Wenzhen Lv

State Key Laboratory of Bioactive Molecules and Druggability Assessment, The Biomedical Translational Research Institute, Health Science Center (School of Medicine), Jinan University, Guangzhou, 510632, China.

50 publications 2025 – 2026 ORCID

What does Wenzhen Lv research?

Wenzhen Lv studies the immune system's role in fighting diseases, focusing on proteins that help keep immune cells like natural killer (NK) cells alive and functional. They specifically investigate treatments for aggressive cancers, like triple-negative breast cancer, examining how natural mixtures may help slow tumor growth and promote cancer cell death. Additionally, they explore the implications of chronic illnesses such as lung cancer and tuberculosis, providing insights on how to better manage patients with co-existing conditions. Their research also delves into agricultural practices, looking at how to enhance livestock health and productivity while addressing environmental challenges such as soil salinity.

Key findings

  • Liver kinase B1 (Lkb1) deficiency leads to NK cell death due to an overload of harmful substances, impairing the immune response against tumors.
  • The Hongwu mixture reduced the survival rate of triple-negative breast cancer cells by promoting cancer cell death, indicating its potential as a new treatment.
  • In patients co-diagnosed with lung cancer and tuberculosis, those with lung cancer diagnosed first had a median survival of 57 months, while TB-first patients lived for about 32 months.
  • Using bacterial vaccines could significantly reduce antibiotic use, helping to combat antibiotic-resistant infections.
  • Low doses of hydrazine improved nitrogen removal rates in wastewater treatment systems by 386.6%, enhancing environmental management practices.

Frequently asked questions

Does Wenzhen Lv study cancer treatment?
Yes, Wenzhen Lv's research includes studying potential treatments for various types of cancer, especially aggressive forms like triple-negative breast cancer.
What other health issues does Wenzhen Lv focus on?
They also investigate immune system disorders, tuberculosis, and the impact of medications on cancer risk.
How does Wenzhen Lv's work impact agriculture?
Their research looks at improving livestock health and management practices, particularly in understanding how environment and veterinary care affect breeding outcomes.
Are Wenzhen Lv's findings relevant to patients with lung cancer?
Yes, their work provides insights that can help healthcare providers make better treatment decisions for patients dealing with lung cancer and other related conditions.
What role do vaccines play in Wenzhen Lv's research?
They examine how bacterial vaccines can reduce the necessity for antibiotics, addressing the issue of antibiotic resistance in bacterial infections.

Publications in plain English

Spacer cations: molecular switches for 2D and 2D/3D perovskite photovoltaics.

2026

Nanoscale

Gao G, Yan H, Lv W, Li M, Xia J +4 more

Plain English
Researchers studied how large organic molecules, called spacer cations, can improve the stability and efficiency of perovskite solar cells, which have already achieved power conversion efficiencies above 27%. They found that using these spacer cations allows for better control over the materials' structure and properties, leading to more reliable solar technology. This is important because it makes solar energy more viable for widespread use and could overcome current limitations that hold back traditional perovskite solar cells. Who this helps: This benefits solar energy developers and consumers looking for reliable renewable energy sources.

PubMed

DNA Hypermethylation Suppresses Thyroid Peroxidase Expression and May Be a Promising Diagnostic Marker for Thyroid Cancer.

2026

Thyroid : official journal of the American Thyroid Association

Zhu L, Jiang K, Huang J, Zhang Q, Chen Y +5 more

Plain English
This study looked at how changes in DNA, specifically increased methylation, affect the levels of a protein called thyroid peroxidase (TPO) in thyroid cancer. Researchers found that higher levels of DNA methylation were linked to much lower TPO expression, which could help differentiate between cancerous and non-cancerous thyroid growths. The method they developed to measure these changes showed high accuracy, with diagnostic performance scores of 0.927 and 0.916, indicating its potential as a reliable way to identify thyroid cancer early. Who this helps: This helps patients by potentially improving early detection of thyroid cancer.

PubMed

The Effect of Standardized Postoperative Neck and Orofacial Rehabilitation Exercise on Quality of Life in Post-Thyroidectomy Patients: A Randomized Controlled Trial.

2026

Thyroid : official journal of the American Thyroid Association

Huang J, Chen W, Zhang J, Xu H, Li Y +6 more

Plain English
This study looked at the impact of a specific set of neck and mouth exercises on the quality of life, focusing on swallowing, for patients who had their thyroid removed but did not suffer nerve damage during surgery. The results showed that those who did the exercises reported better swallowing quality of life scores one month after surgery (97.4 compared to 88.9) and again at six months (100 compared to 98.9). This is important because it demonstrates that structured rehabilitation can significantly improve recovery for these patients. Who this helps: This helps patients recovering from thyroid surgery.

