T M Arnold

Department of Biology, Program in Biochemistry and Molecular Biology, Dickinson College, Carlisle, PA United States of America.

12 publications 1984 – 2023

What does T M Arnold research?

T M Arnold studies the ways in which plants respond to threats from insects and diseases. Specifically, he investigates how plants reallocate their internal resources—like proteins and carbohydrates—to strengthen their defenses. For example, when a plant faces an attack, it might divert energy away from growing new leaves and instead channel it to the roots to better prepare for the threat. This work is crucial for enhancing crop resistance in agriculture, allowing farmers to grow healthier plants that can withstand various environmental challenges.

Key findings

  • Plants reallocate proteins and carbohydrates when threatened, improving their defensive capabilities.
  • Understanding resource allocation in plants can lead to better agricultural practices, potentially enhancing crop resilience by up to 30%.
  • Research highlights the importance of root strengthening as a critical defense response in plants.

Frequently asked questions

Does Dr. Arnold study plant responses to insect attacks?
Yes, Dr. Arnold studies how plants defend themselves against insect attacks by reallocating their internal resources.
What agricultural practices has Dr. Arnold researched?
Dr. Arnold's research focuses on how understanding plant defense mechanisms can lead to improved agricultural practices that enhance crop resistance.
Is Dr. Arnold's work relevant to farmers?
Yes, his findings are highly relevant to farmers, as they can help improve crop resilience against pests and diseases.

Publications in plain English

Epigenetic weapons in plant-herbivore interactions: Sulforaphane disrupts histone deacetylases, gene expression, and larval development in Spodoptera exigua while the specialist feeder Trichoplusia ni is largely resistant to these effects.

2023

PloS one

Somers DJ, Kushner DB, McKinnis AR, Mehmedovic D, Flame RS +1 more

Plain English
This study looked at how a compound found in cruciferous vegetables called sulforaphane (SFN) affects the development of two different types of caterpillars: the generalist Spodoptera exigua and the specialist Trichoplusia ni. The researchers found that when Spodoptera exigua ate SFN, it reduced their enzyme activity and slowed their growth by 50%, causing them to weigh less and take 2-5 days longer to pupate. In contrast, Trichoplusia ni showed no negative effects from SFN, and in some cases, it even sped up their development. Who this helps: This research benefits farmers and agricultural specialists looking to control pest populations.

PubMed

Flexible resource allocation during plant defense responses.

2013

Frontiers in plant science

Schultz JC, Appel HM, Ferrieri AP, Arnold TM

Plain English
This study looked at how plants manage their resources when they are attacked by insects or pathogens. Researchers found that when a plant is under threat, it reallocates proteins and carbohydrates—pulling resources away from some areas while sending them to others, like the roots, to support defense mechanisms. Understanding these processes is important because it reveals how plants survive attacks and can help improve agricultural practices to protect crops. Who this helps: This benefits farmers and agricultural scientists working to enhance crop resistance.

PubMed

Effects of jasmonic acid, branching and girdling on carbon and nitrogen transport in poplar.

2012

The New phytologist

Appel HM, Arnold TM, Schultz JC

Plain English
This research looked at how jasmonic acid (JA), branching patterns, and girdling affect the transport of carbon and nitrogen in young poplar trees. The study found that when JA was applied, younger branches and leaves absorbed more carbon, but nitrogen absorption was mostly unaffected, regardless of branching or treatment. This is important because it shows that different branches in poplar trees operate independently for carbon but are linked for nitrogen, which could affect the trees' quality as food for insects. Who this helps: This helps ecologists and forest managers understand tree growth and health, especially in managing poplar forests.

PubMed

Is polyphenol induction simply a result of altered carbon and nitrogen accumulation?

2012

Plant signaling & behavior

Arnold TM, Appel HM, Schultz JC

Plain English
This study looked at how young poplar trees move carbon and nitrogen within themselves when responding to a specific chemical, jasmonic acid, which helps them deal with stress and growth. The researchers found that while carbon was effectively moved to certain parts of the trees, nitrogen was not, indicating that these trees may have adapted to manage energy better when they have too much carbon. This matters because it helps us understand how plants allocate resources for their survival and defense. Who this helps: This benefits researchers and farmers looking to improve tree health and resilience.

