Division of Interventional Radiology, Columbia University Irving Medical Center, New York, New York.; Morgan Stanley Children's Hospital of New York, New York, New York.
P Schlossberg studies complications that can arise after liver transplants in children, particularly focusing on issues related to bile duct strictures. Bile duct strictures, which are narrow passages that can occur after surgery, can lead to significant health problems for young patients. To address this, Schlossberg has researched a method called biliary dilation, which is a procedure used to open up these strictures. Their work emphasizes a structured approach involving multiple sessions to improve recovery for children who have undergone liver transplants.
Key findings
The standardized three-session biliary dilation protocol significantly reduced total drainage time for pediatric patients.
Compared to traditional methods, this structured approach improved overall patient outcomes after liver transplant complications.
Children who followed the three-session protocol faced fewer repeated interventions.
Frequently asked questions
Does Dr. Schlossberg study liver transplants?
Yes, Dr. Schlossberg focuses on complications related to liver transplants in pediatric patients.
What is biliary dilation?
Biliary dilation is a procedure used to widen narrowed bile ducts following surgery, which can relieve complications.
How does Dr. Schlossberg's work help children after liver transplants?
Their research has led to a structured protocol that reduces the need for multiple medical interventions, resulting in better health outcomes for kids.
Publications in plain English
Partial Splenic Embolization Is a Safe and Effective Alternative in the Management of Portal Hypertension in Children.
2019
Journal of pediatric gastroenterology and nutrition
Vittorio J, Orellana K, Martinez M, Ovchinsky N, Schlossberg P +2 more
Plain English This study looked at a treatment called partial splenic embolization (PSE) for children with portal hypertension, which can cause serious bleeding and low platelet counts. Researchers reviewed the results for 26 patients aged between 18 months and 20 years who received PSE between 2010 and 2017. They found that 80% of the children had improved platelet counts after the treatment, and only a few needed further therapies for related complications, making PSE a safe and effective option that helps preserve spleen function.
Who this helps: This treatment benefits children with portal hypertension and their healthcare providers.
Evaluation of a three-session biliary dilation protocol following transplant-related biliary stricture in pediatric patients.
2019
Pediatric transplantation
Reis SP, Bruestle K, Brejt S, Tulin-Silver S, Frenkel J +8 more
Plain English Bile duct strictures are a common complication after pediatric liver transplant, often requiring repeated procedures. This study tested a structured three-session dilation protocol and found it reduced total drainage time and improved outcomes compared to less systematic approaches. A standardized biliary dilation protocol can spare children multiple interventions.
Combined Percutaneous Transrenal and Transfemoral Endovascular Recanalization and Angioplastic Reconstruction of a Disrupted Transplant Renal Artery Stent: A Novel Salvage Technique.
2017
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons
Carpenter DJ, Mohan S, Ratner LE, Schlossberg P
Plain English This study focused on a new method for fixing a blocked kidney artery stent that had become damaged after a kidney transplant. The researchers succeeded in repairing the stent using a combination of approaches that included accessing the artery through the kidney itself, which helped to restore normal blood flow. This led to improvements in the patient's kidney function, reducing blood pressure and swelling in the legs.
Who this helps: This technique benefits kidney transplant patients who experience issues with their artery stents.
Abnormal renal parenchyma accumulation ofI MIBG in a child with renal artery stenosis.
2017
Clinical imaging
Yeh R, Mohammed A, Margolin A, Schlossberg P, Ayyala RS
Plain English This study looked at a child with high blood pressure caused by a narrowed renal artery, known as renal artery stenosis (RAS). The researchers found abnormal results on a specific imaging test (I MIBG scan) that can sometimes lead to a wrong diagnosis when RAS is present. Understanding this connection is important because it helps doctors identify RAS more accurately, which can lead to better treatment for the child.
Who this helps: This helps doctors and pediatric patients with hypertension.
Renal Transplant Arterial Stenosis Treated With Bare-Metal Versus Drug-Eluting Stents: Comparison of Treatment Outcomes.
2015
Transplantation proceedings
Hanna RF, Hao F, Kraus CF, Mitsopoulos G, Goldstein GE +5 more
Plain English This study looked at how well two types of stents—bare-metal stents (BMS) and drug-eluting stents (DES)—work for treating narrowing in arteries after kidney transplants. Researchers reviewed records of 18 patients and found that those with BMS needed more follow-up procedures (4 out of 11) compared to those with DES (none of the 7). However, the differences in outcomes like blood pressure and kidney function changes were not significant, suggesting both stents work similarly overall.
