S Monzawa studies schistosomiasis, which is caused by parasitic worms that infect the body and can lead to significant liver problems. Specifically, they investigate how this infection can result in liver scarring and cirrhosis, conditions that deteriorate liver function. Monzawa's research highlights distinctive patterns of liver damage observed through medical imaging, which can help in diagnosing and managing the disease. They aim to understand the complications that arise from the infection, such as liver enlargement, potential liver failure, and increased blood pressure in liver blood vessels.
Key findings
Schistosomiasis can lead to liver scarring represented as either thick bands or a 'turtle-back' pattern on imaging.
The infection often results in an enlarged liver and spleen, impacting overall health.
High blood pressure in the liver's blood vessels is a key complication associated with schistosomiasis.
Frequently asked questions
Does Dr. Monzawa study schistosomiasis?
Yes, Dr. Monzawa specializes in researching schistosomiasis and its effects on the liver.
What complications can arise from schistosomiasis?
Schistosomiasis can lead to serious complications such as liver failure, enlarged liver and spleen, and high blood pressure in the liver's blood vessels.
What patterns of liver damage does Dr. Monzawa find in schistosomiasis?
Dr. Monzawa identifies two main patterns on medical imaging: thick bands around liver blood vessels and a distinctive 'turtle-back' pattern of scarring.
Publications in plain English
Investigation of imaging features in contrast-enhanced magnetic resonance imaging of benign and malignant breast lesions.
2024
Japanese journal of radiology
Kubota K, Fujioka T, Tateishi U, Mori M, Yashima Y +13 more
Plain English This study looked at how effective a special type of breast MRI, using a contrast agent called gadobutrol, is at telling the difference between benign (non-cancerous) and malignant (cancerous) breast lesions. Researchers analyzed data from 200 women, half with benign lesions and half with malignant ones, and found that key factors such as age, where the lesion is located, its shape, and how much it lights up in the scan could help predict whether a lesion is benign or malignant. The study showed that the new approach significantly improved diagnostic accuracy, with scores indicating a 92.5% accuracy for masses and 82.9% for non-mass enhancements, which could reduce unnecessary biopsies.
Who this helps: This benefits patients by improving the accuracy of breast cancer diagnostics.
Duodenal ulcer bleeding from a branch of the middle colic artery: A case report.
2023
Medicine
Shishido Y, Mitsuoka E, Tanigawa Y, Ooki H, Shio S +3 more
Plain English This study looked at a rare case of a 55-year-old man who experienced severe bleeding from a duodenal ulcer that was linked to an unusual branch of a blood vessel called the middle colic artery. After the patient had significant bleeding, doctors used a special procedure to block the bleeding vessels, which successfully stopped the hemorrhage. The patient recovered well and went on to have surgery for a related issue two weeks later, highlighting the importance of careful examination to find all potential sources of upper gastrointestinal bleeding.
Who this helps: This information benefits doctors and patients dealing with severe gastrointestinal bleeding.
Impact of background parenchymal enhancement levels on the diagnosis of contrast-enhanced digital mammography in evaluations of breast cancer: comparison with contrast-enhanced breast MRI.
2022
Breast cancer (Tokyo, Japan)
Yuen S, Monzawa S, Gose A, Yanai S, Yata Y +4 more
Plain English This study compared two imaging techniques, contrast-enhanced digital mammography (CEDM) and breast MRI, to see which is better at diagnosing breast cancer, especially based on how much background tissue enhancement is present. The results showed that CEDM was more accurate than MRI in women with minimal to mild tissue enhancement, with a sensitivity of 90.8% compared to 90.0% for MRI, and specificity of 91.5% versus 71.0%. This matters because using the more effective method can lead to better cancer detection and treatment for patients.
Who this helps: This helps women undergoing breast cancer evaluations and their healthcare providers.
The association between MRI findings and breast cancer subtypes: focused on the combination patterns on diffusion-weighted and T2-weighted images.
2020
Breast cancer (Tokyo, Japan)
Yuen S, Monzawa S, Yanai S, Matsumoto H, Yata Y +5 more
Plain English This study looked at MRI scans of 280 breast cancer patients to see how different imaging patterns related to specific types of breast cancer. They found that a certain pattern on the diffusion-weighted images (DWI) was more common in Luminal A-like cancers (67.1%), while a different pattern indicating potential tumor necrosis was dominant in triple-negative cancers (75%). Understanding these associations helps doctors tailor treatments based on the cancer subtype.
