P Y Raoul

UOC di Nutrizione Clinica, Dipartimento di Scienze Mediche e Chirurgiche, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo A. Gemelli 8, 00168 Rome, Italy.

47 publications 1976 – 2026 ORCID

What does P Y Raoul research?

P Y Raoul studies how different diets can affect health, especially in patients with cancer undergoing treatments like radiation therapy. They have explored the ketogenic diet and its impact on women with cervical and endometrial cancers. Additionally, they investigate the health effects of ultra-processed foods, finding that these foods can harm gut health and potentially lead to diseases such as diabetes and cancer. Raoul is also examining ancient grains like sorghum as a gluten-free option that could benefit those with celiac disease.

Key findings

  • In a study of 33 patients with cervical and endometrial cancer, both ketogenic and Mediterranean diets were found to have similar adherence levels and side effects during radiation therapy.
  • Ultra-processed foods were shown to decrease gut bacteria diversity and increase harmful bacteria, contributing to chronic inflammation linked to type 2 diabetes and colorectal cancer.
  • Initial findings suggest that sorghum can help reduce inflammation and manage blood sugar in celiac disease patients, although further studies are needed.

Frequently asked questions

Does Dr. Raoul study cancer diets?
Yes, Dr. Raoul studies the effects of specific diets like the ketogenic diet on cancer patients undergoing treatments.
What foods does Dr. Raoul recommend for gut health?
Dr. Raoul's research highlights the importance of avoiding ultra-processed foods to maintain a healthy gut microbiome.
Is Dr. Raoul's work relevant to celiac disease patients?
Yes, Dr. Raoul's research on sorghum provides potential gluten-free dietary options for patients with celiac disease.

Publications in plain English

Post-surgical diets in the ERAS protocol: D-ERAS scoping review.

2026

European journal of clinical nutrition

Fiorindi C, Raoul P, Moretto V, Trestini I, Rossini L +7 more

Plain English
This study looked at how hospitals manage diets for patients after abdominal surgeries as part of the Enhanced Recovery After Surgery (ERAS) program, which recommends starting solid food within 24 hours after surgery to help patients recover faster. The researchers reviewed 68 studies and found that many hospitals waited much longer than suggested to start feeding patients; for example, after colorectal surgeries, most patients only received liquids instead of solid food right away. This matters because the lack of consistency in how hospitals apply these guidelines could slow down recovery and lead to unnecessary complications. Who this helps: This helps patients recovering from abdominal surgery.

PubMed

Clinical Tolerability and Safety of Ketogenic Diet in Patients with Gynecological Malignancies Undergoing Radiotherapy: Preliminary Results of a Prospective, Randomized, Open-Label Trial (KOMPARC).

2026

Nutrients

Cintoni M, Autorino R, Rinaldi RM, Leonardi E, Palombaro M +8 more

Plain English
Researchers studied the effects of a ketogenic diet compared to a standard Mediterranean diet in 33 patients with cervical and endometrial cancer who were undergoing radiation therapy. They found that both diets had similar levels of adherence and no significant differences in side effects like nausea, diarrhea, or weight loss. However, both groups did lose weight during treatment, and those on the ketogenic diet reported more appetite loss and concerns about their weight. Who this helps: This research helps cancer patients receiving radiation therapy by exploring nutritional options that may support their treatment.

PubMed

The Interplay Between the Gut Microbiota and Colorectal Cancer: A Review of the Literature.

2025

Microorganisms

Cintoni M, Palombaro M, Zoli E, D'Agostino G, Pulcini G +7 more

Plain English
This study looked at how the bacteria in our gut, known as the gut microbiota, affect the risk and treatment of colorectal cancer (CRC). Researchers found that an imbalance in gut bacteria, known as dysbiosis, is common among CRC patients and linked to worse outcomes, like more severe tumors and issues with treatment. Eating a diet low in fiber and high in processed foods can raise CRC risk, while a high-fiber diet can help protect against it; restoring a healthy gut microbiota might also improve treatment results and reduce side effects. Who this helps: This information benefits patients with colorectal cancer and healthcare providers involved in their care.

PubMed

Impact of Artificial Sweeteners on Inflammation Markers: A Systematic Review of Animal Studies.

