Shadi Rahimi

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This study looked at how different factors affect the reference values used to assess blood flow in the umbilical artery during pregnancy. Researchers analyzed over 25,000 measurements from nearly 12,400 pregnancies and found that using different weight categories for babies led to varied results; for example, when using charts based on higher weight cut-offs, the percentage of tests showing high pulsatility (which can indicate issues) increased significantly (11.5% and 13.2% compared to 10.6%, with a clear statistical difference). Understanding this variation is important because it affects how safely and effectively doctors monitor pregnancies. Who this helps: This helps doctors provide better care for pregnant women and their babies.

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This research examined how non-coding RNAs, particularly microRNAs, affect the ability of glioma cancer cells to respond to Carmustine, a key chemotherapy drug. The study reviewed 12 previous studies and found that changes in non-coding RNA levels can significantly alter how sensitive glioma tumors are to Carmustine. Understanding these interactions can help develop better treatments for glioma and overcome drug resistance. Who this helps: This benefits patients with glioma and their doctors.

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This study looked at how older fathers (aged 40 and above) may affect the DNA of their children through changes in the placenta. Researchers examined 64 placenta samples and found that older paternal age was linked to DNA changes in 688 genes, with about 65% showing reduced methylation, which is important for gene regulation. This is significant because some of these genes are known to be related to brain development and disorders like autism, suggesting that advanced paternal age could impact a child's neurological health. Who this helps: Patients and families concerned about the effects of older fathers on child development.

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This research focused on how a type of white blood cell called neutrophils contributes to the development and spread of ovarian cancer. The study found that neutrophils change their behavior and create structures called NETs that help the tumor grow by making it easier for cancer cells to spread and evade the immune system. By understanding this process, researchers believe they can find new ways to treat ovarian cancer that might make existing therapies more effective. Who this helps: This benefits ovarian cancer patients by providing potential new treatment options.

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This study looked at sand flies, which spread a disease called cutaneous leishmaniasis (CL), in Isfahan Province, Iran, from 2019 to 2023. Researchers collected over 17,000 sand flies and found that two types, Sergentomyia sintoni (48%) and Phlebotomus papatasi (30%), were the most common. Most sand flies were found outdoors, especially in June and August, highlighting the need for better control measures against these insects to protect public health. Who this helps: This information benefits patients at risk of cutaneous leishmaniasis and public health officials working to reduce the disease's spread.

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This study looked at how different climate data models predict when valley fever, a fungal infection known as coccidioidomycosis, will be most common as temperatures rise. It found that using one model, the disease's active season is expected to start 4.2 weeks earlier and end 4.1 weeks later than it does now, while another model projected it starting 4 weeks earlier and ending 3.8 weeks later. These changes matter because they show health risks from valley fever will increase over a longer period, which affects how communities can prepare for and respond to the disease. Who this helps: This helps patients and public health officials planning for changes in disease patterns.

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Researchers studied a new type of coating for medical implants designed to fight infections caused by superbugs that don't respond to traditional antibiotics. They developed a special coating that combines nanoparticles and vertical graphene, which significantly reduced the number of bacteria by 10,000 times, achieving 99.99% effectiveness against these germs, while still being safe for human cells. This is important because it offers a new way to prevent serious infections in patients with implants, which can often be difficult to treat. Who this helps: Patients receiving medical implants.

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This study focused on finding new ways to treat cervical cancer caused by high-risk human papillomavirus (HPV), particularly types 16 and 18, which are known to contribute to cancer development. Researchers discovered promising methods to target a specific viral protein called E7 that helps cancer cells grow, including therapies that use the body's immune system and advanced genetic technologies. These approaches aim to reactivate important cancer-fighting proteins and stop the cancer cells from dividing. Who this helps: This benefits women with cervical cancer and researchers developing new treatments.

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This study focused on creating a new type of catalyst made from iron, cobalt, and palladium to improve a chemical reaction called Suzuki–Miyaura coupling, which is important for making complex molecules. The researchers found that this catalyst was able to produce 78% of the desired product when used under mild conditions, and it can be easily recovered and reused due to its magnetic properties. This matters because it makes this chemical process more efficient and sustainable, potentially reducing waste and cost. Who this helps: This benefits researchers and industries involved in chemical manufacturing, especially those working on pharmaceuticals and materials.

