Ryan L Boyd studies how language and communication affect mental health, relationships, and interactions with technology. He has developed tools like PsychAdapter, which modifies AI to better reflect individual personalities and mental health characteristics, improving personal interactions in therapy. Boyd also examines how communication patterns change with age, particularly in couples, and how AI can help foster emotional connections in relationships. His research extends to assessing resilience through language analysis, and he investigates the impact of societal events on language and emotions, shedding light on how our experiences shape the way we communicate.
Key findings
PsychAdapter accurately matched Big Five personality traits 87.3% of the time and recognized levels of depression and life satisfaction with 96.7% accuracy.
In a study of older couples, it was found that they used more 'we' language, indicating stronger togetherness, yet expressed fewer positive emotions compared to younger couples.
High resilience individuals showed an average decrease in PTSD symptoms of about 0.21 points over four years, indicating the importance of resilience in recovery from trauma.
New CAR-T cells targeting TAG-72 and CD30 showed effectiveness in destroying tumors, providing new treatment options for patients with aggressive T cell malignancies.
Using CRISPR to enhance CAR-T cells for ovarian cancer provided significant improvements, allowing for extended time without tumor regrowth—up to 100 days compared to 40 days with regular CAR-T cells.
Frequently asked questions
Does Dr. Ryan L Boyd study mental health?
Yes, he focuses on how language and communication influence mental health and has developed tools to help assess and understand these aspects.
What treatments has Dr. Boyd researched?
He has explored innovative treatments using CAR-T therapy for cancers and tools like PsychAdapter to improve mental health assessments.
Is Dr. Boyd's work relevant to older adults?
Yes, his research on communication in couples includes insights that help understand and support relationships in older age.
How does AI factor into Dr. Boyd's research?
He investigates how AI can enhance emotional connections in human interactions and improve mental health support.
What is the significance of Dr. Boyd's findings on resilience?
His work shows that resilience, as measured through language patterns, plays a crucial role in recovery from traumatic experiences.
Publications in plain English
Measuring resilience using language modeling: A computational approach to observing resilience.
Plain English This research focused on developing a new method to measure resilience, which helps people cope after difficult events, using a computerized approach called ReLM (resilience using language modeling). The study examined 1,859 voicemails from survivors of the September 11 attacks and found that those identified as highly resilient experienced significant improvements in post-traumatic stress disorder (PTSD) symptoms over four years. Specifically, the study showed that the highly resilient group had an average decrease in PTSD symptoms of about 0.21 points, indicating that resilience plays a crucial role in recovery from trauma.
Who this helps: This assists patients, particularly those recovering from trauma, and healthcare providers seeking to support their mental health.
Artificial Intelligence and the Psychology of Human Connection.
2026
Perspectives on psychological science : a journal of the Association for Psychological Science
Boyd RL, Markowitz DM
Plain English This study looks at how artificial intelligence (AI) affects human relationships and communication. It introduces a new framework, called MIRA, which identifies two roles for AI: as a companion during conversations and as a tool that shapes how people interact with each other. The researchers found that AI can help create emotional connections and build trust in relationships, which is important as AI becomes more common in everyday social situations.
Who this helps: This benefits patients, doctors, and anyone using AI for communication and social interaction.
Everyday conversations of younger and older couples: Age differences in we-ness, emotions, and conversation topics.
2026
Psychology and aging
Meier T, Huber ZM, Dworakowski O, Haase CM, Boyd RL +1 more
Plain English This study looked at how younger (ages 18-33) and older couples (ages 57-87) communicate in their daily lives over 21 days. Researchers found that older couples used more "we" language, indicating a stronger sense of togetherness, but expressed fewer positive emotions, such as laughter and upbeat words. This matters because it shows how emotional connection and interaction styles change with age, which can inform how we understand and support relationships in later life.
Who this helps: This helps patients and couples, particularly those in older age groups.
PsychAdapter: adapting LLMs to reflect traits, personality, and mental health.