2025

Nutrients

Raoul PC, Romano M, Galli FS, Cintoni M, Capristo E +4 more

Plain English
This study looked at how artificial sweeteners, such as aspartame and sucralose, affect inflammation in the body by reviewing 37 animal studies. It found that both aspartame and sucralose may increase inflammation markers, with sucralose also harming gut health. Understanding these impacts is important because it could help people make better choices about their diet and health, especially when considering the rising use of these sweeteners in processed foods. Who this helps: Patients and consumers concerned about their dietary choices and inflammation-related health issues.

PubMed

The Detrimental Impact of Ultra-Processed Foods on the Human Gut Microbiome and Gut Barrier.

2025

Nutrients

Rondinella D, Raoul PC, Valeriani E, Venturini I, Cintoni M +8 more

Plain English
This research paper looks at how ultra-processed foods, which often contain artificial ingredients and low fiber, negatively affect gut health. It found that these foods decrease the diversity of good bacteria in our gut while increasing harmful ones, leading to chronic inflammation linked to conditions like type 2 diabetes and colorectal cancer. This is important because it highlights the need for better dietary choices and regulations on ultra-processed foods to improve health outcomes. Who this helps: This benefits patients at risk for chronic diseases and healthcare providers looking to improve dietary recommendations.

PubMed

Microbiota-Gastric Cancer Interactions and the Potential Influence of Nutritional Therapies.

2024

International journal of molecular sciences

Raoul P, Maccauro V, Cintoni M, Scarpellini E, Ianiro G +3 more

Plain English
This study looked at how the bacteria in our stomach, mouth, and gut interact and how they might affect gastric cancer (GC) and its treatment. The researchers found that changes in these bacteria can influence the development of GC and how well treatments work, and they believe that nutritional therapies like diet changes and probiotics could play a crucial role in managing the disease. Understanding these relationships could lead to new ways to detect and treat gastric cancer more effectively. Who this helps: This helps patients with gastric cancer and their doctors.

PubMed

Impact of body composition parameters on radiation therapy compliance in locally advanced rectal cancer: A retrospective observational analysis.

2024

Clinical and translational radiation oncology

Chiloiro G, Cintoni M, Palombaro M, Romano A, Reina S +11 more

Plain English
Researchers looked at how body composition, particularly muscle mass and fat, affects the treatment success of patients with locally advanced rectal cancer. They studied 628 patients and found that those with low muscle mass were more likely to have their radiation therapy interrupted, while higher muscle mass and lower fat levels were linked to better survival rates. This matters because understanding these body composition factors can help doctors better manage treatment and improve outcomes for these patients. Who this helps: This helps patients undergoing treatment for locally advanced rectal cancer and the healthcare providers who support them.

PubMed

Gastric Cancer, Immunotherapy, and Nutrition: The Role of Microbiota.

2024

Pathogens (Basel, Switzerland)

Raoul P, De Gaetano V, Sciaraffia G, Ormea G, Cintoni M +5 more

Plain English
This research examined the links between gut bacteria, diet, and the effectiveness of immunotherapy for stomach cancer, which is a leading cause of cancer deaths. It found that the makeup of gut bacteria and nutritional health can significantly impact how well patients respond to treatment and their chances of survival. For instance, a better diet might improve immune responses and overall health during treatment. Who this helps: This helps stomach cancer patients by highlighting the importance of diet and gut health in their treatment.

PubMed

Preoperative low skeletal muscle mass index assessed using L3-CT as a prognostic marker of clinical outcomes in pancreatic cancer patients undergoing surgery: a systematic review and meta-analysis.

2024

International journal of surgery (London, England)

Raoul P, Cintoni M, Coppola A, Alfieri S, Tortora G +3 more

Plain English
This research looked at how low muscle mass in pancreatic cancer patients, measured using a specific type of scan, affects their recovery after surgery. They found that more than half (50.9%) of patients had low muscle mass before surgery, and those patients had a 52% higher risk of not surviving as long after the operation. Understanding muscle mass can help doctors predict patient outcomes and emphasizes the need for nutritional support to improve recovery. Who this helps: This helps patients with pancreatic cancer and their doctors.

PubMed

Assessing Quality of Life with the Novel QLQ-CAX24 Questionnaire and Body Composition Parameters in Rectal Cancer Patients: A Single-Center Prospective Study.

2024

Nutrients

Cintoni M, Palombaro M, Raoul P, Chiloiro G, Romano A +11 more

Plain English
This study looked at how body composition and physical strength affect the quality of life in patients with locally advanced rectal cancer. Researchers analyzed data from 56 patients and found that important factors like muscle mass and nutritional status were strongly linked to quality of life scores; for example, patients with lower muscle mass reported poorer quality of life. This is important because it highlights the need for monitoring and addressing body composition issues during treatment to help improve patients' well-being. Who this helps: This helps rectal cancer patients and their healthcare providers.