PubMed

The Efficacy of Gut Microbiome-Modulating Therapies on Liver Cirrhosis: A Systematic Review and Network Meta-Analysis.

2026

Clinical and translational gastroenterology

Wang Y, OuYang J, Zhang H, Shen Y, Guo Z +1 more

Plain English
This study looked at different treatments that change gut bacteria to see how they help people with liver cirrhosis, a serious liver condition. After analyzing 17 studies with a total of 1,051 patients, they found that synbiotics (a mix of probiotics and prebiotics) were the most effective at lowering harmful blood ammonia levels by an average of 5.57 units compared to no treatment. Prebiotics were also beneficial, significantly reducing levels of toxins and inflammation-linked substances. This matters because it offers clear options for doctors to personalize treatment based on whether patients have high ammonia or inflammation. Who this helps: Patients with liver cirrhosis.

PubMed

BIRC3 and NOC2L synergistically promote P53 acetylation to accelerate necroptosis in sepsis-associated acute kidney injury.

2026

Biochimica et biophysica acta. Molecular basis of disease

Ma X, Wang Y, Diao R, Yin M, Shen Q +3 more

Plain English
This study looked at how certain proteins in the kidneys of rats with sepsis-associated acute kidney injury (SA-AKI) affect cell death and kidney damage. Researchers found that the protein BIRC3 significantly increased the acetylation of another protein called P53, leading to a type of cell death known as necroptosis, which worsened kidney injury. By measuring this process, they identified that combining BIRC3 and another protein, NOC2L, plays a critical role in promoting this harmful cell death, suggesting that targeting these proteins could offer new treatments for patients suffering from kidney injuries due to sepsis. Who this helps: This research can help patients with sepsis-related kidney injuries by leading to new treatment options.

PubMed

The asynchronous response of structure and functionality of soil nematode community to Tibetan sheep grazing in an alpine grassland on the eastern Qinghai-Tibet Plateau.

2026

Journal of environmental management

Sun C, Dong Q, Lv W, An H, Liu Y +3 more

Plain English
Researchers studied how different levels of grazing by Tibetan sheep affect soil nematodes, tiny worms that are important for soil health, in the grasslands of the Qinghai-Tibet Plateau. They found that heavy grazing led to a 17% drop in the number of nematodes and changed the types of nematodes present, with certain species becoming more dominant as grazing increased. Understanding these changes is important because it helps us grasp the effects of overgrazing on soil health and could guide efforts to restore degraded grasslands. Who this helps: This helps farmers, land managers, and environmentalists focused on sustainable grazing practices.

PubMed

Letter to the Editor: Live Birth Outcomes After Extended or Repeated High-Dose Medroxyprogesterone Acetate Therapy for Fertility-Sparing Management of Endometrial Neoplasia: A Single-Center Retrospective Case Series.

2026

The journal of obstetrics and gynaecology research

Chen Y, Lv W

PubMed

Biodegradable mulch films divergently regulate soil carbon cycle by reshaping microbial communities and functional genes.

2026

Journal of hazardous materials

Zhang H, Yu S, Lv W, Wang X, Lu P +6 more

Plain English
This study looked at how two types of biodegradable mulch films (BM1 and BM2) and a traditional plastic mulch film affected soil microorganisms involved in the carbon cycle. After one month, the biodegradable mulch films increased the variety of these microorganisms by over 32%, but this effect faded by the seventh month. The findings show that BM1 enhanced certain genes related to breaking down carbon while suppressing others, highlighting how these biodegradable options can change soil health and carbon processing. Who this helps: This research benefits farmers and agricultural workers looking for sustainable soil management practices.

PubMed

Using supplementary formula of Qing-Hao-Bie-Jia decoction for defervescence of lung cancer-related fever: a literature review and case report.

2026

Frontiers in medicine

Chu XG, Zhang WH, Luo B, Yang F, Lv WM +2 more

Plain English
This study looked at a traditional Chinese medicine formula called Qing-Hao-Bie-Jia Decoction (QHBJD) to help reduce fevers in lung cancer patients. It found that these patients often experience fever due to a condition described as "latent heat in the Yin," and using QHBJD may help nourish the body's balance and alleviate this fever. By reviewing ancient texts, current case reports, and a specific patient case, the researchers developed a framework for combining old and new methods to improve treatment approaches. Who this helps: This benefits lung cancer patients experiencing fevers.

PubMed

Gut fungal signatures predict disease status in acute ischemic stroke.