2026
NPJ artificial intelligence
Vu H, Nguyen HA, Ganesan AV, Juhng S, Kjell ONE +6 more
Plain English This study introduced a new tool called PsychAdapter that modifies AI language models to create text that reflects individual personality traits and mental health characteristics. In tests, it accurately matched the Big Five personality traits 87.3% of the time and recognized levels of depression and life satisfaction with 96.7% accuracy. This is important because it helps create more personalized and relevant interactions in mental health assessments and support.
Who this helps: Patients and mental health professionals.
Plain English This study looked at how advancements in natural language processing (NLP) are changing the way researchers in various fields, like psychology and sociology, analyze human thoughts and behaviors. The authors argue that over the next 3-5 years, the direction of NLP research will significantly shape our understanding of social interactions and human experiences, highlighting the need to combine NLP findings with established behavioral science theories. This matters because it will ensure that language analysis tools are not only effective but also ethically responsible in addressing important social questions.
Who this helps: This helps researchers, clinicians, and policymakers who want to better understand human behavior.
Exploring adult hearing aid user experiences: meaning extraction methods, content patterns, and associations with demographic and outcome variables.
2025
International journal of audiology
Oosthuizen I, Swanepoel W, Boyd RL, Pennebaker JW, Launer S +1 more
Plain English This study looked at the experiences of adults using hearing aids by analyzing their open-ended feedback. Researchers found six important themes in these experiences, including changes in life due to hearing aids and their impact on social situations and quality of life. Notably, people who had more difficulty hearing also reported greater changes in their life and social interactions.
Who this helps: This benefits hearing aid users by providing insights that can improve their experience and care.
Analysis of social media language reveals the psychological interaction of three successive upheavals.
2025
Scientific reports
Mesquiti S, Seraj S, Weyland AH, Ashokkumar A, Boyd RL +2 more
Plain English This study examined how three major events—COVID-19, the Black Lives Matter protests, and the Supreme Court decision on Roe v. Wade—changed the way people expressed themselves on social media. Researchers analyzed over 45 million Reddit comments and 889,000 news headlines and found that after each event, people's language shifted significantly. For example, during the pandemic, people became more self-focused and anxious, while the BLM protests and the Roe v. Wade decision led to more anger and a sense of collective action. This shows how major events affect our emotions and discussions in different ways.
Who this helps: This helps researchers, social media analysts, and public health officials understand how societal events influence public sentiment.
CRISPR-Cas9 knockout of DGKα/ζ improves the anti-tumor activities of TAG-72 CAR-T cells in ovarian cancer.
2025
Molecular therapy. Oncology
Evtimov VJ, Nguyen NN, Hammett MV, Pupovac A, Hudson PJ +6 more
Plain English Researchers looked at a new way to improve CAR-T cell therapy for ovarian cancer by using a technique called CRISPR to knock out certain enzymes that suppress T-cell activity. They found that these specially engineered CAR-T cells were able to kill cancer cells marked by the TAG-72 protein and could keep tumors from returning for up to 100 days, while regular CAR-T cells showed tumor regrowth after about 40 days. This work is important because it may lead to more effective treatments for difficult-to-treat cancers like ovarian cancer.
Who this helps: This helps patients with ovarian cancer by providing potentially better treatment options.
Automating the Detection of Linguistic Intergroup Bias Through Computerized Language Analysis.
2025
Journal of language and social psychology
Collins KA, Boyd RL
Plain English This study focused on finding a faster and easier way to detect linguistic bias in writing, specifically how different groups describe behavior. Researchers developed an automated system that closely matched manual coding results, showing that automated methods can accurately identify linguistic bias without the need for intensive human effort. This is important because it allows for quicker assessment of language, helping to uncover hidden attitudes that affect communication across group boundaries.
Who this helps: This helps researchers and organizations analyzing language in social contexts.
Psychosocial dynamics of suicidality and nonsuicidal self-injury: a digital linguistic perspective.