PubMed

Sorghum (Sorghum vulgare): an ancient grain, a novel choice for a healthy gluten-free diet.

2024

Minerva gastroenterology

Dionisi T, Rinninella E, Raoul P, Cintoni M, Mele MC +6 more

Plain English
This research focused on sorghum, an ancient grain that could be a healthy addition to gluten-free diets for people with celiac disease (CD). It found that sorghum contains beneficial compounds that can help reduce inflammation, manage blood sugar, and lower cholesterol, making it potentially good for those struggling with CD. While there is some initial evidence that it can be safe for celiac patients, more long-term studies are needed to confirm its benefits. Who this helps: This research benefits patients with celiac disease who need gluten-free food options.

PubMed

Hospital Services to Improve Nutritional Intake and Reduce Food Waste: A Systematic Review.

2023

Nutrients

Rinninella E, Raoul P, Maccauro V, Cintoni M, Cambieri A +4 more

Plain English
This study looked at how different hospital services can improve what patients eat while also reducing the amount of food that gets wasted. Researchers reviewed 19 studies and found that personalized meal options and efficient room service can help patients eat better and waste less food. This is important because improving nutrition can lead to better health outcomes for patients and lessen the environmental impact of food waste. Who this helps: Patients in hospitals and healthcare providers focused on nutrition.

PubMed

COntrolling NUTritional Status (CONUT) as Predictive Score of Hospital Length of Stay (LOS) and Mortality: A Prospective Cohort Study in an Internal Medicine and Gastroenterology Unit in Italy.

2023

Nutrients

Rinninella E, Borriello R, D'Angelo M, Galasso T, Cintoni M +5 more

Plain English
Researchers studied how well the COntrolling NUTritional status (CONUT) score could predict how long patients would stay in the hospital and their chances of dying while hospitalized. They found that out of 203 patients, those with moderate to severe malnutrition (CONUT score of 5 or higher) had longer hospital stays, with an average of over 8 days, and a higher risk of death, particularly if their score was over 8. This is important because using the CONUT score can help doctors identify at-risk patients early and manage their nutrition better, potentially improving outcomes. Who this helps: This helps patients in the hospital, particularly those at risk of malnutrition.

PubMed

The role of diet in shaping human gut microbiota.

2023

Best practice & research. Clinical gastroenterology

Rinninella E, Tohumcu E, Raoul P, Fiorani M, Cintoni M +4 more

Plain English
This paper studied how different diets affect the bacteria that live in our guts, which are important for our health. It found that what we eat can significantly change the types of bacteria present, influencing our immune system and gut barrier. For example, certain nutrients can either help or harm our gut bacteria, which can impact various diseases. Understanding this connection is important for developing new nutrition-based treatments for health issues. Who this helps: This helps patients and healthcare providers looking for new ways to improve gut health and manage diseases.

PubMed

Special Issue "Gastrointestinal Microbiota and Gut Barrier Impact Human Health and Disease": Editorial.

2023

Microorganisms

Raoul P, Cintoni M, Rinninella E, Mele MC

Plain English
This study focuses on the link between gut bacteria and overall health. It highlights that an imbalance in gut microbiota can worsen conditions like obesity, diabetes, and heart disease, which are becoming more common worldwide. Understanding this connection is crucial because improving gut health can help prevent or treat these serious diseases. Who this helps: This helps patients at risk of or suffering from diseases related to gut health.

PubMed

Targeting the Gut Microbiota in Kidney Disease: The Future in Renal Nutrition and Metabolism.

2023

Journal of renal nutrition : the official journal of the Council on Renal Nutrition of the National Kidney Foundation

Lambert K, Rinninella E, Biruete A, Sumida K, Stanford J +4 more

Plain English
This study focuses on how the gut bacteria of people with chronic kidney disease (CKD) can be changed to improve their health. It found that CKD patients often have an unhealthy balance of gut bacteria, which can lead to more health problems. By using plant-based diets and supplements like probiotics, this imbalance can potentially be corrected, offering a new approach to managing kidney disease. Who this helps: This helps patients with chronic kidney disease.

PubMed

Metabolic Disorders and Psoriasis: Exploring the Role of Nutritional Interventions.