2026

iScience

Yan Q, Pu L, Yuan S, Zhang Z, Lv W +5 more

Plain English
This study looked at the types of fungi present in the guts of people who had an acute ischemic stroke (AIS) and compared them with healthy individuals. Researchers found that people with AIS had a significantly different gut fungal profile than healthy people, allowing them to predict the severity of the stroke and potential outcomes with high accuracy (up to 95%). Understanding these gut fungi may help doctors assess patients’ conditions better after a stroke. Who this helps: Patients who have suffered a stroke and their healthcare providers.

PubMed

Cost-effectiveness of hetrombopag, eltrombopag, and avatrombopag for chronic immune thrombocytopenia in China: a cost-utility analysis.

2026

Frontiers in public health

Jin S, Hu Z, Jin Y, Lv W, Song Z +2 more

Plain English
This study looked at three treatments for chronic immune thrombocytopenia (ITP) in China: hetrombopag, eltrombopag, and avatrombopag. The researchers found that hetrombopag was the cheapest option at about 2.2 million Chinese Yuan and provided nearly as much health benefit as the more expensive avatrombopag, making it the most cost-effective choice for patients. This matters because cost-effective treatments can help the healthcare system manage resources better while still providing good care to patients. Who this helps: This helps patients with chronic ITP and healthcare providers in China.

PubMed

The bile acid sodium symporter SlBASS4 enhances tomato salt tolerance.

2026

Horticulture research

Ma N, Xin X, Zhu G, Wang T, Liu Y +2 more

Plain English
This study looked at a specific protein in tomatoes that helps the plants cope with high salt levels in the soil. Researchers found that when this protein (called SlBASS4) was more active, the tomatoes could better survive salty conditions, showing improvements like a 25% increase in weight and healthier leaves compared to regular plants. This research is important because it could lead to more resilient tomato varieties that thrive in salty environments, which are becoming more common due to climate change. Who this helps: Patients and consumers benefit from more sustainable and resilient tomato crops.

PubMed

Design of insulating ceramic cells for in situ high-pressure nuclear magnetic resonance.

2026

The Review of scientific instruments

Jin K, Zheng S, Sui Y, Wang J, Wang S +9 more

Plain English
This study looked at a new type of device, made from special ceramics, that improves a technique called high-pressure nuclear magnetic resonance (HP-NMR), which helps scientists understand how materials change under high pressure. The researchers found that their ceramic device can work efficiently at pressures up to 8.5 gigapascals and doubled the quality of the signals they can measure. This is important because it allows better study of materials under extreme conditions, which can lead to new discoveries in material science. Who this helps: This helps researchers and scientists studying materials under high-pressure conditions.

PubMed

Reduced eccDNA content in idiopathic asthenozoospermia sperm is associated with compromised DNA repair capacity and elevated DNA damage.

2026

Cellular & molecular biology letters

Wang Z, Song C, Hong X, Yu J, Xu Z +26 more

PubMed

GPU-accelerated linkage disequilibrium scans reveal non-independent assortment of human non-homologous chromosomes.

2026

Genome biology

Lv W, Zou Y, Shang Z, Wei S, Sun C +11 more

Plain English
This study examined how genes on different chromosomes behave during reproduction in 26 human populations. Researchers used advanced computing to analyze data from nearly 2,600 samples and found that many genes on separate chromosomes are linked more closely than expected, particularly near the centers of chromosomes, with 1,195 pairs showing strong connections. This finding challenges a long-held belief in genetics that genes on non-homologous chromosomes act independently, which could influence how we understand genetic variations in different populations. Who this helps: This research benefits geneticists and researchers studying human heredity and population genetics.

PubMed

DDX21 Linksand TERT to Promote Thyroid Cancer Progression.

2026

Thyroid : official journal of the American Thyroid Association

Chen M, Jiang K, Zhang Q, Xiao X, Zhu L +7 more

Plain English
This study examined how the proteins DDX21 and TERT work together to promote the progression of thyroid cancer. Researchers found that when DDX21 is increased in thyroid cancer cells, it helps raise levels of TERT, a known marker of aggressive cancer. Specifically, knocking down DDX21 reduced the activity of cancer-related genes and slowed cell growth and movement, indicating that targeting DDX21 could be a potential treatment strategy for patients with this type of cancer. Who this helps: This helps patients with thyroid cancer, especially those with specific genetic alterations.

PubMed

Catalyzing Li-Salt Dissociation and Decomposition for a Conformal Low-Impedance Solid Electrolyte Interphase in Solid-State Li Metal Batteries.

2026

Journal of the American Chemical Society

Zhao Y, Shi J, Yang H, Geng C, Hu Z +8 more

Plain English
This study looked at improving solid-state lithium metal batteries by using a molecule called Hemin to help lithium salts dissolve better and create a more stable surface at the battery's lithium electrode. Researchers found that using Hemin increased the amount of free lithium from 22% to 44% and improved the battery's ability to conduct ions, which is crucial for performance. This is important because it allows the batteries to last much longer, operating reliably for over 6000 hours and maintaining stable performance over 2000 cycles even under high-use conditions. Who this helps: This benefits battery manufacturers and consumers seeking more efficient and longer-lasting batteries.

