Dr. S Pitoni studies how to optimize breathing support for patients who have suffered brain injuries and are also affected by ARDS, a condition that makes it difficult for patients to breathe. They specifically investigate the effects of different breathing devices and techniques to ensure that these vulnerable patients receive the best care possible. Their research examines how using a heated humidifier can allow for better control of the amount of air delivered to these patients while maintaining brain safety.
Key findings
Switching from a heat and moisture exchanger (HME) to a heated humidifier (HH) allowed for a tidal volume reduction of 120 ml in brain-injured ARDS patients.
The implementation of the HH improved management of breathing pressure without compromising blood flow to the brain.
Using HH as a ventilation method has the potential to lead to better patient outcomes in brain-injured individuals with ARDS.
Frequently asked questions
Does Dr. Pitoni study brain injury?
Yes, Dr. Pitoni's research specifically focuses on patients with brain injuries.
What treatments has Dr. Pitoni researched for ARDS?
Dr. Pitoni has researched the effectiveness of different breathing devices, particularly heated humidifiers, in treating ARDS.
Is Dr. Pitoni's work relevant to patients with brain injuries and ARDS?
Absolutely, their work is dedicated to improving care for this patient group.
Publications in plain English
Continuous versus intermittent noninvasive blood pressure monitoring during beach chair position for shoulder surgery: A randomised controlled trial.
2026
European journal of anaesthesiology
Vergari A, Frassanito L, Piersanti A, Vassalli F, Pitoni S +8 more
Plain English This study looked at two methods of monitoring blood pressure during shoulder surgery when patients are in a sitting position. Researchers found that continuous monitoring using a finger cuff did not significantly reduce low blood pressure episodes compared to standard monitoring techniques. Specifically, the average time-weighted blood pressure below a critical level was slightly lower in the continuous group (0.41 mmHg) than in the standard group (0.69 mmHg), but the difference wasn't large enough to be considered significant.
Who this helps: This benefits doctors performing shoulder surgeries by clarifying the effectiveness of different blood pressure monitoring methods.
Tidal Volume Lowering by Instrumental Dead Space Reduction in Brain-Injured ARDS Patients: Effects on Respiratory Mechanics, Gas Exchange, and Cerebral Hemodynamics.
Plain English This study looked at how switching from a heat and moisture exchanger (HME) to a heated humidifier (HH) could help lower the amount of air (tidal volume) given to brain-injured patients with acute respiratory distress syndrome (ARDS). Researchers found that using the HH allowed a reduction in tidal volume by 120 ml and helped improve the management of breathing pressure without harming blood flow to the brain. This matters because it shows a safer way to ventilate patients with both brain injuries and ARDS, potentially leading to better outcomes.
Who this helps: This helps brain-injured patients suffering from ARDS and their doctors.
Statistical methodology for the evaluation of leukocyte data in wild reptile populations: A case study with the common wall lizard (Podarcis muralis).
2020
PloS one
Sacchi R, Mangiacotti M, Scali S, Coladonato AJ, Pitoni S +2 more
Plain English This study looked at the immune system of the common wall lizard, analyzing blood samples from 794 lizards across 54 populations in Italy to better measure their health and stress levels. It found that factors like the lizard’s size, sex, latitude, and the time of year significantly affect their white blood cell profiles, showing that these profiles can vary greatly between different lizard populations. Understanding these variations is important for accurately assessing the health of wild reptiles, as it challenges previous assumptions made from studies on captive animals.
Who this helps: This helps researchers and conservationists working to protect wild reptile populations.
Lung ultrasound to monitor the development of pulmonary atelectasis in gynecologic oncologic surgery.
2020
Minerva anestesiologica
Frassanito L, Sonnino C, Pitoni S, Zanfini BA, Catarci S +5 more
Plain English This study looked at how lung ultrasound can be used to track changes in lung function during gynecologic oncologic surgery. The researchers found that lung aeration decreased significantly after the surgery, with average ultrasound scores going from about 1.8 to 11.1, indicating more severe lung collapse. This matters because understanding how surgical factors affect lung health can help improve patient care after surgery.
Who this helps: Patients undergoing gynecologic oncologic surgery.
Ultrasound-guided genitofemoral nerve block for inguinal hernia repair in the male adult: a randomized controlled pilot study.