2023

Nutrients

Cintoni M, Palombaro M, Maramao FS, Raoul P, Egidi G +6 more

Plain English
This study looked at how diet and lifestyle changes can affect psoriasis, a long-term skin condition often linked to health issues like obesity and diabetes. The findings indicate that maintaining a healthy weight and following a Mediterranean diet, which is high in fiber and vitamins, can lead to less severe psoriasis symptoms. This information is important because it shows that simple dietary changes can improve health for those with psoriasis. Who this helps: Patients with psoriasis can benefit from these dietary recommendations.

PubMed

The Role of Gut Microbiota and Leaky Gut in the Pathogenesis of Food Allergy.

2023

Nutrients

Poto R, Fusco W, Rinninella E, Cintoni M, Kaitsas F +7 more

Plain English
This study looked at how the bacteria in our gut and the health of our intestinal lining might influence the rise of food allergies, especially in Western countries. Researchers found that poor gut health and a "leaky" gut can allow harmful substances to enter the body, leading to allergic reactions. They also noted that treatments like probiotics and fecal transplants show promise in preventing and treating food allergies by improving gut health. Who this helps: This helps patients with food allergies and those at risk of developing them.

PubMed

Vitamin D and colorectal cancer: Chemopreventive perspectives through the gut microbiota and the immune system.

2022

BioFactors (Oxford, England)

Rinninella E, Mele MC, Raoul P, Cintoni M, Gasbarrini A

Plain English
This study focused on the relationship between vitamin D and colorectal cancer (CRC), examining how vitamin D influences the immune system and gut bacteria. It found that vitamin D may help prevent CRC by affecting immune responses and maintaining a healthy gut microbiome. Understanding these connections is important because it could lead to better prevention strategies for colorectal cancer. Who this helps: This helps patients at risk for colorectal cancer and healthcare providers looking for preventive measures.

PubMed

The prognostic value of skeletal muscle index on clinical and survival outcomes after cytoreduction and HIPEC for peritoneal metastases from colorectal cancer: A systematic review and meta-analysis.

2022

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology

Di Giorgio A, Rotolo S, Cintoni M, Rinninella E, Pulcini G +8 more

Plain English
This study looked at how the amount of muscle mass in the body affects recovery and survival in patients with colorectal cancer that has spread to the abdominal area, specifically those undergoing surgery and chemotherapy treatment. Researchers found that patients with low muscle mass had a 45% higher risk of developing complications after surgery. This is important because it highlights the need to consider muscle health in treatment planning, as improving muscle mass could lead to better patient outcomes. Who this helps: Patients with colorectal cancer and their doctors.

PubMed

Food Additives, a Key Environmental Factor in the Development of IBD through Gut Dysbiosis.

2022

Microorganisms

Raoul P, Cintoni M, Palombaro M, Basso L, Rinninella E +2 more

Plain English
This study looked at how food additives in processed foods affect gut health and could trigger inflammatory bowel disease (IBD). Researchers found that certain artificial ingredients, like emulsifiers and sweeteners, can harm the gut’s bacteria and lead to chronic inflammation. This is important because it highlights the need for IBD patients to avoid processed foods and work with nutritionists for healthier diets. Who this helps: This helps patients with inflammatory bowel disease and their healthcare providers.

PubMed

Clinical Impact of Nutritional Status and Sarcopenia in Pediatric Patients with Bone and Soft Tissue Sarcomas: A Pilot Retrospective Study (SarcoPed).

2022

Nutrients

Romano A, Triarico S, Rinninella E, Natale L, Brizi MG +8 more

Plain English
This study looked at the nutritional and muscle health of children with bone and soft tissue cancers. It found that 57.1% of the 21 patients had low muscle mass (sarcopenia) when they were diagnosed, and most showed decreases in body weight and muscle area after 12 months of treatment. The research highlights that a drop in nutritional health is linked to worse survival chances, especially if patients have metastasis or do not undergo surgery. Who this helps: This helps doctors and healthcare providers understand the importance of monitoring nutrition and muscle mass in young cancer patients.

PubMed

Incidence and Impact of Refeeding Syndrome in an Internal Medicine and Gastroenterology Ward of an Italian Tertiary Referral Center: A Prospective Cohort Study.