PubMed

Strengthened Built-In Electric Field in Sulfur-Doped BiOBr Facilitates Exciton Dissociation and Boosts Photocatalytic Activity.

2026

Langmuir : the ACS journal of surfaces and colloids

Shen L, Li Z, Li D, Wen C, Fang Z +6 more

Plain English
This study focused on improving a material called BiOBr for breaking down pollutants more effectively using light, by adding sulfur to it. The researchers found that the sulfur made the material work 8 times better at degrading a specific drug, sulfisoxazole, compared to the unmodified version. This matters because more efficient pollutant removal can lead to cleaner environments and better public health. Who this helps: Patients who may be affected by pharmaceutical pollution and researchers developing new waste treatment technologies.

PubMed

Computational Insights into the Relationship Between Solution Concentration and Adsorption Energy.

2026

Molecules (Basel, Switzerland)

Lv W, Zhou W, Nie M, Yao C, Wang Z +3 more

Plain English
This study examined how the concentration of certain ions (specifically chlorine and sulfur) affects their ability to cling to metals like aluminum and copper, which is important for understanding corrosion. Researchers found that as the concentration of these ions increased, the strength of their attachment to the metal surfaces became slightly stronger, with the energy required for adhesion increasing by about 20 to 90 millielectronvolts, depending on the type of metal and its surface. This is important because understanding these interactions can help improve the durability of metals in environments where they are prone to corrosion. Who this helps: This helps engineers and material scientists working on corrosion prevention.

PubMed

The Transcription FactorAlleviates Chilling Injury by Improving Cold Resistance of Kiwifruit 'Taishan 1'.

2026

Plants (Basel, Switzerland)

Guo Q, Zhou M, Xun M, An M, Han H +6 more

Plain English
This study focused on a type of kiwifruit called 'Taishan 1', which has trouble staying fresh during cold storage and transportation. Researchers found a key gene that helps this fruit resist cold damage and discovered that enhancing this gene improved the fruit's ability to withstand cold stress. This matters because it could lead to better ways to store kiwifruit, reducing spoilage and waste. Who this helps: This helps farmers and the fruit industry by improving the shelf life of kiwifruits.

PubMed

Nanoscale insights into cellulose-imidazolium ionic liquid interactions via atomic force microscopy.

2026

Carbohydrate polymers

Cao R, Gao H, Lv W, Song Y, Long Y +4 more

Plain English
This study looked at how cellulose interacts with different liquids at a tiny scale to understand its properties better. The researchers found that replacing certain groups in cellulose reduced its bonding forces by up to 60.3%, and using specific ionic liquids significantly decreased these forces by 84.5%. These findings are important because they can help improve the way cellulose is dissolved and processed for use in various products, making them stronger and more effective. Who this helps: This benefits manufacturers and researchers working with cellulose-based materials.

PubMed

A new indoloquinoline-based fluorescence probe for imaging of hydrazineand.

2026

RSC advances

Zhang C, Tang S, Wu J, Lv W, Li J +1 more

Plain English
Researchers created a new fluorescent probe that can quickly and accurately detect hydrazine, a substance that can harm the environment. The probe works effectively by responding rapidly and showing strong results without being toxic to living cells. This development is crucial because it allows scientists to monitor hydrazine levels in living animals, which can help protect ecosystems from damage. Who this helps: This benefits environmental scientists and wildlife researchers.

PubMed

Development and evaluation of a predictive model based on multi-frequency magnetic resonance elastography for high-risk esophagogastric varices in patients with cirrhotic portal hypertension.

2026

Insights into imaging

Lv W, Yu L, Wang L, Tang S, Yuan J +4 more

Plain English
This study looked at patients with liver cirrhosis to assess the risk of serious complications from enlarged veins in the esophagus and stomach, known as esophagogastric varices (EGV). Researchers used a technique called multi-frequency magnetic resonance elastography (MRE) to measure the stiffness of the liver and spleen in 54 patients. They found that higher stiffness in the spleen and larger diameter of the portal vein indicated a higher risk of serious EGV, allowing for a new predictive model to identify patients at risk effectively. Who this helps: This research benefits patients with cirrhosis by guiding doctors to provide timely treatment and reduce the risk of dangerous bleeding.

PubMed

Enhanced low-temperature NH-SCR activity and SOtolerance by Cu-SSZ-13/R(Sm, Pr, Y or La)MnOcoupled catalysts.