Who this helps: This benefits patients by guiding personalized treatment options based on their cancer characteristics.
The essence of the Japan Radiological Society/Japanese College of Radiology Imaging Guideline.
2016
Japanese journal of radiology
Yamashita Y, Murayama S, Okada M, Watanabe Y, Kataoka M +19 more
Plain English This study focused on creating new guidelines for diagnostic imaging to improve the quality and safety of medical examinations in Japan. The Japan Radiological Society and the Japanese College of Radiology developed the largest set of guidelines for imaging, which includes 152 clinical questions to address common issues and nine key areas of imaging techniques. These guidelines aim to ensure that doctors use imaging appropriately, minimizing unnecessary tests and exposure to radiation.
Who this helps: This benefits patients and doctors by promoting safer and more efficient diagnostic practices.
Pictorial review of orthotopic neobladder reconstruction: indication, normal postsurgical anatomy, and complications.
2016
Abdominal radiology (New York)
Kubota H, Takahashi S, Monzawa S, Yuasa N, Endo T +3 more
Plain English This study looked at a surgical method called orthotopic neobladder reconstruction, which is often used after bladder cancer surgery to help patients urinate normally. The researchers found that while this method can improve patients' quality of life, it also carries risks of various complications, including urine leakage and infections. Understanding the normal anatomy after the surgery and how to spot complications using imaging techniques like CT scans or MRIs is crucial for preventing and addressing problems after the operation.
Who this helps: This benefits patients recovering from bladder cancer surgery and their doctors.
Imaging of metastases from breast cancer to uncommon sites: a pictorial review.
2016
Japanese journal of radiology
Toguchi M, Matsuki M, Numoto I, Tsurusaki M, Imaoka I +6 more
Plain English This research paper looks at how breast cancer can spread to unusual parts of the body after initial treatment. The authors found that while breast cancer commonly spreads to places like the bones, lungs, and liver, it can also affect more uncommon areas. Recognizing these unusual metastases early is important because it can lead to better treatment outcomes for patients.
Who this helps: Patients with breast cancer who may face uncommon spread of their disease.
Incidental detection of clinically unexpected breast lesions by computed tomography.
2013
Acta radiologica (Stockholm, Sweden : 1987)
Monzawa S, Washio T, Yasuoka R, Mitsuo M, Kadotani Y +1 more
Plain English This study looked at how often unexpected breast abnormalities are found during routine body scans using computed tomography (CT) in nearly 3,000 women. Researchers discovered 32 unexpected breast lesions in 31 patients, with 10 of these being cancer, leading to a cancer rate of 31% among the found lesions. This is important because it shows that CT scans can reveal otherwise hidden breast cancers, which means doctors should routinely check for these abnormalities during CT scans.
Who this helps: This helps patients by increasing the chances of early cancer detection.
Mucinous carcinoma of the breast: MRI features of pure and mixed forms with histopathologic correlation.
2009
AJR. American journal of roentgenology
Monzawa S, Yokokawa M, Sakuma T, Takao S, Hirokaga K +2 more
Plain English This study looked at different types of mucinous carcinoma, a specific breast cancer, by using MRI scans to see how they appear. Researchers examined 20 tumors in total, finding that 14 pure mucinous tumors showed very high signal intensity on MRI, which helps in identifying them. Knowing the differences between pure and mixed mucinous carcinoma is important because mixed types tend to spread to lymph nodes more often and generally have a worse outlook for patients.
Who this helps: This helps doctors diagnose and treat breast cancer patients more effectively.
Diagnostic performance of fluorodeoxyglucose-positron emission tomography/computed tomography of breast cancer in detecting axillary lymph node metastasis: comparison with ultrasonography and contrast-enhanced CT.
2009
Annals of nuclear medicine
Monzawa S, Adachi S, Suzuki K, Hirokaga K, Takao S +2 more
Plain English This study looked at how well a type of imaging called PET/CT can detect cancer spread to lymph nodes in the armpit in breast cancer patients, comparing it with ultrasound and enhanced CT scans. Out of 50 patients, 15 had cancer spread confirmed, but PET/CT only found this in 3 of those cases, showing a sensitivity of just 20%, while ultrasound had a sensitivity of 33%. These findings highlight that PET/CT is not as effective as the other methods for detecting lymph node cancer spread, which is important for planning proper treatment.