2022

Nutrients

Rinninella E, D'Angelo M, Borriello R, Galasso T, Cintoni M +5 more

Plain English
This study looked at refeeding syndrome (RS) in patients at an Italian medical center, especially those who were malnourished and received rapid nutrition after fasting. Researchers found that nearly half (48.3%) of the 203 patients were at risk for RS, and it actually occurred in 38 patients (18.7%), leading to longer hospital stays (12.5 days compared to 7.1 days for those without RS). RS is linked to a higher chance of death, with factors like a low body mass index and delayed nutritional support increasing that risk. Who this helps: This information benefits doctors and healthcare providers, helping them recognize and manage at-risk patients.

PubMed

Lipid-Enriched Parenteral Nutrition and Bloodstream Infections in Hospitalized Patients: Is It a Real Concern?

2022

Medicina (Kaunas, Lithuania)

Tota A, Serra A, Raoul P, Gasbarrini A, Rinninella E +1 more

Plain English
This study looked into whether giving patients lipid-enriched parenteral nutrition (a type of feeding through an IV) increases the risk of bloodstream infections. The findings showed that there is no solid evidence from recent studies that lipids significantly raise this risk. In fact, these lipids are crucial for providing energy and important nutrients to patients who are often malnourished, which can help improve their overall health. Who this helps: This benefits hospitalized patients who require nutritional support.

PubMed

Food Emulsifiers and Metabolic Syndrome: The Role of the Gut Microbiota.

2022

Foods (Basel, Switzerland)

De Siena M, Raoul P, Costantini L, Scarpellini E, Cintoni M +3 more

Plain English
This study looked at how food emulsifiers, which are ingredients used in many processed foods, might affect our gut bacteria and lead to metabolic syndrome, a condition that increases the risk of diabetes and heart disease. Researchers found that some emulsifiers can change gut bacteria in ways that could lead to metabolic disorders, while others might actually have beneficial effects on gut health. However, there are still many unknowns about how much emulsifier is safe to eat and how they interact with different people's gut bacteria. Who this helps: This helps patients concerned about metabolic health and healthcare providers advising on nutrition.

PubMed

Impact of Diet on Gut Microbiota Composition and Microbiota-Associated Functions in Heart Failure: A Systematic Review of In Vivo Animal Studies.

2022

Metabolites

Palombaro M, Raoul P, Cintoni M, Rinninella E, Pulcini G +4 more

Plain English
This study looked at how different diets affect gut bacteria and heart failure in animals. It found that high-fiber and prebiotic diets can improve heart failure symptoms, like lowering blood pressure and reducing heart enlargement. In contrast, high-fat and choline-rich diets worsened heart function and increased inflammation. This matters because it highlights the importance of diet in managing heart failure, offering a potential way to improve treatment. Who this helps: This helps patients with heart failure by showing how diet can impact their health.

PubMed

Prognostic value of skeletal muscle mass during tyrosine kinase inhibitor (TKI) therapy in cancer patients: a systematic review and meta-analysis.

2021

Internal and emergency medicine

Rinninella E, Cintoni M, Raoul P, Ponziani FR, Pompili M +6 more

Plain English
This research looked at how low muscle mass affects cancer patients who are receiving a type of treatment known as tyrosine kinase inhibitors (TKIs). The study found that patients with low muscle mass had a 2.4 times greater risk of experiencing harmful side effects from the treatment and that those with low muscle mass who were treated for liver cancer (HCC) with sorafenib had a 45% higher risk of dying compared to those with more muscle mass. This matters because understanding the role of muscle mass can help improve treatment plans and outcomes for cancer patients undergoing TKI therapy. Who this helps: This helps cancer patients and their doctors in managing treatment risks and potential survival outcomes.

PubMed

Impact of Food Additive Titanium Dioxide on Gut Microbiota Composition, Microbiota-Associated Functions, and Gut Barrier: A Systematic Review of In Vivo Animal Studies.

2021

International journal of environmental research and public health

Rinninella E, Cintoni M, Raoul P, Mora V, Gasbarrini A +1 more

Plain English
This study looked at how titanium dioxide (a common food additive) affects the gut bacteria and overall gut health in animals. The findings showed that exposure to titanium dioxide can change the types of bacteria present, reduce the production of important substances that help with gut health, and increase inflammation in the gut. This matters because it raises questions about the safety of using titanium dioxide in food and suggests that it might harm gut health in the long run. Who this helps: This information helps patients who may be affected by food additives and health professionals concerned about dietary safety.

PubMed

Body Composition Changes in Gastric Cancer Patients during Preoperative FLOT Therapy: Preliminary Results of an Italian Cohort Study.