2026

Dalton transactions (Cambridge, England : 2003)

Lv W, Jiang X, Wei G, Wei R, Sun F +5 more

Plain English
This study looked at a new type of catalyst made from copper and other materials to improve the removal of nitrogen oxides, harmful pollutants, at lower temperatures. Researchers found that the combination of copper with a material called SmMnO significantly boosted this pollutant removal by up to 90% at low temperatures while also resisting sulfur, which can harm other catalysts. This is important because it can help create cleaner air by making catalytic converters in vehicles and industrial processes more effective. Who this helps: This benefits both manufacturers of catalytic converters and the general public by reducing harmful emissions.

PubMed

Fully Bio-Based, Tough, and Room-Temperature Shape Adaptive Poly(lactic acid) Blend for Green Electronics.

2026

ACS macro letters

Lv W, Ma J, Gu C, Su Y, Huang J +4 more

Plain English
This study focused on improving a sustainable material called poly(lactic acid) (PLA), which is commonly used in electronics but is normally too brittle and not flexible enough. Researchers developed a new blend of PLA and another bio-based material that made it tougher and able to hold its shape even at room temperature. They achieved impressive results, with the toughened PLA blend showing a strength of nearly 40 megapascals and excellent shape retention in various forms, which means it can better protect electronic components. Who this helps: This research benefits manufacturers of green electronics by providing a more durable, flexible material that reduces e-waste.

PubMed

The bidirectional ecological effects of earthworms on antibiotics and resistance genes in soil ecosystems: Health risks under one health framework.

2026

Ecotoxicology and environmental safety

Xu C, Zhu C, Duan Y, Xie B, He D +2 more

Plain English
This research looked at how earthworms affect antibiotics and antibiotic resistance genes (ARGs) in farm soils. The study found that earthworms help break down antibiotics and reduce the spread of ARGs, but they can also suffer negative effects from antibiotics, which can hinder their growth and health. This is important because it highlights the balance needed to manage soil health while preventing antibiotic resistance, which affects both the environment and public health. Who this helps: This helps farmers, environmentalists, and public health officials.

PubMed

Silica distributed-feedback fiber laser beyond 2.1 µm.

2026

Optics express

Shi J, Lv W, Zhang Z, Feng X

Plain English
This study looked at a new type of silica fiber laser that can produce very short pulses of light at a wavelength between 2.1 and 2.2 micrometers, which is useful for sensing and biological applications. The researchers created a laser that produces output at 2112 nanometers with a peak power of nearly 30 watts and discovered that it could maintain a single frequency, which is important for accuracy. This advancement could help improve remote sensing technologies and biological detection methods, making them more effective. Who this helps: This benefits researchers and industries involved in remote sensing and medical diagnostics.

PubMed

Effects of L-citrulline supplementation in the basal diet on reproductive performance, serum metabolites, and microbial community structure in Simmental cows.

2026

Frontiers in microbiology

Li C, Chen H, Liu J, Zao W, Fan C +6 more

Plain English
Researchers studied the impact of adding L-citrulline, an amino acid, to the diets of Simmental cows to see how it would affect their reproductive health. They found that cows given 7 grams of L-citrulline per day had a 12.5% higher estrus rate, while those given 14 grams showed significant increases in two important reproductive hormones, gonadotropin-releasing hormone and follicle-stimulating hormone, by 15.79% and 35.71% respectively. This matters because improved hormone levels can lead to better chances of pregnancy in cows, enhancing reproductive performance and productivity in the dairy industry. Who this helps: This helps dairy farmers and livestock producers looking to improve cow fertility and milk production.

PubMed

Ecological impacts of herbicide control in a protected coastal wetland of Chongming Island (Yangtze River Estuary, eastern China) assessed using macrobenthic indicators.

2026

Marine pollution bulletin

Zhu T, Yang L, Liu H, Qiu S, Jiang Q +2 more

Plain English
This study looked at how using herbicides to control an invasive plant species, Spartina alterniflora, affected the tiny creatures living in the mud of a protected wetland in China. Researchers found that certain areas treated with the herbicide caused a significant decline in the variety and health of these creatures, especially those that initially had low diversity, with some regions showing only partial recovery after one year. In contrast, areas with higher initial diversity showed more resilience to the spray. Who this helps: This research helps wetland managers and conservationists make better decisions about controlling invasive species while protecting local ecosystems.

PubMed

Rougher, wetter, weaker: Multiscale evidence and mechanisms of tetramethylammonium hydroxide-induced anammox granule collapse.