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This study looks at medulloblastoma, a common type of brain cancer in children, particularly focusing on a subgroup influenced by the Sonic Hedgehog (SHH) pathway. Researchers examined the drug vismodegib, which blocks this pathway, and found it can improve survival without the cancer progressing, but it can also cause harmful side effects like bone problems in kids. By exploring new ways to deliver the drug or combining it with other treatments, there's potential to make it safer and more effective for young patients. Who this helps: This research benefits children with medulloblastoma and their doctors.

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This research focuses on improving treatment for cervical cancer using new hydrogel materials in a type of radiation therapy called brachytherapy. The study found that using hydrogels can lead to better tumor control and reduce damage to nearby healthy tissues, making treatments safer and more effective. For instance, early findings indicate that these hydrogels can improve how well tumors respond to treatment and lower side effects from radiation. Who this helps: This benefits cervical cancer patients by providing safer and more effective treatment options.

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This study looked at an outbreak of dengue fever (DF) in Bandar Abbas, Iran, from August to October 2025, finding 56 cases, mostly among construction workers. Most infected people were men around 36 years old, with common symptoms like headaches and body pains. Fortunately, everyone recovered, highlighting the need for better detection and control measures to prevent further spread, especially since this city is an important trade center. Who this helps: This information benefits public health officials and local communities at risk of dengue fever.

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This study looked at how adding L-carnitine and L-arginine to the diets of older roosters affects their reproductive health. Researchers found that the roosters who received L-carnitine had improved testicular development, with significant increases in the size of important tissue structures and better reproductive hormones, leading to higher fertility and hatch rates. For example, the fertility and hatchability rates were significantly better in the roosters fed with L-carnitine compared to the control group. Who this helps: This research benefits poultry farmers and breeders looking to enhance the reproductive performance of their roosters.

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This study looked at a new method called the Residual Graph Attention Network (R-GAT) to classify cancer-related research abstracts. The researchers tested it on 1,875 abstracts and found that R-GAT performed very well, achieving a score of 0.96 on a key measurement of accuracy, while using less computing power than other complex models. This matters because it offers a more efficient way to analyze cancer research data, making it easier to categorize important information even when there isn’t a lot of available data. Who this helps: This helps researchers and healthcare professionals working in cancer informatics.

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This study looked at milk extracellular vesicles (MEVs), tiny particles found in milk that could be used to deliver medicines more effectively. Researchers found that these vesicles, which are about 30 to 150 nanometers in size, can carry drugs while being safe for the body and able to reach target areas, making them useful for treating cancers and other diseases. Their findings underscore the importance of developing better techniques to use MEVs for drug delivery, emphasizing a need for more research to confirm their safety and effectiveness in medical treatments. Who this helps: Patients needing innovative drug delivery methods for various health conditions.

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This study looked at whether virtual reality (VR) can help reduce pain in patients recovering from a heart procedure called percutaneous coronary intervention (PCI). Out of 144 participants, those who used VR experienced a significant decrease in pain levels compared to those who received routine care, showing better results (p < 0.01). This matters because it offers a safe, non-drug option for managing pain, which can improve recovery and quality of life for these patients. Who this helps: This benefits patients undergoing PCI by providing an effective way to manage their pain post-procedure.

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This study looked at lead-free halide perovskites, which are materials that could be used in electronics that don't harm the environment. The researchers found that the arrangement of certain electrons in these materials, specifically the "lone pairs" of electrons, plays a key role in their stability and how well they absorb light. They discovered that adjusting these materials by partially replacing one element with another could improve their performance without losing their light-absorbing qualities, showing that managing these electron arrangements can help create better, eco-friendly materials for various applications. Who this helps: This benefits researchers and manufacturers working on sustainable electronics.

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This study looked at a new way to handle bacterial infections that are resistant to antibiotics. Researchers tested a special molecule called BzLPRDSar, which blocks a bacterial enzyme that helps harmful bacteria stick to surfaces and form protective layers. They found that BzLPRDSar effectively stopped biofilm formation in drug-resistant strains of Staphylococcus, but it worked less well on other types of bacteria, indicating that different bacteria have varying enzyme structures. Who this helps: This impacts patients with antibiotic-resistant infections, as it offers a new treatment strategy that could be safer and more effective.