2021

Nutrients

Rinninella E, Strippoli A, Cintoni M, Raoul P, Vivolo R +8 more

Plain English
This study looked at how a new chemotherapy treatment called FLOT affects body composition in patients with advanced gastric cancer. Researchers found that after treatment, patients experienced significant weight loss and a decrease in muscle mass: their average body mass index (BMI) dropped from 24.4 to 22.6, and skeletal muscle index decreased from 48.74 to 46.52. Interestingly, while these changes in body composition did not affect short-term treatment outcomes, a decrease in muscle mass of over 5% was linked to better tumor regression. Who this helps: This research benefits gastric cancer patients and their doctors by providing insight into how treatment impacts body composition.

PubMed

Gut Microbiota and Environment in Coronary Artery Disease.

2021

International journal of environmental research and public health

Piccioni A, de Cunzo T, Valletta F, Covino M, Rinninella E +4 more

Plain English
This study looked at how the bacteria in our intestines (gut microbiota) and factors like pollution and Western diets relate to coronary artery disease (CAD), the top cause of death in Western countries. The research showed that people with CAD have different gut bacteria than healthy individuals, but the findings were mixed. Understanding these links is important because they could lead to new ways to prevent or treat CAD. Who this helps: This helps patients at risk of heart disease and doctors looking for better treatment options.

PubMed

NutriCatt Protocol Improves Body Composition and Clinical Outcomes in Elderly Patients Undergoing Colorectal Surgery in ERAS Program: A Retrospective Cohort Study.

2021

Nutrients

Rinninella E, Biondi A, Cintoni M, Raoul P, Scialanga F +7 more

Plain English
This study looked at how a special nutrition program called NutriCatt affects older patients undergoing colorectal surgery. Researchers found that patients on the NutriCatt program had better body health markers and experienced fewer serious complications and shorter hospital stays compared to those who followed standard care. Specifically, those using NutriCatt had significant improvements in body composition and a 90% lower risk of severe complications. Who this helps: This benefits elderly patients undergoing colorectal surgery and their healthcare providers.

PubMed

Nutritional Interventions Targeting Gut Microbiota during Cancer Therapies.

2021

Microorganisms

Rinninella E, Raoul P, Cintoni M, Palombaro M, Pulcini G +2 more

Plain English
This study looked at how changes in diet, specifically nutritional interventions like prebiotics and dietary strategies, can affect the gut bacteria of cancer patients during their treatments. The research found that these dietary changes can improve the diversity of gut bacteria, which may help reduce side effects and enhance treatment responses. Understanding this connection matters because it opens new ways to support cancer patients through their therapies, potentially improving their overall experience and outcomes. Who this helps: This helps cancer patients undergoing treatment.

PubMed

Muscle mass, assessed at diagnosis by L3-CT scan as a prognostic marker of clinical outcomes in patients with gastric cancer: A systematic review and meta-analysis.

2020

Clinical nutrition (Edinburgh, Scotland)

Rinninella E, Cintoni M, Raoul P, Pozzo C, Strippoli A +4 more

Plain English
This study examined the importance of muscle mass in patients with stomach cancer, specifically looking at how muscle mass measured by a CT scan at the L3 vertebra affects survival and recovery after treatment. They found that 32.7% of these patients had low muscle mass, which was linked to a more than double risk of death and a decreased chance of staying cancer-free after treatment. For patients with low muscle mass, there was also a higher likelihood of complications and longer hospital stays. Who this helps: This research benefits stomach cancer patients and their healthcare teams, including doctors and nutritionists.

PubMed

Skeletal muscle mass as a prognostic indicator of outcomes in ovarian cancer: a systematic review and meta-analysis.

2020

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Rinninella E, Fagotti A, Cintoni M, Raoul P, Scaletta G +3 more

Plain English
This research looked at how muscle mass and quality can predict outcomes for women with ovarian cancer. The study found that while overall muscle mass alone did not strongly link to survival rates, lower muscle quality (specifically low muscle radiodensity) was associated with higher risk of poor outcomes, with a significant increase in risk of death by 63% (HR 1.63). Understanding these factors can help doctors identify at-risk patients and tailor nutritional strategies to improve care. Who this helps: This helps patients with ovarian cancer.

PubMed

Effects of nutritional interventions on nutritional status in patients with gastric cancer: A systematic review and meta-analysis of randomized controlled trials.