Who this helps: This helps doctors determine the best imaging method for assessing lymph node involvement in breast cancer patients.
Plain English Schistosomiasis is a parasitic worm infection that damages the liver by leaving eggs in blood vessels, which eventually causes scarring and cirrhosis. The two main types of this infection show different patterns on medical imaging: one creates thick bands around the central liver blood vessels, while the other creates a distinctive "turtle-back" pattern of scarring in the outer liver with calcified eggs.
This infection commonly leads to serious complications like an enlarged liver and spleen, liver failure, high blood pressure in the liver's blood vessels, and bleeding from enlarged veins in the stomach and throat.
Dynamic CT for detecting small hepatocellular carcinoma: usefulness of delayed phase imaging.
2007
AJR. American journal of roentgenology
Monzawa S, Ichikawa T, Nakajima H, Kitanaka Y, Omata K +1 more
Plain English This study looked at how well a specific type of CT scan called dynamic CT can find small liver tumors (hepatocellular carcinomas or HCCs) in patients with liver cirrhosis. The researchers found that using all three phases of imaging—arterial, portal venous, and delayed—was most effective, detecting 93.8% of the small tumors compared to lower detection rates with fewer phases. This is important because early detection of these tumors can lead to better treatment outcomes for patients.
Who this helps: This benefits patients with liver cirrhosis by improving early diagnosis of liver tumors.
Acute tumor lysis syndrome caused by transcatheter oily chemoembolization in a patient with a large hepatocellular carcinoma.
2007
Cardiovascular and interventional radiology
Sakamoto N, Monzawa S, Nagano H, Nishizaki H, Arai Y +1 more
Plain English This study looks at a patient with a large liver cancer, known as hepatocellular carcinoma, who underwent a specific cancer treatment called transcatheter oily chemoembolization. After the treatment, the patient experienced a severe condition called acute tumor lysis syndrome, leading to metabolic changes and kidney failure, and ultimately resulted in the patient's death. This case highlights the importance of being aware of this serious risk when planning similar treatments for large liver tumors.
Who this helps: This information benefits doctors and medical professionals treating patients with liver cancer.
Hypointensity on postcontrast MR imaging from compression of the sacral promontory in enlarged uterus with huge leiomyoma and adenomyosis.
2007
Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine
Uotani K, Monzawa S, Adachi S, Takemori M, Kaji Y +1 more
Plain English This study looked at patients with large fibroids (leiomyomas) and adenomyosis, both of which are conditions affecting the uterus. Researchers found unusual dark areas on MR imaging of the uterus after contrast was applied in some of these patients, specifically near the sacral promontory, which is a part of the spine. Of the 12 patients studied, five had specific patterns of these dark areas that were linked to their conditions, but further tests showed no distinct problems in those areas, indicating the changes might be due to reduced blood flow from pressure.
Who this helps: This helps patients with large fibroids or adenomyosis and their doctors by improving understanding of imaging findings related to their conditions.
Portal venous tumor thrombus associated with hepatic metastasis of renal cell carcinoma: case report.
2006
Abdominal imaging
Sakamoto N, Monzawa S, Miyake M, Watanabe H, Hamanaka A +6 more
Plain English This study discusses a patient with kidney cancer that spread to the liver, forming a blood clot in a vein connected to the liver. Scans revealed a large tumor in the liver and several smaller growths in the blood vessels nearby, all linked to the main tumor. Understanding this condition is important because it highlights how kidney cancer can worsen by affecting the liver and blood flow, impacting treatment options.
Who this helps: This helps doctors and patients with kidney cancer by providing insights into severe complications of the disease.
High resolution CT findings of pulmonary epithelioid hemangioendothelioma: unusual manifestations in 2 cases.
2005
Journal of thoracic imaging
Sakamoto N, Adachi S, Monzawa S, Hamanaka A, Takada Y +3 more
Plain English This study looked at two unusual cases of a rare lung tumor called pulmonary epithelioid hemangioendothelioma (PEH), which mostly affects young women. In one case, a 54-year-old woman had multiple lung nodules with abnormalities in the surrounding tissue, while an 18-year-old woman displayed many tiny lung nodules. Both women also had liver issues, showing how this tumor can spread and appear in different ways, which can help doctors identify and treat this rare disease more effectively.