2025
Npj mental health research
Entwistle C, Hoemann K, Nightingale SJ, Boyd RL
Plain English This study examined how people with borderline personality disorder (BPD) talk about self-harm—including both suicidal thoughts and non-suicidal self-injury—by analyzing over 66,000 posts from 992 users on a Reddit forum dedicated to BPD. The researchers found specific patterns in the language used, which highlighted how individuals in this online community interact around these behaviors. Understanding these dynamics is crucial because it can help improve support and treatment for those at risk of self-harm.
Who this helps: This helps patients with borderline personality disorder and mental health professionals.
Engineering TAG-72 and CD30 CAR-T Cells for T Cell Malignancies.
2025
Immunological investigations
To V, Evtimov VJ, Shu R, Pupovac A, Boyd RL +1 more
Plain English This study looked at new types of CAR-T cells designed to fight T cell malignancies, which are aggressive cancers with poor outcomes. The researchers created CAR-T cells that target specific proteins on tumor cells, including TAG-72 and CD30, and found that these cells were effective in destroying tumors that expressed those proteins. They discovered that using a combination of these CAR-T cells could be especially beneficial when the targeted proteins were present in lower amounts.
Who this helps: This research helps patients with T cell cancers by providing new treatment options.
Clear aligner orthodontic treatment: An international modified Delphi consensus study.
2025
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics
Arveda N, Calza M, Castroflorio T, Garino F, Giancotti A +32 more
Plain English This study gathered opinions from 36 orthodontic experts worldwide to create a clear understanding of how effective clear aligners are for teeth straightening. After three rounds of discussion and voting, they reached agreement on 47 key points about both the mechanics of aligners and factors outside of clinical settings that affect their use. This matters because it helps improve the guidance for using aligners in orthodontics, ensuring that both patients and providers have a clear framework for treatment expectations.
Who this helps: Patients and orthodontic providers.
Capturing Human Cognitive Styles with Language: Towards an Experimental Evaluation Paradigm.
2025
Proceedings of the conference. Association for Computational Linguistics. North American Chapter. Meeting
Varadarajan V, Mahwish S, Liu X, Buffolino J, Luhmann CC +2 more
Plain English Researchers studied how the way people talk about their decisions reflects their thinking styles. They found that certain language patterns can accurately predict how someone makes choices, achieving about 80% accuracy in assessments. This is important because it shows that analyzing language can provide insights into a person's cognitive processes, potentially leading to better understanding and support in decision-making contexts.
Who this helps: This helps patients and psychologists understand and improve decision-making strategies.
Unifying the Extremes: Developing a Unified Model for Detecting and Predicting Extremist Traits and Radicalization.
2025
Proceedings of the ... International AAAI Conference on Weblogs and Social Media. International AAAI Conference on Weblogs and Social Media
Lahnala A, Varadarajan V, Flek L, Schwartz HA, Boyd RL
Plain English This study explored how to identify and predict extremist behaviors in people using social media. Researchers created a method to analyze online discussions, identifying 11 key traits associated with extremism. They found that their approach could predict whether someone would join a radical group, like the incel community, with increasing accuracy—up to 90% accuracy three to four months before they actually joined. This research is important because it helps identify potential extremists early, which can assist in prevention efforts.
Who this helps: This helps mental health professionals, law enforcement, and community outreach programs.
Plain English This study looked at improving a type of cancer treatment called CAR-NK therapy, which uses natural killer cells to target and kill tumor cells. The researchers found that while CAR-NK cells have potential benefits, they struggle to work effectively against solid tumors due to challenges like a complicated tumor environment and the body's immune defenses. Finding ways to enhance CAR-NK therapy is crucial as it could lead to better treatment options for patients with solid tumors.
Who this helps: Patients with solid tumors.
Comparing the language style of heads of state in the US, UK, Germany and Switzerland during COVID-19.
2024
Scientific reports
Dworakowski O, Meier T, Mehl MR, Pennebaker JW, Boyd RL +1 more
Plain English This study looked at how leaders from the US, UK, Germany, and Switzerland communicated during the early stages of the COVID-19 pandemic by analyzing their speeches and press conferences. They found that Trump used a lot of positive language, Merkel focused on community, while Johnson and the Swiss leaders emphasized analytical thinking. Understanding these communication styles is important as it shows how different approaches can affect public response during a crisis.