2020

Clinical nutrition ESPEN

Rinninella E, Cintoni M, Raoul P, Pozzo C, Strippoli A +4 more

Plain English
This research looked at different nutritional support strategies for people with stomach cancer who are undergoing surgery or chemotherapy. The study found that those who received oral nutritional supplements (ONS) lost less body weight compared to those who didn't, with a difference of 0.77 kilograms. Additionally, enteral nutrition (EN) significantly increased certain protein levels in the blood, like prealbumin, highlighting its potential benefits for patients. Who this helps: This helps patients with stomach cancer who are receiving treatment and their healthcare providers.

PubMed

Gut Microbiota during Dietary Restrictions: New Insights in Non-Communicable Diseases.

2020

Microorganisms

Rinninella E, Cintoni M, Raoul P, Ianiro G, Laterza L +4 more

Plain English
This study looked at how dietary restrictions influence gut bacteria and their role in serious health issues like obesity, diabetes, and cancer. It found that these dietary changes can improve the balance of gut bacteria, potentially slowing down age-related health decline and helping to prevent these diseases. This is important because a healthier gut microbiome may lead to better metabolism and even brain function, helping people live healthier, longer lives. Who this helps: Patients looking to improve their health and prevent chronic diseases.

PubMed

The Facts about Food after Cancer Diagnosis: A Systematic Review of Prospective Cohort Studies.

2020

Nutrients

Rinninella E, Mele MC, Cintoni M, Raoul P, Ianiro G +6 more

Plain English
This research paper looked at how diet after a cancer diagnosis affects patient outcomes. It found that eating a low-fat, high-quality diet with plenty of fiber and protein can be good for cancer patients, while a Western diet high in saturated fats may increase the risk of death. Since many cancer patients struggle with nutrition and often rely on questionable diets, these findings highlight the importance of proper dietary guidance for better health outcomes. Who this helps: This helps cancer patients and their caregivers.

PubMed

Skeletal Muscle Loss during Multikinase Inhibitors Therapy: Molecular Pathways, Clinical Implications, and Nutritional Challenges.

2020

Nutrients

Rinninella E, Cintoni M, Raoul P, Pozzo C, Strippoli A +6 more

Plain English
This study looked at how cancer treatments called tyrosine kinase inhibitors (TKIs) affect muscle loss in patients. It found that patients receiving TKIs, like sorafenib and sunitinib, can suffer significant muscle loss, which is linked to worse treatment outcomes and lower survival rates. Recognizing and addressing this loss through better nutrition could help patients endure treatments and improve their chances of recovery. Who this helps: This supports cancer patients undergoing TKI therapy by highlighting the importance of monitoring and maintaining muscle mass.

PubMed

Food Additives, Gut Microbiota, and Irritable Bowel Syndrome: A Hidden Track.

2020

International journal of environmental research and public health

Rinninella E, Cintoni M, Raoul P, Gasbarrini A, Mele MC

Plain English
This study looked at how food additives in our diets might affect gut bacteria and contribute to irritable bowel syndrome (IBS). It found that certain food additives can disturb the balance of gut bacteria, leading to symptoms like stomach pain and inflammation. Specifically, these changes might worsen IBS symptoms, highlighting the importance of being cautious about food additives in diets. Who this helps: This benefits patients with IBS.

PubMed

What is the Healthy Gut Microbiota Composition? A Changing Ecosystem across Age, Environment, Diet, and Diseases.

2019

Microorganisms

Rinninella E, Raoul P, Cintoni M, Franceschi F, Miggiano GAD +2 more

Plain English
This study examined how the composition of gut bacteria varies among individuals and how it changes with age, environment, diet, and health conditions. Researchers found that while each person's gut microbiota is unique and influenced by factors like birth method and antibiotic use, a healthy balance is crucial for proper metabolism and immune function. Understanding these variations is important because an imbalance, known as dysbiosis, is linked to various health issues, including both digestive and neurological problems. Who this helps: This helps patients, especially those with digestive issues or chronic diseases.

PubMed

Nutritional Interventions to Improve Clinical Outcomes in Ovarian Cancer: A Systematic Review of Randomized Controlled Trials.

2019

Nutrients

Rinninella E, Fagotti A, Cintoni M, Raoul P, Scaletta G +5 more

Plain English
This study looked at how different nutritional approaches can help improve the health and recovery of women with ovarian cancer. Researchers reviewed 14 trials and found that early feeding after surgery can reduce hospital stay and help the gut recover faster. Other methods, like certain diets and food supplements, also showed promise but highlighted a need for more thorough research to provide clearer results. Who this helps: This benefits ovarian cancer patients by identifying dietary strategies that can improve their recovery and overall survival.