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This study focused on creating a questionnaire to measure children's fears and behaviors related to insects in East Azerbaijan, Iran. Researchers tested the questionnaire on 1,370 school-aged children and found it effectively assesses knowledge, fear, behaviors, and anxiety about insects, with strong reliability and validity scores. This tool is important because it can help identify children with high levels of fear or unsafe practices around pesticides, contributing to their overall well-being and safety. Who this helps: This helps children, parents, and educators.

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This study looked at how linalool, a natural compound found in many plants, can protect male reproductive health in rats exposed to a toxic chemical called carbon tetrachloride. The researchers found that linalool improved markers of oxidative stress and reduced damage in the testicular tissue, with significant improvements in antioxidant levels and decreases in harmful substances after linalool treatment (with one key finding showing a decrease in malondialdehyde levels). These results are important because they suggest that linalool may be a useful treatment option for protecting against male infertility linked to oxidative stress. Who this helps: This helps men facing infertility issues, as well as doctors looking for alternative treatments.

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This study looked at how effective cognitive-behavioral therapy (CBT) is for teenagers with impulsive aggressive behavior, specifically those diagnosed with intermittent explosive disorder (IED). Researchers found that after 12 weeks of CBT, the 21 teens in the therapy group showed significant improvements, including a 50% reduction in aggressive behavior and better control over their emotions and impulses compared to the 21 teens on a waiting list. This matters because it shows that CBT can effectively help teens manage their aggression and improve their overall functioning. Who this helps: This helps adolescents struggling with aggressive behaviors and their families.

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This study looked at the role of a protein called ATF6 in a type of leukemia known as B-cell precursor acute lymphoblastic leukemia (BCP-ALL) in children. The researchers found that children with relapsed leukemia had higher levels of ATF6, and when they blocked this protein using a specific drug, it increased the cancer cells' sensitivity to a common chemotherapy drug called doxorubicin. This is significant because it shows a potential new way to improve treatment outcomes for children with this aggressive form of leukemia. Who this helps: This helps pediatric leukemia patients by potentially enhancing their treatment effectiveness.

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This study examined how silver nanoparticles made using natural materials can fight bacteria that cause dental cavities, which are hard to treat due to their tough biofilm structures. The researchers found that these green-synthesized silver nanoparticles significantly reduced bacterial growth and weakened the biofilm, showing a notable decrease in bacterial mass and structure. Specifically, they caused changes in bacterial genetics that disrupted their metabolism and ability to survive, making them an eco-friendly option for preventing cavities and managing biofilms. Who this helps: This research benefits dentists and their patients by providing a new way to treat and prevent dental infections.

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This study looked at how likely pregnant women are to use a mobile app to help them make decisions about prenatal screening for genetic conditions like Down syndrome (trisomy 21), and others (trisomies 18 and 13). Out of 67 women surveyed, those who believed that the app would be helpful and who felt positive social pressure from others were more likely to want to use it, explaining nearly 78% of their intentions. The findings highlight the importance of promoting the benefits of mobile decision aids to help more women make informed choices during pregnancy. Who this helps: This helps pregnant women by giving them better tools to make important health decisions.

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This study looked at how cough sounds can help detect COVID-19 among people in two different locations: Lima, Peru, and Montreal, Canada. Researchers analyzed cough recordings from 605 adults and found that models used to identify COVID-19 from cough sounds worked better in Lima (71% accuracy) than in Montreal (53% accuracy). This is important because it shows that cough characteristics vary by location, which affects how well these detection tools can be used globally. Who this helps: This helps researchers and healthcare providers develop better COVID-19 screening tools adapted for different populations.

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This study looked at how training using the WHO AWaRe Antibiotic Handbook affected the knowledge of private primary care providers (PCPs) in Patna, India, about prescribing antibiotics. After training 145 providers, the results showed a significant decrease in inappropriate antibiotic prescribing for conditions like acute diarrhea and urinary tract infections, with a drop in prescribing wrong antibiotics from around 60% to about 30% for those conditions. This is important because better antibiotic prescribing helps combat antibiotic resistance and improves patient care. Who this helps: Patients, especially those suffering from common infections like diarrhea and UTIs.