Who this helps: This helps citizens and policymakers understand the impact of leadership communication on public health responses.
HIV, multimorbidity, and health-related quality of life in rural KwaZulu-Natal, South Africa: A population-based study.
2024
PloS one
Stanton AM, Boyd RL, O'Cleirigh C, Olivier S, Dolotina B +13 more
Plain English In this study conducted in rural KwaZulu-Natal, South Africa, researchers looked at how having multiple health conditions (known as multimorbidity) affects people's quality of life, particularly for those with HIV and other diseases like diabetes and high blood pressure. They found that having more diseases generally worsened people's perceived health, with a significant negative impact measured at -0.060. Interestingly, people with well-controlled HIV reported better health compared to those with non-communicable diseases, which were linked to poorer quality of life. This is important because it highlights the need for effective disease management, especially for HIV and chronic conditions, to enhance patients' overall well-being.
Who this helps: This benefits patients living with HIV and other chronic conditions.
Vertical and transverse treatment effects of Invisalign First system compared to Hyrax maxillary expanders with fixed appliances in mixed dentition patients.
2024
The Angle orthodontist
Moravedje Torbaty P, Suh H, Tai SK, Baird M, Boyd RL +1 more
Plain English The study compared two orthodontic treatments, the Invisalign First System (IFS) and Hyrax expanders, in children with mixed dentition (a mix of baby and adult teeth). It found that while the Hyrax group had a greater maxillary arch expansion of 4.4 mm versus the IFS group's 2.5 mm, the IFS can still effectively increase arch width. This matters because it shows that IFS can be a less invasive option for mild dental arch expansion.
Who this helps: This research benefits orthodontists and children needing dental expansion treatments.
Evtimov VJ, Hammett MV, Pupovac A, Nguyen NN, Shu R +6 more
Plain English This study looked at a potential treatment for cutaneous T cell lymphoma (CTCL) by targeting a protein called TAG-72, which is found in higher levels in cancer cells compared to healthy ones. Researchers found that TAG-72 was significantly present on T cells from CTCL patients and in their skin lesions, suggesting it could be a good target for therapy. The results showed that custom-made CAR-T cells targeting TAG-72 were able to effectively attack CTCL cells, indicating promise for this approach in treating the disease.
Who this helps: This helps patients with cutaneous T cell lymphoma.
How developments in natural language processing help us in understanding human behaviour.
2024
Nature human behaviour
Mihalcea R, Biester L, Boyd RL, Jin Z, Perez-Rosas V +2 more
Plain English This research paper examines how analyzing language—both spoken and written—can give insights into people's emotions and social behaviors. Over the last 20 years, advances in technology have allowed researchers to develop tools that improve our understanding of human interactions beyond traditional methods like surveys. These language analysis techniques can uncover deeper meanings and patterns in communication, making them a powerful alternative for studying social behavior.
Who this helps: This benefits researchers, psychologists, and anyone interested in understanding human communication and behavior.
Are we listening to every word? Using multiple analytic methods to examine qualitative data.
2024
Cogent mental health
Boyd RL, Morrison NR, Horwitz SD, Maciag R, Travers-Hill E +1 more
Plain English This study looked at how different methods of analyzing interview data can provide new insights into the experiences of paraprofessionals who deliver Brief Psychological Interventions. Researchers used two specific text analysis tools alongside a traditional method and found that each method revealed unique findings—no single approach was enough on its own. This matters because using multiple methods not only enhances the understanding of the data but also validates traditional ways of analyzing qualitative research.
Who this helps: This benefits researchers and practitioners in psychology, particularly those working with paraprofessionals.
Fibroblastic reticular cells provide a supportive niche for lymph node-resident macrophages.
2023
European journal of immunology
D'Rozario J, Knoblich K, Lütge M, Shibayama CP, Cheng HW +12 more
Plain English This study looked at how specific cells called fibroblastic reticular cells (FRCs) help support macrophages, which are important for the immune system, in lymph nodes. The researchers found that when FRCs were removed, there was a quick decrease of macrophages and monocytes—types of immune cells—in the lymph nodes, showing that FRCs are vital for their survival. This matters because understanding how these cells interact could improve immune response and treatments for diseases.