2018
Minerva anestesiologica
Frassanito L, Zanfini BA, Pitoni S, Germini P, Del Vicario M +1 more
Plain English This study looked at whether adding a genitofemoral nerve block to a common anesthesia technique for inguinal hernia surgery can reduce pain and improve anesthesia. Researchers found that patients who received both nerve blocks had significantly lower pain scores and needed less extra anesthesia during the surgery. Specifically, they used an average of 13.8 mL of additional anesthesia compared to 20.7 mL for those who only had one block, which is an important difference for better pain management.
Who this helps: This benefits male patients undergoing inguinal hernia repair by reducing their pain and the need for extra sedation.
Utility of ultrasound-guided transversus abdominis plane block for day-case inguinal hernia repair.
2017
Korean journal of anesthesiology
Frassanito L, Pitoni S, Gonnella G, Alfieri S, Del Vicario M +2 more
Plain English This study examined how well a specific pain relief method, called the TAP block, works when combined with another anesthesia technique during outpatient inguinal hernia surgeries. Researchers found that only 12.5% of patients using the TAP block had inadequate anesthesia, compared to 37% of those who did not use it. Additionally, patients who received the TAP block reported significantly lower pain levels throughout their recovery, especially right after surgery and up to 24 hours later.
Who this helps: This benefits patients undergoing outpatient inguinal hernia repairs by reducing their pain and improving their comfort.
Ultrasound-guided "short" midline catheters for difficult venous access in the emergency department: a retrospective analysis.
2016
International journal of emergency medicine
Scoppettuolo G, Pittiruti M, Pitoni S, Dolcetti L, Emoli A +3 more
Plain English This study looked at using longer catheters guided by ultrasound to help emergency department patients who have difficult-to-access veins. Out of 76 patients, the insertion success rate was 100%, taking an average of about 9 and a half minutes, and 73% of these catheters functioned well for over a week without major complications. This finding is important because it shows that these longer catheters can provide better and longer-lasting access to veins in patients with challenging conditions.
Who this helps: Patients in emergency situations needing quick vascular access.
Echography in brain imaging in intensive care unit: State of the art.
2014
World journal of radiology
Caricato A, Pitoni S, Montini L, Bocci MG, Annetta P +1 more
Plain English This study looked at a brain imaging technique called transcranial sonography (TCS), which uses ultrasound to visualize different parts of the brain. The findings show that TCS can effectively diagnose various brain issues, like bleeding and swelling, in adult patients at the bedside, and it is faster and cheaper than traditional imaging methods like CT scans or MRIs. This is important because it allows for quick and continuous monitoring of patients, especially in emergency situations.
Who this helps: This benefits patients in intensive care units by providing faster and safer brain assessments.
Racemic ketamine in adult head injury patients: use in endotracheal suctioning.
2013
Critical care (London, England)
Caricato A, Tersali A, Pitoni S, De Waure C, Sandroni C +4 more
Plain English This study looked at the effects of using ketamine on patients with head injuries during a procedure called endotracheal suctioning (ETS) in the ICU. The researchers found that while ETS increased pressure in the skull in patients receiving regular sedation, those who were given ketamine showed less coughing and maintained stable blood flow and oxygen levels in the brain, but still experienced an increase in pressure. Importantly, ketamine didn't completely prevent the rise in skull pressure, but it helped manage other vital signs during the procedure.
Who this helps: This benefits patients with head injuries undergoing respiratory care in the ICU.
Plain English This research paper looks at how the body regulates temperature and its importance for using controlled cooling as a treatment for conditions like traumatic brain injury and stroke. The findings highlight that preventing shivering during therapeutic hypothermia is crucial, as it may help protect the brain more effectively. Although various drugs have been tested to stop shivering, the best approach is still unclear, and further clinical trials are needed to find the most effective treatment protocols.
Who this helps: This helps patients recovering from brain injuries and strokes.
Anaesthesia for total knee arthroplasty: efficacy of single-injection or continuous lumbar plexus associated with sciatic nerve blocks--a randomized controlled study.
2009
European review for medical and pharmacological sciences
Frassanito L, Vergari A, Messina A, Pitoni S, Puglisi C +1 more
Plain English This study looked at two different methods of managing pain after total knee surgery: one-time injections versus continuous infusion of anesthesia. Researchers found that while patients in the continuous infusion group used slightly less tramadol pain relief (about 5% less), the difference was not significant. Both methods were effective and led to high satisfaction among patients, which is important for their recovery after surgery.
Who this helps: This benefits patients undergoing knee surgery.