers found that people living near the coast had diets richer in marine foods, while there was a lot of variation in diets across the region, showing that these early farmers ate a diverse range of foods, unlike early farmers in other parts of Europe. This is important because it provides new insights into how farming affected diets in different areas and can help us understand the development of agriculture in the Mediterranean. Who this helps: This helps scientists and historians studying early human diets and agriculture.

PubMed

Origin of celiac disease: how old are predisposing haplotypes?

2012

World journal of gastroenterology

Gasbarrini G, Rickards O, Martínez-Labarga C, Pacciani E, Chilleri F +4 more

Plain English
This study looked at the remains of a young woman from the first century AD who showed signs of malnutrition, which might indicate celiac disease. Researchers analyzed her DNA and found she had a specific genetic marker (HLA DQ 2.5) that is strongly linked to an increased risk of celiac disease. This discovery is important because it suggests that celiac disease has been present for thousands of years, which can reshape our understanding of the condition's history. Who this helps: This helps researchers and medical professionals understand the long-term history of celiac disease.

PubMed

Deep into the roots of the Libyan Tuareg: a genetic survey of their paternal heritage.

2011

American journal of physical anthropology

Ottoni C, Larmuseau MH, Vanderheyden N, Martínez-Labarga C, Primativo G +3 more

Plain English
This study examined the genetic heritage of the Libyan Tuareg people, focusing on their paternal lineage. Researchers analyzed DNA from 47 individuals and found that a predominant part of their Y-chromosome comes from northwest Africa, with specific markers identified in 87% of the samples. Additionally, there was evidence of recent genetic contributions from south-Saharan Africa, possibly due to historical interactions involving slavery or tribal mixing. Understanding these genetic roots helps shed light on the history and culture of the Tuareg people. Who this helps: This benefits researchers studying African genetics and history, as well as the Tuareg community themselves.

PubMed

Tracing ancient human migration.

2010

Annals of human biology

Rickards O

PubMed

Mitochondrial DNA variation in an isolated area of Central Italy.

2010

Annals of human biology

Messina F, Scorrano G, Labarga CM, Rolfo MF, Rickards O

Plain English
This study looked at the genetic history of two mountain communities in Central Italy, Jenne and Vallepietra, to see how their DNA has changed over time. Researchers analyzed the DNA of 124 individuals from these areas and discovered that Vallepietra has a surprisingly high percentage (71.3%) of DNA typical of groups from Near Eastern and South-Western Asia, indicating limited mixing with other populations. This is important because it shows how geography can preserve unique genetic traits in isolated communities. Who this helps: This research benefits geneticists, historians, and anyone interested in understanding population genetics and ancestry.

PubMed

Mitochondrial haplogroup H1 in north Africa: an early holocene arrival from Iberia.

2010

PloS one

Ottoni C, Primativo G, Hooshiar Kashani B, Achilli A, Martínez-Labarga C +3 more

Plain English
This study examined the mitochondrial DNA of the Tuareg people in Libya and found that a specific genetic type, called haplogroup H1, arrived from Europe around 8,000 to 9,000 years ago. The researchers discovered that while H1 is common in Western Europe, the Tuareg show unique local branches of this genetic type, which can differ significantly even among nearby communities. Understanding this genetic history is important as it sheds light on human migration patterns and the effects of climate change on population movement in ancient times. Who this helps: This helps researchers studying human genetics and migration history.

PubMed

Publication data sourced from PubMed . Plain-English summaries generated by AI. Not medical advice.