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This study examined how artificial intelligence (AI) is being used to identify frailty in patients, which is important for early intervention. Researchers reviewed 33 academic publications and found 23 different AI techniques being tested, with the most common ones being logistic regression and decision trees. However, there was no consistent definition of frailty across these studies, and user feedback was largely missing, which could affect how effective and equitable these tools are in practice. Who this helps: This helps doctors and healthcare providers who need better tools to identify frail patients early on.

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This study looked at how well N-acetylcysteine (NAC) protects the lungs of rats from damage caused by mercury exposure. It found that rats who received NAC after being exposed to mercury showed lower levels of toxic effects and reduced mercury levels in their blood and lungs. Specifically, the treated rats had significant reductions in harmful gene expressions and improved health compared to those not treated with NAC. This matters because it highlights a potential way to protect lung health in situations where people may be exposed to mercury. Who this helps: This benefits patients who may be exposed to mercury, such as those in certain occupational settings.

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This study looked at the treatment of chronic subdural hematoma (cSDH), a condition that often requires surgery. Researchers compared costs between patients receiving surgery alone and those also getting an additional treatment called middle meningeal artery (MMA) embolization. They found that surgery alone was cheaper, costing an average of $158,320 compared to $235,263 for surgery with embolization. However, the embolization could reduce future hospital visits and repeated surgeries, making it financially sensible in certain cases. Who this helps: This information benefits patients with cSDH by providing options for more effective and potentially cost-saving treatments.

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Researchers treated a 42-year-old man with facial pseudolymphoma that hadn't improved after many standard therapies, using a drug called intravenous rituximab. After four weeks of treatment, the man's skin lesions greatly improved and stayed away for at least a year. This finding is important because it shows that rituximab can be effective for this stubborn skin condition when other treatments fail. Who this helps: Patients with treatment-resistant pseudolymphoma.

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This study looked at how specific antibodies from egg yolks (IgY) can fight against Salmonella Typhimurium, a common cause of food poisoning linked to poultry. Researchers compared two ways to make these antibodies using different preparations of the bacteria and found that one method (ultrasonically prepared antigen) produced more effective antibodies. The results showed that these antibodies significantly reduced bacterial growth and prevented adherence to the gut, which is crucial for improving food safety and reducing the need for antibiotics in poultry farming. Who this helps: This helps poultry farmers and improves food safety for consumers.

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This study looked at how geraniol, a natural compound, can protect the liver from damage caused by a condition known as ischemia-reperfusion injury (HIRI), which often occurs during liver surgeries. The researchers found that geraniol reduced liver damage and improved liver function in rats, lowering liver enzyme levels significantly compared to untreated rats after injury. This is important because it suggests that geraniol could help prevent severe liver problems, like fibrosis, following surgeries. Who this helps: This helps patients undergoing liver surgery.

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Researchers studied how to effectively remove harmful endotoxins from antibodies used in treating autoimmune diseases like pemphigus vulgaris. They found that their new method reduced endotoxin levels by over 95% while also recovering 85% of the antibody, ensuring the treated antibodies meet safety standards. This is important because endotoxin contamination can compromise research results and patient safety. Who this helps: Patients and healthcare providers needing safe and effective antibody treatments.

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This study looked at how nonthrust joint mobilization techniques can help patients with adhesive capsulitis, also known as frozen shoulder. Researchers found that these techniques significantly reduced pain by an average of 1.19 points, improved functional disability scores by up to 10.11 points, and increased shoulder movement by about 17.71 degrees in flexion. This is important because it shows that nonthrust mobilization can effectively improve the quality of life for people suffering from this condition. Who this helps: This helps patients with adhesive capsulitis and their doctors.

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This research looked at how stem cell therapy affects liver fibrosis, a condition that leads to liver damage and failure. The review of 29 studies found that stem cells can reduce inflammation and fibrosis markers while promoting healing in the liver. For instance, they lowered certain harmful inflammation markers and increased beneficial anti-inflammatory substances. This is important because it shows that stem cell therapy could improve liver health and function, paving the way for better treatment options. Who this helps: This benefits patients with liver fibrosis and their doctors by providing new potential treatments.