Who this helps: Patients with pulmonary epithelioid hemangioendothelioma and their doctors.
Performance assessment of phased-array coil in breast MR imaging.
2004
Magnetic resonance in medical sciences : MRMS : an official journal of Japan Society of Magnetic Resonance in Medicine
Ikeda T, Monzawa S, Komoto K, Aso E, Saito Y +3 more
Plain English This study looked at two types of coils—phased-array coil (PAC) and single-loop coil (SLC)—used in breast MRI to see which one produced better image quality. While the results showed that the SLC had a signal-to-noise ratio 1.82 times higher than the PAC, meaning clearer images in the center, the images from the PAC had better uniformity of fat saturation, which helps reduce image artifacts. The findings matter because better imaging can lead to more accurate diagnoses and better patient care, despite the PAC showing more noise in many cases.
Who this helps: This helps patients undergoing breast MRI by improving diagnostic accuracy and image quality.
Adachi S, Kono M, Takada Y, Ohbayashi K, Monzawa S +7 more
Plain English This research focuses on recent improvements in imaging methods for diagnosing lung cancer, specifically highlighting new technologies like multidetector-row CT (MDCT) and low-dose screening with MDCT. The study confirms that MDCT is very valuable for lung cancer diagnosis and suggests that combining it with PET scans, which provide additional metabolic information, enhances diagnosis. These advancements in imaging techniques could lead to better and earlier detection of lung cancer, improving patient outcomes.
Who this helps: This helps patients and doctors by providing better diagnostic tools for lung cancer.
A case with primary amyloidosis of the liver and spleen: radiologic findings.
2002
European journal of radiology
Monzawa S, Tsukamoto T, Omata K, Hosoda K, Araki T +1 more
Plain English This study focuses on a patient with primary amyloidosis affecting the liver and spleen, using imaging tests to identify the condition. The scans revealed unusual patterns: the liver showed uneven textures and slow enhancement, while the spleen lacked typical enhancement features. These specific findings help doctors recognize amyloidosis more accurately, which is important for timely treatment.
Who this helps: This helps patients with amyloidosis and their doctors.
Monzawa S, Omata K, Nakazima H, Yokosuka N, Ito A +1 more
Plain English This study examined how advanced gastric cancer appears on delayed phase dynamic CT scans in 43 patients. Researchers found that 57% of the tumors showed a specific pattern called delayed enhancement, which indicates abnormal changes in the gastric wall compared to healthy tissue. This finding is important because it can help doctors better identify and categorize advanced gastric cancer, improving diagnosis and treatment options.
Who this helps: This helps doctors and patients with advanced gastric cancer.
Well-differentiated hepatocellular carcinoma: findings of US, CT, and MR imaging.
1999
Abdominal imaging
Monzawa S, Omata K, Shimazu N, Yagawa A, Hosoda K +1 more
Plain English This study looked at how well different imaging tests—ultrasound, CT scans, and MRIs—could identify well-differentiated hepatocellular carcinoma (HCC), a type of liver cancer, in patients. Researchers examined images from 18 tumors found in 15 patients and found that many tumors were often difficult to see: only 4 out of 18 were detected on precontrast CT scans, and on MRIs, up to 11 tumors were not visualized at all. This matters because it shows that diagnosing this type of liver cancer using these imaging techniques can be challenging, which may lead to missed or delayed treatment.
Who this helps: Patients with liver cancer.
Curvilinear areas in the perinephric fat seen on MR images.
1999
Clinical radiology
Monzawa S, Schnall MD, Lee RC
Plain English This study looked at specific shapes in the fat around the kidneys (called strands and haloes) using MRI scans from 142 patients, including those with and without kidney disease. Researchers found that while these shapes are common and usually symmetrical, in 11 patients with kidney problems, they showed significant differences between sides, which may indicate deeper issues. Understanding these shapes can help doctors assess kidney health better, especially when they appear uneven.
Who this helps: This research benefits doctors and patients with kidney disease by improving diagnostic accuracy.