2026

Journal of hazardous materials

Zhang Y, Dong ZH, Zhu YF, Lv WN, Yang J +2 more

Plain English
This research studied how wastewater containing a chemical called tetramethylammonium hydroxide (TMAH) affects the stability of specialized bacteria clusters known as anammox granules, which are important for waste treatment. The results showed that long-term exposure to TMAH caused the granules to become rougher and more water-attracting, leading to serious damage in their structure. Specifically, the roughness increased five times, and while the bacterial population remained high at 37.73%, their ability to function dropped dramatically, indicating they were under stress and not working effectively. Who this helps: This research benefits wastewater treatment facilities and environmental engineers working to manage industrial waste.

PubMed

Extrachromosomal DNA in urothelial carcinoma: mechanisms and clinical applications.

2026

Nature reviews. Urology

Li C, Hu Z, Zhang W, Ji Y, Wang F +5 more

Plain English
This study focused on the role of extrachromosomal DNA (ecDNA) in a type of bladder cancer called urothelial carcinoma. Researchers found that ecDNA plays a key role in making the cancer more unstable and aggressive by amplifying cancer genes and influencing how tumor cells interact with the immune system. Because ecDNA can be detected in urine and blood tests, it could be very useful for early diagnosis, selecting the right treatments for patients, and monitoring their response to therapy. Who this helps: Patients with urothelial carcinoma and their doctors.

PubMed

Tetrahydropalmatine Alleviates Osteoarthritis-Associated Pain and Inflammation by Suppressing KDM4A/MDM2/HIF-1α-Mediated M1 Macrophage Polarization.

2026

Chemical biology & drug design

Chen X, Sun X, Zhong Q, Gan H, Lv W +1 more

Plain English
This study looked at how a compound called tetrahydropalmatine (THP) can reduce pain and inflammation caused by osteoarthritis (OA). Researchers found that THP significantly lessened both pain and damage in OA models, reducing markers of inflammation and macrophage activity by about 50-70%. This is important because it points to THP as a potential new treatment that could improve the lives of people suffering from osteoarthritis-related pain and inflammation. Who this helps: Patients with osteoarthritis and their healthcare providers.

PubMed

Emerging pathological mechanisms of Alzheimer's disease pathogenesis: from neuroimmune interactions to intercellular communication.

2026

Frontiers in aging neuroscience

Wang R, Feng Y, Zhou Z, Jiang J, Zhang R +4 more

Plain English
This research paper looks at new ways to understand Alzheimer's disease (AD), moving beyond the traditional focus on amyloid-beta build-up. It found that certain brain cells, called microglia and astrocytes, become dysfunctional during the disease, contributing to inflammation and nerve damage. Specifically, transformed microglia reduce their ability to clear amyloid-beta and release harmful substances, while astrocytes lose their protective functions and become toxic. This matters because targeting these new mechanisms could lead to better treatments for Alzheimer's. Who this helps: This research helps patients with Alzheimer's and their caregivers by guiding the development of more effective therapies.

PubMed

Hydrazine-driven granulation and functional differentiation in partial nitrification-anammox systems: size-dependent metabolic shifts and microbial succession.

2026

Bioresource technology

Wan X, Chen Y, Liu S, Sun W, Lv W +3 more

Plain English
This study explored how a compound called hydrazine can improve the efficiency of systems that remove nitrogen from wastewater. Researchers found that using a low dose of hydrazine resulted in a 386.6% increase in nitrogen removal rates compared to standard methods. This improvement is significant because it leads to more effective wastewater treatment, maintaining stability for 33 days after hydrazine was no longer added. Who this helps: This benefits wastewater treatment plants and their operators.

PubMed

Wu Zi Yan Zong Wan enhances sperm quality in boars by regulating spermatogenesis-related pathways and gut microbiota.

2026

Frontiers in veterinary science

Lv W, Gao X, Zhao H, Cao M, Zhou L +5 more

Plain English
This study looked at how a Traditional Chinese Medicine formula called Wu Zi Yan Zong Wan affects sperm quality in breeding boars with poor sperm health. After 8 weeks of treatment, the researchers found that sperm motility, volume, and density improved significantly, with sperm deformities reduced. This matters because enhancing sperm quality can help extend the reproductive lifespan of these animals, which is important for breeding efficiency. Who this helps: This helps farmers and breeders of boars looking to improve reproduction rates.

PubMed

Secondary salinization in facility agricultural soils detrimentally affects the spatial distribution of earthworm communities: dominant drivers and ecological risks.

2026

Journal of environmental management

Zhang Y, Wu Y, Wang M, Jiang R, Xu Y +5 more

Plain English
Researchers examined how increasing salt levels in agricultural soils—especially in greenhouses—affect earthworm populations, which are important for healthy soil. They found that greenhouse soils had much higher salt and nitrogen levels compared to open-field soils, leading to a 50.8% decline in earthworm numbers and a 61.6% drop in their biomass. This is important because earthworms help maintain soil fertility, and understanding how salt affects them can guide better agricultural practices. Who this helps: This information benefits farmers and agronomists looking to improve soil health and crop yields.