PubMed

Food Components and Dietary Habits: Keys for a Healthy Gut Microbiota Composition.

2019

Nutrients

Rinninella E, Cintoni M, Raoul P, Lopetuso LR, Scaldaferri F +4 more

Plain English
This study looked at how different foods and diets affect the bacteria living in our guts, which play a key role in our overall health. It found that modern eating habits, especially high sugar and Western diets, are linked to imbalances in gut bacteria that can lead to obesity and other health issues. Understanding which foods promote a healthy gut microbiome is vital because it can inform better dietary choices to help prevent diseases. Who this helps: This benefits patients seeking to improve their gut health and doctors advising on nutrition.

PubMed

Minimal impact of lenvatinib (Lenvima®) on muscle mass in advanced hepatocellular carcinoma and implications for treatment duration. Two cases from the REFLECT study.

2019

European review for medical and pharmacological sciences

Rinninella E, Cintoni M, Raoul P, Mele MC, De Gaetano AM +3 more

Plain English
This study looked at how the cancer drug lenvatinib (Lenvima®) affects muscle mass in two men with advanced liver cancer over nearly two years. They found that one patient had a slight decrease in muscle mass of about 2.13%, while the other experienced a more significant loss of 10.83%, but both had stable disease during treatment. This is important because it shows that lenvatinib may not cause significant muscle loss, which can help shape support strategies for patients undergoing this treatment. Who this helps: Patients with advanced liver cancer.

PubMed

Effect of two doses of ginkgo biloba extract (EGb 761) on the dual-coding test in elderly subjects.

1993

Clinical therapeutics

Allain H, Raoul P, Lieury A, LeCoz F, Gandon JM +1 more

Plain English
This study looked at how two different doses of Ginkgo biloba extract affect the speed of information processing in 18 older adults with mild memory issues. The researchers found that after taking Ginkgo biloba, participants could process information faster, with key improvements shown by a shift in their performance times from 960 milliseconds to 480 milliseconds for the break point, and from 1920 milliseconds to 960 milliseconds for dual coding. This matters because it suggests that Ginkgo biloba can help enhance cognitive processing speed in older adults. Who this helps: This helps elderly patients with memory difficulties.

PubMed

[Memory deficit in Parkinson's disease. Precocious aging of recall processes].

1992

Presse medicale (Paris, France : 1983)

Raoul P, Lieury A, Decombe R, Chauvel P, Allain H

Plain English
This study looked at how memory works in 25 people with Parkinson's disease who do not have dementia. The researchers found that these patients had trouble recalling words and drawings, while their ability to recognize drawings and faces remained intact. These memory issues were linked to their age, but not to the severity of their Parkinson's symptoms, suggesting that Parkinson's affects memory differently than normal aging. Who this helps: This helps patients with Parkinson's disease and their caregivers.

PubMed

[Successive bilateral adrenal phaeochromocytoma. One case (author's transl)].

1978

La Nouvelle presse medicale

Logeais Y, Solovei G, Raoul PY, Louvet M, Cadot M +1 more

Plain English
This study reported on a patient who had two surgeries for adrenal phaeochromocytomas, which are rare tumors that affect the adrenal glands. The patient had her first surgery at age 10 for a tumor on one side, and then a second surgery at age 27 for a tumor on the opposite side. These tumors can be tricky to treat, often requiring the removal of both adrenal glands and hormone therapy afterward to manage hormone levels. Who this helps: This research benefits patients with adrenal tumors and their doctors, particularly those managing complex cases.

PubMed

[Unilateral auricular paralysis and dissociated ectopic auricular rhythm. Apropos of 4 cases].

1976

Archives des maladies du coeur et des vaisseaux

Fauchier JP, Raynaud R, Brochier M, Raynaud P, Raoul PY

Plain English
This study looked at four older patients who had issues with their heart rhythms, specifically a problem called right atrial palsy, which was linked to either a fast or slow heartbeat from the left side of their hearts. The patients, all with a long history of heart problems, showed signs of various heart block conditions. This is important because it highlights the need for careful testing and possible treatments, like pacemakers, to manage these complex heart rhythm issues effectively. Who this helps: This benefits elderly patients with heart problems and their doctors.

PubMed

Publication data sourced from PubMed . Plain-English summaries generated by AI. Not medical advice.