Shimazu N, Oba H, Aoki S, Monzawa S, Makita K +1 more
Plain English This study looked at whether the pituitary gland gets bigger in women with spontaneous intracranial hypotension (SIH), a condition causing severe headaches that improve when lying down. Researchers found that the pituitary gland was enlarged in all six patients, with heights between 8 to 11 mm, which is larger than typical sizes for women. This matters because it shows that SIH can physically affect the pituitary gland, helping doctors better understand the condition and its impact on patients' health.
Who this helps: This helps patients with spontaneous intracranial hypotension and their doctors.
Decreased signal intensity of cerebral cortex on T2-weighted MR images.
1996
Radiation medicine
Oba H, Ohtomo K, Araki T, Uchiyama G, Monzawa S +5 more
Plain English This study looked at brain imaging from 906 patients to see how often certain areas of the brain showed decreased signal intensity, which can indicate problems. They found that the frequency of this decreased intensity increased with age: for example, in the occipital lobe, 47.2% of patients showed this issue, while only 1.1% were found in the temporal lobe. This is important because it helps doctors understand how aging and white matter issues are related to brain health.
Who this helps: This information benefits doctors and neurologists monitoring brain health in older patients.
Septa in the liver of patients with chronic hepatic schistosomiasis japonica: MR appearance.
1994
AJR. American journal of roentgenology
Monzawa S, Ohtomo K, Oba H, Nogata Y, Kachi K +1 more
Plain English This study looked at the appearance of fibrous structures (called septa) in the livers of patients with chronic schistosomiasis japonica, using MRI images. Researchers reviewed MR images from 18 patients and found that these septa showed different signal intensities—low on some T1-weighted images but high on T2-weighted images—with 14 out of 18 patients showing these septa in at least one imaging sequence. Understanding how these septa appear on MRIs can help doctors better identify schistosomiasis and distinguish it from other liver diseases.
Who this helps: This helps doctors identify and treat patients with liver issues related to schistosomiasis.
Adrenal adenomas: characteristic hyperintense rim sign on fat-saturated spin-echo MR images.
1994
Radiology
Ichikawa T, Ohtomo K, Uchiyama G, Koizumi K, Monzawa S +5 more
Plain English This study focused on how to tell the difference between adrenal adenomas (benign tumors) and metastatic tumors (cancer spread) using a special type of MRI scan. Researchers found that 26 out of 28 adrenal adenomas showed a distinct feature called the hyperintense rim sign, while only 1 out of 20 metastatic tumors displayed this feature. This means the technique was very accurate, with a 92% sensitivity and 95% specificity, making it a reliable way to identify adrenal adenomas.
Who this helps: This benefits doctors and radiologists who need to accurately diagnose adrenal tumors.
[Evaluation of malignancy and viability of brain tumors by 201Tl SPECT: the correlation between 201Tl SPECT and pathology, clinical progress and the intensity of enhancement on CT images].
Ohnishi H, Koizumi K, Uchiyama G, Yamaguchi M, Okada J +5 more
Plain English This study looked at a special imaging method called Thallium-201 SPECT to check how effective it is at identifying aggressive brain tumors and figuring out if they are still active after treatment. Researchers evaluated 26 patients and found that high-grade tumors didn't always show high levels of Thallium uptake, while low-grade tumors, like pituitary adenomas, could appear similarly to aggressive tumors on scans despite being less concerning. This matters because it can help doctors better determine which tumors are truly dangerous and how to treat them, with accuracy rates for predicting tumor recurrence after radiotherapy being as high as 93.8%.
Who this helps: This helps doctors by improving their ability to assess brain tumors and make better treatment decisions.
[Radiation stenosis and fistula formation developed after iridium-192 high-dose-rate intracavitary radiation boost therapy for carcinoma of the esophagus].
Onishi H, Ogata H, Uchiyama G, Yamaguchi M, Toyama K +5 more
Plain English This study looked at a treatment called intracavitary radiation therapy for patients with advanced esophageal cancer. Out of 14 patients, 43% had their tumors completely disappear, but 36% developed serious complications like fistulas (abnormal connections between organs) and severe narrowing of the esophagus due to radiation damage. The findings suggest that a lower total radiation dose, below 120 TDF, could be safer and more effective for treating this type of cancer.
Who this helps: This helps patients with esophageal cancer by identifying safer treatment options.