PubMed

Unraveling the Intercalation-Mediated Phase Transformation and Epitaxy at the Mn/MoSHeterointerface.

2026

ACS applied materials & interfaces

Yu M, Ding J, Zhang Z, Zhang Y, Li Y +3 more

Plain English
This study looked at how different materials interact at the atomic level, specifically at the interface between manganese (Mn) and molybdenum disulfide (MoS). The researchers found that at 500°C, adding manganese changes the structure of the materials in a precise way, creating a new phase and improving the quality of the interface. By raising the temperature to 600°C, the materials achieved a more stable and sharp separation between them, which is important for creating better electronic devices. Who this helps: This benefits researchers and engineers working on advanced electronic materials.

PubMed

Causal effects of drug exposure on gastric cancer risk: a Mendelian randomization study involving 23 commonly used medications in the European population.

2026

Discover oncology

Zhang G, Xia J, Zhou Y, Qian J, Yin D +1 more

Plain English
This study looked at whether 23 commonly used medications affect the risk of developing gastric cancer in European populations. The researchers found that specific types of drugs, like those used for migraines and certain antihypertensives, may lower the risk of gastric cancer by about 17% to 14%. This is important because understanding how medications influence cancer risk could lead to better prevention strategies. Who this helps: Patients and doctors managing cancer risk.

PubMed

Chinese Position Paper on Biologic Therapy for Allergic Rhinitis.

2026

Allergy

Zhang Y, Li J, Li X, Wang M, Yang X +33 more

Plain English
This paper examines the use of biologic therapies for people suffering from allergic rhinitis, a common condition that causes sneezing and a runny nose. Researchers found that existing treatments often don’t work for many patients, but new biologic options like stapokibart show promise, especially for those with seasonal allergic rhinitis. The study aims to guide doctors on when to use these treatments and improve care for patients who do not find relief with traditional therapies. Who this helps: This helps patients with allergic rhinitis who are not responding well to standard treatments.

PubMed

Extrusion-based 3D printing of starch/PVA composite films: Structure-property relationships and application in fruit preservation.

2026

Food chemistry

Li G, Wang B, Lv W, Xiao H

Plain English
This study explored how different types of starch combined with polyvinyl alcohol (PVA) can be 3D printed into films for food packaging. They found that a specific tapioca starch (TS2) resulted in the best film performance, with a strength of 27.6 MPa, and reduced gas permeability, making it effective for extending the shelf life of fruits from 2 to 5 days while keeping them firm. This research is important as it could lead to more sustainable packaging solutions that keep food fresher for longer. Who this helps: This benefits food manufacturers and retailers looking for better ways to preserve fruits.

PubMed

Corrigendum to "Effects of vacuum steam pulsed blanching on bioactive compounds, quality attributes, enzyme activities, and microstructural properties of daylily (Hemerocallis citrina Baroni)" [Food Chem. 506 (2026) 148147].

2026

Food chemistry

Zhang J, Deng LZ, Zhang WP, Xu MQ, Shi YS +6 more

PubMed

Case Report: Simultaneous presence ofand fungal elements in scrapings from a patient with bullous pemphigoid.

2026

Frontiers in medicine

Ye Y, Lv W, Chai L, Li Q, Liu Z +1 more

Plain English
This study looked at a patient with bullous pemphigoid, a skin condition, who developed crusted scabies and a fungal infection after starting treatment with glucocorticoids, a type of steroid medication. The report highlights that even low doses of these steroids, below 5 mg, can increase the risk of infections. Recognizing this risk is important because it helps doctors make safer treatment choices for patients on glucocorticoids. Who this helps: This helps patients being treated with glucocorticoids and their doctors.

PubMed

From Antibiotic Resistance to Bacterial Vaccines: A New Approach to Controlling Resistant Bacterial Infections.

2026

Infection and drug resistance

Xiong F, Fang X, Lu Y, Lv W

Plain English
This study looks at how bacterial vaccines can help fight infections caused by antibiotic-resistant bacteria, a major global health threat. It found that vaccines can reduce the need for antibiotics and lower the chances of bacteria becoming resistant. For instance, using vaccines could significantly cut down on antibiotic use and help prevent the spread of resistant strains, even as challenges in developing these vaccines remain. Who this helps: Patients dealing with bacterial infections, especially those resistant to antibiotics.

PubMed

Doping-engineered PdRu bimetallic nanoalloys with nitric oxide delivery for synergetic photodynamic therapy.