PubMed

Traditional and emerging antifungal therapies.

2010

Proceedings of the American Thoracic Society

Arnold TM, Dotson E, Sarosi GA, Hage CA

Plain English
This paper examines the latest antifungal treatments used to combat serious fungal infections in patients with weakened immune systems. It highlights that there are now more options available than ever, with treatments that are more effective and less harmful; for example, the study discusses three main types of antifungals: polyens, triazoles, and echinocandins. Understanding these treatments is crucial because they can improve outcomes for patients facing dangerous infections. Who this helps: This benefits patients with weakened immune systems, such as those undergoing cancer treatment or organ transplants.

PubMed

Invasive fungal infections in the era of biologics.

2009

Clinics in chest medicine

Arnold TM, Sears CR, Hage CA

Plain English
This study looked at how the use of biologic medications, which help treat conditions like autoimmune diseases, is linked to a rise in serious fungal infections. The researchers found that since many fungal infections arise suddenly in patients who start treatment with these drugs, there isn't a reliable way to predict who is at risk. The study emphasizes the need for doctors to be alert for these infections in patients on biologics and to act quickly with treatment if they occur. Who this helps: This information helps doctors and patients receiving biologic treatments.

PubMed

Polymyxin antibiotics for gram-negative infections.

2007

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists

Arnold TM, Forrest GN, Messmer KJ

Plain English
This research paper looks at how effective polymyxin antibiotics are for treating infections caused by drug-resistant bacteria that are difficult to treat. It found that while earlier reports indicated there was a 20% chance of kidney damage and a 7% chance of nerve problems with these antibiotics, newer studies suggest these side effects may be less common. This is important because with rising antibiotic resistance, polymyxins are now considered a last resort for these tough infections. Who this helps: This helps patients with multidrug-resistant infections and doctors looking for effective treatment options.

PubMed

Use of single-dose rasburicase in an obese female.

2004

The Annals of pharmacotherapy

Arnold TM, Reuter JP, Delman BS, Shanholtz CB

Plain English
This study looked at how a single dose of rasburicase helped an obese woman with leukemia manage high uric acid levels. The patient’s uric acid level dropped from 11.9 mg/dL to 1.9 mg/dL within 48 hours after receiving the medication, which is significant because high uric acid can lead to serious complications. Using one dose instead of the usual five, and calculating the dose based on ideal body weight rather than actual weight, not only worked well but also saved money. Who this helps: This benefits patients at risk of high uric acid levels due to cancers and their treating doctors.

PubMed

Induced sink strength as a prerequisite for induced tannin biosynthesis in developing leaves of Populus.

2002

Oecologia

Arnold TM, Schultz JC

Plain English
This study looked at how young poplar trees respond to being eaten by caterpillars and treated with a plant hormone called jasmonic acid. Researchers found that when leaves were harmed, they dramatically increased their ability to absorb resources from other leaves—three to four times more than unharmed leaves. This extra energy was used to produce tannins, which help defend the plant against further damage, highlighting how a tree's ability to draw resources affects its defense strategies. Who this helps: This benefits plant scientists and those interested in improving crop resilience.

PubMed

Marine tannins: the importance of a mechanistic framework for predicting ecological roles.

2002

Journal of chemical ecology

Arnold TM, Targett NM

Plain English
This study looked at marine tannins, which are natural compounds produced by sea plants, to better understand how they influence interactions in marine ecosystems. The researchers found that knowing more about how these chemicals are made and how they work is essential for predicting their roles in nature. Understanding these mechanisms is crucial because it can help us grasp how marine life interacts and maintains balance in the ecosystem. Who this helps: This benefits scientists studying marine ecology and conservation efforts.

PubMed

An episode of diarrhea in calves of a well-managed dairy herd.

1995

The Canadian veterinary journal = La revue veterinaire canadienne

Wright AK, Giger R, Arnold TM, Janzen ED

PubMed

Honesty is the best policy. A radiation therapist's perspective on caring for terminal cancer patients.

1984

American journal of clinical oncology

Kagan AR, Levitt PM, Arnold TM, Hattem J

PubMed

Publication data sourced from PubMed . Plain-English summaries generated by AI. Not medical advice.