Who this helps: This helps patients with immune system conditions by providing insights that could lead to better therapies.
An exploration of marks/injuries related to BDSM sexual experiences.
2023
Sexual medicine
Drouin M, Hernandez E, Machette A, Garcia JR, Boyd RL
Plain English This study looked at the physical marks and injuries that people get from consensual BDSM (bondage and discipline, dominance and submission, sadomasochism) activities, surveying 513 adults in the U.S. It found that both intentional and unintentional marks, ranging from small scratches to large bruises, are quite common and vary in severity. Importantly, those with more experience in BDSM use safe words more frequently, but they also tend to inflict more marks on their partners.
Who this helps: This research benefits healthcare providers and individuals engaging in BDSM by promoting better understanding and communication regarding potential injuries.
Emotional Granularity is Associated with Daily Experiential Diversity.
2023
Affective science
Hoemann K, Lee Y, Kuppens P, Gendron M, Boyd RL
Plain English This research looked at how people describe their daily experiences and whether this affects how specifically they can identify their emotions. The findings showed that individuals who talked about a wider variety of activities and contexts reported more detailed and nuanced negative emotions. Specifically, those with higher experiential diversity experienced greater emotional granularity on negative feelings, but the same was not consistently true for positive emotions.
Who this helps: This research benefits patients seeking to better understand and manage their emotions.
Short-term stability of anterior open bite treatment with clear aligners in adults.
2023
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics
Suh H, Garnett BS, Mahood K, Boyd RL, Oh H
Plain English This study looked at how stable the correction of anterior open bite (AOB) was in 52 adults treated with clear aligners. They found that, on average, patients improved their bite by 3.3 mm during treatment, and only 6% experienced a relapse after one year, with no significant changes in bite position after retention. This matters because it shows that clear aligners can effectively correct AOB in adults, maintaining the results over time without needing extra devices.
Who this helps: This helps patients with anterior open bite seeking effective orthodontic treatment.
Uncovering the Social-Cognitive Contributors to Social Dysfunction in Borderline Personality Disorder Through Language Analysis.
2023
Journal of personality disorders
Entwistle C, Boyd RL
Plain English This study looked at how the way people with borderline personality disorder (BPD) express themselves in writing relates to their difficulties in personal relationships. Researchers surveyed 530 people and used computer analysis to find four key ways of thinking about relationships that were connected to BPD traits. Understanding these patterns can help improve support for those with BPD by offering insights into their challenges with social interactions.
Who this helps: This benefits patients with borderline personality disorder and the mental health professionals who support them.
Posting patterns in peer online support forums and their associations with emotions and mood in bipolar disorder: Exploratory analysis.
2023
PloS one
Jagfeld G, Lobban F, Davies R, Boyd RL, Rayson P +1 more
Plain English This study looked at how people with bipolar disorder use online support forums on Reddit. Researchers found that two-thirds of nearly 20,000 users post in both mental health (MH) and non-MH subreddits, but those who post in MH spaces expressed more anxiety and sadness. This matters because it shows that people may use these forums to share their struggles, and mental health professionals should be aware that these conversations may not reflect the full range of experiences of all individuals with bipolar disorder.
Who this helps: This helps mental health professionals and patients with bipolar disorder.
Emotion regulation across the lifespan: age differences in intrapersonal and interpersonal strategies for the adjustment to the COVID-19 pandemic in four countries.
2022
Aging & mental health
Dworakowski O, Huber ZM, Meier T, Boyd RL, Horn AB
Plain English This study looked at how people of different ages cope with the emotional stress of the COVID-19 pandemic. Researchers found that older adults (ages 64-88) reported fewer anxiety symptoms related to the pandemic, and this was linked to them engaging in less negative thinking and brooding compared to younger adults (ages 18-29). Specifically, 1,401 participants from the USA, UK, Switzerland, and Germany took part, showing that older adults' more positive adjustment comes from better emotional regulation strategies.