Schistosomiasis japonica of the liver: contrast-enhanced CT findings in 113 patients.
1993
AJR. American journal of roentgenology
Monzawa S, Uchiyama G, Ohtomo K, Araki T
Plain English This study looked at the results of advanced CT scans in 113 patients diagnosed with liver schistosomiasis, a parasitic infection. Researchers found that nearly half of the patients (48%) showed signs of liver enhancement after contrast was added, which can indicate the disease. Notably, 46% of patients had specific patterns of enhancement related to scarring in the liver. These findings are significant as they can help doctors identify and diagnose liver schistosomiasis more accurately, especially when earlier scans don't show calcification.
Who this helps: This benefits patients and doctors by improving diagnosis and treatment options for schistosomiasis.
Amyotrophic lateral sclerosis: T2 shortening in motor cortex at MR imaging.
1993
Radiology
Oba H, Araki T, Ohtomo K, Monzawa S, Uchiyama G +5 more
Plain English This study looked at brain images from 15 patients suspected of having amyotrophic lateral sclerosis (ALS) and compared them to images from 49 healthy individuals. The researchers found that 14 out of the 15 patients showed a specific change in their brain images (T2 shortening) that was not present in the healthy group. This change may be related to nerve damage and can help doctors diagnose ALS more accurately.
Who this helps: Patients with ALS and their doctors.
MR imaging of malignant mesenchymal tumors of the liver.
1992
Gastrointestinal radiology
Ohtomo K, Araki T, Itai Y, Monzawa S, Ohba H +4 more
Plain English This study looked at five rare types of liver tumors and how they appear on magnetic resonance imaging (MRI). The researchers found that all the tumors showed specific patterns on the MRI scans, such as being dark on one type of image and bright on another, but it was hard to tell them apart from other liver tumors. This information is important because it highlights the challenges doctors face in accurately diagnosing these unusual tumors using MRI alone.
Who this helps: This helps doctors and medical professionals who treat patients with liver tumors.
Oba H, Araki T, Monzawa S, Onishi H, Toyama K +5 more
Plain English This study looked at brain scans using magnetic resonance imaging (MRI) to understand iron buildup in people with amyotrophic lateral sclerosis (ALS), a serious nerve disease. Researchers examined 8 ALS patients and found that all of them had lower signals in the part of the brain that controls movement, compared to just one out of 49 healthy individuals. This finding is important because it may help in identifying brain changes linked to ALS, potentially leading to better diagnosis or treatment options.
Who this helps: This benefits patients with ALS and their doctors.
Dense parenchymal accumulation of Lipiodol after transarterial chemoembolization.
1992
Radiation medicine
Hihara T, Araki T, Kachi K, Monzawa S, Uchiyama G
Plain English This study looked at how a substance called Lipiodol, used during a liver cancer treatment called transarterial chemoembolization (TACE), accumulated in liver tissue. Out of six patients, all showed a noticeable build-up of Lipiodol two weeks post-treatment, with four of them having levels comparable to tumor areas by three weeks. This is important because it indicates that doctors need to wait at least a month after TACE to accurately assess where the Lipiodol is accumulating, which helps distinguish between cancerous and normal liver tissue.
Who this helps: This helps doctors accurately monitor liver cancer treatment in their patients.
Magnetic resonance imaging of macroscopic intrahepatic portal-hepatic venous shunts.
1991
Gastrointestinal radiology
Araki T, Ohtomo K, Kachi K, Monzawa S, Hihara T +4 more
Plain English This study looked at a rare condition where blood vessels in the liver are connected in an unusual way, known as intrahepatic portal-hepatic venous shunts. Researchers examined five patients using MRI and found different types of shunts; one patient had multiple shunts while the others had a single irregularly shaped shunt. Understanding this condition is important because it can affect how the liver functions and help guide treatment for patients.
Who this helps: This helps patients with liver conditions and their doctors.
Plain English This study looked at the brain images of five patients with a rare condition called membranous lipodystrophy, which involves memory loss and other symptoms. The brain scans revealed that these patients had shrinking white matter and enlarged brain ventricles, along with specific changes in various brain structures. These findings are important because they, when combined with certain bone issues, help identify this rare disease more accurately.
Who this helps: This information helps doctors diagnose and treat patients with membranous lipodystrophy more effectively.