Who this helps: This information benefits doctors and kidney transplant patients by providing insights into treatment options.
Image-guided esophageal anastomosis in esophageal atresia.
2012
Journal of pediatric surgery
Garcia AV, Thirumoorthi AS, Traina JM, Schlossberg P, Sheynzon V +1 more
Plain English Researchers studied a new method for connecting the esophagus in infants with a condition called esophageal atresia, especially those with serious heart problems. They had a case where a baby couldn't safely have standard surgery because of heart issues, but were able to successfully connect the esophagus using an image-guided technique instead. This method could be a safer option for other high-risk infants needing similar surgeries.
Who this helps: This helps infants with esophageal atresia, especially those with complex heart conditions.
Chen Q, Tack C, Morcos M, Ruggiero M, Schlossberg P +3 more
Plain English This study focused on a patient with a rare connection between an artery and vein in the abdomen that caused significant health issues like weight loss and abdominal pain. The researchers successfully used special coils and glue to block this abnormal connection, leading to immediate relief from symptoms, with the patient feeling completely better after three months. This is important because it shows a new, effective way to treat this condition, improving patients' quality of life.
Who this helps: Patients suffering from arterioportal fistulas.
MR imaging as the sole preoperative imaging modality for right hepatectomy: a prospective study of living adult-to-adult liver donor candidates.
2001
AJR. American journal of roentgenology
Lee VS, Morgan GR, Teperman LW, John D, Diflo T +7 more
Plain English This study looked at whether MRI can be the only imaging test needed before liver surgery for adult donors. They examined 25 candidates and found that MRI identified issues in 36% of them, leading to nine people being ruled out as donors due to various concerns, while confirming helpful information in the others. This is important because it shows that MRI can effectively evaluate liver donors, but better methods are still needed to see the bile ducts clearly.
Who this helps: This helps patients needing liver transplants and the doctors selecting suitable donors.
MR-guided needle aspiration biopsies of hepatic masses using a closed bore magnet.
1998
Journal of computer assisted tomography
Rofsky NM, Yang BM, Schlossberg P, Goldenberg A, Teperman LW +1 more
Plain English This study looked at a new way to perform liver biopsies using an MRI machine to guide the needle. The researchers conducted 14 biopsies on 11 patients, achieving a 93% success rate in getting useful information from the samples. They confirmed liver cancer in 6 cases and found metastases in 3, demonstrating that this method can accurately target small liver lesions even when other imaging methods failed to provide clear results.
Who this helps: Patients with liver masses that are hard to diagnose.
Extension of a secondary adrenal neoplasm into the inferior vena cava.
1994
Abdominal imaging
Gollub MJ, Bosniak MA, Schlossberg P, Chachoua A
Plain English This study looked at a rare case where cancer that originated in another part of the body spread to the adrenal gland and then extended into a major blood vessel called the inferior vena cava. This type of cancer spreading is not commonly documented, making this case significant. Understanding these cases better is important as it can help improve diagnosis and treatment options for patients with similar conditions.
Who this helps: This helps patients with metastatic cancer and their doctors.
Adrenal myelolipomas: CT appearance with tiny amounts of fat and punctate calcification.
1989
Urologic radiology
Rofsky NM, Bosniak MA, Megibow AJ, Schlossberg P
Plain English This study looked at five cases of adrenal myelolipomas, which are tumors found on the adrenal glands. The researchers found that these tumors showed very small amounts of fat and tiny spots of calcification on CT scans, which is a less common appearance. Recognizing these specific features in CT images is important because it helps doctors accurately diagnose this type of tumor.
Who this helps: This helps radiologists and pathologists in diagnosing adrenal tumors.
Management of symptomatic renal angiomyolipomas by embolization.
1984
Urologic radiology
Rosen RJ, Schlossberg P, Roven SJ, Rothberg M
Plain English This study looked at how to treat kidney tumors called renal angiomyolipomas, which are usually harmless but can cause symptoms, especially in patients with a condition called tuberous sclerosis. The researchers treated two patients by blocking the blood supply to these tumors, allowing them to manage the tumors while preserving healthy kidney tissue. This approach is important because it helps patients avoid more invasive surgeries and maintain kidney function.
Who this helps: This benefits patients with symptomatic renal angiomyolipomas, particularly those with tuberous sclerosis.