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This study looked at how lavender extract, delivered using tiny fat particles, affects mouse sperm during freezing and thawing. The researchers found that using a low concentration (1.5 µg/mL) of this lavender extract improved sperm survival and movement, reduced damage to DNA, and boosted the activity of important antioxidant enzymes. These results indicate that lavender extract could help improve the preservation of sperm by reducing oxidative stress. Who this helps: This helps patients undergoing fertility treatments and researchers in reproductive health.

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This study looked at the connection between a specific genetic variant (NQO1 rs1800566), changes in a gene's expression (methylation), and the risk of preeclampsia in pregnant women. Researchers examined 170 women and found that those with preeclampsia had lower levels of some important antioxidants and minerals, but higher levels of oxidative stress markers, indicating a problem with their body’s ability to manage oxidative stress. However, the genetic variant and methylation changes didn't show any link to the increased risk of preeclampsia. Who this helps: This research helps doctors understand the biological factors in preeclampsia, which could lead to better management strategies for pregnant women at risk.

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This study focused on a protein called CREG1 and its role in heart health, especially under stress and aging. Researchers found that mice missing CREG1 developed heart problems, including thickening of the heart muscle and reduced ability to pump blood, as early as 80 weeks old, while those with extra CREG1 showed better heart function during stress. These findings highlight the importance of CREG1 in protecting the heart from damage due to poor nutrition and aging. Who this helps: This helps patients with heart conditions and aging individuals by identifying a potential target for therapies to improve heart health.

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This study looked at a special material called TiCO, focusing on its structure and how it interacts with light and electricity. Researchers found that TiCO has useful properties, like an energy gap that makes it effective for electronics, with specific measurements showing strong light absorption starting at 0.99 eV. This is important because TiCO could be used for devices like solar panels and sensors. Who this helps: This benefits engineers and scientists developing advanced electronic devices.

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This study looked at a 72-year-old woman suffering from erosive vulvovaginal lichen planus, a painful condition that causes inflammation and sores. After traditional treatments failed to help her vulvovaginal lesions, she received three monthly injections of platelet-rich fibrin (PRF), which completely healed the sores and provided significant relief from her symptoms. This approach is promising because it offers a minimally invasive option for patients who do not respond to standard treatments. Who this helps: Patients with erosive vulvovaginal lichen planus.

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The researchers studied how to make light-emitting diodes (LEDs) that emit near-infrared light work better by using special tiny structures called nanorods in their design. They found that by embedding these nanorods in a specific fluoride layer, the LEDs achieved an impressive optical efficiency of around 45%, which is 3 to 4 times better than traditional designs. This improvement matters because higher efficiency means these LEDs can use less energy and produce more light, benefiting various technologies that rely on infrared light. Who this helps: This helps patients who need advanced medical imaging or therapeutic devices that use infrared light.

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This study focused on a new method for treating melanoma, a type of skin cancer, using special scaffolds that slowly release a drug called indirubin. The researchers created these scaffolds with certain materials and found that they not only effectively released indirubin over about 72 hours but also reduced the survival of melanoma cells significantly. Specifically, the scaffold decreased cell viability and triggered the death of cancer cells, showing strong potential for localized melanoma treatment. Who this helps: This benefits patients with melanoma and healthcare providers looking for targeted treatment options.

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This study looked at the relationship between mobile phone use and breast cancer risk in women from Iran. It found that women who talked on their phones for more than an hour each day were nearly 3.5 times more likely to have confirmed breast cancer, and over 10 times more likely to be suspected cases, compared to those who used their phones for less than 10 minutes daily. This research is important because it raises concerns about how long-term exposure to mobile phone radiation may affect women's health. Who this helps: Women concerned about breast cancer and healthcare providers assessing risk factors.

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This study looked at how methamphetamine affects the growth and development of blowfly larvae, which are used in forensic science to help determine how long a body has been dead. The researchers found that higher levels of methamphetamine (90 and 180 ng/mg) shortened the larvae's development time by 24 hours and caused them to grow smaller and lighter compared to a control group. This is important because not recognizing methamphetamine's presence could lead to incorrect estimates of how long a person has been deceased. Who this helps: This helps forensic scientists and law enforcement in accurately determining the time of death in drug-related cases.