Koizumi K, Uchiyama G, Araki T, Hihara T, Ogata H +5 more
Plain English This study assessed a new bone density measurement device called the Hologic QDR-1000, which uses a method called DEXA. The researchers found that it gives good quality images and has minimal radiation exposure, with bone density measurements being fairly reliable and accurate. It's important because it provides a way to measure bone health effectively, which can help in diagnosing conditions like osteoporosis.
Who this helps: This helps patients at risk of bone diseases and their doctors.
Visualization of the bone/bone marrow of lower extremities in Ga-67 whole-body images.
1990
Annals of nuclear medicine
Koizumi K, Uchiyama G, Araki T, Hihara T, Ogata H +5 more
Plain English This study looked at how images from a specific scan (Ga-67 whole-body images) showed changes in the bones and bone marrow of the lower legs in patients. Out of 374 scans, 59 (15.8%) showed increased activity in the bones, which researchers grouped into three types based on how clear the images were. They found that patients with the most intense images (type T) had high iron levels, while those with weaker images (type S) had low iron levels, indicating that the way the bones appeared in the scans is related to how the body uses iron.
Who this helps: This benefits patients with iron metabolism issues and their doctors by providing insights into their conditions.
67Ga scan for evaluating response to therapy in malignant lymphoma.
1989
European journal of nuclear medicine
Koizumi K, Ogata H, Uchiyama G, Araki T, Hihara T +3 more
Plain English This study looked at how a specific imaging test, the 67Ga scan, can show the effectiveness of chemotherapy in patients with malignant lymphoma. The researchers found that the scan did not pick up on some active cancer cells within a largely dead tumor mass, meaning that just because the scan shows no signs of cancer doesn't mean there aren't any living cells left. This finding is important because it suggests that relying solely on this scan might lead to an incomplete understanding of a patient's treatment response.
Who this helps: This helps doctors better assess treatment effectiveness in lymphoma patients.
Computed tomographic detection of intestinal calcification of Schistosomiasis japonica.
1989
Gastrointestinal radiology
Araki T, Kachi K, Monzawa S, Matsusako M, Hihara T +1 more
Plain English This study looked at four patients with Schistosomiasis japonica, a parasitic infection, and found that they all had deposits of calcium in their intestines, which can be seen using a special imaging technique called a CT scan. Specifically, one patient had calcification in the upper part of the small intestine (duodenum), while the other three had it in the rectum and/or colon. This information is important because it can help doctors recognize and diagnose this infection more effectively, leading to better treatment for affected patients.
Who this helps: This helps patients with Schistosomiasis japonica and their doctors in diagnosing the infection.
[Detectability of metastatic bone tumor by Ga-67 scintigraphy].
1989
Kaku igaku. The Japanese journal of nuclear medicine
Koizumi K, Uchiyama G, Araki T, Hihara T, Ogata H +3 more
Plain English This study looked at how well a specific imaging technique, Ga-67 scintigraphy, can detect bone tumors that have spread from other parts of the body (metastatic bone tumors) compared to another imaging method, Tc-99m bone scintigraphy. The researchers found that out of 47 metastatic lesions, 23 (49%) showed clear signs of the tracer uptake, while 17 (36%) showed no uptake at all. In contrast, only 7 out of 71 benign bone lesions (10%) showed clear uptake, mostly related to fractures. The findings indicate that Ga-67 scintigraphy misses many bone metastases, especially in patients with multiple tumors, which raises concerns about its reliability for detecting these serious conditions.
Who this helps: This research helps doctors better understand which imaging techniques to use for diagnosing bone tumors in patients.
[Ga-67 scintigraphy for the localization and staging of malignant lymphoma].
1988
Gan no rinsho. Japan journal of cancer clinics
Monzawa S, Karikomi M, Uno K, Itami J, Arimizu N
Plain English In this study, researchers looked at 38 imaging scans using a radioactive substance called Ga-67 in patients with untreated or recurring malignant lymphoma. They found that 89% of the scans showed signs of the disease, with involvement of Waldeyer's ring and lymph nodes occurring in two-thirds of the cases. This is important because it helps doctors identify where the cancer is and how severe it is, improving treatment decisions, especially for those facing recurrence.
Who this helps: This helps doctors and patients managing malignant lymphoma.