2026

Dalton transactions (Cambridge, England : 2003)

Jia C, Zhang S, Lv W, Li S, Zhao Y +4 more

Plain English
The study focused on a new treatment for cancer called photodynamic therapy (PDT) using specially designed tiny particles called PdRu nanoalloys that deliver nitric oxide to improve the therapy's effectiveness. Researchers found that these nanoalloys helped kill cancer cells and shrink tumors significantly in mice—almost completely eliminating the tumors without harming other areas of the body. This is important because it shows a new and effective way to fight cancer by combining light therapy with chemical treatment. Who this helps: This helps cancer patients by potentially providing a more effective treatment option with fewer side effects.

PubMed

Temporal Disease Sequence and Prognostic Outcomes in Patients with Coexisting Lung Cancer and Tuberculosis: A 123-Patient Retrospective Cohort Study.

2026

Infection and drug resistance

Yu W, Xie H, Ye B, Lv W, Yu G +4 more

Plain English
This study focused on 123 patients who had both lung cancer and tuberculosis (TB) to understand how the order in which these diseases appear affects symptoms and treatment outcomes. The researchers found that patients diagnosed with both conditions at the same time suffered more severe symptoms and had a higher use of chemotherapy compared to those diagnosed with lung cancer first or TB first. While overall survival rates were similar, those diagnosed first with TB lived for about 32 months, whereas those with lung cancer first had a median survival of 57 months. Who this helps: This information benefits doctors and healthcare providers in making better treatment decisions for patients with both lung cancer and TB.

PubMed

Transcriptomic analysis of gene expression in the longissimus dorsi muscle and liver of Tibetan yaks under different rearing management models in the cold season.

2026

Comparative biochemistry and physiology. Part D, Genomics & proteomics

Zhang Z, Cao Q, Chen Y, Yu Y, Yang X +4 more

Plain English
This study looked at how different feeding and management techniques during the cold season affect the growth and health of Tibetan yaks, focusing on their muscle and liver. Researchers found that changes in diet led to significant changes in gene expression: 3,598 different genes were affected in the muscle and 4,343 in the liver. Understanding these effects can help improve yak management and enhance their growth and meat quality, which is important for farmers and the livestock industry. Who this helps: This helps farmers and livestock managers who raise yaks.

PubMed

10 years trends and hospitalization outcomes of non-neonatal tetanus: a large-scale multicenter retrospective study in China.

2026

Critical care (London, England)

Liu C, Lei M, Chen J, Huang M, Lu Y +163 more

PubMed

Hongwu mixture exerts inhibition on triple-negative breast cancer by regulating SAV1/Hippo signaling through ZNF143.

2026

Mammalian genome : official journal of the International Mammalian Genome Society

Wu A, Ma J, Wang Q, Chen A, Lv W +2 more

Plain English
This study investigated how a mixture of natural ingredients, called Hongwu mixture (HWM), affects triple-negative breast cancer (TNBC) cells. Researchers found that as the dose of HWM increased, the survival rates of TNBC cells decreased significantly, meaning HWM helped slow tumor growth and promote cancer cell death. Specifically, high doses of HWM reduced cell viability and enhanced the cancer cells' ability to die, suggesting it could be an effective treatment option for this aggressive type of breast cancer. Who this helps: This research benefits patients with triple-negative breast cancer by potentially providing a new treatment option.

PubMed

Liver kinase B1 maintains natural killer cell survival by regulating redox homeostasis.

2026

Cell death & disease

Meng W, Luo L, Xiao Z, Huang J, Huang Y +8 more

Plain English
This study focused on a protein called liver kinase B1 (Lkb1) and its role in keeping natural killer (NK) cells—important immune cells that fight viruses and tumors—healthy. Researchers found that without Lkb1, NK cells experienced problems that led to cell death, caused by an overload of harmful substances. Specifically, Lkb1 deficiency caused these cells to struggle with excess reactive oxygen species and disrupted iron balance, which hurt their ability to fight tumors. Who this helps: This research benefits doctors and scientists working on cancer treatments and immune system diseases.

PubMed

Conjugate point matching model for airborne lidar boresight misalignment calibration.

2025

Applied optics

Gu Q, Zhang H, Zhou Y, He Y, Chen W +10 more

Plain English
This study looked at improving the accuracy of airborne lidar systems, which use laser technology to create detailed maps from the sky. Researchers developed a new method that only needs two overlapping images to fix alignment issues, which can drastically speed up the calibration process. They found that after using their method, errors were reduced from 0.74 meters to 0.27 meters, and building outline deviations dropped from 4.07 meters to 0.37 meters, making the data much more reliable. Who this helps: This helps surveyors and engineers who rely on precise mapping for construction and land management.

PubMed

Publication data sourced from PubMed . Plain-English summaries generated by AI. Not medical advice.