Who this helps: This helps patients, especially older adults, by highlighting effective coping strategies for stress.
Use of open-ended questionnaires to examine the effects of tinnitus and its relation to patient-reported outcome measures.
2022
International journal of audiology
Manchaiah V, Andersson G, Fagelson MA, Boyd RL, Beukes EW
Plain English This study looked at how open-ended questions can help understand the effects of tinnitus, a ringing or buzzing in the ears, by analyzing responses from 336 people. Researchers found that while some answers related to feelings of anxiety and depression, open-ended questions revealed additional insights that standard questionnaires missed. This is important because it shows that using these open-ended questions alongside traditional surveys may provide a better understanding of how tinnitus affects people's lives.
Who this helps: This helps patients with tinnitus by providing better tools for understanding their experiences.
An inclusive, real-world investigation of persuasion in language and verbal behavior.
2022
Journal of computational social science
Ta VP, Boyd RL, Seraj S, Keller A, Griffith C +2 more
Plain English Researchers studied how the way we use language affects our ability to persuade others during online debates. They analyzed messages from a social media platform where users tried to change each other's opinions and found that longer, more analytical messages were more persuasive. Specifically, persuasive messages were often wordier, harder to read, and contained fewer varied words, leading to better chances of changing someone's mind.
Who this helps: This helps anyone looking to improve their persuasive communication, including patients, doctors, and public advocates.
Social Media Discussions Predict Mental Health Consultations on College Campuses.
2022
Scientific reports
Saha K, Yousuf A, Boyd RL, Pennebaker JW, De Choudhury M
Plain English This study looked at how discussions on social media, particularly Reddit, can help predict when college students will seek mental health help. Researchers analyzed over 66,000 posts from a university's Reddit community alongside actual mental health consultations from 2011 to 2016. They found that using social media data to make these predictions was much more accurate, improving their predictions by 41%, which means that monitoring social media can provide important insights into the mental health needs of students.
Who this helps: This benefits college students and mental health professionals.
Online Discussions About Tinnitus: What Can We Learn From Natural Language Processing of Reddit Posts?
2022
American journal of audiology
Manchaiah V, Londero A, Deshpande AK, Revel M, Palacios G +2 more
Plain English This study looked at conversations about tinnitus on Reddit to find out what topics people discuss the most. Researchers analyzed over 101,000 posts and found 16 main themes, such as the causes of tinnitus, ways to manage it, and personal experiences. These findings show that many people with tinnitus rely on online communities for support, indicating a need for better social support options, like support groups.
Who this helps: Patients with tinnitus and their families can benefit from these insights.
Treatment of anterior open bites using non-extraction clear aligner therapy in adult patients.
2022
Korean journal of orthodontics
Suh H, Garnett BS, Mahood K, Mahjoub N, Boyd RL +1 more
Plain English This study looked at how well clear aligners can fix a specific dental issue called "anterior open bite" in adult patients who don't need extractions. Out of 69 patients, 94% ended up with a normal bite after treatment, with an average improvement of 3.3 mm. The results show that clear aligners are effective in addressing this condition, and different types of patients may respond differently to treatment.
Who this helps: This helps adult patients with anterior open bite who are seeking a non-extraction treatment option.
'Against the cult of veganism': Unpacking the social psychology and ideology of anti-vegans.
2022
Appetite
Gregson R, Piazza J, Boyd RL
Plain English This study looked at online communities that oppose veganism, specifically analyzing discussions from a group on Reddit called r/AntiVegan. Over five years, researchers examined about 3,500 posts and 45,500 comments, finding that many members share backgrounds like having previously been vegan and tend to reject scientific information. The study highlights the complexity of their beliefs and how their commitment to the anti-vegan community grows over time, which is important for understanding attitudes toward veganism and improving communication between vegans and non-vegans.
Who this helps: This helps anyone involved in discussions about diet choices, including patients, nutritionists, and advocates for plant-based diets.
Plain English This study explored a new way to deliver CAR-T cell therapy, which is a promising cancer treatment, using tiny gelatin-based gels. The researchers found that CAR-T cells packaged in these gels remained healthy and effective, eliminating cancer cells in lab tests, with over 87% viability after a week. This is important because it offers a more effective approach to treat solid tumors, which are harder to kill with current methods.
Who this helps: This benefits cancer patients, especially those with solid tumors like ovarian cancer.
Comparison between a human judge and automatic landmark identification on digital models.
2022
American journal of orthodontics and dentofacial orthopedics : official publication of the American Association of Orthodontists, its constituent societies, and the American Board of Orthodontics
Dolatabadi N, Boyd RL, Oh H
Plain English This study looked at how well a software program can identify specific points on digital dental models compared to human judges. Researchers found that the software's accuracy was almost as good as that of skilled human judges, with nearly perfect agreement (1.0 for x and y coordinates and 0.98 for z). This is important because it means that automated tools can reliably be used in dental analysis, saving time and potentially improving patient care.
Who this helps: This helps dentists and orthodontists improve their diagnosis and treatment planning.
CAR-T cell development for Cutaneous T cell Lymphoma: current limitations and potential treatment strategies.
2022
Frontiers in immunology
To V, Evtimov VJ, Jenkin G, Pupovac A, Trounson AO +1 more
Plain English This research paper looks at how CAR-T cell therapy, which has been successful for certain blood cancers, faces challenges when used to treat cutaneous T cell lymphoma (CTCL). The study identifies several key problems, including harmful side effects due to the nature of the therapy and the complexity of the tumors, suggesting that new approaches, like targeting multiple cancer markers, could improve treatment effectiveness. This is important because it could lead to better outcomes for patients with CTCL who currently have limited treatment options.
Who this helps: Patients with cutaneous T cell lymphoma.
You Do Not Have to Get through This Alone: Interpersonal Emotion Regulation and Psychosocial Resources during the COVID-19 Pandemic across Four Countries.
2022
International journal of environmental research and public health
Dworakowski O, Huber ZM, Meier T, Boyd RL, Martin M +1 more
Plain English This study looked at how people cope with their emotions by relying on others during the COVID-19 pandemic, and how strong social connections can affect this process. Researchers surveyed 1,401 participants from the USA, UK, Germany, and Switzerland and found that using unhealthy ways to manage emotions led to more symptoms of depression and anxiety, especially in those with less social support. This is important because it highlights the need for strong social connections to help improve mental health during tough times.
Who this helps: This helps patients struggling with mental health issues during and after the pandemic.
Engineered CAR-T cells targeting TAG-72 and CD47 in ovarian cancer.
2021
Molecular therapy oncolytics
Shu R, Evtimov VJ, Hammett MV, Nguyen NN, Zhuang J +5 more
Plain English Researchers studied a new type of treatment for ovarian cancer using engineered immune cells, called CAR-T cells, which target two specific markers found in tumors: TAG-72 and CD47. They found that their dual approach effectively increased the ability of these CAR-T cells to attack and eliminate cancer cells while reducing harm to healthy tissue. This matters because it offers a promising way to improve treatment outcomes for patients with ovarian cancer and potentially other similar tumors.
Who this helps: This helps patients with ovarian cancer and similar cancers by providing a potentially more effective treatment option.
Natural Language Analysis and the Psychology of Verbal Behavior: The Past, Present, and Future States of the Field.
2021
Journal of language and social psychology
Boyd RL, Schwartz HA
Plain English This paper examines how people interpret the words others use to understand their psychological traits and how this research has changed over time. It highlights that although language analysis has had successes, there are also significant gaps and challenges in the field, especially with the growth of new technology that could enhance understanding. This work is important because it suggests ways to improve how we analyze language, which can lead to better insights into human behavior.
Who this helps: This benefits researchers, psychologists, and anyone interested in understanding human psychology through language.
Plain English Researchers analyzed 526 Reddit posts about sudden sensorineural hearing loss to understand how people discuss their experiences and share information online. They found that a substantial number of posts (36%) focused on treatment options, while others shared personal experiences (34%) and described symptoms (31%). This research highlights the importance of online communities for those affected by sudden hearing loss, helping healthcare providers better understand their patients' concerns and needs.
Who this helps: This benefits patients seeking support and doctors looking to improve communication with them.
Dirty laundry: The nature and substance of seeking relationship help from strangers online.
2021
Journal of social and personal relationships
Entwistle C, Horn AB, Meier T, Boyd RL
Plain English This study looked at how people seek relationship help online, specifically using data from over 184,000 posts on Reddit. Researchers found that men are increasingly turning to online platforms for support, discussing their emotions and relationship challenges more openly than in traditional settings. This matters because it reveals a broader view of relationship problems in the general population, showing that help-seeking behaviors can differ significantly by gender.
Who this helps: This helps individuals struggling with relationships and mental health professionals seeking to understand their clients better.
Applied Behavior Analysis as Treatment for Autism Spectrum Disorders: Topic Modeling and Linguistic Analysis of Reddit Posts.
2021
Frontiers in rehabilitation sciences
Bellon-Harn ML, Boyd RL, Manchaiah V
Plain English This study examined discussions on Reddit about applied behavior analysis (ABA) therapy for children with autism. Researchers identified 11 key themes, such as personal experiences and opinions, with users often sharing intimate stories rather than clinical or scientific information. Understanding these discussions is important because it can help professionals provide better support and information for families considering ABA treatment.
Who this helps: Families of children with autism.
Deep into that darkness peering: A computational analysis of the role of depression in Edgar Allan Poe's life and death.
2020
Journal of affective disorders
Dean HJ, Boyd RL
Plain English This study looked at the role of depression in the life and death of writer Edgar Allan Poe by analyzing his letters, poems, and short stories. Researchers found hints of depression in his writings, particularly during his most successful years and after the death of his wife, but they did not find evidence to support that depression caused his death or that he had consistent patterns of depressive episodes. Understanding how emotional struggles showed up in Poe's language helps us learn more about how life events can impact mental health.
Who this helps: This helps doctors and mental health professionals better understand the relationship between life experiences and emotional well-being.
The narrative arc: Revealing core narrative structures through text analysis.
2020
Science advances
Boyd RL, Blackburn KG, Pennebaker JW
Plain English This study examined the common structures found in different types of narratives, analyzing both traditional stories like novels and scripts (around 40,000) as well as nontraditional formats such as newspaper articles and TED talks (about 20,000). Researchers found that traditional narratives follow a consistent pattern involving three main elements: setting the scene, advancing the plot, and creating emotional tension, but this structure didn't seem to affect how popular the stories were. Nontraditional narratives showed different structural patterns, highlighting the unique way information is shared in these formats.
Who this helps: This benefits writers, educators, and anyone interested in understanding how stories and information are communicated effectively.
Natural emotion vocabularies as windows on distress and well-being.
2020
Nature communications
Vine V, Boyd RL, Pennebaker JW
Plain English This research looked at how the variety of emotion words people use in their writing is related to their emotional health. It found that college students and blog writers with a larger range of negative emotion words reported feeling more distressed and less physically healthy, while those with a broader range of positive emotion words generally felt happier and were in better health. This is important because it shows that the way we express our emotions can reflect our mental and physical well-being.
Who this helps: This helps patients and mental health professionals by providing insights into emotional expression and health.
Stereotyping in the digital age: Male language is "ingenious", female language is "beautiful" - and popular.
2020
PloS one
Meier T, Boyd RL, Mehl MR, Milek A, Pennebaker JW +3 more
Plain English This study looked at how the language used in TED Talks reflects gender and age stereotypes and affects how popular those talks become. Researchers analyzed 1,095 TED Talks and found that talks with more traditionally "female" language styles received more views and better ratings than those with "male" language. Specifically, female language was associated with higher popularity, showing that warmth in communication, often linked to female speakers, was especially effective in engaging audiences.
Who this helps: This helps speakers, especially women, who can use language strategies to maximize their impact and reach.